antillatoxin and Neuroblastoma

antillatoxin has been researched along with Neuroblastoma* in 1 studies

Other Studies

1 other study(ies) available for antillatoxin and Neuroblastoma

Article	Year
Antillatoxin B, a neurotoxic lipopeptide from the marine cyanobacterium Lyngbya majuscula. Journal of natural products, 2001, Volume: 64, Issue:7 Bioassay-guided fractionation of organic extracts from two Lyngbya majuscula collections led to the isolation of a new secondary metabolite, antillatoxin B, an unusual N-methyl homophenylalanine analogue of the potent neurotoxin antillatoxin. Its structure was deduced from 2D NMR and data comparisons with antillatoxin. Antillatoxin B exhibited significant sodium channel-activating (EC(50) = 1.77 microM) and ichthyotoxic (LC(50) = 1 microM) properties. Topics: Animals; Chromatography, High Pressure Liquid; Cyanobacteria; Goldfish; Lipopeptides; Lipoproteins; Lyngbya Toxins; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Neuroblastoma; Peptides, Cyclic; Sodium Channels; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured	2001

Article

Year

Antillatoxin B, a neurotoxic lipopeptide from the marine cyanobacterium Lyngbya majuscula.

Journal of natural products, 2001, Volume: 64, Issue:7

Bioassay-guided fractionation of organic extracts from two Lyngbya majuscula collections led to the isolation of a new secondary metabolite, antillatoxin B, an unusual N-methyl homophenylalanine analogue of the potent neurotoxin antillatoxin. Its structure was deduced from 2D NMR and data comparisons with antillatoxin. Antillatoxin B exhibited significant sodium channel-activating (EC(50) = 1.77 microM) and ichthyotoxic (LC(50) = 1 microM) properties.

Topics: Animals; Chromatography, High Pressure Liquid; Cyanobacteria; Goldfish; Lipopeptides; Lipoproteins; Lyngbya Toxins; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Neuroblastoma; Peptides, Cyclic; Sodium Channels; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured

2001