nickel has been researched along with Neuroblastoma in 23 studies
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
nickel ion : A nickel atom having a net electric charge.
nickel atom : Chemical element (nickel group element atom) with atomic number 28.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to approach the molecular mechanism of Li+'s mood-stabilizing action, the effect of Li+ (LiCl) on inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] mass was investigated in human neuroblastoma SH-SY5Y cells, which express muscarinic M3 receptors, coupled to PtdIns hydrolysis." | 7.69 | Time-dependent effects of lithium on the agonist-stimulated accumulation of second messenger inositol 1,4,5-trisphosphate in SH-SY5Y human neuroblastoma cells. ( Artemenko, IP; Hokin, LE; Los, GV, 1995) |
| "Bradykinin (BK) evoked [3H]noradrenaline ([3H]NA) release from the human neuroblastoma SH-SY5Y and this was enhanced by pre-treatment with 12-O-tetradecanoylphorbol 13-acetate (TPA) for 8 min." | 7.69 | Bradykinin-evoked release of [3H]noradrenaline from the human neuroblastoma SH-SY5Y. ( Ball, SG; Kaye, DF; McDonald, RL; Peers, C; Reeve, HL; Vaughan, PF, 1994) |
| "Stimulation of neuropeptide Y (NPY) Y2 receptors induced an intracellular free Ca2+ ([Ca2+]i) increase in a human neuroblastoma cell line, CHP-234." | 7.69 | A pertussis toxin-insensitive calcium influx mediated by neuropeptide Y2 receptors in a human neuroblastoma cell line. ( Bucher, B; Lemos, VS; Lynch, JW; Stoclet, JC; Takeda, K, 1994) |
| "Stimulation of muscarinic receptors expressed in SH-SY5Y human neuroblastoma cells resulted in a complex profile of inositol 1,4,5-trisphosphate (InsP3) accumulation, with a dramatic increase (six- to eightfold) over the first 10 s (the "peak" phase) and subsequently from approximately 60 s onward, maintained at a lower but sustained level (the "plateau" phase)." | 7.69 | Muscarinic receptor-mediated inositol 1,4,5-trisphosphate formation in SH-SY5Y neuroblastoma cells is regulated acutely by cytosolic Ca2+ and by rapid desensitization. ( Nahorski, SR; Tobin, AB; Wojcikiewicz, RJ, 1994) |
| "In order to approach the molecular mechanism of Li+'s mood-stabilizing action, the effect of Li+ (LiCl) on inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] mass was investigated in human neuroblastoma SH-SY5Y cells, which express muscarinic M3 receptors, coupled to PtdIns hydrolysis." | 3.69 | Time-dependent effects of lithium on the agonist-stimulated accumulation of second messenger inositol 1,4,5-trisphosphate in SH-SY5Y human neuroblastoma cells. ( Artemenko, IP; Hokin, LE; Los, GV, 1995) |
| "The effects of bepridil and benzamil, known Na(+)-Ca2+ exchange blockers, on the growth of human brain tumor cells were evaluated using SK-N-MC human neuroblastoma and U-373 MG human astrocytoma cells as model cellular systems." | 3.69 | Intracellular Ca2+ mediates the cytotoxicity induced by bepridil and benzamil in human brain tumor cells. ( Lee, YS; Sayeed, MM; Wurster, RD, 1995) |
| "Bradykinin (BK) evoked [3H]noradrenaline ([3H]NA) release from the human neuroblastoma SH-SY5Y and this was enhanced by pre-treatment with 12-O-tetradecanoylphorbol 13-acetate (TPA) for 8 min." | 3.69 | Bradykinin-evoked release of [3H]noradrenaline from the human neuroblastoma SH-SY5Y. ( Ball, SG; Kaye, DF; McDonald, RL; Peers, C; Reeve, HL; Vaughan, PF, 1994) |
| "Stimulation of neuropeptide Y (NPY) Y2 receptors induced an intracellular free Ca2+ ([Ca2+]i) increase in a human neuroblastoma cell line, CHP-234." | 3.69 | A pertussis toxin-insensitive calcium influx mediated by neuropeptide Y2 receptors in a human neuroblastoma cell line. ( Bucher, B; Lemos, VS; Lynch, JW; Stoclet, JC; Takeda, K, 1994) |
