pteridines has been researched along with Neuroblastoma in 14 studies
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we analyze in vitro the antiproliferative efficacy, apoptotic properties and effects of three new disilver complexes containing E-6-(hydroxyimino)ethyl-1,3,7-trimethyllumazine (lumazine=pteridine-2,4(1H,3H)-dione) on RAS-regulating APA and APN specific activities in human neuroblastoma and glioma cell lines NB69 and U373-MG." | 7.80 | Silver(I)/6-hydroxyiminolumazine compounds differently modify renin-angiotensin system-regulating aminopeptidases A and N in human neuroblastoma and glioma cells. ( Carrera-González, MP; Hueso-Ureña, F; Illán-Cabeza, NA; Jiménez-Pulido, SB; Martínez-Martos, JM; Mayas-Torres, MD; Moreno-Carretero, MN; Ramírez-Expósito, MJ; Sánchez-Sánchez, P, 2014) |
| "The IMP dehydrogenase inhibitor, tiazofurin (TR)-2-beta-D-ribofuranosylthiazole-4-carboxamide, which exhibited oncolytic activity in patients with chronic myelogenous leukaemia (CML) in blast crisis was found to inhibit the growth of human neuroblastoma SK-N-SH cells with an IC50 of 4." | 7.68 | Cytotoxicity, differentiating activity and metabolism of tiazofurin in human neuroblastoma cells. ( Cermak, B; Chiba, P; Gharehbaghi, K; Jayaram, HN; Knoflach, A; Pillwein, K; Ressmańn, G; Schuchter, K; Szalay, SM; Szekeres, T, 1993) |
| "These findings support the further exploration of volasertib for pediatric malignancies, particularly alveolar rhabdomyosarcoma, and its combination with mitotic spindle poison." | 3.83 | Polo-like Kinase Inhibitor Volasertib Exhibits Antitumor Activity and Synergy with Vincristine in Pediatric Malignancies. ( Abbou, S; Daudigeos-Dubus, E; Geoerger, B; Lanvers-Kaminsky, C; Laplace-Builhe, C; LE Dret, L; Molenaar, J; Vassal, G, 2016) |
| " Here we analyze in vitro the antiproliferative efficacy, apoptotic properties and effects of three new disilver complexes containing E-6-(hydroxyimino)ethyl-1,3,7-trimethyllumazine (lumazine=pteridine-2,4(1H,3H)-dione) on RAS-regulating APA and APN specific activities in human neuroblastoma and glioma cell lines NB69 and U373-MG." | 3.80 | Silver(I)/6-hydroxyiminolumazine compounds differently modify renin-angiotensin system-regulating aminopeptidases A and N in human neuroblastoma and glioma cells. ( Carrera-González, MP; Hueso-Ureña, F; Illán-Cabeza, NA; Jiménez-Pulido, SB; Martínez-Martos, JM; Mayas-Torres, MD; Moreno-Carretero, MN; Ramírez-Expósito, MJ; Sánchez-Sánchez, P, 2014) |
| "The effect of cyclic nucleotide phosphodiesterase (PDE) inhibitors Zaprinast and DC-TA-46 has been tested on SK-N-MC neuroblastoma growth." | 3.71 | In vitro and in vivo inhibition of SK-N-MC neuroblastoma growth using cyclic nucleotide phosphodiesterase inhibitors. ( Augusti-Tocco, G; Citro, G; Giorgi, M; Leonetti, C, 2001) |
| "The IMP dehydrogenase inhibitor, tiazofurin (TR)-2-beta-D-ribofuranosylthiazole-4-carboxamide, which exhibited oncolytic activity in patients with chronic myelogenous leukaemia (CML) in blast crisis was found to inhibit the growth of human neuroblastoma SK-N-SH cells with an IC50 of 4." | 3.68 | Cytotoxicity, differentiating activity and metabolism of tiazofurin in human neuroblastoma cells. ( Cermak, B; Chiba, P; Gharehbaghi, K; Jayaram, HN; Knoflach, A; Pillwein, K; Ressmańn, G; Schuchter, K; Szalay, SM; Szekeres, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramírez-Expósito, MJ | 2 |
| Mayas-Torres, MD | 1 |
| Carrera-González, MP | 1 |
| Jiménez-Pulido, SB | 2 |
| Illán-Cabeza, NA | 1 |
| Sánchez-Sánchez, P | 1 |
| Hueso-Ureña, F | 1 |
| Martínez-Martos, JM | 2 |
| Moreno-Carretero, MN | 2 |
| Abbou, S | 1 |
| Lanvers-Kaminsky, C | 1 |
| Daudigeos-Dubus, E | 1 |
| LE Dret, L | 1 |
| Laplace-Builhe, C | 1 |
| Molenaar, J | 1 |
| Vassal, G | 1 |
| Geoerger, B | 1 |
| Xiao, D | 1 |
| Yue, M | 1 |
| Su, H | 1 |
| Ren, P | 1 |
| Jiang, J | 1 |
| Li, F | 1 |
| Hu, Y | 1 |
| Du, H | 1 |
| Liu, H | 1 |
| Qing, G | 1 |
| Linares-Ordóñez, FM | 1 |
| Quirós-Olozábal, M | 1 |
