propidium has been researched along with Neuroblastoma in 17 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " A combination of Annexin V binding and propidium iodide (PI) exclusion was used to distinguish apoptosis from necrosis in flow cytometry experiments and FACS profiles of permeabilised PI-labelled cells were employed for the assessment of cell cycle distribution." | 7.73 | Isatin, an endogenous monoamine oxidase inhibitor, triggers a dose- and time-dependent switch from apoptosis to necrosis in human neuroblastoma cells. ( Glover, V; Igosheva, N; Lorz, C; Mehmet, H; O'Conner, E, 2005) |
| " These data support strict anaerobic glucose utilization in the presence of toxic levels of MPP+." | 5.32 | D-(+)-glucose rescue against 1-methyl-4-phenylpyridinium toxicity through anaerobic glycolysis in neuroblastoma cells. ( Mazzio, E; Soliman, KF, 2003) |
| " It was reported recently that nicotine may have protective effects against salsolinol-induced toxicity in human neuroblastoma derived SH-SY5Y cells and that these effects of nicotine are mediated by nicotinic receptors." | 3.75 | Additive protective effects of donepezil and nicotine against salsolinol-induced cytotoxicity in SH-SY5Y cells. ( Das, JR; Tizabi, Y, 2009) |
| " A combination of Annexin V binding and propidium iodide (PI) exclusion was used to distinguish apoptosis from necrosis in flow cytometry experiments and FACS profiles of permeabilised PI-labelled cells were employed for the assessment of cell cycle distribution." | 3.73 | Isatin, an endogenous monoamine oxidase inhibitor, triggers a dose- and time-dependent switch from apoptosis to necrosis in human neuroblastoma cells. ( Glover, V; Igosheva, N; Lorz, C; Mehmet, H; O'Conner, E, 2005) |
| "Neuroblastoma is a common pediatric malignancy that metastasizes to the liver, bone, and other organs." | 1.34 | Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells. ( Chesler, L; Gable, K; Goldenberg, DD; Goldfine, ID; Liu, D; Maddux, BA; Matthay, KK; Meyer, GE; Rosenthal, SM; Weiss, WA; Youngren, JF, 2007) |
| "Zinc was used to treat SH-SY5Y neuroblastoma cells and effects investigated in relation to PKB, p70S6K, and ERK1/2 in the absence and presence of the pro-apoptotic agent staurosporine (STS)." | 1.33 | Zinc-induced anti-apoptotic effects in SH-SY5Y neuroblastoma cells via the extracellular signal-regulated kinase 1/2. ( An, WL; Cowburn, RF; Nishimura, T; Pei, JJ; Winblad, B, 2005) |
| " These data support strict anaerobic glucose utilization in the presence of toxic levels of MPP+." | 1.32 | D-(+)-glucose rescue against 1-methyl-4-phenylpyridinium toxicity through anaerobic glycolysis in neuroblastoma cells. ( Mazzio, E; Soliman, KF, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 12 (70.59) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, J | 1 |
| Liu, B | 1 |
| Xu, Z | 1 |
| Feng, M | 1 |
| Ji, Y | 1 |
| Karbaschi, M | 1 |
| Cooke, MS | 1 |
| Hou, L | 1 |
| Ju, C | 1 |
| Zhang, J | 1 |
| Song, J | 1 |
| Ge, Y | 1 |
| Yue, W | 1 |
| Das, JR | 1 |
| Tizabi, Y | 1 |
| Di Francesco, AM | 1 |
| Ubezio, P | 1 |
| Torella, AR | 1 |
| Meco, D | 1 |
| Pierri, F | 1 |
| Barone, G | 1 |
| Cusano, G | 1 |
| Pisano, C | 1 |
| D'Incalci, M | 1 |
| Riccardi, R | 1 |
| Ferreira, M | 1 |
| Cabado, AG | 1 |
| Chapela, MJ | 1 |
| Fajardo, P | 1 |
| Atanassova, M | 1 |
| Garrido, A | 1 |
| Vieites, JM | 1 |
| Lago, J | 1 |
| Mazzio, E | 1 |
| Soliman, KF | 1 |
| Sabbatini, M | 1 |
| Bozzo, C | 1 |
| Castellucci, M | 1 |
| Cannas, M | 1 |
| An, WL | 1 |
| Pei, JJ | 1 |
| Nishimura, T | 1 |
| Winblad, B | 1 |
| Cowburn, RF | 1 |
| Igosheva, N | 1 |
| Lorz, C | 1 |
| O'Conner, E | 1 |
| Glover, V | 1 |
| Mehmet, H | 1 |
| Marco-Contelles, J | 1 |
| León, R | 1 |
| de los Ríos, C | 1 |
| García, AG | 1 |
| López, MG | 1 |
| Villarroya, M | 1 |
| Patel, D | 1 |
| Good, T | 1 |
| Meyer, GE | 1 |
| Chesler, L | 1 |
| Liu, D | 1 |
| Gable, K | 1 |
| Maddux, BA | 1 |
| Goldenberg, DD | 1 |
| Youngren, JF | 1 |
| Goldfine, ID | 1 |
| Weiss, WA | 1 |
| Matthay, KK | 1 |
| Rosenthal, SM | 1 |
| Buttiglione, M | 1 |
| Roca, L | 1 |
| Montemurno, E | 1 |
| Vitiello, F | 1 |
| Capozzi, V | 1 |
| Cibelli, G | 1 |
| Chen, L | 1 |
| Liu, L | 1 |
| Luo, Y | 1 |
| Huang, S | 1 |
| Falsig, J | 1 |
| Julius, C | 1 |
| Margalith, I | 1 |
| Schwarz, P | 1 |
| Heppner, FL | 1 |
| Aguzzi, A | 1 |
| Adler, M | 1 |
| Shafer, H | 1 |
| Hamilton, T | 1 |
| Petrali, JP | 1 |
17 other studies available for propidium and Neuroblastoma
| Article | Year |
|---|---|
Silencing of Circ_0135889 Restrains Proliferation and Tumorigenicity of Human Neuroblastoma Cells.
