1-methyl-3-isobutylxanthine has been researched along with Neuroblastoma in 43 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Excerpt | Relevance | Reference |
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"To clarify the functional significance of type IV phosphodiesterase (PDEIV) in neurons and glia cells [3H]rolipram binding and phosphodiesterase (PDE) activity were examined in cytosol and membrane fractions of neuroblastoma N18TG-2 and glioma C6Bu-1 cells." | 7.69 | [3H]Rolipram binding and phosphodiesterase activity in neuroblastoma N18TG-2 and glioma C6Bu-1. ( Hasegawa, H; Murayama, T; Nogiri, S; Nomura, Y; Tohda, M, 1994) |
"Cell hybrids (BIM) were produced between human neuroblastoma cells (IMR-32) and thymidine auxotrophs (B3T) of rat nerve-like cells (B103) in order to obtain cell lines undergoing stable neuronal differentiation." | 7.68 | Spontaneous and cAMP-dependent induction of a resting phase and neurite formation in cell hybrids between human neuroblastoma cells and thymidine auxotrophs of rat nerve-like cells. ( Adachi, Y; Furuyama, J; Hatanaka, M; Ishii, K; Sakamoto, H, 1990) |
"Regulation of cholecystokinin (CCK) and the proto-oncogene c-fos mRNA expression was studied in the human neuroblastoma cell line SK-N-MC." | 7.68 | Phorbol 12-myristate-13-acetate (PMA) stimulates a differential expression of cholecystokinin (CCK) and c-fos mRNA in a human neuroblastoma cell line. ( Folkesson, R; Monstein, HJ, 1991) |
"Treatment with reserpine, which increases conversion of peptide B to the heptapeptide in bovine chromaffin cells in culture does not stimulate the accumulation of Met-enkephalyl-Arg6-Phe7 in the human neuroblastoma cells." | 5.27 | Met-enkephalyl-Arg6-Phe7 immunoreactivity in a human neuroblastoma cell line: effect of dibutyryl 3':5'-cyclic AMP and reserpine. ( Adams, M; Boarder, MR; Marriott, D, 1986) |
"The prostacyclin mimetic cicaprost increased phosphorylation of extracellular signal-regulated kinases 1 and 2 (ERK1/2) in Chinese hamster ovary cells transiently expressing human (hIP-CHO) or mouse prostacyclin (mIP-CHO) receptors, but not in human neuroblastoma SK-N-SH cells or rat/mouse neuroblastoma-glioma NG108-15 cells which endogenously express IP receptors." | 3.72 | Prostacyclin receptor-mediated activation of extracellular signal-regulated kinases 1 and 2. ( Chow, KB; Chu, KM; Wise, H; Wong, YH, 2004) |
"Acute incubation of NMDA with neuroblastoma x glioma hybrid (NG108-15) cells or neuroblastoma SK-N-SH cells produced significant attenuation of nociceptin/orphanin FQ (N/OFQ)-induced activation of G protein and inhibition of adenylyl cyclase." | 3.70 | Attenuation of nociceptin/orphanin FQ-induced signaling by N-methyl-D-aspartate in neuronal cells. ( Ma, L; Pei, G; Xin, SM; Zhang, Y; Zhao, J, 1998) |
" We provide evidence in support of the existence of mu* in human neuroblastoma cells, SH-SY5Y, and mu* upregulation during morphine treatment." | 3.69 | Constitutive mu opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence. ( Bilsky, EJ; Porreca, F; Sadée, W; Wang, Z, 1994) |
"To clarify the functional significance of type IV phosphodiesterase (PDEIV) in neurons and glia cells [3H]rolipram binding and phosphodiesterase (PDE) activity were examined in cytosol and membrane fractions of neuroblastoma N18TG-2 and glioma C6Bu-1 cells." | 3.69 | [3H]Rolipram binding and phosphodiesterase activity in neuroblastoma N18TG-2 and glioma C6Bu-1. ( Hasegawa, H; Murayama, T; Nogiri, S; Nomura, Y; Tohda, M, 1994) |
