glutamine and Neuroblastoma

glutamine has been researched along with Neuroblastoma in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19905 (16.13)18.7374
1990's3 (9.68)18.2507
2000's10 (32.26)29.6817
2010's11 (35.48)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Abdrakhmanov, A; Gogvadze, V; Maximchik, P; Senichkin, V; Valter, K; Zhivotovsky, B1
Dubrovska, A; Kamili, A; Kavallaris, M; Le Grand, M; Mukha, A; Püschel, J; Valli, E; Vittorio, O1
Chen, X; Davidoff, AM; Lian, G; Liu, L; Shah, N; Shen, Y; Wang, R; Wang, T; Yang, J1
Bandyopadhyay, TK; Mondal, A; Paul, T1
Mödl, B; Moldzio, R; Pohl, EE; Rupprecht, A1
Gan, L; Liu, H; Qing, G; Ren, P; Xiao, D; Xiu, R; Yue, M1
Freeman, KW; Mary-Sinclair, MN; Olsen, RR; Yin, Z1
Gautschi, M; Häberle, J; Hahn, D; Hu, L; Laemmle, A; Leibundgut, K; Nuoffer, JM; Rüfenacht, V1
Lu, Z; Tong, X; Wei, F; Yang, J; Zhang, Y; Zhang, Z; Zhao, S1
Hu, Y; Liu, H; Qing, G; Ren, P; Su, H; Xiao, D; Xiu, R; Yue, M1
Abid, MN; Amin, FU; Khan, M; Kim, MO; Kim, MW; Kim, TH; Rehman, SU; Shah, SA1
Krewenka, C; Moldzio, R; Pohl, EE; Vazdar, K; Zimmermann, L1
Hogarty, MD; Li, B; Liu, X; Maris, JM; Mayes, PA; Qing, G; Simon, MC; Skuli, N; Thompson, CB; Vu, A; Walton, ZE; Wise, DR1
Balcar, VJ; Bröer, A; Bröer, S; Bubb, WA; Conigrave, AD; Hare, N; McEwan, SR; McQuillan, JA; Rae, C1
Arun, P; Hershfield, JR; Madhavarao, CN; Moffett, JR; Namboodiri, MA1
Fukuzawa, M; Soh, H; Wang, HS; Wasa, M1
Arun, P; Madhavarao, CN; Moffett, JR; Namboodiri, MA1
Fukuzawa, M; Soh, H; Wasa, M1
Goto, H; Izaki, S; Yokota, S1
Chaudhary, KD; Lacoste, L; Lapointe, J1
Burrows, H; Cohen, JS; Navon, G1
Chang, B; Han, G; Moore, T; Samid, D; Shack, S; Sidell, N; Wada, R1
Furutama, D; Kimura, F; Nakagawa, T; Nakajima, H; Ohsawa, N; Shimizu, A; Shinoda, K1
Borchelt, DR; Cooper, JK; Dawson, TM; Dawson, VL; Delanoy, M; Herring, WJ; Kaminsky, Z; Khan, FA; Masone, J; Peters, MF; Ross, CA; Schilling, G; Sharp, AH1
Okada, A; Tazuke, Y; Wang, HS; Wasa, M1
Okada, A; Wang, HS; Wasa, M3
Canellakis, ES; Chen, KY1
Hertz, L; Lacoste, L; Lapointe, J1
Becker, MA; Minna, JD; Seegmiller, JE; Wood, AW1

Reviews

1 review(s) available for glutamine and Neuroblastoma

ArticleYear
Isolation, Purification, Characterisation and Application of L-ASNase: A Review.
    Recent patents on biotechnology, 2019, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Asparaginase; Asparagine; Escherichia coli; Glutamine; Humans; Neuroblastoma; Patents as Topic; Pectobacterium carotovorum

2019

Other Studies

30 other study(ies) available for glutamine and Neuroblastoma

ArticleYear
Distinct effects of etoposide on glutamine-addicted neuroblastoma.
    Cellular and molecular life sciences : CMLS, 2020, Volume: 77, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Etoposide; Glutamine; Glutathione; Humans; Mitochondria; Neuroblastoma; Oxidative Stress; Oxygen Consumption

2020
Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation.
    Theranostics, 2020, Volume: 10, Issue:14

