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cilostazol and Neuroblastoma

cilostazol has been researched along with Neuroblastoma in 4 studies

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" We used a human neuroblastoma cell line, SH-SY5Y, to investigate the effect of cilostazol, a specific cAMP phosphodiesterase inhibitor, on NO production and Na+, K+-ATPase activity."7.70Cilostazol, a cyclic AMP phosphodiesterase inhibitor, stimulates nitric oxide production and sodium potassium adenosine triphosphatase activity in SH-SY5Y human neuroblastoma cells. ( Inada, H; Onaya, T; Shindo, H; Tawata, M, 1999)
" We used a human neuroblastoma cell line, SH-SY5Y, to investigate the effect of cilostazol, a specific cAMP phosphodiesterase inhibitor, on NO production and Na+, K+-ATPase activity."3.70Cilostazol, a cyclic AMP phosphodiesterase inhibitor, stimulates nitric oxide production and sodium potassium adenosine triphosphatase activity in SH-SY5Y human neuroblastoma cells. ( Inada, H; Onaya, T; Shindo, H; Tawata, M, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, HR2
Shin, HK2
Park, SY2
Kim, HY2
Lee, WS2
Rhim, BY1
Hong, KW2
Kim, CD2
Suzuki, S1
Masui, Y1
Ohnuki, M1
Miyakoda, G1
Mori, T1
Nakajima, K1
Sato, M1
Inada, H1
Shindo, H1
Tawata, M1
Onaya, T1

Other Studies

4 other studies available for cilostazol and Neuroblastoma

ArticleYear
Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β.
    Journal of neuroscience research, 2014, Volume: 92, Issue:11

    Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Benzamides; Cell Line, Tumor;

2014
Cilostazol Modulates Autophagic Degradation of β-Amyloid Peptide via SIRT1-Coupled LKB1/AMPKα Signaling in Neuronal Cells.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: AMP-Activated Protein Kinases; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autop

2016
Induction of metallothionein synthesis by cilostazol in mice and in human cultured neuronal cell lines.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:4

    Topics: Animals; Brain Chemistry; Cell Line, Tumor; Cilostazol; Dose-Response Relationship, Drug; Humans; In

2007
Cilostazol, a cyclic AMP phosphodiesterase inhibitor, stimulates nitric oxide production and sodium potassium adenosine triphosphatase activity in SH-SY5Y human neuroblastoma cells.
    Life sciences, 1999, Volume: 65, Issue:13

    Topics: Cilostazol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Humans; Inositol; Isoqu

1999