Page last updated: 2024-10-17

lactic acid and Neuroblastoma

lactic acid has been researched along with Neuroblastoma in 40 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"This study suggests that caffeic acid inhibits PHD2 enzyme activity which then activates the hypoxia-associated transcription factor HIF leading to a neuroprotective effect against hypoxia."8.12The novel prolyl hydroxylase-2 inhibitor caffeic acid upregulates hypoxia inducible factor and protects against hypoxia. ( Diao, A; Guo, B; Guo, Z; Hao, L; Li, L; Li, Y; Liu, Z; Yang, Y; Zhao, Q, 2022)
" The present study investigates the effects of ALCAR against the toxicity of 1-methyl-4-phenylpyridinium (MPP(+)), the neurotoxic metabolite of MPTP, in murine brain neuroblastoma cells."7.72Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells. ( Mazzio, E; Soliman, KF; Yoon, KJ, 2003)
"When neuroblastoma cells were transferred to a medium of low (6 nM) thiamine concentration, a 16-fold decrease in total intracellular thiamine content occurred within 8 days."7.69Thiamine deficiency in cultured neuroblastoma cells: effect on mitochondrial function and peripheral benzodiazepine receptors. ( Bettendorff, L; Bureau, M; Goessens, G; Grisar, T; Laschet, J; Sluse, F; Wins, P, 1995)
"NB2a/dl neuroblastoma cells were exposed to aluminum chloride or aluminum lactate (0."7.67Aluminum salts induce the accumulation of neurofilaments in perikarya of NB2a/dl neuroblastoma. ( Clarke, JF; Nixon, RA; Paskevich, PA; Shea, TB; Wheelock, TR, 1989)
"Neuroblastoma is the most common extracranial solid tumour of infancy."5.46Selective elimination of neuroblastoma cells by synergistic effect of Akt kinase inhibitor and tetrathiomolybdate. ( Beneš, P; Budková, Z; Jiráková, L; Karasová, M; Kohutková Lánová, M; Navrátilová, J; Pacherník, J; Šmarda, J, 2017)
"Hyperammonemia is a consistent finding in many metabolic disorders."5.31The effect of ammonium chloride on metabolism of primary neurons and neuroblastoma cells in vitro. ( Geraminegad, P; Haghighat, N; McCandless, DW, 2000)
"This study suggests that caffeic acid inhibits PHD2 enzyme activity which then activates the hypoxia-associated transcription factor HIF leading to a neuroprotective effect against hypoxia."4.12The novel prolyl hydroxylase-2 inhibitor caffeic acid upregulates hypoxia inducible factor and protects against hypoxia. ( Diao, A; Guo, B; Guo, Z; Hao, L; Li, L; Li, Y; Liu, Z; Yang, Y; Zhao, Q, 2022)
" The data show that MPP+ (500 μM) obstructs mitochondrial respiration/oxidative phosphorylation (OXPHOS) in mouse neuroblastoma Neuro-2a cells, juxtaposing accelerated glucose consumption and production of lactic acid."3.78Whole genome expression profile in neuroblastoma cells exposed to 1-methyl-4-phenylpyridine. ( Mazzio, E; Soliman, KF, 2012)
"The role of glutamine and alanine transport in the recycling of neurotransmitter glutamate was investigated in Guinea pig brain cortical tissue slices and prisms, and in cultured neuroblastoma and astrocyte cell lines."3.72Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation. ( Balcar, VJ; Bröer, A; Bröer, S; Bubb, WA; Conigrave, AD; Hare, N; McEwan, SR; McQuillan, JA; Rae, C, 2003)
" The present study investigates the effects of ALCAR against the toxicity of 1-methyl-4-phenylpyridinium (MPP(+)), the neurotoxic metabolite of MPTP, in murine brain neuroblastoma cells."3.72Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells. ( Mazzio, E; Soliman, KF; Yoon, KJ, 2003)
"When neuroblastoma cells were transferred to a medium of low (6 nM) thiamine concentration, a 16-fold decrease in total intracellular thiamine content occurred within 8 days."3.69Thiamine deficiency in cultured neuroblastoma cells: effect on mitochondrial function and peripheral benzodiazepine receptors. ( Bettendorff, L; Bureau, M; Goessens, G; Grisar, T; Laschet, J; Sluse, F; Wins, P, 1995)
"NB2a/dl neuroblastoma cells were exposed to aluminum chloride or aluminum lactate (0."3.67Aluminum salts induce the accumulation of neurofilaments in perikarya of NB2a/dl neuroblastoma. ( Clarke, JF; Nixon, RA; Paskevich, PA; Shea, TB; Wheelock, TR, 1989)
"Neuroblastoma is the most common extracranial solid tumour of infancy."1.46Selective elimination of neuroblastoma cells by synergistic effect of Akt kinase inhibitor and tetrathiomolybdate. ( Beneš, P; Budková, Z; Jiráková, L; Karasová, M; Kohutková Lánová, M; Navrátilová, J; Pacherník, J; Šmarda, J, 2017)