    Topics: Cell Line, Tumor; DNA Repair; Gene Expression Regulation, Neoplastic; Genes, myc; Glutamine; Humans; N-Myc Proto-Oncogene Protein; Neoplastic Stem Cells; Neuroblastoma; Radiotherapy

2020
MYCN drives glutaminolysis in neuroblastoma and confers sensitivity to an ROS augmenting agent.
    Cell death & disease, 2018, 02-14, Volume: 9, Issue:2

    Topics: Acetylcysteine; Allografts; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Child; Dimethyl Fumarate; Drug Screening Assays, Antitumor; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glutamine; Glycolysis; Humans; Mice; N-Myc Proto-Oncogene Protein; Neural Crest; Neuroblastoma; Neurons; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction

2018
Glutamine regulates mitochondrial uncoupling protein 2 to promote glutaminolysis in neuroblastoma cells.
    Biochimica et biophysica acta. Bioenergetics, 2019, 05-01, Volume: 1860, Issue:5

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Energy Metabolism; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Mice; Neoplasm Proteins; Neuroblastoma; Uncoupling Protein 2

2019
ATF4 and N-Myc coordinate glutamine metabolism in MYCN-amplified neuroblastoma cells through ASCT2 activation.
    The Journal of pathology, 2015, Volume: 235, Issue:1

    Topics: Activating Transcription Factor 4; Amino Acid Transport System ASC; Cell Line, Tumor; Cell Proliferation; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, myc; Glutamine; Humans; Minor Histocompatibility Antigens; Neuroblastoma; Prognosis

2015
Antagonizing Bcl-2 family members sensitizes neuroblastoma and Ewing's sarcoma to an inhibitor of glutamine metabolism.
    PloS one, 2015, Volume: 10, Issue:1

    Topics: Aniline Compounds; Animals; Antimetabolites, Antineoplastic; Apoptosis; Bone Neoplasms; Caspases; Cell Line, Tumor; Cell Proliferation; Diazooxonorleucine; Drug Synergism; Glutamine; Humans; Mice; Neuroblastoma; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Sarcoma, Ewing; Sulfonamides; Xenograft Model Antitumor Assays

2015
Fatal hyperammonemia and carbamoyl phosphate synthetase 1 (CPS1) deficiency following high-dose chemotherapy and autologous hematopoietic stem cell transplantation.
    Molecular genetics and metabolism, 2015, Volume: 114, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Edema; Carbamoyl-Phosphate Synthase (Ammonia); Carbamyl Phosphate; Carboplatin; Child, Preschool; Combined Modality Therapy; Etoposide; Fatal Outcome; Glutamine; Hematopoietic Stem Cell Transplantation; Hep G2 Cells; Humans; Hyperammonemia; Liver; Male; Middle Aged; Neuroblastoma; Ornithine Carbamoyltransferase; Oxidative Phosphorylation

2015
Heat shock protein 70 induction by glutamine increases the α-synuclein degradation in SH-SY5Y neuroblastoma cells.
    Molecular medicine reports, 2015, Volume: 12, Issue:4

    Topics: alpha-Synuclein; Cell Line, Tumor; DNA-Binding Proteins; Gene Expression Regulation; Glutamine; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; Humans; Neuroblastoma; Proteolysis; Transcription Factors; Up-Regulation

2015
Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2.
    Oncotarget, 2015, Dec-01, Volume: 6, Issue:38

    Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Chromatin Immunoprecipitation; Enzyme Activation; Glutaminase; Glutamine; Glycolysis; Humans; Hydrolysis; Immunoenzyme Techniques; Mice; Mice, Inbred NOD; Mice, SCID; Neuroblastoma; Proto-Oncogene Proteins c-myc; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2015
Anthocyanins abrogate glutamate-induced AMPK activation, oxidative stress, neuroinflammation, and neurodegeneration in postnatal rat brain.
    Journal of neuroinflammation, 2016, 11-08, Volume: 13, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Animals, Newborn; Anthocyanins; Antioxidants; Cell Line, Transformed; Cyclooxygenase 2; Encephalitis; Enzyme Activation; Gene Expression Regulation, Developmental; Glutamine; Humans; Nerve Degeneration; Neuroblastoma; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction

2016
Nutrient deprivation in neuroblastoma cells alters 4-hydroxynonenal-induced stress response.
    Oncotarget, 2017, Jan-31, Volume: 8, Issue:5