| "Stimulation of muscarinic receptors expressed in SH-SY5Y human neuroblastoma cells resulted in a complex profile of inositol 1,4,5-trisphosphate (InsP3) accumulation, with a dramatic increase (six- to eightfold) over the first 10 s (the "peak" phase) and subsequently from approximately 60 s onward, maintained at a lower but sustained level (the "plateau" phase)." | 3.69 | Muscarinic receptor-mediated inositol 1,4,5-trisphosphate formation in SH-SY5Y neuroblastoma cells is regulated acutely by cytosolic Ca2+ and by rapid desensitization. ( Nahorski, SR; Tobin, AB; Wojcikiewicz, RJ, 1994) |
| "Lithium has a biphasic effect of the agonist-dependent accumulation of Ins(1,4,5)P3 in human neuroblastoma SH-SY5Y cells." | 3.69 | Phosphoinositide signalling in human neuroblastoma cells: biphasic effect of Li+ on the level of the inositolphosphate second messengers. ( Artemenko, IP; Hokin, LE; Los, GV, 1996) |
| "Several calcium antagonists were screened for their effect on muscarinic acetylcholine receptor-mediated cyclic GMP formation in murine neuroblastoma cells (clone N1E-115)." | 3.66 | Effect of some calcium antagonists on muscarinic receptor-mediated cyclic GMP formation. ( El-Fakahany, E; Richelson, E, 1983) |
| " This close temporal and dose-response relationship strongly suggests that delta-opioid receptor-mediated increases in intracellular [Ca2+] results from inositol 1,4,5-trisphosphate-induced Ca2+ release from intracellular stores, in undifferentiated NG108-15 cells." | 1.29 | delta-Opioids stimulate inositol 1,4,5-trisphosphate formation, and so mobilize Ca2+ from intracellular stores, in undifferentiated NG108-15 cells. ( Lambert, DG; Smart, D, 1996) |
| "Carbachol-stimulated increase in [Ca2+]i was blocked by atropine and Ni2+ but was totally resistant to the L- and N-channel blockers." | 1.28 | Different mechanisms of Ca2+ entry induced by depolarization and muscarinic receptor stimulation in SH-SY5Y human neuroblastoma cells. ( Baird, JG; Lambert, DG; Nahorski, SR; Whitham, EM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 17 (73.91) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Covy, JP | 1 |
| Waxman, EA | 1 |
| Giasson, BI | 1 |
| Higashide, S | 1 |
| Morikawa, K | 1 |
| Okumura, M | 1 |
| Kondo, S | 1 |
| Ogata, M | 1 |
| Murakami, T | 1 |
| Yamashita, A | 1 |
| Kanemoto, S | 1 |
| Manabe, T | 1 |
| Imaizumi, K | 1 |
| Chevalier, M | 1 |
| Lory, P | 1 |
| Mironneau, C | 1 |
| Macrez, N | 1 |
| Quignard, JF | 1 |
| Cagide, E | 1 |
| Louzao, MC | 1 |
| Ares, IR | 1 |
| Vieytes, MR | 1 |
| Yotsu-Yamashita, M | 1 |
| Paquette, LA | 1 |
| Yasumoto, T | 1 |
| Botana, LM | 1 |
| El-Fakahany, E | 1 |
| Richelson, E | 1 |
| Kondo, K | 1 |
| Ozaki, T | 1 |
| Nakamura, Y | 1 |
| Sakiyama, S | 1 |
| Carlson, RO | 1 |
| Masco, D | 1 |
| Brooker, G | 1 |
| Spiegel, S | 1 |
| Los, GV | 2 |
| Artemenko, IP | 2 |
| Hokin, LE | 2 |
| Kito, M | 1 |
| Maehara, M | 1 |
| Watanabe, K | 1 |
| Basavappa, S | 1 |
| Chartouni, V | 1 |
| Kirk, K | 1 |
| Prpic, V | 1 |
| Ellory, JC | 1 |
| Mangel, AW | 1 |
| Lee, YS | 1 |
| Sayeed, MM | 1 |
| Wurster, RD | 1 |
| McDonald, RL | 1 |
| Kaye, DF | 1 |
| Reeve, HL | 1 |
| Ball, SG | 1 |
| Peers, C | 1 |
| Vaughan, PF | 1 |
| Hirst, RA | 1 |
| Lambert, DG | 3 |
| Lynch, JW | 1 |
| Lemos, VS | 1 |
| Bucher, B | 1 |
| Stoclet, JC | 1 |
| Takeda, K | 1 |
| Wojcikiewicz, RJ | 1 |
| Tobin, AB | 1 |
| Nahorski, SR | 2 |
| Hare, MF | 1 |
| Atchison, WD | 1 |
| Smart, D | 1 |
| McGinnis, KM | 1 |
| Shariat-Madar, Z | 1 |
| Gnegy, ME | 1 |
| Kopper, KL | 1 |
| Adorante, JS | 1 |
| Carbone, E | 1 |
| Sher, E | 1 |
| Clementi, F | 1 |
| Whitham, EM | 1 |
| Baird, JG | 1 |
| Eckert, R | 1 |
| Hescheler, J | 1 |
| Krautwurst, D | 1 |
| Schultz, G | 1 |
| Trautwein, W | 1 |
23 other studies available for nickel and Neuroblastoma
| Article | Year |
|---|---|
Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants.
Topics: Apoptosis; Cell Line, Tumor; Chlorides; Glutathione; HEK293 Cells; Humans; Lysosomes; Manganese Comp | 2012 |
Identification of regulatory cis-acting elements for alternative splicing of presenilin 2 exon 5 under hypoxic stress conditions.
