| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Astrocytoma, Grade IV
[description not available] | 0 | 4.86 | 4 | 2 |
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 1 | 6.86 | 4 | 2 |
Angiogenesis, Pathologic
[description not available] | 0 | 2.15 | 1 | 0 |
Invasiveness, Neoplasm
[description not available] | 0 | 2.15 | 1 | 0 |
Carcinoma, Non-Small Cell Lung
[description not available] | 0 | 2.17 | 1 | 0 |
Cancer of Lung
[description not available] | 0 | 6.8 | 9 | 3 |
Carcinoma, Non-Small-Cell Lung
A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy. | 0 | 2.17 | 1 | 0 |
Lung Neoplasms
Tumors or cancer of the LUNG. | 0 | 6.8 | 9 | 3 |
Hepatocellular Carcinoma
[description not available] | 0 | 2.44 | 2 | 0 |
Cancer of Liver
[description not available] | 0 | 2.44 | 2 | 0 |
Experimental Hepatoma
[description not available] | 0 | 2.05 | 1 | 0 |
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 2.44 | 2 | 0 |
Liver Neoplasms
Tumors or cancer of the LIVER. | 0 | 2.44 | 2 | 0 |
Carcinoma, Epidermoid
[description not available] | 0 | 6.43 | 9 | 2 |
Carcinoma, Squamous Cell
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 6.43 | 9 | 2 |
Adenocarcinoma, Basal Cell
[description not available] | 0 | 6.32 | 8 | 2 |
Carcinoma, Ehrlich Tumor
A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms. | 0 | 1.96 | 1 | 0 |
Adenocarcinoma
A malignant epithelial tumor with a glandular organization. | 0 | 6.32 | 8 | 2 |
Leucocythaemia
[description not available] | 0 | 2.67 | 3 | 0 |
Leukemia, Lymphocytic
[description not available] | 0 | 1.96 | 1 | 0 |
Granulocytic Leukemia
[description not available] | 0 | 2.36 | 2 | 0 |
Acute Myelogenous Leukemia
[description not available] | 0 | 1.96 | 1 | 0 |
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 2.67 | 3 | 0 |
Leukemia, Lymphoid
Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts. | 0 | 1.96 | 1 | 0 |
Leukemia, Myeloid
Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites. | 0 | 2.36 | 2 | 0 |
Leukemia, Myeloid, Acute
Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES. | 0 | 1.96 | 1 | 0 |
Lymphocytosis
Excess of normal lymphocytes in the blood or in any effusion. | 0 | 1.96 | 1 | 0 |
Atrophy
Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes. | 0 | 1.96 | 1 | 0 |
Hypertrophy
General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA). | 0 | 1.96 | 1 | 0 |
Cancer of Ovary
[description not available] | 0 | 2.37 | 2 | 0 |
Cystadenocarcinoma
A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed) | 0 | 1.96 | 1 | 0 |
Ovarian Neoplasms
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. | 1 | 4.37 | 2 | 0 |
Carcinoma, Oat Cell
[description not available] | 0 | 4.26 | 1 | 1 |
Carcinoma, Small Cell
An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7) | 0 | 4.26 | 1 | 1 |
Malignant Melanoma
[description not available] | 0 | 8.21 | 6 | 0 |
Melanoma
A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) | 0 | 3.21 | 6 | 0 |
Benign Neoplasms, Brain
[description not available] | 0 | 4.95 | 9 | 1 |
Glial Cell Tumors
[description not available] | 0 | 3.06 | 5 | 0 |
Arachnoidal Cerebellar Sarcoma, Circumscribed
[description not available] | 0 | 1.96 | 1 | 0 |
Anaplastic Ependymoma
[description not available] | 0 | 2.37 | 2 | 0 |
Local Neoplasm Recurrence
[description not available] | 0 | 3.06 | 5 | 0 |
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 1 | 6.95 | 9 | 1 |
Ependymoma
Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9) | 0 | 2.37 | 2 | 0 |
Glioma
Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21) | 0 | 3.06 | 5 | 0 |
Medulloblastoma
A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1) | 0 | 1.96 | 1 | 0 |
Cancer of Cervix
[description not available] | 0 | 2.88 | 4 | 0 |
Uterine Cervical Neoplasms
Tumors or cancer of the UTERINE CERVIX. | 0 | 2.88 | 4 | 0 |
Benign Neoplasms
[description not available] | 0 | 6.52 | 10 | 2 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 6.52 | 10 | 2 |
Experimental Neoplasms
[description not available] | 0 | 3.46 | 8 | 0 |
Anaplastic Astrocytoma
[description not available] | 0 | 2.65 | 3 | 0 |
Astrocytoma
Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082) | 0 | 7.65 | 3 | 0 |
Carcinoma 256, Walker
A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed) | 0 | 1.96 | 1 | 0 |
Leukocytopenia
[description not available] | 0 | 5 | 5 | 2 |
Leukopenia
A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000). | 0 | 5 | 5 | 2 |
Peripheral Nerve Neoplasms
[description not available] | 0 | 1.96 | 1 | 0 |
Peripheral Nervous System Neoplasms
Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1) | 0 | 1.96 | 1 | 0 |
Germinoblastoma
[description not available] | 0 | 2.88 | 4 | 0 |
Lymphoma
A general term for various neoplastic diseases of the lymphoid tissue. | 0 | 7.88 | 4 | 0 |
Cancer of Head
[description not available] | 0 | 1.96 | 1 | 0 |
Head and Neck Neoplasms
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651) | 0 | 1.96 | 1 | 0 |
Cancer of Pelvis
[description not available] | 0 | 1.96 | 1 | 0 |
Emesis
[description not available] | 0 | 3.75 | 2 | 1 |
Nausea
An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses. | 0 | 3.34 | 1 | 1 |
Vomiting
The forcible expulsion of the contents of the STOMACH through the MOUTH. | 0 | 3.75 | 2 | 1 |
Cancer of Kidney
[description not available] | 0 | 3.75 | 2 | 1 |
Kidney Neoplasms
Tumors or cancers of the KIDNEY. | 0 | 3.75 | 2 | 1 |
Anaplastic Oligodendroglioma
[description not available] | 0 | 1.96 | 1 | 0 |
Oligodendroglioma
A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655) | 0 | 1.96 | 1 | 0 |
Reticulum Cell-Like Sarcoma, Yoshida
[description not available] | 0 | 2.36 | 2 | 0 |
Neuroblastoma
A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 7.88 | 4 | 0 |
Armstrong Syndrome
[description not available] | 0 | 2.66 | 3 | 0 |
Breast Cancer
[description not available] | 0 | 2.36 | 2 | 0 |
Cancer of Colon
[description not available] | 0 | 1.95 | 1 | 0 |
Cancer of Rectum
[description not available] | 0 | 1.95 | 1 | 0 |
Osteogenic Sarcoma
[description not available] | 0 | 1.95 | 1 | 0 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 2.36 | 2 | 0 |
Colonic Neoplasms
Tumors or cancer of the COLON. | 0 | 1.95 | 1 | 0 |
Rectal Neoplasms
Tumors or cancer of the RECTUM. | 0 | 1.95 | 1 | 0 |
Osteosarcoma
A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed) | 0 | 1.95 | 1 | 0 |
Metastase
[description not available] | 0 | 4.04 | 3 | 1 |
Neoplasm Metastasis
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 4.04 | 3 | 1 |
Cancer of Gastrointestinal Tract
[description not available] | 0 | 3.34 | 1 | 1 |
Bone Cancer
[description not available] | 0 | 1.95 | 1 | 0 |
Sarcoma, Epithelioid
[description not available] | 0 | 2.36 | 2 | 0 |
Bone Neoplasms
Tumors or cancer located in bone tissue or specific BONES. | 0 | 1.95 | 1 | 0 |
