carbamates has been researched along with Neuroblastoma in 14 studies
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In these lines, we confirmed the effects of 2-arachidonoylglycerol (2-AG), the main endocannabinoid, on neuroblastoma cells proliferation in vitro, and proved that some N-phenylmaleimide compounds that were previously shown as MAGL inhibitors can also inhibit type 2 topoisomerase." | 7.78 | Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growth. ( Baldeyroux, B; Hamtiaux, L; Lambert, DM; Lansiaux, A; Matuszak, N; Muccioli, GG; Poupaert, JH, 2012) |
| "We have investigated the effect of ganstigmine (CHF2819), a novel geneserine derived acetylcholinesterase (AChE) inhibitor, on the expression and metabolism of the amyloid precursor protein (APP) in neuroblastoma cell line SH-SY5Y." | 7.72 | Characterization of the effect of ganstigmine (CHF2819) on amyloid precursor protein metabolism in SH-SY5Y neuroblastoma cells. ( Govoni, S; Mazzucchelli, M; Pietra, C; Porrello, E; Racchi, M; Villetti, G, 2003) |
| " In these lines, we confirmed the effects of 2-arachidonoylglycerol (2-AG), the main endocannabinoid, on neuroblastoma cells proliferation in vitro, and proved that some N-phenylmaleimide compounds that were previously shown as MAGL inhibitors can also inhibit type 2 topoisomerase." | 3.78 | Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growth. ( Baldeyroux, B; Hamtiaux, L; Lambert, DM; Lansiaux, A; Matuszak, N; Muccioli, GG; Poupaert, JH, 2012) |
| " Release rates were found to fit well with the chemical model and several conjugates of camptothecin and one of combretastatin were shown to have potent cytotoxic effects on cultures of human neuroblastoma IMR-32 cells which over-express somatostatin receptors." | 3.72 | An adjustable release rate linking strategy for cytotoxin-peptide conjugates. ( Coy, DH; Fuselier, JA; Murphy, WA; Sun, L; Vasilevich, N; Woltering, SN, 2003) |
| "We have investigated the effect of ganstigmine (CHF2819), a novel geneserine derived acetylcholinesterase (AChE) inhibitor, on the expression and metabolism of the amyloid precursor protein (APP) in neuroblastoma cell line SH-SY5Y." | 3.72 | Characterization of the effect of ganstigmine (CHF2819) on amyloid precursor protein metabolism in SH-SY5Y neuroblastoma cells. ( Govoni, S; Mazzucchelli, M; Pietra, C; Porrello, E; Racchi, M; Villetti, G, 2003) |
| "When neuroblastoma cells bearing neurites are incubated with colchicine or Nocodazole, the cytoplasmic microtubules are depolymerized and concomitantly the neurites retract." | 3.66 | Cytochalasin separates microtubule disassembly from loss of asymmetric morphology. ( Magendantz, M; Solomon, F, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, J | 1 |
| Huchthausen, J | 1 |
| Schlichting, R | 1 |
| Scholz, S | 1 |
| Henneberger, L | 1 |
| Escher, BI | 1 |
| Salcher, S | 1 |
| Spoden, G | 1 |
| Huber, JM | 1 |
| Golderer, G | 1 |
| Lindner, H | 1 |
| Ausserlechner, MJ | 1 |
| Kiechl-Kohlendorfer, U | 1 |
| Geiger, K | 1 |
| Obexer, P | 1 |
| Dorneburg, C | 1 |
| Goß, AV | 1 |
| Fischer, M | 1 |
| Roels, F | 1 |
| Barth, TF | 1 |
| Berthold, F | 1 |
| Kappler, R | 1 |
| Oswald, F | 1 |
| Siveke, JT | 1 |
| Molenaar, JJ | 1 |
| Debatin, KM | 1 |
| Beltinger, C | 1 |
| Matuszak, N | 1 |
| Hamtiaux, L | 1 |
| Baldeyroux, B | 1 |
| Muccioli, GG | 1 |
| Poupaert, JH | 1 |
| Lansiaux, A | 1 |
| Lambert, DM | 1 |
| Cagnin, M | 1 |
| Ozzano, M | 1 |
| Bellio, N | 1 |
| Fiorentino, I | 1 |
| Follo, C | 1 |
| Isidoro, C | 1 |
| Fuselier, JA | 1 |
| Sun, L | 1 |
| Woltering, SN | 1 |
| Murphy, WA | 1 |
