3-methoxytyramine has been researched along with Neuroblastoma in 9 studies
3-methoxytyramine: RN given refers to parent cpd
3-methoxytyramine : A monomethoxybenzene that is dopamine in which the hydroxy group at position 3 is replaced by a methoxy group. It is a metabolite of the neurotransmitter dopamine and considered a potential biomarker of pheochromocytomas and paragangliomas.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Elevated urinary 3-methoxytyramine (3MT) level at diagnosis was recently put forward as independent risk factor for poor prognosis in neuroblastoma." | 8.12 | Urinary 3-Methoxytyramine Is a Biomarker for MYC Activity in Patients With Neuroblastoma. ( Barco, S; Cangemi, G; Fiocco, M; Koster, J; Leen, R; Matser, YAH; Meinsma, R; Savci-Heijink, D; Tytgat, GAM; Valentijn, LJ; van Kuilenburg, ABP; Verly, IRN; Volckmann, R, 2022) |
| "Plasma concentrations of 3-methoxytyramine, normetanephrine, and metanephrine were measured in two pediatric cohorts: (i) 96 children with confirmed neuroblastoma and (ii) 41 children with signs and symptoms of a catecholamine-producing tumor or other neoplasms and in whom neuroblastoma was excluded." | 7.96 | Biochemical testing for neuroblastoma using plasma free 3-O-methyldopa, 3-methoxytyramine, and normetanephrine. ( Berthold, F; Butch, ER; Eisenhofer, G; Furman, WL; Hero, B; Huebner, A; Lovorn, E; Mangelis, A; Peitzsch, M; Santana, VM; Shulkin, BL, 2020) |
| "A substantial number of patients with neuroblastoma (NB) have increased excretion of catecholamines and metanephrines." | 7.91 | Plasma free metanephrines for diagnosis of neuroblastoma patients. ( Barco, S; Cangemi, G; Conte, M; Corrias, MV; de Sain-van der Velden, M; Garaventa, A; Sorrentino, S; Tripodi, G; Tytgat, G; van der Ham, M; van Kuilenburg, A; Verly, I, 2019) |
| "Plasma concentrations of 3-methoxytyramine, normetanephrine, and metanephrine were measured in two pediatric cohorts: (i) 96 children with confirmed neuroblastoma and (ii) 41 children with signs and symptoms of a catecholamine-producing tumor or other neoplasms and in whom neuroblastoma was excluded." | 3.96 | Biochemical testing for neuroblastoma using plasma free 3-O-methyldopa, 3-methoxytyramine, and normetanephrine. ( Berthold, F; Butch, ER; Eisenhofer, G; Furman, WL; Hero, B; Huebner, A; Lovorn, E; Mangelis, A; Peitzsch, M; Santana, VM; Shulkin, BL, 2020) |
| "A substantial number of patients with neuroblastoma (NB) have increased excretion of catecholamines and metanephrines." | 3.91 | Plasma free metanephrines for diagnosis of neuroblastoma patients. ( Barco, S; Cangemi, G; Conte, M; Corrias, MV; de Sain-van der Velden, M; Garaventa, A; Sorrentino, S; Tripodi, G; Tytgat, G; van der Ham, M; van Kuilenburg, A; Verly, I, 2019) |
| "Neuroblastomas are malignant tumors derived embryonically from the neural crest." | 1.29 | Urinary excretion of methylated catecholamine metabolites in a child with neuroblastoma maturing into ganglioneuroma. ( Bekri, S; Candito, M; Chambon, P; Deville, A; Soler, C; Thyss, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Verly, IRN | 2 |
| Matser, YAH | 1 |
| Leen, R | 1 |
| Meinsma, R | 1 |
| Fiocco, M | 2 |
