3,4-dihydroxyphenylacetic acid has been researched along with Neuroblastoma in 19 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report quantitative data on beta-glucuronidase- and sulfatase-hydrolyzable conjugates of homovanillic acid, 3,4-dihydroxyphenylacetic acid, p-hydroxyphenylacetic acid, and vanillic acid in the urine of 20 apparently normal and healthy control persons and of three patients with neuroblastoma." | 7.66 | Urinary excretion of conjugated homovanillic acid, 3,4-dihydroxyphenylacetic acid, p-hydroxyphenylacetic acid, and vanillic acid by persons on their usual diet and patients with neuroblastoma. ( Groen, A; Muskiet, FA, 1979) |
| " So, these results suggest that an early production of DOPAL could produce delayed toxic effects on SH-SY5Y cells." | 5.32 | Toxicity of a treatment associating dopamine and disulfiram for catecholaminergic neuroblastoma SH-SY5Y cells: relationships with 3,4-dihydroxyphenylacetaldehyde formation. ( Bonnet, JJ; Costentin, J; Dingeval, MG; Janin, F; Legros, H, 2004) |
| " N-Methyl(R)salsolinol induced DNA damage to human neuroblastoma SH-SY5Y cells, which could be prevented by anti-oxidants and cycloheximide." | 3.70 | Oxidation of N-methyl(R)salsolinol: involvement to neurotoxicity and neuroprotection by endogenous catechol isoquinolines. ( Dostert, P; Kasamatsu, T; Maruyama, W; Naoi, M, 1998) |
| "We report quantitative data on beta-glucuronidase- and sulfatase-hydrolyzable conjugates of homovanillic acid, 3,4-dihydroxyphenylacetic acid, p-hydroxyphenylacetic acid, and vanillic acid in the urine of 20 apparently normal and healthy control persons and of three patients with neuroblastoma." | 3.66 | Urinary excretion of conjugated homovanillic acid, 3,4-dihydroxyphenylacetic acid, p-hydroxyphenylacetic acid, and vanillic acid by persons on their usual diet and patients with neuroblastoma. ( Groen, A; Muskiet, FA, 1979) |
| " So, these results suggest that an early production of DOPAL could produce delayed toxic effects on SH-SY5Y cells." | 1.32 | Toxicity of a treatment associating dopamine and disulfiram for catecholaminergic neuroblastoma SH-SY5Y cells: relationships with 3,4-dihydroxyphenylacetaldehyde formation. ( Bonnet, JJ; Costentin, J; Dingeval, MG; Janin, F; Legros, H, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (36.84) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hellmann-Regen, J | 1 |
| Gertz, K | 1 |
| Uhlemann, R | 1 |
| Colla, M | 1 |
| Endres, M | 1 |
| Kronenberg, G | 1 |
| Laifenfeld, D | 1 |
| Klein, E | 1 |
| Ben-Shachar, D | 1 |
| PETRASEK, J | 1 |
| DUBOVSKY, J | 1 |
| VICH, Z | 1 |
| Legros, H | 1 |
| Dingeval, MG | 1 |
| Janin, F | 1 |
| Costentin, J | 1 |
| Bonnet, JJ | 1 |
| Sasaki, M | 1 |
| Sanada, H | 1 |
| Jiang, H | 1 |
| Jiang, Q | 1 |
| Liu, W | 1 |
| Feng, J | 1 |
| Mazzulli, JR | 1 |
| Mishizen, AJ | 1 |
| Giasson, BI | 1 |
| Lynch, DR | 1 |
| Thomas, SA | 1 |
| Nakashima, A | 1 |
| Nagatsu, T | 1 |
| Ota, A | 1 |
| Ischiropoulos, H | 1 |
| Adams, FS | 1 |
| La Rosa, FG | 1 |
| Kumar, S | 1 |
| Edwards-Prasad, J | 1 |
| Kentroti, S | 1 |
| Vernadakis, A | 1 |
| Freed, CR | 1 |
| Prasad, KN | 1 |
| Naoi, M | 1 |
| Maruyama, W | 1 |
| Kasamatsu, T | 1 |
| Dostert, P | 1 |
| Xie, T | 1 |
| McCann, UD | 1 |
| Kim, S | 1 |
| Yuan, J | 1 |
| Ricaurte, GA | 1 |
| Eldrup, E | 1 |
| Clausen, N | 1 |
| Scherling, B | 1 |
| Schmiegelow, K | 1 |
| Zuddas, A | 1 |
| Mancosu, C | 1 |
| Lilliu, V | 1 |
| Sorrentino, G | 1 |
| di Porzio, U | 1 |
| Cianchetti, C | 1 |
| Muskiet, FA | 2 |
| Fremouw-Ottevangers, DC | 1 |
| van der Meulen, J | 1 |
| Wolthers, BG | 1 |
| de Vries, JA | 1 |
| Groen, A | 1 |
| Peyrin, L | 1 |
| Cottet-Emard, JM | 1 |
| Claustre, B | 1 |
| Horellou, P | 1 |
| Marlier, L | 1 |
| Privat, A | 1 |
| Darchen, F | 1 |
| Scherman, D | 1 |
| Henry, JP | 1 |
| Mallet, J | 1 |
| Ghahary, A | 1 |
| Vriend, J | 1 |
| Cheng, KW | 1 |
| Tuchman, M | 1 |
| Stoeckeler, JS | 1 |
| Ito, S | 1 |
| Kato, T | 1 |
| Maruta, K | 1 |
| Jimbow, K | 1 |
| Fujita, K | 1 |
1 review available for 3,4-dihydroxyphenylacetic acid and Neuroblastoma
| Article | Year |
|---|---|
[3,4-Dihydroxyphenylacetic acid (DOPAC)].
