succimer has been researched along with Neuroblastoma* in 2 studies
2 other study(ies) available for succimer and Neuroblastoma
| Article | Year |
|---|---|
Pentavalent technetium-99m dimercaptosuccinic acid scintigraphy is useful in diagnosis and localization of neuroblastoma.
Topics: Humans; Neuroblastoma; Organotechnetium Compounds; Radionuclide Imaging; Sensitivity and Specificity; Succimer; Technetium Tc 99m Dimercaptosuccinic Acid | 1992 |
Differential responses to methylmercury exposure and recovery in neuroblastoma and glioma cells and fibroblasts.
The effects of methylmercury (MeHg) on cytoplasmic microtubules in cultured neuroblastoma cells, glioma cells, and fibroblasts were compared. Neuroblastoma cells appeared to be more sensitive to disruption of microtubules by MeHg than the glioma cells or fibroblasts; cellular concentrations of mercury after MeHg were also higher in neuroblastoma cells. Recovery of microtubule structure was monitored in cells after removal of MeHg; addition of the chelating dimercaptosuccinic acid (DMSA) increased reassembly of microtubules. During MeHg treatment and early recovery, microtubule integrity was dependent on cellular mercury concentrations. However, after prolonged DMSA exposure, mercury appeared to reenter the cell, without causing dissociation of microtubules. Topics: Animals; Fibroblasts; Fluorescent Antibody Technique; Glioma; Methylmercury Compounds; Microtubules; Nervous System; Neuroblastoma; Rats; Succimer; Time Factors | 1984 |