pentetic acid has been researched along with Neuroblastoma in 17 studies
Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deferoxamine previously has been shown to have potent activity in vitro against human neuroblastoma cells, activity that results from its ability to chelate iron." | 7.67 | Mechanism of antineuroblastoma activity of deferoxamine in vitro. ( Blatt, J; Stitely, S; Taylor, SR, 1988) |
| "Deferoxamine previously has been shown to have potent activity in vitro against human neuroblastoma cells, activity that results from its ability to chelate iron." | 3.67 | Mechanism of antineuroblastoma activity of deferoxamine in vitro. ( Blatt, J; Stitely, S; Taylor, SR, 1988) |
| "Animals with implanted experimental brain tumors were investigated for discrimination of pathological regions from normal brain structures based on relaxation time differences." | 1.29 | Quantitative magnetic resonance imaging of rat brain tumors: in vivo NMR relaxometry for the discrimination of normal and pathological tissues. ( Bockhorst, K; Hoehn-Berlage, M, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 10 (58.82) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Juweid, ME | 1 |
| Menda, Y | 2 |
| O'Dorisio, MS | 2 |
| Bushnell, D | 1 |
| Blake, M | 1 |
| Madsen, M | 1 |
| Johnson, J | 1 |
| Graham, MM | 1 |
| Mackenzie, GG | 1 |
| Keen, CL | 1 |
| Oteiza, PI | 1 |
| Michaelis, M | 1 |
| Langer, K | 1 |
| Arnold, S | 1 |
| Doerr, HW | 1 |
| Kreuter, J | 1 |
| Cinatl, J | 1 |
| Pashankar, FD | 1 |
| Lauriero, F | 1 |
| Rubini, G | 2 |
| D'Addabbo, F | 1 |
| Rubini, D | 1 |
| Schettini, F | 1 |
| D'Addabbo, A | 2 |
| Häfeli, UO | 1 |
| Sweeney, SM | 1 |
| Beresford, BA | 1 |
| Humm, JL | 1 |
| Macklis, RM | 1 |
| Hoehn-Berlage, M | 1 |
| Bockhorst, K | 1 |
| Dörr, U | 2 |
| Sautter-Bihl, ML | 2 |
| Schilling, FH | 1 |
| Koscielniak, E | 1 |
| Treuner, J | 2 |
| Bihl, H | 2 |
| Schilling, F | 1 |
| Hashimoto, M | 1 |
| Fujimoto, K | 1 |
| Shinoda, S | 1 |
| Masuzawa, T | 1 |
| Simeone, G | 1 |
| Nitti, L | 1 |
| Alonso Rodríguez, M | 1 |
| Castejón Sánchez, I | 1 |
| Mariño Pfeiffer, E | 1 |
| Ramos Sanz, J | 1 |
| Martínez García, G | 1 |
| Escribano Arias, M | 1 |
| Freile García, I | 1 |
| Peiró Valgañón, V | 1 |
| Ortiz Berrocal, J | 1 |
| Gulec, SA | 1 |
| Drouant, GJ | 1 |
| Fuselier, J | 1 |
| Anthony, CT | 1 |
| Heneghan, J | 1 |
| DelCarpio, JB | 1 |
| Coy, DH | 1 |
| Murphy, WA | 1 |
| Woltering, EA | 1 |
| Kornreich, L | 1 |
| Horev, G | 1 |
| Kaplinsky, C | 1 |
| Ziv, N | 1 |
| Grünebaum, M | 1 |
| Algra, PR | 1 |
| Scheltens, P | 1 |
| Barkhof, F | 1 |
| Valk, J | 1 |
| Blatt, J | 1 |
| Taylor, SR | 1 |
| Stitely, S | 1 |
| Felix, R | 1 |
| Schörner, W | 1 |
| Laniado, M | 1 |
| Semmler, W | 1 |
1 review available for pentetic acid and Neuroblastoma
| Article | Year |
|---|---|
MIBG and somatostatin receptor analogs in children: current concepts on diagnostic and therapeutic use.