Topics: 3,4-Dihydroxyphenylacetic Acid; Addison Disease; Adrenal Gland Neoplasms; Alzheimer Disease; Biomark | 2005 |
18 other studies available for 3,4-dihydroxyphenylacetic acid and Neuroblastoma
| Article | Year |
|---|---|
Retinoic acid as target for local pharmacokinetic interaction with modafinil in neural cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antineoplastic Agents; Benzhydryl Compounds; Cell Different | 2012 |
Norepinephrine alters the expression of genes involved in neuronal sprouting and differentiation: relevance for major depression and antidepressant mechanisms.
Topics: 3,4-Dihydroxyphenylacetic Acid; Antigens, Differentiation; Cell Differentiation; Cell Division; Cell | 2002 |
[EXCRETION OF 3,4-DIHYDROXYPHENYLACETIC ACID (DOPAC) IN PATIENTS WITH NEUROBLASTOMA AND PHEOCHROMOCYTOMA].
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Gland Neoplasms; Chromatography; Humans; Neuroblastoma; Phen | 1964 |
Toxicity of a treatment associating dopamine and disulfiram for catecholaminergic neuroblastoma SH-SY5Y cells: relationships with 3,4-dihydroxyphenylacetaldehyde formation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Catecholamines; Cell Line, Tumor; Cell Survival; Disulfiram; Dopamin | 2004 |
Parkin suppresses the expression of monoamine oxidases.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; B-Lymphocytes; Binding Sites; Cell Line, Transformed; Cell | 2006 |
Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Amino Acid Substitution; Animals; Catechols; Cell D | 2006 |
Characterization and transplantation of two neuronal cell lines with dopaminergic properties.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Bucladesine; Butyrates; Butyric Acid; Ca | 1996 |
Oxidation of N-methyl(R)salsolinol: involvement to neurotoxicity and neuroprotection by endogenous catechol isoquinolines.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Corpus Striatum; Cycloheximide; Disease Model | 1998 |
Effect of temperature on dopamine transporter function and intracellular accumulation of methamphetamine: implications for methamphetamine-induced dopaminergic neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Brain; Carri | 2000 |
Evaluation of plasma 3,4-dihydroxyphenylacetic acid (DOPAC) and plasma 3,4-dihydroxyphenylalanine (DOPA) as tumor markers in children with neuroblastoma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Biomarkers, Tumor; Case-Control Studies; Child; C | 2001 |
6R-Tetrahydrobiopterin induces dopamine synthesis in a human neuroblastoma cell line, LA-N-1. A cellular model of DOPA-responsive dystonia.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Biopterins; Dopamine; Dopamine Antagonists; Dys | 2002 |
Determination of some L-3,4-dihydroxyphenylalanine and dopamine metabolites in urine by means of mass fragmentography.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Adult; Aging; Child; Child, Presch | 1978 |
Urinary excretion of conjugated homovanillic acid, 3,4-dihydroxyphenylacetic acid, p-hydroxyphenylacetic acid, and vanillic acid by persons on their usual diet and patients with neuroblastoma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Animals; Child; Child, Preschool; Glucuronidase; Homovanillic | 1979 |
Studies on urinary DOPAC in man by means of a sensitive automated procedure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Addison Disease; Adrenal Gland Neoplasms; Adult; Aged; Autoanalysis; | 1978 |
Exogeneous expression of L-dopa and dopamine in various cell lines following transfer of rat and human tyrosine hydroxylase cDNA: grafting in an animal model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; DNA; Dopamine; Enz | 1990 |
Modification of the indolamine content in neuroblastoma x glioma hybrid NG108-15 cells upon induced differentiation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Biogenic Monoamines; Bucladesine; Cell Differentiation; Dopamine; Gl | 1989 |
Conjugated versus "free" acidic metabolites of catecholamines in random urine samples: significance for the diagnosis of neuroblastoma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Catecholamines; Child; Child, Preschool; Creatinine; Homovanillic Ac | 1988 |
"Total" acidic metabolites of catecholamines in urine as determined by hydrolysis with hydriodic acid and liquid chromatography: application to patients with neuroblastoma and melanoma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acids; Adult; Catecholamines; Child; Child, Preschool; Chromatograph | 1985 |