Compounds > 1,2-dilinoleoyl-3-phosphatidylethanolamine
Page last updated: 2024-12-11
1,2-dilinoleoyl-3-phosphatidylethanolamine
It seems you've made a slight mix-up in the name. There's no compound called 1,2-dilinoleoyl-3-phosphatidylethanolamine.
The most likely thing you're referring to is **1,2-dilinoleoyl-sn-glycero-3-phosphoethanolamine** (also known as **DLiPE** or **18:2/18:2 PE**).
Here's why this compound is important in research:
**1. It's a common phospholipid:** DLiPE is a type of phospholipid, a class of lipids found in all cell membranes. It plays a critical role in maintaining membrane structure and fluidity.
**2. It's involved in cell signaling:** DLiPE is not just a structural component; it's also involved in cell signaling pathways. Specifically, it's a precursor for the production of **phosphatidic acid (PA)**, a key signaling molecule involved in various cellular processes such as cell growth, differentiation, and apoptosis.
**3. It's a target for research:** The involvement of DLiPE in cell signaling makes it an interesting target for research in areas like:
* **Cancer:** DLiPE is implicated in cancer cell proliferation and survival. Understanding its role in cancer cells could lead to new therapeutic targets.
* **Inflammation:** DLiPE is involved in inflammatory responses. Studying its function could lead to the development of anti-inflammatory drugs.
* **Neurological diseases:** DLiPE is found in high concentrations in the brain and may play a role in neurological disorders. Research on DLiPE could provide insights into these diseases.
**4. It's a tool for studying membrane dynamics:** Due to its specific properties, DLiPE is often used as a model system for studying membrane fluidity, phase transitions, and lipid interactions.
**In summary:** 1,2-dilinoleoyl-sn-glycero-3-phosphoethanolamine (DLiPE) is an important phospholipid involved in cell signaling, membrane structure, and various biological processes. This makes it a significant target for research in diverse fields like cancer, inflammation, and neurological diseases.
Cross-References
ID Source | ID |
PubMed CID | 6443215 |
MeSH ID | M0115086 |
Synonyms (8)
Synonym |
dilinoleoylphosphatidylethanolamine |
dilinoleoyl-pe |
dilinoleoylcephalin |
dlpe-linoleoyl |
55252-82-9 |
9,12-octadecadienoic acid (z,z)-, 1-((((2-aminoethoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl ester |
[3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-[(9e,12e)-octadeca-9,12-dienoyl]oxypropyl] (9e,12e)-octadeca-9,12-dienoate |
1,2-dilinoleoyl-3-phosphatidylethanolamine |
Research
Studies (12)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 1 (8.33) | 18.7374 |
1990's | 8 (66.67) | 18.2507 |
2000's | 2 (16.67) | 29.6817 |
2010's | 1 (8.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.61
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.61 (24.57) | Research Supply Index | 2.56 (2.92) | Research Growth Index | 5.17 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 12 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |