a-438079 and Neuroblastoma

a-438079 has been researched along with Neuroblastoma* in 1 studies

Other Studies

1 other study(ies) available for a-438079 and Neuroblastoma

Article	Year
Synthetic 1,4-Naphthoquinones inhibit P2X7 receptors in murine neuroblastoma cells. Bioorganic & medicinal chemistry, 2021, 02-01, Volume: 31 The P2X7 receptor (P2X7R) is an ATP-gated ion channel and potential therapeutic target for new drug development. In this study, we synthesized a series of new 1,4-naphthoquinone (1,4-NQ) derivatives and investigated their antagonistic effects against mouse P2X7R. We explored the ability of the tested substances to block ATP-induced Ca Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Chromobacterium; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Mice; Models, Molecular; Molecular Structure; Naphthoquinones; Neuroblastoma; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; Structure-Activity Relationship; Tumor Cells, Cultured	2021

Article

Year

Synthetic 1,4-Naphthoquinones inhibit P2X7 receptors in murine neuroblastoma cells.

Bioorganic & medicinal chemistry, 2021, 02-01, Volume: 31

The P2X7 receptor (P2X7R) is an ATP-gated ion channel and potential therapeutic target for new drug development. In this study, we synthesized a series of new 1,4-naphthoquinone (1,4-NQ) derivatives and investigated their antagonistic effects against mouse P2X7R. We explored the ability of the tested substances to block ATP-induced Ca

Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Chromobacterium; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Mice; Models, Molecular; Molecular Structure; Naphthoquinones; Neuroblastoma; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; Structure-Activity Relationship; Tumor Cells, Cultured

2021