Topics: Annexin A5; Cell Line, Tumor; Cell Movement; Cell Proliferation; Child; Child, Preschool; Deoxyuridi | 2022 |
Mycoplasma infection of cultured cells induces oxidative stress and attenuates cellular base excision repair activity.
Topics: Cell Line, Tumor; Comet Assay; DNA Breaks; DNA Damage; DNA Glycosylases; DNA Repair; Guanine; Humans | 2019 |
Antitumor effects of Isatin on human neuroblastoma cell line (SH-SY5Y) and the related mechanism.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Benzimidazoles; Blotting, Western; Cas | 2008 |
Additive protective effects of donepezil and nicotine against salsolinol-induced cytotoxicity in SH-SY5Y cells.
Topics: Analysis of Variance; Annexin A5; Apoptosis; Atropine; Cell Cycle; Cell Line, Tumor; Cell Survival; | 2009 |
Enhanced cell cycle perturbation and apoptosis mediate the synergistic effects of ST1926 and ATRA in neuroblastoma preclinical models.
Topics: Adamantane; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Blotting, Western; Bromodeoxyuridin | 2012 |
Cytotoxic activity of extracts of marine sponges from NW Spain on a neuroblastoma cell line.
Topics: Animals; Antineoplastic Agents; Aquatic Organisms; Cell Line, Tumor; Cell Membrane; Cell Proliferati | 2011 |
D-(+)-glucose rescue against 1-methyl-4-phenylpyridinium toxicity through anaerobic glycolysis in neuroblastoma cells.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Anaerobiosis; Animals; Cell Death; Cell Surviva | 2003 |
Morphometric quantification of apoptotic stages in cell culture.
Topics: Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Adhesion; Cell Line, Tumor; Cell Nucleus; Co | 2004 |
Zinc-induced anti-apoptotic effects in SH-SY5Y neuroblastoma cells via the extracellular signal-regulated kinase 1/2.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Size; Cell Survival; DNA Fragmentation; Dose-Re | 2005 |
Isatin, an endogenous monoamine oxidase inhibitor, triggers a dose- and time-dependent switch from apoptosis to necrosis in human neuroblastoma cells.
Topics: Annexin A5; Antiparkinson Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Membrane Permeabilit | 2005 |
New multipotent tetracyclic tacrines with neuroprotective activity.
Topics: Acetylcholinesterase; Calcium; Cholinesterase Inhibitors; Cytosol; Humans; L-Lactate Dehydrogenase; | 2006 |
A rapid method to measure beta-amyloid induced neurotoxicity in vitro.
Topics: Amyloid beta-Peptides; Analysis of Variance; Apoptosis; Cell Line, Tumor; Cell Survival; Dactinomyci | 2007 |
Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells.
Topics: Animals; Apoptosis; Caspase 3; Cell Culture Techniques; Cell Movement; Cell Proliferation; Cell Surv | 2007 |
Radiofrequency radiation (900 MHz) induces Egr-1 gene expression and affects cell-cycle control in human neuroblastoma cells.
Topics: Apoptosis; Blotting, Western; Cell Culture Techniques; Cell Cycle; Cell Line, Tumor; Cell Survival; | 2007 |
MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis.
Topics: Animals; Apoptosis; Cadmium; Cell Differentiation; Cell Line; Enzyme Inhibitors; Humans; Mitogen-Act | 2008 |
A versatile prion replication assay in organotypic brain slices.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Caspase 3; CD11b Antigen; Cell Death; Ce | 2008 |
Cytotoxic actions of the heavy metal chelator TPEN on NG108-15 neuroblastoma-glioma cells.
Topics: Animals; Apoptosis; Biomarkers; Cell Aggregation; Cell Nucleus; Cell Survival; Chelating Agents; Chr | 1999 |