"Pharmacological characteristics of native neuronal nicotinic acetylcholine receptor-mediated ion currents in mouse N1E-115 neuroblastoma cells have been investigated by superfusion of voltage clamped cells with known concentrations of the agonists acetylcholine, nicotine and cytisine, and the antagonists alpha-bungarotoxin and neuronal bungarotoxin." | 3.69 | alpha 4 beta 2 subunit combination specific pharmacology of neuronal nicotinic acetylcholine receptors in N1E-115 neuroblastoma cells. ( Abraham, D; Oortgiesen, M; Vijverberg, HP; Zwart, R, 1994) |
"Cell hybrids (BIM) were produced between human neuroblastoma cells (IMR-32) and thymidine auxotrophs (B3T) of rat nerve-like cells (B103) in order to obtain cell lines undergoing stable neuronal differentiation." | 3.68 | Spontaneous and cAMP-dependent induction of a resting phase and neurite formation in cell hybrids between human neuroblastoma cells and thymidine auxotrophs of rat nerve-like cells. ( Adachi, Y; Furuyama, J; Hatanaka, M; Ishii, K; Sakamoto, H, 1990) |
"Regulation of cholecystokinin (CCK) and the proto-oncogene c-fos mRNA expression was studied in the human neuroblastoma cell line SK-N-MC." | 3.68 | Phorbol 12-myristate-13-acetate (PMA) stimulates a differential expression of cholecystokinin (CCK) and c-fos mRNA in a human neuroblastoma cell line. ( Folkesson, R; Monstein, HJ, 1991) |
"Chronic pertussis toxin treatment (5 days) of NG108-15 neuroblastoma X glioma hybrid cells had no significant effect on basal cyclic AMP levels whereas it effectively blocked the inhibitory action of acute (10 min) exposure of carbachol (10(-4)M) on intracellular cyclic AMP accumulation, stimulated by prostaglandin E1." | 3.67 | Chronic exposure to pertussis toxin alters muscarinic receptor-mediated regulation of cyclic AMP metabolism in neuroblastoma x glioma NG108-15 hybrid cells. ( Askelöf, P; Bartfai, T; Gillenius, P; Westlind-Danielsson, A, 1988) |
" Upon pretreatment with morphine over greater than or equal to 12 h, a fourfold shift of the PGE1-morphine dose-response curve was observed, whether or not IBMX was added." | 1.28 | Regulation of cyclic AMP by the mu-opioid receptor in human neuroblastoma SH-SY5Y cells. ( Duan, DS; Eiger, S; Lameh, J; Sadée, W; Yu, VC, 1990) |
" The VIP/PHM-27 gene dosage was unchanged by Bt2cAMP and phorbol esters." | 1.27 | Synergistic stimulation of VIP/PHM-27 gene expression by cyclic AMP and phorbol esters in human neuroblastoma cells. ( Hayakawa, Y; Nishizawa, M; Ohsawa, K; Okamoto, H; Yamagami, T; Yamamoto, H; Yanaihara, N, 1985) |
" At peptide concentrations of 1 microM clear-cut plateaus of the dose-response curves are not yet reached." | 1.27 | Atrial natriuretic hormones raise the level of cyclic GMP in neural cell lines. ( Friedl, A; Hamprecht, B; Harmening, C, 1986) |
"Carbachol treatment of cells resulted in down-regulation of muscarinic cholinergic receptors to 45." | 1.27 | Agonist-induced down-regulation of muscarinic cholinergic and alpha 2-adrenergic receptors after inactivation of Ni by pertussis toxin. ( Hoffman, BB; Thomas, JM, 1986) |
"Treatment with reserpine, which increases conversion of peptide B to the heptapeptide in bovine chromaffin cells in culture does not stimulate the accumulation of Met-enkephalyl-Arg6-Phe7 in the human neuroblastoma cells." | 1.27 | Met-enkephalyl-Arg6-Phe7 immunoreactivity in a human neuroblastoma cell line: effect of dibutyryl 3':5'-cyclic AMP and reserpine. ( Adams, M; Boarder, MR; Marriott, D, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 16 (37.21) | 18.7374 |
1990's | 23 (53.49) | 18.2507 |
2000's | 3 (6.98) | 29.6817 |