| Koster, J | 1 |
| Volckmann, R | 1 |
| Savci-Heijink, D | 1 |
| Cangemi, G | 2 |
| Barco, S | 2 |
| Valentijn, LJ | 1 |
| Tytgat, GAM | 2 |
| van Kuilenburg, ABP | 2 |
| Peitzsch, M | 1 |
| Butch, ER | 1 |
| Lovorn, E | 1 |
| Mangelis, A | 1 |
| Furman, WL | 1 |
| Santana, VM | 1 |
| Hero, B | 1 |
| Berthold, F | 1 |
| Shulkin, BL | 1 |
| Huebner, A | 1 |
| Eisenhofer, G | 1 |
| Abeling, NGGM | 1 |
| Goorden, SMI | 1 |
| Vaz, FM | 1 |
| van Noesel, MM | 1 |
| Zwaan, CM | 1 |
| Kaspers, GJL | 1 |
| Merks, JHM | 1 |
| Caron, HN | 1 |
| Verly, I | 1 |
| Corrias, MV | 1 |
| Sorrentino, S | 1 |
| Conte, M | 1 |
| Tripodi, G | 1 |
| Tytgat, G | 1 |
| van Kuilenburg, A | 1 |
| van der Ham, M | 1 |
| de Sain-van der Velden, M | 1 |
| Garaventa, A | 1 |
| Lam, L | 1 |
| Woollard, GA | 1 |
| Teague, L | 1 |
| Davidson, JS | 1 |
| Jiang, H | 1 |
| Jiang, Q | 1 |
| Liu, W | 1 |
| Feng, J | 1 |
| Candito, M | 2 |
| Soler, C | 1 |
| Deville, A | 2 |
| Bekri, S | 1 |
| Chambon, P | 2 |
| Thyss, A | 2 |
| Faraj, BA | 1 |
| Camp, VM | 1 |
| Pruitt, AW | 1 |
| Isaacs, JW | 1 |
| Ali, FM | 1 |
| Albertini, M | 1 |
| Politano, S | 1 |
| Mariani, R | 1 |
9 other studies available for 3-methoxytyramine and Neuroblastoma
| Article | Year |
|---|---|
Urinary 3-Methoxytyramine Is a Biomarker for MYC Activity in Patients With Neuroblastoma.
Topics: Biomarkers, Tumor; Dopamine; Humans; N-Myc Proto-Oncogene Protein; Neuroblastoma; Prospective Studie | 2022 |
Biochemical testing for neuroblastoma using plasma free 3-O-methyldopa, 3-methoxytyramine, and normetanephrine.
Topics: Adolescent; Biomarkers, Tumor; Case-Control Studies; Child; Child, Preschool; Dopamine; Female; Foll | 2020 |
3-Methoxytyramine: An independent prognostic biomarker that associates with high-risk disease and poor clinical outcome in neuroblastoma patients.
Topics: Adolescent; Biomarkers, Tumor; Child; Child, Preschool; Cohort Studies; Disease-Free Survival; Dopam | 2018 |
Plasma free metanephrines for diagnosis of neuroblastoma patients.
Topics: Child; Child, Preschool; Chromatography; Cohort Studies; Dopamine; Female; Humans; Infant; Infant, N | 2019 |
Clinical validation of urine 3-methoxytyramine as a biomarker of neuroblastoma and comparison with other catecholamine-related biomarkers.
Topics: Biomarkers, Tumor; Case-Control Studies; Child; Child, Preschool; Chromatography, High Pressure Liqu | 2017 |
Parkin suppresses the expression of monoamine oxidases.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; B-Lymphocytes; Binding Sites; Cell Line, Transformed; Cell | 2006 |
Urinary excretion of methylated catecholamine metabolites in a child with neuroblastoma maturing into ganglioneuroma.
Topics: Adrenal Gland Neoplasms; Catecholamines; Dopamine; Ganglioneuroma; Homovanillic Acid; Humans; Infant | 1996 |
The measurement of 3-o-methyldopamine in urine and plasma by a rapid and specific radioimmunoassay.
Topics: Adolescent; Adult; Animals; Binding Sites, Antibody; Child; Child, Preschool; Dopamine; Haptens; Hem | 1977 |
Methylated catecholamine metabolites for diagnosis of neuroblastoma.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Dopamine; Epinephrine; Female; Homovanill | 1992 |