acetaminophen has been researched along with Neuroblastoma in 6 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with relapsed/refractory stage 4 high-risk neuroblastoma were enrolled on a phase I study (NANT2004-03) of intravenous fenretinide emulsion." | 9.19 | Probable fatal drug interaction between intravenous fenretinide, ceftriaxone, and acetaminophen: a case report from a New Approaches to Neuroblastoma (NANT) Phase I study. ( Ames, MM; Czarnecki, S; Glade Bender, JL; Groshen, S; Kang, MH; Marachelian, A; Matthay, KK; Maurer, BJ; Reynolds, CP; Sposto, R; Villablanca, JG, 2014) |
| "Acetaminophen potentiates staurosporine-mediated neuroblastoma cell death." | 7.74 | Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line. ( Ceña, V; Posadas, I; Prieto-Lloret, J; Santos, P; Vellecco, V, 2007) |
| "Patients with relapsed/refractory stage 4 high-risk neuroblastoma were enrolled on a phase I study (NANT2004-03) of intravenous fenretinide emulsion." | 5.19 | Probable fatal drug interaction between intravenous fenretinide, ceftriaxone, and acetaminophen: a case report from a New Approaches to Neuroblastoma (NANT) Phase I study. ( Ames, MM; Czarnecki, S; Glade Bender, JL; Groshen, S; Kang, MH; Marachelian, A; Matthay, KK; Maurer, BJ; Reynolds, CP; Sposto, R; Villablanca, JG, 2014) |
| "Acetaminophen potentiates staurosporine-mediated neuroblastoma cell death." | 3.74 | Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line. ( Ceña, V; Posadas, I; Prieto-Lloret, J; Santos, P; Vellecco, V, 2007) |
| "Acetophenetidines, acetamidophenols, phenetidines and aminophenols substituted in o-, m- or p-position inhibit prostaglandin-synthetases originating from C 1300 mouse neuroblastoma cells (clone N2A), rat astrocytoma cells (clone C 6) and rat renal medulla." | 3.66 | Inhibition of prostaglandin synthetases derived from neuronal and glial cells and rat renal medulla by ortho-, meta- and para-substituted aminophenolic compounds. ( Baumann, J; von Bruchhausen, F; Wurm, G, 1983) |
| "The inhibitory actions of phenacetin and paracetamol and of their desacetylation products on prostaglandin synthesis were studied on enzyme preparations originating from a neuronal cell line (mouse neuroblastoma, clone N2A), a glial cell line (rat astrocytoma, clone C6) and rat renal medulla." | 3.66 | Inhibitory actions of desacetylation products of phenacetin and paracetamol on prostaglandin synthetases in neuronal and glial cell lines and rat renal medulla. ( Baumann, J; von Bruchlausen, F, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Deubzer, HE | 3 |
| Astrahantseff, K | 3 |
| Lodrini, M | 3 |
| Kang, MH | 1 |
| Villablanca, JG | 1 |
| Glade Bender, JL | 1 |
| Matthay, KK | 1 |
| Groshen, S | 1 |
| Sposto, R | 1 |
| Czarnecki, S | 1 |
| Ames, MM | 1 |
| Reynolds, CP | 1 |
| Marachelian, A | 1 |
| Maurer, BJ | 1 |
| Posadas, I | 2 |
| Santos, P | 2 |
| Ceña, V | 2 |
| Vellecco, V | 1 |
| Prieto-Lloret, J | 1 |
| Baumann, J | 2 |
| von Bruchhausen, F | 1 |
| Wurm, G | 1 |
| von Bruchlausen, F | 1 |
1 trial available for acetaminophen and Neuroblastoma
| Article | Year |
|---|---|
Probable fatal drug interaction between intravenous fenretinide, ceftriaxone, and acetaminophen: a case report from a New Approaches to Neuroblastoma (NANT) Phase I study.
Topics: Acetaminophen; Ceftriaxone; Child; Dose-Response Relationship, Drug; Drug Interactions; Fatal Outcom | 2014 |
5 other studies available for acetaminophen and Neuroblastoma
| Article | Year |
|---|---|
A Deep Dive into the Circulating ctDNA Cosmos to Vanquish Neuroblastoma.
Topics: Acetaminophen; Aspirin; Cell-Free Nucleic Acids; Circulating Tumor DNA; Genomics; Humans; Neuroblast | 2022 |
A Deep Dive into the Circulating ctDNA Cosmos to Vanquish Neuroblastoma.
Topics: Acetaminophen; Aspirin; Cell-Free Nucleic Acids; Circulating Tumor DNA; Genomics; Humans; Neuroblast | 2022 |
A Deep Dive into the Circulating ctDNA Cosmos to Vanquish Neuroblastoma.
Topics: Acetaminophen; Aspirin; Cell-Free Nucleic Acids; Circulating Tumor DNA; Genomics; Humans; Neuroblast | 2022 |
A Deep Dive into the Circulating ctDNA Cosmos to Vanquish Neuroblastoma.
Topics: Acetaminophen; Aspirin; Cell-Free Nucleic Acids; Circulating Tumor DNA; Genomics; Humans; Neuroblast | 2022 |
Acetaminophen induces human neuroblastoma cell death through NFKB activation.
Topics: Acetaminophen; Active Transport, Cell Nucleus; Analysis of Variance; bcl-2-Associated X Protein; Blo | 2012 |
Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line.
Topics: Acetaminophen; Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell S | 2007 |
Inhibition of prostaglandin synthetases derived from neuronal and glial cells and rat renal medulla by ortho-, meta- and para-substituted aminophenolic compounds.
Topics: Acetaminophen; Aminophenols; Animals; Aspirin; Astrocytoma; Cell Line; Clone Cells; Cyclooxygenase I | 1983 |
Inhibitory actions of desacetylation products of phenacetin and paracetamol on prostaglandin synthetases in neuronal and glial cell lines and rat renal medulla.
Topics: Acetaminophen; Aminophenols; Animals; Astrocytoma; Cell Line; Cyclooxygenase Inhibitors; In Vitro Te | 1982 |