Page last updated: 2024-12-11

1,2-dilinoleoyl-3-phosphatidylethanolamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

It seems you've made a slight mix-up in the name. There's no compound called 1,2-dilinoleoyl-3-phosphatidylethanolamine.

The most likely thing you're referring to is **1,2-dilinoleoyl-sn-glycero-3-phosphoethanolamine** (also known as **DLiPE** or **18:2/18:2 PE**).

Here's why this compound is important in research:

**1. It's a common phospholipid:** DLiPE is a type of phospholipid, a class of lipids found in all cell membranes. It plays a critical role in maintaining membrane structure and fluidity.

**2. It's involved in cell signaling:** DLiPE is not just a structural component; it's also involved in cell signaling pathways. Specifically, it's a precursor for the production of **phosphatidic acid (PA)**, a key signaling molecule involved in various cellular processes such as cell growth, differentiation, and apoptosis.

**3. It's a target for research:** The involvement of DLiPE in cell signaling makes it an interesting target for research in areas like:

* **Cancer:** DLiPE is implicated in cancer cell proliferation and survival. Understanding its role in cancer cells could lead to new therapeutic targets.
* **Inflammation:** DLiPE is involved in inflammatory responses. Studying its function could lead to the development of anti-inflammatory drugs.
* **Neurological diseases:** DLiPE is found in high concentrations in the brain and may play a role in neurological disorders. Research on DLiPE could provide insights into these diseases.

**4. It's a tool for studying membrane dynamics:** Due to its specific properties, DLiPE is often used as a model system for studying membrane fluidity, phase transitions, and lipid interactions.

**In summary:** 1,2-dilinoleoyl-sn-glycero-3-phosphoethanolamine (DLiPE) is an important phospholipid involved in cell signaling, membrane structure, and various biological processes. This makes it a significant target for research in diverse fields like cancer, inflammation, and neurological diseases.

Cross-References

ID SourceID
PubMed CID6443215
MeSH IDM0115086

Synonyms (8)

Synonym
dilinoleoylphosphatidylethanolamine
dilinoleoyl-pe
dilinoleoylcephalin
dlpe-linoleoyl
55252-82-9
9,12-octadecadienoic acid (z,z)-, 1-((((2-aminoethoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl ester
[3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-[(9e,12e)-octadeca-9,12-dienoyl]oxypropyl] (9e,12e)-octadeca-9,12-dienoate
1,2-dilinoleoyl-3-phosphatidylethanolamine
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (8.33)18.7374
1990's8 (66.67)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.61

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.61 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index5.17 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.61)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]