idebenone has been researched along with Neuroblastoma in 2 studies
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we found that exposure of the dopaminergic neuroblastoma SHSY-5Y cells to 1-10 μM idebenone for 72 h had no effect on the cell viability revealed by trypan blue exclusion assay and MTT assay." | 7.77 | Idebenone induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. ( Pham, L; Tai, KK; Truong, DD, 2011) |
| " In this study, we found that exposure of the dopaminergic neuroblastoma SHSY-5Y cells to 1-10 μM idebenone for 72 h had no effect on the cell viability revealed by trypan blue exclusion assay and MTT assay." | 3.77 | Idebenone induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. ( Pham, L; Tai, KK; Truong, DD, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Gaetano, F | 1 |
| Scala, A | 1 |
| Celesti, C | 1 |
| Lambertsen Larsen, K | 1 |
| Genovese, F | 1 |
| Bongiorno, C | 1 |
| Leggio, L | 1 |
| Iraci, N | 2 |
| Mazzaglia, A | 1 |
| Ventura, CA | 1 |
| Tai, KK | 1 |
| Pham, L | 1 |
| Truong, DD | 1 |
2 other studies available for idebenone and Neuroblastoma
| Article | Year |
|---|---|
Amphiphilic Cyclodextrin Nanoparticles as Delivery System for Idebenone: A Preformulation Study.
Topics: Antioxidants; Cyclodextrins; Drug Carriers; Humans; Hydrogen Peroxide; Nanoparticles; Neuroblastoma; | 2023 |
Idebenone induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells.
Topics: Antioxidants; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Cytochromes c; DNA Fragmentatio | 2011 |