2010's | 1 (2.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Leung, YM | 1 |
Huang, CF | 1 |
Chao, CC | 1 |
Lu, DY | 1 |
Kuo, CS | 1 |
Cheng, TH | 1 |
Chang, LY | 1 |
Chou, CH | 1 |
Chu, KM | 1 |
Chow, KB | 1 |
Wong, YH | 1 |
Wise, H | 1 |
Billups, D | 1 |
Billups, B | 1 |
Challiss, RA | 2 |
Nahorski, SR | 1 |
Hall, JM | 1 |
Strange, PG | 2 |
Freedman, SB | 1 |
Dawson, G | 5 |
Villereal, ML | 1 |
Miller, RJ | 1 |
Wang, Z | 1 |
Bilsky, EJ | 1 |
Porreca, F | 1 |
Sadée, W | 2 |
Tohda, M | 1 |
Murayama, T | 1 |
Hasegawa, H | 1 |
Nogiri, S | 1 |
Nomura, Y | 1 |
Zwart, R | 1 |
Abraham, D | 1 |
Oortgiesen, M | 1 |
Vijverberg, HP | 1 |
Inukai, T | 1 |
Chik, CL | 1 |
Ho, AK | 1 |
Bergsbaken, CL | 1 |
Sommers, SL | 1 |
Law, PY | 1 |
Morgan, AJ | 1 |
Murray, KJ | 1 |
Adler, EM | 1 |
Fink, JS | 1 |
Cai, Y | 1 |
Zhang, Y | 2 |
Wu, Y | 1 |
Pei, G | 2 |
Cibelli, G | 1 |
Jüngling, S | 1 |
Schoch, S | 1 |
Gerdes, HH | 1 |
Thiel, G | 1 |
Boddeke, HW | 1 |
Meigel, I | 1 |
Boeijinga, P | 1 |
Arbuckle, J | 1 |
Docherty, RJ | 1 |
Gylys, KH | 1 |
Tran, N | 1 |
Magendzo, K | 1 |
Zaki, P | 1 |
Evans, CJ | 1 |
Wojcikiewicz, RJ | 1 |
Luo, SG | 1 |
Zhao, J | 1 |
Xin, SM | 1 |
Ma, L | 1 |
Drake, WM | 1 |
Ajayi, A | 1 |
Lowe, SR | 1 |
Mirtella, A | 1 |
Bartlett, TJ | 1 |
Clark, AJ | 1 |
Sidhu, A | 1 |
Olde, B | 1 |
Humblot, N | 1 |
Kimura, K | 1 |
Gardner, N | 1 |
Roseboom, PH | 1 |
Urben, CM | 1 |
Kalin, NH | 1 |
Bennett, T | 1 |
Propst, F | 1 |
Moroder, L | 1 |
Wünsch, E | 1 |
Hamprecht, B | 2 |
Hall, AK | 1 |
Thomas, JM | 2 |
Vagelos, R | 1 |
Hoffman, BB | 2 |
Ajiro, K | 1 |
Shibata, K | 1 |
Nishikawa, Y | 1 |
McAtee, P | 2 |
Ishii, K | 1 |
Adachi, Y | 1 |
Hatanaka, M | 1 |
Sakamoto, H | 1 |
Furuyama, J | 1 |
Yu, VC | 1 |
Eiger, S | 1 |
Duan, DS | 1 |
Lameh, J | 1 |
Klann, E | 1 |
Shelton, KR | 1 |
Monstein, HJ | 1 |
Folkesson, R | 1 |
Ohsawa, K | 1 |
Hayakawa, Y | 1 |
Nishizawa, M | 1 |
Yamagami, T | 1 |
Yamamoto, H | 1 |
Yanaihara, N | 1 |
Okamoto, H | 1 |
Friedl, A | 1 |
Harmening, C | 1 |
Scheideler, MA | 1 |
Boarder, MR | 1 |
Marriott, D | 1 |
Adams, M | 1 |
Graeff, RM | 1 |
Walseth, TF | 1 |
Goldberg, ND | 1 |
Berry-Kravis, E | 1 |
Kazmierczak, BI | 1 |
Derechin, V | 1 |
Westlind-Danielsson, A | 1 |
Gillenius, P | 1 |
Askelöf, P | 1 |
Bartfai, T | 1 |
Baumgold, J | 1 |
Fishman, PH | 1 |
Akil, M | 1 |
Fisher, SK | 1 |
Ruusala, AI | 1 |
Mattsson, M | 1 |
Esscher, T | 1 |
Abrahamsson, L | 1 |
Jergil, B | 1 |
Påhlman, S | 1 |
43 other studies available for 1-methyl-3-isobutylxanthine and Neuroblastoma
Article | Year |
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Voltage-gated K+ channels play a role in cAMP-stimulated neuritogenesis in mouse neuroblastoma N2A cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Channels; Cell Differentiation; Cell Line, Tumor; Colf | 2011 |
Prostacyclin receptor-mediated activation of extracellular signal-regulated kinases 1 and 2.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain Neoplasms; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP | 2004 |
Modulation of Gq-protein-coupled inositol trisphosphate and Ca2+ signaling by the membrane potential.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium Signaling; Cell Line; Cell Line, Tumor; Cells, Culture | 2006 |
The use of a prostacyclin analogue, [3H]iloprost, for studying prostacyclin-binding sites on human platelets and neuronal hybrid cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding, Competitive; Blood Platelets; Brain; Cell Line; Cell | 1984 |