"Thiamine exhibited a lower IC50 value in both cell lines compared with DCA."1.40High-dose vitamin B1 reduces proliferation in cancer cell lines analogous to dichloroacetate. ( Berger, R; Hanberry, BS; Zastre, JA, 2014)
"Curcumin was encapsulated in biodegradable poly (lactide-co-glycolide) (PLGA) based-nanoparticulate formulation (Nps-Cur)."1.38Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line. ( Arseneault, M; Dao, L; Doggui, S; Ramassamy, C; Sahni, JK, 2012)
"Neuroblastoma is a common childhood cancer that often results in progressive minimal residual disease after primary tumor resection."1.37Immunostimulatory sutures that treat local disease recurrence following primary tumor resection. ( Intra, J; Salem, AK; Sandler, AD; Williams, RL; Zhang, XQ; Zhu, X, 2011)
"Furthermore, anaerobic metabolism in cancer cells bears similarity to homo-fermentative lactic acid bacteria, however very little is known about an alternative pathway that may drive adenosine triphosphate (ATP) production independent of glycolysis."1.36Evaluation of endogenous acidic metabolic products associated with carbohydrate metabolism in tumor cells. ( Mazzio, EA; Smith, B; Soliman, KF, 2010)
"Hyperammonemia is a consistent finding in many metabolic disorders."1.31The effect of ammonium chloride on metabolism of primary neurons and neuroblastoma cells in vitro. ( Geraminegad, P; Haghighat, N; McCandless, DW, 2000)
"The present studies were undertaken to determine the role of physiologically relevant concentrations of estrogens on amyloid-induced changes in cell viability, metabolic demands, and lipid peroxidation in response to the toxic fragment of beta-amyloid (betaAP 25-35)."1.30Low concentrations of estradiol reduce beta-amyloid (25-35)-induced toxicity, lipid peroxidation and glucose utilization in human SK-N-SH neuroblastoma cells. ( Green, PS; Gridley, KE; Simpkins, JW, 1997)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19905 (12.50)18.7374
1990's8 (20.00)18.2507
2000's6 (15.00)29.6817
2010's19 (47.50)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Guo, Z1
Yang, Y1
Li, L2
Zhao, Q1
Li, Y1
Liu, Z1
Hao, L1
Guo, B1
Diao, A1
Xu, Y1
Kusuyama, J1
Osana, S1
Matsuhashi, S1
Takada, H1
Inada, H1
Nagatomi, R1
Hanberry, BS1
Berger, R1
Zastre, JA2
Sweet, RL1
Marrache, S1
Pathak, RK1
Dhar, S1
Jeong, JH1
Kang, SH1
Kim, JH1
Yu, KS1
Lee, IH1
Lee, YJ1
Lee, JH1
Lee, NS1
Jeong, YG1
Kim, DK1
Kim, GH1
Lee, SH1
Hong, SK1
Han, SY1
Kang, BS1
Lee, J2
Jeong, EJ1
Lee, YK1
Kim, K2
Kwon, IC2
Lee, KY2
E, L1
Swerdlow, RH2
Min, HS1
You, DG1
Rhim, T1
Fornaguera, C1
Feiner-Gracia, N1
Calderó, G1
García-Celma, MJ1
Solans, C1
Navrátilová, J1
Karasová, M1
Kohutková Lánová, M1
Jiráková, L1
Budková, Z1
Pacherník, J1
Šmarda, J1
Beneš, P1
Smith, DJ1
Cossins, LR1
Hatzinisiriou, I1
Haber, M1
Nagley, P1
Mazzio, EA2
Smith, B1
Soliman, KF4
Deubzer, B2
Mayer, F1
Kuçi, Z2
Niewisch, M1
Merkel, G1
Handgretinger, R2
Bruchelt, G2
Levy, AG1
Zage, PE1
Akers, LJ1
Ghisoli, ML1
Chen, Z1
Fang, W1
Kannan, S1
Graham, T1
Zeng, L1
Franklin, AR1
Huang, P1
Zweidler-McKay, PA1
Intra, J1
Zhang, XQ1
Williams, RL1
Zhu, X1
Sandler, AD1
Salem, AK1
Boukli, N1
Rivera, N1
Doggui, S1
Sahni, JK1
Arseneault, M1
Dao, L1
Ramassamy, C1
Niewisch, MR1
Wolburg, H1
Sautter, M1
Krampen, L1
Mazzio, E2
Martins-Branco, D1
Esteves, AR1
Santos, D1
Arduino, DM1
Oliveira, CR1
Januario, C1
Cardoso, SM1
Wu, ZZ1
Wang, ZW1
Zhang, LG1
An, ZX1
Zhong, DH1
Huang, QP1
Luo, MR1
Liao, YJ1
Jin, L1
Li, CZ1
Kisaalita, WS1
Rae, C1
Hare, N1
Bubb, WA1
McEwan, SR1
Bröer, A1
McQuillan, JA1
Balcar, VJ1
Conigrave, AD1
Bröer, S1
Yoon, KJ1
GJESSING, LR1
Fonseca, CP1
Jones, JG1
Carvalho, RA1
Jeffrey, FM1
Montezinho, LP1
Geraldes, CF1
Castro, MM1
de Arriba, SG1
Stuchbury, G1
Yarin, J1
Burnell, J1
Loske, C1
Münch, G1
Chan, PH1
Kerlan, R1
Fishman, RA1
Moolenaar, WH1
Boonstra, J1
van der Saag, PT1
de Laat, SW1
Bettendorff, L1
Goessens, G1
Sluse, F1
Wins, P1
Bureau, M1
Laschet, J1
Grisar, T1
Häfeli, UO2
Sweeney, SM2
Beresford, BA2
Humm, JL1
Macklis, RM2
Flögel, U1
Willker, W1
Leibfritz, D1
Sim, EH1
Staub, F1
Mackert, B1
Kempski, O1
Peters, J1
Baethmann, A1
Partidos, CD1
Vohra, P1
Jones, D1
Farrar, G1
Steward, MW1
Gridley, KE1
Green, PS1
Simpkins, JW1
Fall, CP1
Bennett, JP1
Haghighat, N1
McCandless, DW1
Geraminegad, P1
Shea, TB1
Clarke, JF1
Wheelock, TR1
Paskevich, PA1
Nixon, RA1
Pauwels, PJ1
Opperdoes, FR1
Trouet, A1