Topics: Alternative Splicing; Alzheimer Disease; Brain; Cell Line, Tumor; Dose-Response Relationship, Drug; | 2004 |
T-type CaV3.3 calcium channels produce spontaneous low-threshold action potentials and intracellular calcium oscillations.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Calcium Sig | 2006 |
Effects of a synthetic analog of polycavernoside A on human neuroblastoma cells.
Topics: Actins; Calcium; Calcium Channel Blockers; Cell Line, Tumor; Cytosol; Disaccharides; Drug Interactio | 2007 |
Effect of some calcium antagonists on muscarinic receptor-mediated cyclic GMP formation.
Topics: Animals; Calcium; Carbachol; Cell Line; Cyclic GMP; Manganese; Mice; Neuroblastoma; Nickel; Quinucli | 1983 |
DAN gene product has an affinity for Ni2+.
Topics: Amino Acid Sequence; Animals; Chromatography, Affinity; Cross-Linking Reagents; Genes, Tumor Suppres | 1995 |
Endogenous ganglioside GM1 modulates L-type calcium channel activity in N18 neuroblastoma cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Time-dependent effects of lithium on the agonist-stimulated accumulation of second messenger inositol 1,4,5-trisphosphate in SH-SY5Y human neuroblastoma cells.
Topics: Acetylcholine; Atropine; Calcium; Egtazic Acid; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosph | 1995 |
Three types of voltage-dependent calcium currents in cultured human neuroblastoma cells.
Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Humans; Membrane Potentials; Mollusk Venoms; Ne | 1995 |
Swelling-induced chloride currents in neuroblastoma cells are calcium dependent.
Topics: Barium Compounds; Calcium; Calcium Channel Blockers; Cell Membrane; Chloride Channels; Chlorides; Cy | 1995 |
Intracellular Ca2+ mediates the cytotoxicity induced by bepridil and benzamil in human brain tumor cells.
Topics: Amiloride; Astrocytoma; Bepridil; Brain Neoplasms; Calcium; Cell Division; Cytoplasm; Humans; Neurob | 1995 |
Bradykinin-evoked release of [3H]noradrenaline from the human neuroblastoma SH-SY5Y.
Topics: Bradykinin; Calcium; Cobalt; Humans; Membrane Potentials; Neuroblastoma; Nickel; Nifedipine; Norepin | 1994 |
Carbachol stimulated cAMP formation in SH-SY5Y cells is dependent on both extracellular and intracellular calcium.
Topics: Adenylyl Cyclases; Analysis of Variance; Calcium; Carbachol; Cell Line; Cell Membrane; Cyclic AMP; H | 1993 |
A pertussis toxin-insensitive calcium influx mediated by neuropeptide Y2 receptors in a human neuroblastoma cell line.
Topics: Calcium; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Cyclic AMP; Fluorescent Dyes; Fu | 1994 |
Muscarinic receptor-mediated inositol 1,4,5-trisphosphate formation in SH-SY5Y neuroblastoma cells is regulated acutely by cytosolic Ca2+ and by rapid desensitization.
Topics: Calcium; Calcium Channels; Calcium-Transporting ATPases; Cytosol; Egtazic Acid; Humans; Hydrolysis; | 1994 |
Nifedipine and tetrodotoxin delay the onset of methylmercury-induced increase in [Ca2+]i in NG108-15 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
delta-Opioids stimulate inositol 1,4,5-trisphosphate formation, and so mobilize Ca2+ from intracellular stores, in undifferentiated NG108-15 cells.
Topics: Analgesics; Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enkephalin | 1996 |
Phosphoinositide signalling in human neuroblastoma cells: biphasic effect of Li+ on the level of the inositolphosphate second messengers.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Atropine; Calcium; Egtazic Acid; Enzym | 1996 |
Cytosolic calmodulin is increased in SK-N-SH human neuroblastoma cells due to release of calcium from intracellular stores.
Topics: Calcium; Calmodulin; Carbachol; Chelating Agents; Cytosol; Egtazic Acid; Extracellular Space; Humans | 1998 |
Regulation of intracellular calcium in N1E-115 neuroblastoma cells: the role of Na(+)/Ca(2+) exchange.
Topics: Animals; Brain Neoplasms; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Enzyme Inhibi | 2002 |
Ca currents in human neuroblastoma IMR32 cells: kinetics, permeability and pharmacology.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Different mechanisms of Ca2+ entry induced by depolarization and muscarinic receptor stimulation in SH-SY5Y human neuroblastoma cells.
Topics: Atropine; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cell Membrane; Humans; Isradipine | 1990 |
Calcium currents of neuroblastoma x glioma hybrid cells after cultivation with dibutyryl cyclic AMP and nickel.
Topics: Animals; Bucladesine; Calcium Channels; Colforsin; Cycloheximide; Glioma; Hybrid Cells; Isradipine; | 1990 |