metoclopramide has been researched along with Neuroblastoma in 3 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of metoclopramide (MCP) and bromocriptine (BC) on the growth of neuroblastoma (NB) cells and their influence on the plasma membrane binding of several neurotransmitters were studied." | 7.68 | Influence of metoclopramide and bromocriptine upon the growth of human and murine neuroblastoma cells. ( Bartsch, O; Busse, E; Kornhuber, B; Schneider, A, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Appadu, BL | 1 |
| Lambert, DG | 1 |
| Malone, HM | 1 |
| Peters, JA | 1 |
| Lambert, JJ | 1 |
| Busse, E | 1 |
| Bartsch, O | 1 |
| Schneider, A | 1 |
| Kornhuber, B | 1 |
3 other studies available for metoclopramide and Neuroblastoma
| Article | Year |
|---|---|
Analgesia induced by metoclopramide.
Topics: Analgesia; Humans; Metoclopramide; Neuroblastoma; Receptors, Opioid; Tumor Cells, Cultured | 1993 |
Physiological and pharmacological properties of 5-HT3 receptors--a patch clamp-study.
Topics: Action Potentials; Animals; Cocaine; Ganglia; Guinea Pigs; Imidazoles; Ion Channels; Ketamine; Metoc | 1991 |
Influence of metoclopramide and bromocriptine upon the growth of human and murine neuroblastoma cells.
Topics: Animals; Blood Cell Count; Bromocriptine; Copper; Female; Metoclopramide; Mice; Neuroblastoma; Neuro | 1990 |