Page last updated: 2024-11-13

bacoside a3

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

bacoside A3: from Bacopa monniera; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
BacopagenusA plant genus of the family Plantaginaceae. Members contain bacopaside, bacopasaponins and other dammarane type jujubogenins.[MeSH]PlantaginaceaeA plant family of order Lamiales. The Plantago genus is best known. Lesser known members include Hippuris, Littorella and Callitriche.[MeSH]

Cross-References

ID SourceID
PubMed CID91827005
CHEBI ID184025
MeSH IDM0232020

Synonyms (20)

Synonym
bacoside a3
CHEBI:184025
beta-d-glucopyranoside, (3beta,16beta,23r)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-yl o-alpha-l-arabinofuranosyl-(1-2)-o-(beta-d-glucopyranosyl-(1-3))-
3-beta-((o-beta-d-glucopyranosyl(1-3)-o-(alpha-l-arabinofuranosyl(1-2))-o-beta-d-glucopyranosyl)oxy)jujubogenin
1s862dj73f ,
unii-1s862dj73f
157408-08-7
(3beta,16beta,23r)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl o-alpha-l-arabinofuranosyl-(1-2)-o-(beta-d-glucopyranosyl-(1-3))-beta-d-glucopyranoside
bacoside a3 [usp-rs]
(3.beta.,16.beta.,17.alpha.,23r)-20-hydroxy-16,23:16,30-diepoxydammar-24-en-3-yl .alpha.-l-arabinofuranosyl-(1->2)-(.beta.-d-glucopyranosyl-(1->3))-.beta.-d-glucopyranoside
bacoside a3 (constituent of bacopa) [dsc]
bacoside a3, united states pharmacopeia (usp) reference standard
bacoside a3, analytical standard
bacoside a3(p)
HY-N5064
CS-0032257
Q27252831
MS-31734
DTXSID701318255
AKOS040760290

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" Bioavailability as well as binding of neuroprotective agents (such as bacosides) to these receptors is controlled by the Blood Brain Barrier (BBB)."( Insights Into the Molecular Aspects of Neuroprotective Bacoside A and Bacopaside I.
Baby, S; Sekhar, VC; Viswanathan, G, 2019
)
0.51

Dosage Studied

ExcerptRelevanceReference
" dosing significantly inhibited opioid withdrawal induced depression in mice."( Inhibitory effect of bacopasides on spontaneous morphine withdrawal induced depression in mice.
Abbas, G; Abbas, M; Ali, G; Ali, SM; Ashfaq, M; Rauf, K; Subhan, F, 2014
)
0.4
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
triterpenoidAny terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's8 (66.67)24.3611
2020's1 (8.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.13

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.13 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index5.19 (4.65)
Search Engine Demand Index21.17 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.13)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (15.38%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (84.62%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]