Page last updated: 2024-11-04

sevoflurane and Neuroblastoma

sevoflurane has been researched along with Neuroblastoma in 10 studies

Sevoflurane: A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION.
sevoflurane : An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"To determine whether sevoflurane regulates cisplatin resistance in neuroblastoma cells."8.12Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis. ( Fu, X; Guo, H; Li, H; Sun, Y; Wang, D; Zhang, Z, 2022)
"Human neuroblastoma SH-SY5Y cells stably transfected with either wild type or M146L mutant human presenilin 1 were cultured and exposed to equipotent of propofol or sevoflurane."7.96Sevoflurane But Not Propofol Provided Dual Effects of Cell Survival in Human Neuroblastoma SH-SY5Y Cells. ( Gao, X; Liang, G; Mund, R; Wang, X; Wei, H; Zhang, L, 2020)
" Here, we report the phosphoproteome profile of SH-SY5y human neuroblastoma cells treated with sevoflurane, a clinically used anesthetic."7.83Phosphoproteome Profiling of SH-SY5y Neuroblastoma Cells Treated with Anesthetics: Sevoflurane and Isoflurane Affect the Phosphorylation of Proteins Involved in Cytoskeletal Regulation. ( Ahn, E; Lee, J; Park, S; Park, WK, 2016)
"Sevoflurane treatment significantly decreased the cell viability and induced apoptosis of SH-SY5Y cells."5.724.8% sevoflurane induces activation of autophagy in human neuroblastoma SH-SY5Y cells by the AMPK/mTOR signaling pathway. ( Chen, Y; Cheng, H; Jin, X; Li, Y; Liu, C; Lv, J; Yang, Z; Yao, W, 2022)
"Sevoflurane (SEV) is a typical volatile anaesthetic and has an antitumour activity in various cancer cells."5.62Sevoflurane inhibits neuroblastoma cell proliferation and invasion and induces apoptosis by miR-144-3p/YAP1 axis. ( He, K; Shen, J; Yang, L; Yao, S; Zhang, Y, 2021)
" Neuroblastoma cells were exposed to sevoflurane and then cultured in 1% oxygen."3.96Conflicting Actions of Inhalational Anesthetics, Neurotoxicity and Neuroprotection, Mediated by the Unfolded Protein Response. ( Aoe, T; Jin, H; Kokubun, H; Komita, M, 2020)
"Sevoflurane treatment significantly decreased the cell viability and induced apoptosis of SH-SY5Y cells."1.724.8% sevoflurane induces activation of autophagy in human neuroblastoma SH-SY5Y cells by the AMPK/mTOR signaling pathway. ( Chen, Y; Cheng, H; Jin, X; Li, Y; Liu, C; Lv, J; Yang, Z; Yao, W, 2022)
" SDM's toxic effects were tested on neuronal-like SH-SY5Y cells, causing an exponential decrease in viability, while human dermal fibroblasts were completely resistant to the toxic effects."1.37Carnosine protects against the neurotoxic effects of a serotonin-derived melanoid. ( Brownrigg, TD; Fibuch, EE; Seidler, NW; Theisen, CS, 2011)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (40.00)24.3611
2020's6 (60.00)2.80

Authors

AuthorsStudies
Lv, J1
Cheng, H1
Yao, W1
Liu, C1
Chen, Y1
Jin, X1
Yang, Z2
Li, Y1
Li, H3
Fu, X3
Guo, H3
Sun, Y3
Wang, D3
Zhang, Z3
Wang, Y1
Kokubun, H1
Jin, H1
Komita, M1
Aoe, T1
Gao, X1
Wang, X1
Zhang, L1
Liang, G1
Mund, R1
Wei, H1
Yang, L1
He, K1
Yao, S1
Zhang, Y1
Shen, J1
Singh, PM1
Rajeshwari, S1
Borle, A1
Rangasamy, V1
Lee, J1
Ahn, E1
Park, WK1
Park, S1
Lin, D1
Feng, C1
Cao, M1
Zuo, Z1
Brownrigg, TD1
Theisen, CS1
Fibuch, EE1
Seidler, NW1

