quinolinic acid has been researched along with Neuroblastoma in 5 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Excerpt | Relevance | Reference |
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"Urolithin B and auraptene have been reported to exert potent antioxidant effects - however, little is known about the protective effects of these compounds against QA-induced neurotoxicity." | 5.91 | The Effects of Urolithin B and Auraptene on Quinolinic Acid-induced Toxicity in the SH-SY5Y Neuroblastoma Cell Line. ( Abbasinezhad-Moud, F; Afshari, AR; Azadi, N; Forouzanfar, F; Jalili-Nik, M; Mirzavi, F; Mohebbati, R; Rakhshandeh, H; Sanati, M; Soukhtanloo, M, 2023) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 1 (20.00) | 2.80 |
Authors | Studies |
---|---|
Abbasinezhad-Moud, F | 1 |
Mirzavi, F | 1 |
Rakhshandeh, H | 1 |
Mohebbati, R | 1 |
Forouzanfar, F | 1 |
Jalili-Nik, M | 1 |
Azadi, N | 1 |
Sanati, M | 1 |
Afshari, AR | 1 |
Soukhtanloo, M | 1 |
Gao, SM | 1 |
Wang, L | 1 |
Shi, YX | 1 |
Ju, CX | 1 |
Zhang, F | 1 |
Li, FX | 1 |
Wszelaki, N | 1 |
Melzig, MF | 1 |
Moffett, JR | 1 |
Els, T | 1 |
Espey, MG | 1 |
Walter, SA | 1 |
Streit, WJ | 1 |
Namboodiri, MA | 1 |
Oo, TF | 1 |
Siman, R | 1 |
Burke, RE | 1 |
5 other studies available for quinolinic acid and Neuroblastoma
Article | Year |
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The Effects of Urolithin B and Auraptene on Quinolinic Acid-induced Toxicity in the SH-SY5Y Neuroblastoma Cell Line.
Topics: Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Humans; Neuroblastoma; Oxidative Stress; Q | 2023 |
[Protective effects of total epimedium flavonoids against QA-induced toxicity in SH-SY5Y cells].
Topics: Antioxidants; Apoptosis; Calcium; Cell Line, Tumor; Cell Survival; Epimedium; Flavonoids; Flow Cytom | 2013 |
Research on an in vitro cell system for testing the neurotoxicity of kynurenine pathway metabolites.
Topics: Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Survival; Coloring Agents; Fluorescent | 2011 |
Quinolinate immunoreactivity in experimental rat brain tumors is present in macrophages but not in astrocytes.
Topics: Animals; Antibody Specificity; Astrocytes; Biomarkers; Brain Neoplasms; Corpus Striatum; Female; Gli | 1997 |
Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra.
Topics: Actins; Animals; Antibody Specificity; Apoptosis; Caspases; Cell Compartmentation; Cell Nucleus; Cyt | 2002 |