n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine has been researched along with Neuroblastoma in 6 studies
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine: a zinc ion chelating agent; structure given in first source
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine : An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (33.33) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 2 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ohkubo, M | 1 |
Miyamoto, A | 1 |
Shiraishi, M | 1 |
Matias, AC | 1 |
Manieri, TM | 1 |
Cerchiaro, G | 1 |
Sakabe, I | 1 |
Paul, S | 1 |
Dansithong, W | 1 |
Shinozawa, T | 1 |
Adler, M | 1 |
Shafer, H | 1 |
Hamilton, T | 1 |
Petrali, JP | 1 |
Ho, LH | 1 |
Ratnaike, RN | 1 |
Zalewski, PD | 1 |
Ahn, YH | 1 |
Koh, JY | 1 |
Hong, SH | 1 |
6 other studies available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and Neuroblastoma
Article | Year |
---|---|
Heavy metal chelator TPEN attenuates fura-2 fluorescence changes induced by cadmium, mercury and methylmercury.
Topics: Boron Compounds; Cadmium Poisoning; Calcium; Calcium Channel Blockers; Cell Line, Tumor; Chelating A | 2016 |
Zinc Chelation Mediates the Lysosomal Disruption without Intracellular ROS Generation.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Survival | 2016 |
Induction of apoptosis in Neuro-2A cells by Zn2+ chelating.
Topics: Animals; Apoptosis; Cell Division; Cell Nucleus; Chelating Agents; Copper; DNA Fragmentation; Dose-R | 1998 |
Cytotoxic actions of the heavy metal chelator TPEN on NG108-15 neuroblastoma-glioma cells.
Topics: Animals; Apoptosis; Biomarkers; Cell Aggregation; Cell Nucleus; Cell Survival; Chelating Agents; Chr | 1999 |
Involvement of intracellular labile zinc in suppression of DEVD-caspase activity in human neuroblastoma cells.
Topics: Alzheimer Disease; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Chelating Agents; Coumarins; | 2000 |
Protein synthesis-dependent but Bcl-2-independent cytochrome C release in zinc depletion-induced neuronal apoptosis.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Cytochrome c Group; | 2000 |