Page last updated: 2024-11-05

thioridazine and Neuroblastoma

thioridazine has been researched along with Neuroblastoma in 1 studies

Thioridazine: A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
thioridazine : A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" screen phenothiazines for cytotoxic activity in glioma, neuroblastoma, and primary mouse brain tissue; and (2)."7.72Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors. ( Dayag, M; Gil-Ad, I; Levkovitz, Y; Shtaif, B; Weizman, A; Zeldich, E, 2004)
" screen phenothiazines for cytotoxic activity in glioma, neuroblastoma, and primary mouse brain tissue; and (2)."3.72Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors. ( Dayag, M; Gil-Ad, I; Levkovitz, Y; Shtaif, B; Weizman, A; Zeldich, E, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gil-Ad, I1
Shtaif, B1
Levkovitz, Y1
Dayag, M1
Zeldich, E1
Weizman, A1

Other Studies

1 other study available for thioridazine and Neuroblastoma

ArticleYear
Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors.
    Journal of molecular neuroscience : MN, 2004, Volume: 22, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calmodulin; Caspase 3; Caspases; Cell Di

2004