    Topics: Aldehydes; Animals; Cell Line, Tumor; Cell Shape; Cell Survival; Energy Metabolism; Glucose; Glutamine; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neuroblastoma; Oxidation-Reduction; Oxidative Stress; Time Factors

2017
ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation.
    Cancer cell, 2012, Nov-13, Volume: 22, Issue:5

    Topics: Activating Transcription Factor 4; Aminooxyacetic Acid; Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Caspases; Cell Cycle Proteins; Cell Proliferation; Glutamine; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neuroblastoma; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Repressor Proteins; Tumor Suppressor Protein p53

2012
Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation.
    Journal of neurochemistry, 2003, Volume: 85, Issue:2

    Topics: Acetic Acid; Alanine; Animals; Astrocytes; beta-Alanine; Biological Transport; Carbon Isotopes; Cell Compartmentation; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Humans; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Neuroblastoma; Rats

2003
SH-SY5Y neuroblastoma cells: a model system for studying biosynthesis of NAAG.
    Neuroreport, 2004, May-19, Volume: 15, Issue:7

    Topics: Cell Line, Tumor; Dipeptides; Glutamine; Humans; Neuroblastoma

2004
Glutamine regulates amino acid transport and glutathione levels in a human neuroblastoma cell line.
    Pediatric surgery international, 2005, Volume: 21, Issue:1

    Topics: Amino Acids; Biological Transport, Active; Cell Division; DNA, Neoplasm; Glutamine; Glutathione; Humans; In Vitro Techniques; Neuroblastoma; Tumor Cells, Cultured

2005
Regulation of N-acetylaspartate and N-acetylaspartylglutamate biosynthesis by protein kinase activators.
    Journal of neurochemistry, 2006, Volume: 98, Issue:6

    Topics: Aspartic Acid; Bucladesine; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Dipeptides; Dose-Response Relationship, Drug; Enzyme Activation; Glutamine; Humans; Neuroblastoma; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Time Factors

2006
Hypoxia upregulates amino acid transport in a human neuroblastoma cell line.
    Journal of pediatric surgery, 2007, Volume: 42, Issue:4

    Topics: Amino Acids; Biological Transport; Cell Hypoxia; Cycloheximide; Dactinomycin; Glutamic Acid; Glutamine; Humans; Hypoxia; Leucine; Neuroblastoma; Protein Synthesis Inhibitors; Tumor Cells, Cultured; Up-Regulation

2007
Increased chemosensitivity and elevated reactive oxygen species are mediated by glutathione reduction in glutamine deprived neuroblastoma cells.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Glutamine; Glutathione; Humans; Melphalan; Neuroblastoma; Oxidation-Reduction; Reactive Oxygen Species

2008
Derepression of the glutamine synthetase in neuroblastoma cells at low concentrations of glutamine.
    Journal of neurochemistry, 1982, Volume: 39, Issue:1

    Topics: Animals; Cell Line; Culture Media; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Mice; Neuroblastoma; Neuroglia; Neurons; Rats

1982
Differences in metabolite levels upon differentiation of intact neuroblastoma X glioma cells observed by proton NMR spectroscopy.
    FEBS letters, 1983, Oct-17, Volume: 162, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Glioma; Glutamine; Hybrid Cells; Magnetic Resonance Spectroscopy; Mice; Neuroblastoma; Peptides; Prostaglandins E; Protein Sorting Signals; Protons; Rats; Theophylline

1983
Phenylacetate synergizes with retinoic acid in inducing the differentiation of human neuroblastoma cells.
    International journal of cancer, 1995, Feb-08, Volume: 60, Issue:4

    Topics: Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Genes, myc; Glutamine; Humans; Immunoenzyme Techniques; Neurites; Neuroblastoma; Phenylacetates; Protein Prenylation; Proto-Oncogene Proteins c-myc; Receptors, Retinoic Acid; Tretinoin; Tumor Cells, Cultured; Up-Regulation

1995
Transcriptional activation by the androgen receptor in X-linked spinal and bulbar muscular atrophy.
    Journal of the neurological sciences, 1996, Volume: 142, Issue:1-2