Identification and characterization of voltage-sensitive calcium channels in neuronal clonal cell lines.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain Neoplasms; Calcium Channel Blockers; Cell Transformation | 1984 |
Constitutive mu opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cerebral Ventricles; Cyclic AMP; Drug Tolerance; Ho | 1994 |
[3H]Rolipram binding and phosphodiesterase activity in neuroblastoma N18TG-2 and glioma C6Bu-1.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imi | 1994 |
alpha 4 beta 2 subunit combination specific pharmacology of neuronal nicotinic acetylcholine receptors in N1E-115 neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Alkaloids; Animals; Azocines; Bucladesine; Bungarotoxins | 1994 |
Vasoactive intestinal polypeptide stimulates cyclic AMP production in mouse N1E-115 neuroblastoma cells: modulation by a protein kinase C activator and ionomycin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carcin | 1994 |
Effect of forskolin and isobutylmethylxanthine on delta-opioid receptor activity in neuroblastoma x glioma NG108-15 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Differentiation; Colforsin; Cyclic AMP; Enkephalin, Leuci | 1993 |
Comparison of the effect of isobutylmethylxanthine and phosphodiesterase-selective inhibitors on cAMP levels in SH-SY5Y neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenylyl Cyclase Inhibitors; Cell Line; C | 1993 |
Calcium regulation of vasoactive intestinal polypeptide mRNA abundance in SH-SY5Y human neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Calcimycin; Calcium; Colforsin; Cyclic AMP; Gene Expression Regulation, | 1993 |
delta Opioid receptor in neuronal cells undergoes acute and homologous desensitization.
Topics: 1-Methyl-3-isobutylxanthine; Analgesics; Animals; Cerebral Cortex; Cyclic AMP; Dose-Response Relatio | 1996 |
Identification of a functional cAMP response element in the secretogranin II gene.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Bucladesine; Cell Differentiation; Chromogranin | 1996 |
Modulation by calcineurin of 5-HT3 receptor function in NG108-15 neuroblastoma x glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Brain Neoplasms; Calcineurin; Calmodulin- | 1996 |
cAMP decreases steady-state levels of delta-opioid receptor mRNA in NG108-15 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Dinoprostone; Neuroblastoma; Phosphodie | 1997 |
Phosphorylation of inositol 1,4,5-trisphosphate receptors by cAMP-dependent protein kinase. Type I, II, and III receptors are differentially susceptible to phosphorylation and are phosphorylated in intact cells.
Topics: 1-Methyl-3-isobutylxanthine; Calcium; Calcium Channels; Carbachol; Colforsin; Cyclic AMP; Cyclic AMP | 1998 |
Attenuation of nociceptin/orphanin FQ-induced signaling by N-methyl-D-aspartate in neuronal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Gliom | 1998 |
Desensitization of CGRP and adrenomedullin receptors in SK-N-MC cells: implications for the RAMP hypothesis.
Topics: 1-Methyl-3-isobutylxanthine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Intracellular | 1999 |
Regulation of human D1 dopamine receptor function and gene expression in SK-N-MC neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Benzazepine | 1999 |
Persistent corticotropin-releasing factor(1) receptor desensitization and downregulation in the human neuroblastoma cell line IMR-32.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Amphibian Proteins; Bromodeoxyuridine; Carrier Prote | 2001 |
Effect of a phosphodiesterase inhibitor on cyclic GMP changes induced by muscarinic agonists in mouse neuroblastoma cells [proceedings].
