Page last updated: 2024-11-12

gamma-endorphin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

gamma-Endorphin: An endogenous opioid peptide derived from BETA-LIPOTROPIN of the pro-opiomelanocortin (POMC) system. It is the 17-amino acid sequence of the N-terminal of BETA-ENDORPHIN and differs from ALPHA-ENDORPHIN by one amino acid (beta-endorphin 1-16). [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16138008
MeSH IDM0028179

Synonyms (8)

Synonym
gamma-endorphin
endorphin, gamma
61512-77-4
lipotropin 61-77
a65g32vj2m ,
unii-a65g32vj2m
Q5520266
h-tyr-gly-gly-phe-met-thr-ser-glu-lys-ser-gln-thr-pro-leu-val-thr-leu-oh

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" gamma E (beta-LPH-(61-77)), beta-endorphin-(1-17)), and DT gamma E (beta-LPH-(62-77), beta-endorphin-(2-17)) were without effect in the dosage used."( The effect of gamma-type endorphins on alpha-MSH release in the rat.
Andringa-Bakker, EA; de Rotte, AA; de Wied, D; van de Buuse, M; van Wimersma Greidanus, TB, 1985
)
0.27
" Dose-response studies revealed that a dose of 100 pg DE gamma E completely inhibited the apomorphine-induced hypomotility."( Non-opiate beta-endorphin fragments and dopamine--III. gamma-Type endorphins and various neuroleptics counteract the hypoactivity elicited by injection of apomorphine into the nucleus accumbens.
Caffé, AR; Van Ree, JM; Wolterink, G, 1982
)
0.26
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (96)

TimeframeStudies, This Drug (%)All Drugs %
pre-199079 (82.29)18.7374
1990's16 (16.67)18.2507
2000's1 (1.04)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 18.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index18.50 (24.57)
Research Supply Index4.74 (2.92)
Research Growth Index3.94 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (18.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials4 (3.67%)5.53%
Reviews6 (5.50%)6.00%
Case Studies1 (0.92%)4.05%
Observational0 (0.00%)0.25%
Other98 (89.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]