    Topics: Animals; Base Sequence; Binding, Competitive; Blotting, Western; Choline O-Acetyltransferase; COS Cells; Gene Expression Regulation; Genetic Linkage; Glutamine; Hybrid Cells; Metribolone; Mice; Molecular Sequence Data; Muscular Atrophy, Spinal; Mutagenesis; Neuroblastoma; Receptors, Androgen; Repetitive Sequences, Nucleic Acid; Testosterone Congeners; Transcription, Genetic; X Chromosome

1996
Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.
    Human molecular genetics, 1998, Volume: 7, Issue:5

    Topics: Animals; Cell Line; Cell Nucleus; Glutamine; Humans; Huntingtin Protein; Huntington Disease; Kidney; Mice; Nerve Tissue Proteins; Neuroblastoma; Nuclear Proteins; Peptide Fragments; Repetitive Sequences, Nucleic Acid; Staurosporine; Transfection; Tumor Cells, Cultured

1998
Insulin-like growth factor-I stimulates amino acid transport in a glutamine-deprived human neuroblastoma cell line.
    Biochimica et biophysica acta, 2001, Feb-16, Volume: 1525, Issue:1-2

    Topics: Amino Acids; beta-Alanine; Biological Transport, Active; Cell Division; Cycloheximide; DNA, Neoplasm; Glutamic Acid; Glutamine; Humans; Insulin-Like Growth Factor I; Leucine; Neoplasm Proteins; Neuroblastoma; Protein Synthesis Inhibitors; Tumor Cells, Cultured

2001
Regulation of glutamine transport by the type I insulin-like growth factor receptor in a human neuroblastoma cell line.
    Cancer letters, 2001, Jul-10, Volume: 168, Issue:1

    Topics: Apoptosis; Cell Division; Cell Membrane; Dose-Response Relationship, Drug; Glutamine; Humans; Leucine; Neuroblastoma; Protein Transport; Receptor, IGF Type 1; Thymidine; Time Factors; Tumor Cells, Cultured

2001
Characterization of L-glutamine transport by a human neuroblastoma cell line.
    American journal of physiology. Cell physiology, 2002, Volume: 282, Issue:6

    Topics: Amino Acid Transport System ASC; Amino Acids; Biological Transport; Cell Division; Cell Membrane; Choline; Extracellular Space; Glutamine; Humans; Hydrogen-Ion Concentration; Lithium; Minor Histocompatibility Antigens; Neuroblastoma; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; RNA, Messenger; Sodium; Tumor Cells, Cultured

2002
Amino acid transport in a human neuroblastoma cell line is regulated by the type I insulin-like growth factor receptor.
    Life sciences, 2002, May-31, Volume: 71, Issue:2

    Topics: Amino Acids; Antibodies, Monoclonal; Biological Transport; Cell Division; DNA; Flow Cytometry; Glutamine; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Kinetics; Leucine; Neuroblastoma; Protein Biosynthesis; Proteins; Receptor, IGF Type 1; Tumor Cells, Cultured

2002
Enzyme regulation in neuroblastoma cells in a salts/glucose medium: induction of ornithine decarboxylase by asparagine and glutamine.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:9

    Topics: Asparagine; Bucladesine; Carboxy-Lyases; Cell Line; Culture Media; Dactinomycin; Enzyme Induction; Glutamine; Kinetics; Neuroblastoma; Ornithine Decarboxylase; Prostaglandins E; Xanthines

1977
Non-linear kinetics of glutamyl-tRNA synthesis catalyzed by high molecular weight complexes from rat brain neuronal cells but not from glial cells.
    Brain research, 1986, Volume: 387, Issue:1

    Topics: Acylation; Amino Acyl-tRNA Synthetases; Animals; Aspartic Acid; Brain; Catalysis; Cell Line; Glioma; Glutamates; Glutamic Acid; Glutamine; Kinetics; Macromolecular Substances; Mice; Molecular Weight; Neuroblastoma; Neuroglia; Rats; RNA, Transfer, Amino Acyl; Substrate Specificity; Valine

1986
Purine metabolism in normal and thioguanine-resistant neuroblastoma.
    Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:12

    Topics: Adenine; Animals; Carbon Radioisotopes; Clone Cells; Drug Resistance; Glutamine; Humans; Hypoxanthines; Lesch-Nyhan Syndrome; Mice; Neuroblastoma; Pentosyltransferases; Purine Nucleotides; Purines; Thioguanine

1973