Topics: 3-Iodobenzylguanidine; Animals; Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; I | 2005 |
16 other studies available for pentetic acid and Neuroblastoma
| Article | Year |
|---|---|
111In-pentetreotide versus bone scintigraphy in the detection of bony metastases of neuroblastoma.
Topics: 3-Iodobenzylguanidine; Bone and Bones; Bone Neoplasms; Brain Neoplasms; Child; Child, Preschool; Fem | 2002 |
Zinc status of human IMR-32 neuroblastoma cells influences their susceptibility to iron-induced oxidative stress.
Topics: Apoptosis; Chelating Agents; Humans; Iron; Neuroblastoma; Oxidative Stress; Pentetic Acid; Reactive | 2002 |
Pharmacological activity of DTPA linked to protein-based drug carrier systems.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Survival; Drug Carrie | 2004 |
I-131 MIBG scintigraphy of neuroectodermal tumors. Comparison between I-131 MIBG and In-111 DTPA-octreotide.
Topics: 3-Iodobenzylguanidine; Adolescent; Adrenal Gland Neoplasms; Child, Preschool; Humans; Indium Radiois | 1995 |
Effective targeting of magnetic radioactive 90Y-microspheres to tumor cells by an externally applied magnetic field. Preliminary in vitro and in vivo results.
Topics: Animals; Cell Line; Cell Survival; Culture Techniques; Dose-Response Relationship, Radiation; Female | 1995 |
Quantitative magnetic resonance imaging of rat brain tumors: in vivo NMR relaxometry for the discrimination of normal and pathological tissues.
Topics: Analysis of Variance; Animals; Brain Edema; Brain Neoplasms; Contrast Media; Diagnosis, Differential | 1994 |
Somatostatin receptor scintigraphy (SRS): a new diagnostic tool in neuroblastoma (NB)?
Topics: 3-Iodobenzylguanidine; Antineoplastic Agents; Child, Preschool; DNA, Neoplasm; Female; Humans; Indiu | 1994 |
Somatostatin receptor imaging: a new horizon in the diagnostic management of neuroblastoma.
Topics: 3-Iodobenzylguanidine; Chromosome Deletion; Chromosomes, Human, Pair 1; Female; Follow-Up Studies; H | 1994 |
Magnetic resonance imaging of ganglion cell tumours.
Topics: Adolescent; Adult; Brain Neoplasms; Cerebellar Neoplasms; Cerebral Ventricle Neoplasms; Contrast Med | 1993 |
Description of a multicompartmental model of the biodistribution of 111In-DTPA-D-Phe-1-octreotide in human.
Topics: Adenocarcinoma; Carcinoma, Small Cell; Computer Simulation; Female; Humans; Indium Radioisotopes; Ki | 1995 |
[Eight year history of neuroblastoma in an adult patient. Value of 123I-MIBG and 111In-DTPA-D-Phe-octreotide scintigraphy].
Topics: 3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Adult; Biomarkers, Tumor; Bone Marrow; Bone Neoplasm | 1999 |
Antitumor and antiangiogenic effects of somatostatin receptor-targeted in situ radiation with (111)In-DTPA-JIC 2DL.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Breast Neoplasms; Contrast Media; Female; Humans; In V | 2001 |
Neuroblastoma: evaluation with contrast enhanced MR imaging.
Topics: Child; Child, Preschool; Contrast Media; Female; Gadolinium DTPA; Head and Neck Neoplasms; Humans; I | 1991 |
Intracranial ganglioglioma: MR imaging.
Topics: Brain Neoplasms; Child; Gadolinium DTPA; Humans; Image Enhancement; Magnetic Resonance Imaging; Neur | 1990 |
Mechanism of antineuroblastoma activity of deferoxamine in vitro.
Topics: 2,2'-Dipyridyl; Cell Cycle; Cell Line; Cell Survival; Deferoxamine; DNA Replication; Humans; Neurobl | 1988 |
[Contrast media in magnetic resonance tomography. A review. 2. Biological basis, research technic and clinical application of gadolinium-DTPA in the diagnosis of intracranial tumors].
Topics: Adult; Brain Neoplasms; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurobla | 1985 |