sapropterin has been researched along with Neuroblastoma in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, HJ; Hwang, O; Kim, SW; Lee, SY | 1 |
| Choi, HJ; Hwang, O; Im, JH; Kim, M; Kim, SW; Lee, SG | 1 |
| Allison, TJ; Arnold, LA; Hyland, K; Pranzatelli, MR; Soori, GS; Tate, ED | 1 |
| Hillard, CJ; Kalivendi, SV; Kalyanaraman, B; Kotamraju, S; Shang, T; Zhao, H | 1 |
| Bräutigam, M; Kittner, B; Laschinski, G | 1 |
| Bräutigam, M; Dreesen, R; Herken, H | 1 |
| Duch, DS; Edelstein, MP; Lee, CL; Nichol, CA | 1 |
| Harada, T; Hatakeyama, K; Kagamiyama, H | 2 |
| Nagatsu, T; Ota, A; Umezawa, K; Yoshida, S | 1 |
| Hagino, Y; Katoh, S; Matsui, S; Nagatsu, T; Nomura, T; Ota, A; Umezawa, K; Yoshida, S | 1 |
| Mori, K; Nagatsu, T; Nakashima, A; Ota, A | 1 |
| Ichinose, H; Inagaki, H; Nagatsu, T; Ohye, T; Suzuki, T | 1 |
| Hirayama, K; Kapatos, G; Meyer, A; Shimoji, M; Swick, L | 1 |
| Cianchetti, C; di Porzio, U; Lilliu, V; Mancosu, C; Sorrentino, G; Zuddas, A | 1 |
| Carson, DJ; Dempsey, SI; Greeves, LG; Hyland, K; Leeming, RJ | 1 |
| Bräutigam, M; Herken, H; Kittner, B | 1 |
17 other study(ies) available for sapropterin and Neuroblastoma
| Article | Year |
|---|---|
Dopamine-dependent cytotoxicity of tetrahydrobiopterin: a possible mechanism for selective neurodegeneration in Parkinson's disease.
Topics: Animals; Antioxidants; Biopterins; Cell Death; Cell Line; Central Nervous System; Dopamine; Humans; Iron Chelating Agents; Lipid Peroxidation; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; NAD(P)H Dehydrogenase (Quinone); Neuroblastoma; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Proteins; Quinones; Toxicity Tests; Tyrosine 3-Monooxygenase | 2003 |
Utilization of exogenous tetrahydrobiopterin in nitric oxide synthesis in human neuroblastoma cell line.
Topics: Biopterins; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I | 2003 |
Evidence of cellular immune activation in children with opsoclonus-myoclonus: cerebrospinal fluid neopterin.
Topics: Adolescent; Biopterins; Case-Control Studies; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Immunity, Cellular; Immunotherapy; Infant; Longitudinal Studies; Male; Neopterin; Neuroblastoma; Paraneoplastic Syndromes, Nervous System | 2004 |
Sepiapterin attenuates 1-methyl-4-phenylpyridinium-induced apoptosis in neuroblastoma cells transfected with neuronal NOS: role of tetrahydrobiopterin, nitric oxide, and proteasome activation.
Topics: 1-Methyl-4-phenylpyridinium; Aconitate Hydratase; Apoptosis; Biopterins; Dimerization; Electron Transport Complex I; Enzyme Activation; Humans; Neuroblastoma; Nitric Oxide; Nitric Oxide Synthase Type I; Proteasome Endopeptidase Complex; Pterins; Superoxides; Transfection; Tumor Cells, Cultured | 2005 |
Inhibition of striatal tyrosine hydroxylase by low concentrations of apomorphine.
Topics: Animals; Apomorphine; Biopterins; Cells, Cultured; Corpus Striatum; Dihydroxyphenylalanine; In Vitro Techniques; Kinetics; Male; Neuroblastoma; Pheochromocytoma; Rats; Rats, Inbred Strains; Tyrosine 3-Monooxygenase | 1984 |
Tetrahydrobiopterin and total biopterin content of neuroblastoma (N1E-115, N2A) and pheochromocytoma (PC-12) clones and the dependence of catecholamine synthesis on tetrahydrobiopterin concentration in PC-12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Biopterins; Catecholamines; Cell Line; Chromatography, High Pressure Liquid; Kinetics; Mice; Neuroblastoma; Pheochromocytoma; Pteridines; Rats | 1984 |
Biosynthesis of tetrahydrobiopterin in the presence of dihydrofolate reductase inhibitors.