Other Studies

40 other studies available for lactic acid and Neuroblastoma

ArticleYear
The novel prolyl hydroxylase-2 inhibitor caffeic acid upregulates hypoxia inducible factor and protects against hypoxia.
    European journal of pharmacology, 2022, Nov-05, Volume: 934

    Topics: Animals; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Prolin

2022
Lactate promotes neuronal differentiation of SH-SY5Y cells by lactate-responsive gene sets through NDRG3-dependent and -independent manners.
    The Journal of biological chemistry, 2023, Volume: 299, Issue:6

    Topics: Animals; Cell Differentiation; Cell Line; Gene Expression Regulation; Humans; Intracellular Signalin

2023
High-dose vitamin B1 reduces proliferation in cancer cell lines analogous to dichloroacetate.
    Cancer chemotherapy and pharmacology, 2014, Volume: 73, Issue:3

    Topics: Caspase 3; Cell Line, Tumor; Cell Proliferation; Dichloroacetic Acid; Glucose; Humans; Lactic Acid;

2014
HIF1-α-mediated gene expression induced by vitamin B1 deficiency.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2013, Volume: 83, Issue:3

    Topics: Cell Hypoxia; Cell Nucleus; Gene Expression; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid;

2013
Detouring of cisplatin to access mitochondrial genome for overcoming resistance.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jul-22, Volume: 111, Issue:29

    Topics: Animals; Brain; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Energy Metabolism; Genome, M

2014
Protective effects of poly(lactic-co-glycolic acid) nanoparticles loaded with erythropoietin stabilized by sodium cholate against glutamate-induced neurotoxicity.
    Journal of nanoscience and nanotechnology, 2014, Volume: 14, Issue:11

    Topics: Cell Line, Tumor; Cell Survival; Drug Stability; Erythropoietin; Glutamic Acid; Humans; Lactic Acid;

2014
Optical Imaging and Gene Therapy with Neuroblastoma-Targeting Polymeric Nanoparticles for Potential Theranostic Applications.
    Small (Weinheim an der Bergstrasse, Germany), 2016, Mar-02, Volume: 12, Issue:9

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Gene Silencing; Genetic Therapy; Humans; Lactic Ac

2016
Lactate's effect on human neuroblastoma cell bioenergetic fluxes.
    Biochemical pharmacology, 2016, Jan-01, Volume: 99

    Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Energy Metabolism; Humans; Lactic Acid; Neurobla

2016
Theranostic gas-generating nanoparticles for targeted ultrasound imaging and treatment of neuroblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2016, Feb-10, Volume: 223

    Topics: Animals; Antineoplastic Agents; Calcium Carbonate; Carbon Dioxide; Cell Line, Tumor; Cell Survival;

2016
PLGA nanoparticles from nano-emulsion templating as imaging agents: Versatile technology to obtain nanoparticles loaded with fluorescent dyes.
    Colloids and surfaces. B, Biointerfaces, 2016, Nov-01, Volume: 147

    Topics: Cell Proliferation; Drug Carriers; Emulsions; Fluorescent Dyes; HeLa Cells; Humans; Lactic Acid; Nan

2016
Selective elimination of neuroblastoma cells by synergistic effect of Akt kinase inhibitor and tetrathiomolybdate.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:9

    Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; Cell Respiration; Down-Regulation; Fibroblasts; G

2017
Lack of correlation between MYCN expression and the Warburg effect in neuroblastoma cell lines.
    BMC cancer, 2008, Sep-14, Volume: 8

    Topics: Adenosine Triphosphate; Cell Line, Tumor; Gene Amplification; Genes, myc; Glycolysis; Humans; Lactic

2008
Evaluation of endogenous acidic metabolic products associated with carbohydrate metabolism in tumor cells.
    Cell biology and toxicology, 2010, Volume: 26, Issue:3

    Topics: Acids; Aerobiosis; Alcohols; Aldehydes; Amino Acids; Anaerobiosis; Cell Line, Tumor; Fermentation; G

2010
H(2)O(2)-mediated cytotoxicity of pharmacologic ascorbate concentrations to neuroblastoma cells: potential role of lactate and ferritin.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2010, Volume: 25, Issue:6

    Topics: Ascorbic Acid; Cell Line, Tumor; Cytotoxins; Ferritins; Humans; Hydrogen Peroxide; Lactic Acid; Neur

2010
The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma.
    Investigational new drugs, 2012, Volume: 30, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy P

2012
Immunostimulatory sutures that treat local disease recurrence following primary tumor resection.
    Biomedical materials (Bristol, England), 2011, Volume: 6, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Biocompatible Materials; Cell Line, Tumor; Delayed-Action Preparati

2011
Pericellular pH homeostasis is a primary function of the Warburg effect: inversion of metabolic systems to control lactate steady state in tumor cells.
    Cancer science, 2012, Volume: 103, Issue:3

    Topics: Animals; Blotting, Western; Cell Line, Tumor; Chromatography, High Pressure Liquid; DNA Fingerprinti

2012
Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 30, Issue:2

    Topics: Antioxidants; Cell Line, Tumor; Curcumin; Glutathione; Humans; Lactic Acid; Microscopy, Electron, Tr

2012
Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy?
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012, Volume: 29, Issue:3-4

    Topics: Acetyl Coenzyme A; Apoptosis; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Culture Media

2012
Whole genome expression profile in neuroblastoma cells exposed to 1-methyl-4-phenylpyridine.
    Neurotoxicology, 2012, Volume: 33, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure

2012
Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness?
    Experimental neurology, 2012, Volume: 238, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Case-Control Studies; Cell Line,

2012
Responsiveness of voltage-gated calcium channels in SH-SY5Y human neuroblastoma cells on quasi-three-dimensional micropatterns formed with poly (l-lactic acid).
    International journal of nanomedicine, 2013, Volume: 8

    Topics: Analysis of Variance; Bioengineering; Calcium Channels, L-Type; Cell Culture Techniques; Cell Line,

2013
Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation.
    Journal of neurochemistry, 2003, Volume: 85, Issue:2

    Topics: Acetic Acid; Alanine; Animals; Astrocytes; beta-Alanine; Biological Transport; Carbon Isotopes; Cell

2003
Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells.
    Biochemical pharmacology, 2003, Jul-15, Volume: 66, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acetylcarnitine; Adenosin

2003
STUDIES OF FUNCTIONAL NEURAL TUMORS. V. URINARY EXCRETION OF 3-METHOXY-4HYDROXYPHENYL-LACTIC ACID.
    Scandinavian journal of clinical and laboratory investigation, 1963, Volume: 15

    Topics: Acetates; Adrenal Gland Neoplasms; Butyrates; Carcinoid Tumor; Child; Chromatography; Dihydroxypheny

