Page last updated: 2024-10-30

kinetin and Neuroblastoma

kinetin has been researched along with Neuroblastoma in 6 studies

Kinetin: A furanyl adenine found in PLANTS and FUNGI. It has plant growth regulation effects.
cytokinin : A phytohormone that promote cell division, or cytokinesis, in plant roots and shoots.
kinetin : A member of the class of 6-aminopurines that is adenine carrying a (furan-2-ylmethyl) substituent at the exocyclic amino group.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" To better understand the role of cell cycle proteins in DNA-damage induced neuronal cell death, we examined various cell cycle proteins during camptothecin-induced death of human neuroblastoma cells."3.73DNA damage induces cdk2 protein levels and histone H2B phosphorylation in SH-SY5Y neuroblastoma cells. ( Bowser, R; Caltagarone, J; Smith, MA; Yu, X, 2005)
" In this study we investigated the relationship between these two phenomena during olomoucine- and roscovitin-induced apoptosis in human lung cancer and neuroblastoma cell lines."3.69Plasma membrane alterations and cytoskeletal changes in apoptosis. ( Kuijpers, HJ; Ramaekers, FC; Reutelingsperger, CP; Schutte, B; van Engeland, M, 1997)
" To this end, nonsmall cell lung cancer (NSCLC) cell line MR65 and neuroblastoma cell line CHP-212 were pulse labeled with bromodeoxyuridine (BrdUrd) and chased in culture medium, to which various concentrations of olomoucine or roscovitine were added."3.69The effect of the cyclin-dependent kinase inhibitor olomoucine on cell cycle kinetics. ( Henfling, ME; Meijer, L; Nieland, L; Ramaekers, FC; Schutte, B; van Engeland, M, 1997)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sevimli-Gur, C1
Cetin, B1
Akay, S1
Gulce-Iz, S1
Yesil-Celiktas, O1
Ribas, J2
Boix, J2
Yu, X1
Caltagarone, J1
Smith, MA1
Bowser, R1
Gomez-Arbones, X1
van Engeland, M2
Kuijpers, HJ1
Ramaekers, FC2
Reutelingsperger, CP1
Schutte, B2
Nieland, L1
Henfling, ME1
Meijer, L1

Other Studies

6 other studies available for kinetin and Neuroblastoma

ArticleYear
Extracts from black carrot tissue culture as potent anticancer agents.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2013, Volume: 68, Issue:3

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Anthocyanins; Antineoplastic Agents, Phytogenic; Breast Neo

2013
Cell differentiation, caspase inhibition, and macromolecular synthesis blockage, but not BCL-2 or BCL-XL proteins, protect SH-SY5Y cells from apoptosis triggered by two CDK inhibitory drugs.
    Experimental cell research, 2004, Apr-15, Volume: 295, Issue:1

    Topics: Apoptosis; bcl-X Protein; Caspase Inhibitors; Cell Differentiation; Cell Line, Tumor; Cell Survival;

2004
DNA damage induces cdk2 protein levels and histone H2B phosphorylation in SH-SY5Y neuroblastoma cells.
    Journal of Alzheimer's disease : JAD, 2005, Volume: 8, Issue:1

    Topics: Camptothecin; Caspase 3; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; Cy

2005
Caspase 8/10 are not mediating apoptosis in neuroblastoma cells treated with CDK inhibitory drugs.
    European journal of pharmacology, 2005, Nov-07, Volume: 524, Issue:1-3

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 10; Caspase 8; Caspase 9; Caspase Inhibitors; Ca

2005
Plasma membrane alterations and cytoskeletal changes in apoptosis.
    Experimental cell research, 1997, Sep-15, Volume: 235, Issue:2

    Topics: Actins; Annexin A5; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Membrane; Chromatin; Cytoskeleto

1997
The effect of the cyclin-dependent kinase inhibitor olomoucine on cell cycle kinetics.
    Experimental cell research, 1997, Oct-10, Volume: 236, Issue:1

    Topics: Antimetabolites; Apoptosis; Bromodeoxyuridine; Carcinoma, Non-Small-Cell Lung; CDC2 Protein Kinase;

1997