Other Studies

10 other studies available for sevoflurane and Neuroblastoma

ArticleYear
4.8% sevoflurane induces activation of autophagy in human neuroblastoma SH-SY5Y cells by the AMPK/mTOR signaling pathway.
    Neurotoxicology, 2022, Volume: 90

    Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Cell Line, Tumor; Humans; Neuroblastoma; Sevofl

2022
Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis.
    Saudi medical journal, 2022, Volume: 43, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Mice; MicroRNAs; Neuroblastoma; Pr

2022
Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis.
    Saudi medical journal, 2022, Volume: 43, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Mice; MicroRNAs; Neuroblastoma; Pr

2022
Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis.
    Saudi medical journal, 2022, Volume: 43, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Mice; MicroRNAs; Neuroblastoma; Pr

2022
Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis.
    Saudi medical journal, 2022, Volume: 43, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Mice; MicroRNAs; Neuroblastoma; Pr

2022
Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis.
    Saudi medical journal, 2022, Volume: 43, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Mice; MicroRNAs; Neuroblastoma; Pr

2022
Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis.
    Saudi medical journal, 2022, Volume: 43, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Mice; MicroRNAs; Neuroblastoma; Pr

2022
Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis.
    Saudi medical journal, 2022, Volume: 43, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Mice; MicroRNAs; Neuroblastoma; Pr

2022
Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis.
    Saudi medical journal, 2022, Volume: 43, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Mice; MicroRNAs; Neuroblastoma; Pr

2022
Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis.
    Saudi medical journal, 2022, Volume: 43, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Mice; MicroRNAs; Neuroblastoma; Pr

2022
METTL3 relieved the injury of SH-SY5Y cells treated with lipopolysaccharide and exposed to sevoflurane through regulating the m6A levels of Sox2.
    Brain and behavior, 2023, Volume: 13, Issue:5

    Topics: Aged; Humans; Lipopolysaccharides; Methyltransferases; Neuroblastoma; RNA; RNA, Messenger; Sevoflura

2023
Conflicting Actions of Inhalational Anesthetics, Neurotoxicity and Neuroprotection, Mediated by the Unfolded Protein Response.
    International journal of molecular sciences, 2020, Jan-10, Volume: 21, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Brain; Endoplasmic Reticulum Stress; Female; Male; Mice; Mice, Inb

2020
Sevoflurane But Not Propofol Provided Dual Effects of Cell Survival in Human Neuroblastoma SH-SY5Y Cells.
    Current Alzheimer research, 2020, Volume: 17, Issue:14

    Topics: Calcium; Cell Survival; Cells, Cultured; Humans; Mitochondria; Neuroblastoma; Presenilin-1; Propofol

2020
Sevoflurane inhibits neuroblastoma cell proliferation and invasion and induces apoptosis by miR-144-3p/YAP1 axis.
    Basic & clinical pharmacology & toxicology, 2021, Volume: 129, Issue:4

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Human

2021
Sevoflurane-Based General Anesthesia Induction via Nasopharyngeal Endotracheal Tube Prior to Definitive Airway Control in Pediatric Oral Tumors.
    Anesthesia progress, 2015,Fall, Volume: 62, Issue:3

    Topics: Airway Management; Anesthesia, Endotracheal; Anesthesia, Inhalation; Anesthetics, Inhalation; Child,

2015
Phosphoproteome Profiling of SH-SY5y Neuroblastoma Cells Treated with Anesthetics: Sevoflurane and Isoflurane Affect the Phosphorylation of Proteins Involved in Cytoskeletal Regulation.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Anesthetics, Inhalation; Cell Line, Tumor; Cytoskeleton; Electrophoresis, Gel, Two-Dimensional; Huma

2016
Volatile anesthetics may not induce significant toxicity to human neuron-like cells.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:5

    Topics: Anesthetics, Inhalation; Caspase 3; Cell Differentiation; Cell Line, Tumor; Desflurane; Humans; Isof

2011
Carnosine protects against the neurotoxic effects of a serotonin-derived melanoid.
    Neurochemical research, 2011, Volume: 36, Issue:3

    Topics: Acrolein; Anesthetics, Inhalation; Carnosine; Cell Line; Cell Proliferation; Cell Shape; Cell Surviv

2011