Topics: Animals; Biopterins; Cell Line; Clone Cells; Folic Acid Antagonists; GTP Cyclohydrolase; Guanosine Triphosphate; Male; Methotrexate; Neuroblastoma; Pteridines; Rats; Rats, Inbred Strains | 1983 |
Mycophenolic acid simultaneously reduces intracellular GTP and tetrahydrobiopterin levels in neuro-2A cells.
Topics: Alcohol Oxidoreductases; Animals; Biopterins; Cell Line; Dihydropteridine Reductase; GTP Cyclohydrolase; Guanosine Triphosphate; Kinetics; Mice; Mycophenolic Acid; Neuroblastoma; Phosphorus-Oxygen Lyases; Tumor Cells, Cultured | 1993 |
Dissociated release of tetrahydrobiopterin and nitric oxide by lipopolysaccharide from mouse neuroblastoma cells.
Topics: Animals; Antioxidants; Biopterins; Lipopolysaccharides; Mice; Mice, Inbred Strains; Neuroblastoma; Nitric Oxide | 1996 |
Tetrahydrobiopterin biosynthesis enhanced by lipopolysaccharide stimulation in murine neuroblastoma cell line N1E-115.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Benzoquinones; Biopterins; Dose-Response Relationship, Drug; Enzyme Inhibitors; GTP Cyclohydrolase; Hydroquinones; Lactams, Macrocyclic; Lipopolysaccharides; Mice; Neuroblastoma; Quinones; Ribonucleosides; Rifabutin; Signal Transduction; Tumor Cells, Cultured | 1996 |
Effect of lipopolysaccharide on the gene expression of the enzymes involved in tetrahydrobiopterin de novo biosynthesis in murine neuroblastoma cell line N1E-115.
Topics: Alcohol Oxidoreductases; Animals; Antioxidants; Biopterins; DNA Primers; Gene Expression Regulation; GTP Cyclohydrolase; Lipopolysaccharides; Mice; Neuroblastoma; Phosphorus-Oxygen Lyases; Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Characterization of wild-type and mutants of recombinant human GTP cyclohydrolase I: relationship to etiology of dopa-responsive dystonia.
Topics: Amino Acid Sequence; Biopterins; DNA Mutational Analysis; Dystonic Disorders; Frameshift Mutation; Gene Expression Regulation; Genes, Dominant; Genes, Recessive; GTP Cyclohydrolase; Humans; Molecular Sequence Data; Neuroblastoma; Phenylalanine; Point Mutation; Recombinant Fusion Proteins; Tumor Cells, Cultured | 1999 |
Characterization of GTP cyclohydrolase I gene expression in the human neuroblastoma SKN-BE(2)M17: enhanced transcription in response to cAMP is conferred by the proximal promoter.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Activating Transcription Factor 2; Alternative Splicing; Base Sequence; Biogenic Monoamines; Biopterins; Blotting, Northern; CCAAT-Binding Factor; Cyclic AMP Response Element-Binding Protein; DNA Footprinting; Gene Expression Regulation, Enzymologic; GTP Cyclohydrolase; Humans; Molecular Sequence Data; Neuroblastoma; Promoter Regions, Genetic; Ribonucleases; RNA, Messenger; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
6R-Tetrahydrobiopterin induces dopamine synthesis in a human neuroblastoma cell line, LA-N-1. A cellular model of DOPA-responsive dystonia.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Biopterins; Dopamine; Dopamine Antagonists; Dystonic Disorders; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Models, Biological; Monoamine Oxidase Inhibitors; Neuroblastoma; Neurons; Serotonin; Serotonin Antagonists; Substantia Nigra; Tryptophan Hydroxylase; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 2002 |
IMP dehydrogenase inhibitors reduce intracellular tetrahydrobiopterin levels through reduction of intracellular GTP levels. Indications of the regulation of GTP cyclohydrolase I activity by restriction of GTP availability in the cells.
Topics: Animals; Antineoplastic Agents; Biopterins; GTP Cyclohydrolase; Guanine; Guanosine; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Kinetics; Mycophenolic Acid; Neuroblastoma; PC12 Cells; Ribavirin; Thiadiazoles; Tumor Cells, Cultured | 1992 |
Neuroblastoma in a patient with dihydropteridine reductase deficiency.
Topics: Adrenal Gland Neoplasms; Biopterins; Catecholamines; Child; Coenzymes; Female; Humans; Neuroblastoma; Phenylalanine; Phenylketonurias; Serotonin | 1990 |
Evaluation of neurotropic drug actions on tyrosine hydroxylase activity and dopamine metabolism in clonal cell lines.
Topics: Animals; Biopterins; Catechols; Cell Line; Clone Cells; Dihydroxyphenylalanine; Dopamine; Glioma; Mice; Neuroblastoma; Neurons; Tyrosine 3-Monooxygenase | 1985 |