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cyclic GMP; Mice; Neuroblastoma; Parasympatho | 1978 |
The influence of secretin, glucagon and other peptides, of amino acids, prostaglandin endoperoxide analogues and diazepam on the level of adenosine 3',5'-cyclic monophosphate in neuroblastoma x glioma hybrid cells.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amino Acids; Cyclic AMP | 1979 |
Influence of cyclic AMP and serum factors upon expression of a retinoid-responsive gene in neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Amino Acid Sequence; Animals; Blood Physiological Phenomena; | 1992 |
Decreased cyclic AMP degradation in NG 108-15 neuroblastoma X glioma hybrid cells and S49 lymphoma cells chronically treated with drugs that inhibit adenylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Cyclic AMP; Glioma; | 1990 |
Subtype-specific cyclic AMP-dependent histone H1 phosphorylation at the differentiation of mouse neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Caffeine; Cell Differentiation; Cell Line; Colfor | 1990 |
Phospholipase C activity in NCB-20 cells is inhibited by protein kinase A-mediated phosphorylation of low molecular mass GTP-binding proteins.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Brain; Cell L | 1990 |
Spontaneous and cAMP-dependent induction of a resting phase and neurite formation in cell hybrids between human neuroblastoma cells and thymidine auxotrophs of rat nerve-like cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Axons; Bucladesine; Calcimycin; Cell Cycle; Cell Transformatio | 1990 |
Regulation of cyclic AMP by the mu-opioid receptor in human neuroblastoma SH-SY5Y cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Cell Line; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe | 1990 |
A lead-associated nuclear protein which increases in maturing brain and in differentiating neuroblastoma 2A cells exposed to cyclic AMP-elevating agents.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Western; Bra | 1990 |
Phorbol 12-myristate-13-acetate (PMA) stimulates a differential expression of cholecystokinin (CCK) and c-fos mRNA in a human neuroblastoma cell line.
Topics: 1-Methyl-3-isobutylxanthine; Base Sequence; Cell Line; Cholecystokinin; Gene Expression Regulation, | 1991 |
Synergistic stimulation of VIP/PHM-27 gene expression by cyclic AMP and phorbol esters in human neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cells, Cultured; Cyclic AMP; Drug Synergism; Gene Expressi | 1985 |
Atrial natriuretic hormones raise the level of cyclic GMP in neural cell lines.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Calcimycin; Calcium; Cell Line; Cyc | 1986 |
Direct demonstration of the activation of UDP-N-acetylgalactosamine: [GM3]N-acetylgalactosaminyltransferase by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Line; Cyclic AMP; Enkephalin, Leucine; Enkephalin, | 1986 |
Agonist-induced down-regulation of muscarinic cholinergic and alpha 2-adrenergic receptors after inactivation of Ni by pertussis toxin.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase | 1986 |
Met-enkephalyl-Arg6-Phe7 immunoreactivity in a human neuroblastoma cell line: effect of dibutyryl 3':5'-cyclic AMP and reserpine.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Bucladesine; Cell Line; Cyclic AMP; Enkephalin, Methionine | 1986 |
The dynamics of cGMP metabolism in neuroblastoma N1E-115 cells determined by 18O labeling of guanine nucleotide alpha-phosphoryls.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterase | 1987 |
Neuromodulator-mediated phosphorylation of specific proteins in a neurotumor hybrid cell line (NCB-20).
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Alprostadil; Animals; Brain; Calcimycin; | 1988 |
Chronic exposure to pertussis toxin alters muscarinic receptor-mediated regulation of cyclic AMP metabolism in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Atropine; Carbachol; Cyclic AMP; Glioma; Hybrid Cells; Neu | 1988 |
Muscarinic receptor-mediated increase in cAMP levels in SK-N-SH human neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Carbachol; Cell Line; Colforsin; Cyclic AMP; H | 1988 |
Rapid dephosphorylation of protein kinase C substrates by protein kinase A activators results from inhibition of diacylglycerol release.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Biological T | 1989 |
Muscarinic receptor-stimulated phosphoinositide turnover in human SK-N-SH neuroblastoma cells: differential inhibition by agents that elevate cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alprostadil; Bucladesine; Carbacho | 1989 |
12-O-tetradecanoyl-phorbol-13-acetate-induced differentiation of human neuroblastoma cells is not accompanied by an increase in the intracellular concentration of cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Clone Cells; Colchicine; Cyclic AMP; Mice; N | 1985 |