1963
Tricarboxylic acid cycle inhibition by Li+ in the human neuroblastoma SH-SY5Y cell line: a 13C NMR isotopomer analysis.
    Neurochemistry international, 2005, Volume: 47, Issue:6

    Topics: Acetyl Coenzyme A; Antimanic Agents; Bipolar Disorder; Brain; Brain Chemistry; Carbon Isotopes; Cell

2005
Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers.
    Neurobiology of aging, 2007, Volume: 28, Issue:7

    Topics: Adenosine Triphosphate; Analysis of Variance; Cell Line, Tumor; Dose-Response Relationship, Drug; En

2007
Intracellular volume of osmotically regulated C-6 glioma cells.
    Journal of neuroscience research, 1982, Volume: 8, Issue:1

    Topics: Animals; Cell Line; Extracellular Space; Glioma; Hybrid Cells; Lactates; Lactic Acid; Mice; Neurobla

1982
Sodium/proton exchange in mouse neuroblastoma cells.
    The Journal of biological chemistry, 1981, Dec-25, Volume: 256, Issue:24

    Topics: Amiloride; Animals; Anions; Biological Transport, Active; Cell Line; Hydrogen-Ion Concentration; Ion

1981
Thiamine deficiency in cultured neuroblastoma cells: effect on mitochondrial function and peripheral benzodiazepine receptors.
    Journal of neurochemistry, 1995, Volume: 64, Issue:5

    Topics: Adenosine Triphosphate; Amprolium; Animals; Cell Death; Culture Media; Isoquinolines; Lactates; Lact

1995
Effective targeting of magnetic radioactive 90Y-microspheres to tumor cells by an externally applied magnetic field. Preliminary in vitro and in vivo results.
    Nuclear medicine and biology, 1995, Volume: 22, Issue:2

    Topics: Animals; Cell Line; Cell Survival; Culture Techniques; Dose-Response Relationship, Radiation; Female

1995
Regulation of intracellular pH in neuronal and glial tumour cells, studied by multinuclear NMR spectroscopy.
    NMR in biomedicine, 1994, Volume: 7, Issue:4

    Topics: Animals; Basement Membrane; Biological Transport; Glioma; Hydrogen-Ion Concentration; Intracellular

1994
Magnetically directed poly(lactic acid) 90Y-microspheres: novel agents for targeted intracavitary radiotherapy.
    Journal of biomedical materials research, 1994, Volume: 28, Issue:8

    Topics: Animals; Brachytherapy; Electromagnetic Fields; Ferrosoferric Oxide; Iron; Lactates; Lactic Acid; Mi

1994
Swelling and death of neuronal cells by lactic acid.
    Journal of the neurological sciences, 1993, Volume: 119, Issue:1

    Topics: Animals; Cell Death; Culture Media; Flow Cytometry; Hydrogen-Ion Concentration; Lactates; Lactic Aci

1993
CTL responses induced by a single immunization with peptide encapsulated in biodegradable microparticles.
    Journal of immunological methods, 1997, Aug-07, Volume: 206, Issue:1-2

    Topics: Amino Acid Sequence; Animals; Antigen Presentation; Carrier Proteins; Dose-Response Relationship, Im

1997
Low concentrations of estradiol reduce beta-amyloid (25-35)-induced toxicity, lipid peroxidation and glucose utilization in human SK-N-SH neuroblastoma cells.
    Brain research, 1997, Dec-05, Volume: 778, Issue:1

    Topics: Amyloid beta-Peptides; Dose-Response Relationship, Drug; Estradiol; Glucose; Humans; Lactic Acid; Li

1997
Characterization and time course of MPP+ -induced apoptosis in human SH-SY5Y neuroblastoma cells.
    Journal of neuroscience research, 1999, Mar-01, Volume: 55, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Cell Cycle; Cell Membrane; Cell Nucleus; DNA Fragmentation;

1999
The effect of ammonium chloride on metabolism of primary neurons and neuroblastoma cells in vitro.
    Metabolic brain disease, 2000, Volume: 15, Issue:2

    Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Brain; Cell Death; Energy Metabolism; Female; Fe

2000
Aluminum salts induce the accumulation of neurofilaments in perikarya of NB2a/dl neuroblastoma.
    Brain research, 1989, Jul-17, Volume: 492, Issue:1-2

    Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Cell Line; Chlorides; Cytoskeleton; Interm

1989
Effects of antimycin, glucose deprivation, and serum on cultures of neurons, astrocytes, and neuroblastoma cells.
    Journal of neurochemistry, 1985, Volume: 44, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antimycin A; Astrocytes; Blood; Cell Line; Cells, Cultured; Glucose

1985