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methoxyflurane and Neuroblastoma

methoxyflurane has been researched along with Neuroblastoma in 1 studies

Methoxyflurane: An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with NITROUS OXIDE to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180)
methoxyflurane : An ether in which the two groups attached to the central oxygen atom are methyl and 2,2-dichloro-1,1-difluoroethyl.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" Methoxyflurane shifted the 5-HT dose-response curve to lower 5-HT concentrations, without significantly changing the Hill coefficient or maximum response."1.29Actions of general anaesthetics on 5-HT3 receptors in N1E-115 neuroblastoma cells. ( Franks, NP; Jenkins, A; Lieb, WR, 1996)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jenkins, A1
Franks, NP1
Lieb, WR1

Other Studies

1 other study available for methoxyflurane and Neuroblastoma

ArticleYear
Actions of general anaesthetics on 5-HT3 receptors in N1E-115 neuroblastoma cells.
    British journal of pharmacology, 1996, Volume: 117, Issue:7

    Topics: Alcohols; Anesthetics, General; Animals; Methoxyflurane; Mice; Neuroblastoma; Patch-Clamp Techniques

1996