Sarcoma
A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant. | 0 | 7.36 | 2 | 0 |
Soft Tissue Neoplasms
Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc. | 0 | 1.95 | 1 | 0 |
Carcinoma, Anaplastic
[description not available] | 0 | 2.36 | 2 | 0 |
Lymph Node Metastasis
[description not available] | 0 | 1.95 | 1 | 0 |
Experimental Mammary Neoplasms
[description not available] | 0 | 1.95 | 1 | 0 |
Carcinoma
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer. | 0 | 2.36 | 2 | 0 |
Bladder Cancer
[description not available] | 0 | 1.98 | 1 | 0 |
Papilloma, Squamous Cell
[description not available] | 0 | 1.98 | 1 | 0 |
Condition, Preneoplastic
[description not available] | 0 | 1.98 | 1 | 0 |
Urinary Bladder Neoplasms
Tumors or cancer of the URINARY BLADDER. | 0 | 1.98 | 1 | 0 |
Carcinoma, Transitional Cell
A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS. | 0 | 1.98 | 1 | 0 |
Papilloma
A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed) | 0 | 1.98 | 1 | 0 |
Precancerous Conditions
Pathological conditions that tend eventually to become malignant. | 0 | 1.98 | 1 | 0 |
Leukemia P388
An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene. | 0 | 2.38 | 2 | 0 |
Cancer of Stomach
[description not available] | 0 | 1.96 | 1 | 0 |
Stomach Neoplasms
Tumors or cancer of the STOMACH. | 0 | 1.96 | 1 | 0 |
Dysembryoma
[description not available] | 0 | 1.96 | 1 | 0 |
Cancer of Testis
[description not available] | 0 | 1.96 | 1 | 0 |
Teratoma
A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642) | 0 | 1.96 | 1 | 0 |
Testicular Neoplasms
Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms. | 0 | 1.96 | 1 | 0 |
Leukemia L 1210
[description not available] | 0 | 2.37 | 2 | 0 |
Adenovirus Infections
[description not available] | 0 | 1.96 | 1 | 0 |
Human Adenovirus Infections
[description not available] | 0 | 1.96 | 1 | 0 |
Adenoviridae Infections
Virus diseases caused by the ADENOVIRIDAE. | 0 | 1.96 | 1 | 0 |
Adenovirus Infections, Human
Respiratory and conjunctival infections caused by 33 identified serotypes of human adenoviruses. | 0 | 1.96 | 1 | 0 |
Diffuse Mixed Small and Large Cell Lymphoma
[description not available] | 0 | 1.96 | 1 | 0 |
Lymphoma, Non-Hodgkin
Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease. | 0 | 1.96 | 1 | 0 |
Neoplasms, Nervous System
[description not available] | 0 | 1.96 | 1 | 0 |
Antidiuretic Hormone, Inappropriate Secretion
[description not available] | 0 | 1.96 | 1 | 0 |
Diarrhea
An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight. | 0 | 1.96 | 1 | 0 |
Hyponatremia
Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed) | 0 | 6.96 | 1 | 0 |
Inappropriate ADH Syndrome
A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced. | 0 | 1.96 | 1 | 0 |
Pleural Effusion
Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. | 0 | 1.96 | 1 | 0 |
Experimental Leukemia
[description not available] | 0 | 1.96 | 1 | 0 |
Cholera Infantum
[description not available] | 0 | 1.96 | 1 | 0 |
Cancer of Pancreas
[description not available] | 0 | 1.96 | 1 | 0 |
Thrombopenia
[description not available] | 0 | 2.37 | 2 | 0 |
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). | 0 | 1.96 | 1 | 0 |
Thrombocytopenia
A subnormal level of BLOOD PLATELETS. | 0 | 2.37 | 2 | 0 |
Bleeding
[description not available] | 0 | 1.96 | 1 | 0 |
Hemorrhage
Bleeding or escape of blood from a vessel. | 0 | 1.96 | 1 | 0 |