Page last updated: 2024-10-30

mechlorethamine and Neuroblastoma

mechlorethamine has been researched along with Neuroblastoma in 14 studies

nitrogen mustard : Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199011 (78.57)18.7374
1990's1 (7.14)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mullah-Ali, A1
Ramsay, JA1
Bourgeois, JM1
Hodson, I1
Macdonald, P1
Midia, M1
Portwine, C1
LUHBY, AL1
DIAMOND, LK1
GRISWOLD, JD1
RATNER, IA1
THURMAN, WG1
FERNBACH, DJ1
SULLIVAN, MP1
Rosen, EM1
Cassady, JR1
Frantz, CN1
Kretschmar, C1
Levey, R1
Vawter, G1
Sallan, SE1
Kushner, BH1
LaQuaglia, MP1
Cheung, NK1
Kisby, GE1
Springer, N1
Spencer, PS1
Mutz, ID1
Urban, CE1
Phillips, RF1
Posener, LJ1
Pow, CG1
Jain, KK1
Bau, S1
Lawhorn, TI1
Stone, HH1
Martin, JD1
Finklestein, JZ1
Ekert, H1
Isaacs, H1
Higgins, G1
Sinks, LF1
Woodruff, MW1

Reviews

2 reviews available for mechlorethamine and Neuroblastoma

ArticleYear
Paraspinal synovial sarcoma as an unusual postradiation complication in pediatric abdominal neuroblastoma.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 18; Chromosomes, Human, X;

2008
Chemotherapy in solid tumors of childhood.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Abdominal Neoplasms; Adolescent; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Eye Neopla

1972

Other Studies

12 other studies available for mechlorethamine and Neuroblastoma

ArticleYear
Neuroblastoma metastases; diagnosis by bone marrow aspiration, with note on therapy with radioactive phosphorus and nitrogen mustard.
    Proceedings. American Federation for Clinical Research, 1947, Volume: 3

    Topics: Bone Marrow; Humans; Mechlorethamine; Neoplasm Metastasis; Neuroblastoma; Phosphorus; Radioactivity;

1947
NEUROBLASTOMA IN INFANCY AND CHILDHOOD.
    The Medical annals of the District of Columbia, 1964, Volume: 33

    Topics: Adrenal Gland Neoplasms; Antineoplastic Agents; Bone Neoplasms; Child; Humans; Infant; Lymphatic Met

1964
NEUROBLASTOMA AND WILMS'S TUMOR IN INFANTS AND CHILDREN.
    Texas state journal of medicine, 1964, Volume: 60

    Topics: Adolescent; Child; Cyclophosphamide; Humans; Infant; Mechlorethamine; Methotrexate; Muscle Proteins;

1964
CYCLOPHOSPHAMIDE THERAPY IN CHILDHOOD NEUROBLASTOMA.
    The New England journal of medicine, 1964, Jun-18, Volume: 270

    Topics: Child; Cyclophosphamide; Dactinomycin; Humans; Infant; Mechlorethamine; Methotrexate; Neoplasm Metas

1964
Improved survival in neuroblastoma using multimodality therapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1984, Volume: 2, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Comb

1984
Rethinking management of localized neuroblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cisplatin; Combined Modality Therapy; Cycloph

1993
In vitro neurotoxic and DNA-damaging properties of nitrogen mustard.
    Journal of applied toxicology : JAT, 2000, Volume: 20 Suppl 1

    Topics: Animals; Astrocytes; Central Nervous System; Cerebellum; Dermatologic Agents; DNA Adducts; DNA Damag

2000
[Dimethyl-triazeno-imidazole-carboxamide (DTIC) in combination chemotherapy for childhood neuroblastoma (author's transl)].
    Wiener klinische Wochenschrift, 1978, Dec-22, Volume: 90, Issue:24

    Topics: Child, Preschool; Dacarbazine; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Huma

1978
Cyclophosphamide and the pubertal testis.
    Lancet (London, England), 1973, Feb-17, Volume: 1, Issue:7799

    Topics: Abortion, Therapeutic; Adolescent; Child; Child, Preschool; Female; Humans; Infant; Mechlorethamine;

1973
Life threatening disease. An unusual case of severe burns, meningitis, obstructive hydrocephalus and neuroblastoma in a child under age two.
    Clinical pediatrics, 1968, Volume: 7, Issue:5

    Topics: Burns; Humans; Hydrocephalus; Infant; Male; Mechlorethamine; Meningitis; Methotrexate; Neuroblastoma

1968
Bone marrow metastases in children with solid tumors.
    American journal of diseases of children (1960), 1970, Volume: 119, Issue:1

    Topics: Bone Marrow Diseases; Bone Marrow Examination; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin

1970
Chemotherapy of neuroblastoma.
    JAMA, 1968, Jul-15, Volume: 205, Issue:3

    Topics: Age Factors; Child, Preschool; Cyclophosphamide; Dactinomycin; Humans; Infant; Mechlorethamine; Neop

1968