| Ackermann, S | 1 |
| Goeser, F | 1 |
| Schulte, JH | 1 |
| Schramm, A | 1 |
| Ehemann, V | 1 |
| Hero, B | 1 |
| Eggert, A | 1 |
| Berthold, F | 1 |
| Fischer, M | 1 |
| Grinshtein, N | 1 |
| Datti, A | 1 |
| Fujitani, M | 1 |
| Uehling, D | 1 |
| Prakesch, M | 1 |
| Isaac, M | 1 |
| Irwin, MS | 1 |
| Wrana, JL | 1 |
| Al-Awar, R | 1 |
| Kaplan, DR | 1 |
| Bräutigam, M | 1 |
| Dreesen, R | 1 |
| Herken, H | 1 |
| Duch, DS | 2 |
| Lee, CL | 1 |
| Edelstein, MP | 1 |
| Nichol, CA | 2 |
| Woolf, JH | 1 |
| Pillwein, K | 1 |
| Schuchter, K | 1 |
| Ressmańn, G | 1 |
| Gharehbaghi, K | 1 |
| Knoflach, A | 1 |
| Cermak, B | 1 |
| Jayaram, HN | 1 |
| Szalay, SM | 1 |
| Szekeres, T | 1 |
| Chiba, P | 1 |
| Giorgi, M | 1 |
| Leonetti, C | 1 |
| Citro, G | 1 |
| Augusti-Tocco, G | 1 |
| Albrecht, AM | 1 |
| Biedler, JL | 1 |
| Baker, H | 1 |
| Frank, O | 1 |
| Hutner, SH | 1 |
| Fukushima, T | 1 |
| Shiota, T | 1 |
| Imashuku, S | 1 |
| Labrosse, EH | 1 |
| Johnson, EM | 1 |
| Morgenroth, VH | 1 |
| Zenker, N | 1 |
14 other studies available for pteridines and Neuroblastoma
| Article | Year |
|---|---|
Silver(I)/6-hydroxyiminolumazine compounds differently modify renin-angiotensin system-regulating aminopeptidases A and N in human neuroblastoma and glioma cells.
Topics: Antineoplastic Agents; Apoptosis; CD13 Antigens; Cell Line, Tumor; Glioma; Glutamyl Aminopeptidase; | 2014 |
Polo-like Kinase Inhibitor Volasertib Exhibits Antitumor Activity and Synergy with Vincristine in Pediatric Malignancies.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Bone Neoplasm | 2016 |
Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle | 2016 |
Metal complexes with the ligand derived from 6-acetyl-1,3,7-trimethyllumazine and benzohydrazide. Molecular structures of two new Co(II) and Rh(III) complexes and analysis of in vitro antitumor activity.
Topics: Antineoplastic Agents; Azides; Cell Line, Tumor; Cobalt; Crystallography, X-Ray; Drug Screening Assa | 2008 |
Polo-like kinase 1 is a therapeutic target in high-risk neuroblastoma.
Topics: Adolescent; Animals; Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferatio | 2011 |
Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells.
Topics: Algorithms; Animals; Brain Neoplasms; Cell Cycle Proteins; Cells, Cultured; High-Throughput Screenin | 2011 |
Tetrahydrobiopterin and total biopterin content of neuroblastoma (N1E-115, N2A) and pheochromocytoma (PC-12) clones and the dependence of catecholamine synthesis on tetrahydrobiopterin concentration in PC-12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Biopterins; Catecholamines; Cell Line; Chromatography, High Pressu | 1984 |
Biosynthesis of tetrahydrobiopterin in the presence of dihydrofolate reductase inhibitors.
Topics: Animals; Biopterins; Cell Line; Clone Cells; Folic Acid Antagonists; GTP Cyclohydrolase; Guanosine T | 1983 |
Determination of biopterin and other pterins in tissues and body fluids by high-performance liquid chromatography.
Topics: Biopterins; Body Fluids; Chromatography, High Pressure Liquid; Humans; Neopterin; Neuroblastoma; Pte | 1983 |
Cytotoxicity, differentiating activity and metabolism of tiazofurin in human neuroblastoma cells.
Topics: Antimetabolites, Antineoplastic; Catecholamines; Cell Differentiation; Cell Survival; Child, Prescho | 1993 |
In vitro and in vivo inhibition of SK-N-MC neuroblastoma growth using cyclic nucleotide phosphodiesterase inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antineoplastic Agents; Cell Division; Male; Mice; Mice | 2001 |
Biopterin content of human neuroblastoma cells in culture.
Topics: Biopterins; Cells, Cultured; Humans; Neuroblastoma; Pteridines | 1978 |
Biosynthesis of biopterin by Chinese hamster ovary (CHO K1) cell culture.
Topics: Animals; Anura; Biological Assay; Carbon Radioisotopes; Cell Line; Chromatography, Gel; Chromatograp | 1974 |
Tyrosine hydroxylase in neuroblastoma.
Topics: Adrenal Glands; Alanine; Animals; Benzimidazoles; Cattle; Child, Preschool; Dihydroxyphenylalanine; | 1971 |