| Vasilevich, N | 1 |
| Coy, DH | 1 |
| Mazzucchelli, M | 1 |
| Porrello, E | 1 |
| Villetti, G | 1 |
| Pietra, C | 1 |
| Govoni, S | 1 |
| Racchi, M | 1 |
| Parent, AT | 1 |
| Barnes, NY | 1 |
| Taniguchi, Y | 1 |
| Thinakaran, G | 1 |
| Sisodia, SS | 1 |
| Maezawa, I | 1 |
| Hong, HS | 1 |
| Wu, HC | 1 |
| Battina, SK | 1 |
| Rana, S | 1 |
| Iwamoto, T | 1 |
| Radke, GA | 1 |
| Pettersson, E | 1 |
| Martin, GM | 1 |
| Hua, DH | 1 |
| Jin, LW | 1 |
| Solomon, F | 2 |
| Magendantz, M | 1 |
| Figueroa, DJ | 1 |
| Morris, JA | 1 |
| Ma, L | 1 |
| Kandpal, G | 1 |
| Chen, E | 1 |
| Li, YM | 1 |
| Austin, CP | 1 |
| Pratt, CB | 1 |
| Wang, JJ | 1 |
| Luce, JK | 1 |
| Bodey, GP | 1 |
1 trial available for carbamates and Neuroblastoma
| Article | Year |
|---|---|
Initial clinical trials with 1,1-diphenyl-2-propynyl cyclohexanecarbamate (NCS-112682).
Topics: Alkynes; Antineoplastic Agents; Bone Marrow; Carbamates; Clinical Trials as Topic; Cyclohexanes; Eva | 1970 |
13 other studies available for carbamates and Neuroblastoma
| Article | Year |
|---|---|
Validation of an SH-SY5Y Cell-Based Acetylcholinesterase Inhibition Assay for Water Quality Assessment.
Topics: Acetylcholinesterase; Carbamates; Cholinesterase Inhibitors; Humans; Insecticides; Neuroblastoma; Or | 2022 |
Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells.
Topics: Carbamates; Cell Line, Tumor; Cell Movement; Down-Regulation; Forkhead Box Protein O3; Gene Expressi | 2019 |
γ-Secretase inhibitor I inhibits neuroblastoma cells, with NOTCH and the proteasome among its targets.
Topics: Amyloid Precursor Protein Secretases; Animals; Apoptosis; Brain Neoplasms; Carbamates; Cell Cycle; C | 2016 |
Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growth.
Topics: Antineoplastic Agents; Arachidonic Acids; Benzodioxoles; Cannabinoid Receptor Modulators; Carbamates | 2012 |
Dopamine induces apoptosis in APPswe-expressing Neuro2A cells following Pepstatin-sensitive proteolysis of APP in acid compartments.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals | 2012 |
An adjustable release rate linking strategy for cytotoxin-peptide conjugates.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Bibenzyls; Camptothecin; Carbamates; Cross-Link | 2003 |
Characterization of the effect of ganstigmine (CHF2819) on amyloid precursor protein metabolism in SH-SY5Y neuroblastoma cells.
Topics: Acetylcholine; Acetylcholinesterase; Alkaloids; Amyloid beta-Protein Precursor; Brain; Carbamates; C | 2003 |
Presenilin attenuates receptor-mediated signaling and synaptic function.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Carbazoles; | 2005 |
A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid-beta oligomeric complexes.
Topics: Amyloid beta-Peptides; Carbamates; Cell Count; Cell Death; Cell Line, Tumor; Dipeptides; Dose-Respon | 2006 |
Cytochalasin separates microtubule disassembly from loss of asymmetric morphology.
Topics: Actins; Animals; Antineoplastic Agents; Benzimidazoles; Carbamates; Cell Line; Colchicine; Cytochala | 1981 |
Neuroblastoma cells recapitulate their detailed neurite morphologies after reversible microtubule disassembly.
Topics: Benzimidazoles; Carbamates; Cell Line; Cell Movement; Microtubules; Neuroblastoma; Neurons; Nocodazo | 1980 |
Presenilin-dependent gamma-secretase activity modulates neurite outgrowth.
Topics: Adaptor Proteins, Signal Transducing; Adult; Alzheimer Disease; Amyloid Precursor Protein Secretases | 2002 |
Acetylenic carbamate in childhood cancer.
Topics: Acute Disease; Adolescent; Age Factors; Alkynes; Blood Cell Count; Bone Neoplasms; Carbamates; Child | 1971 |