Page last updated: 2024-10-26

racemetirosine and Neuroblastoma

racemetirosine has been researched along with Neuroblastoma in 4 studies

alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kume, T1
Kawato, Y1
Osakada, F1
Izumi, Y1
Katsuki, H1
Nakagawa, T1
Kaneko, S1
Niidome, T1
Takada-Takatori, Y1
Akaike, A1
Anton, AH1
Crumrine, RS1
Stern, RC1
Izant, RJ1
Caballero, R1
Pirmohamed, R1
Wright, JA1
Bräutigam, M1
Laschinski, G1
Kittner, B1
Herken, H1

Other Studies

4 other studies available for racemetirosine and Neuroblastoma

ArticleYear
Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype.
    Neuroscience letters, 2008, Oct-10, Volume: 443, Issue:3

    Topics: alpha-Methyltyrosine; Animals; Antineoplastic Agents; Butyrates; Carbazoles; Cell Differentiation; C

2008
Inhibition of catecholamine biosynthesis by carbidopa and metyrosine in neuroblastoma.
    Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:2

    Topics: alpha-Methyltyrosine; Carbidopa; Catecholamines; Child, Preschool; Dihydroxyphenylalanine; Dopamine;

1983
Use of alpha-methyl-tyrosine for refractory hypertension in a child with neuroblastoma.
    Critical care medicine, 1992, Volume: 20, Issue:7

    Topics: Abdominal Neoplasms; alpha-Methyltyrosine; Blood Pressure; Combined Modality Therapy; Dose-Response

1992
Effect of apomorphine, alpha-methylparatyrosine, haloperidol and reserpine on DOPA production in clonal cell lines (PC-12 and N1E-115).
    Biochemical pharmacology, 1985, Apr-01, Volume: 34, Issue:7

    Topics: Adrenal Gland Neoplasms; alpha-Methyltyrosine; Animals; Apomorphine; Cell Line; Dihydroxyphenylalani

1985