Page last updated: 2024-12-11

quercetin-3'-o-beta-d-glucopyranoside

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

quercetin 3'-O-glucoside: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5748594
SCHEMBL ID1962101
MeSH IDM0507041

Synonyms (8)

Synonym
flavone, 3,3',4',5,7-pentahydroxy-, 3'-beta-d-glucopyranoside
quercetin 3'-o-beta-d-glucopyranoside
quercetin 3'-o-glucoside
4h-1-benzopyran-4-one, 2-(3-(beta-d-glucopyranosyloxy)-4-hydroxyphenyl)-3,5,7-trihydroxy-
3,5,7-trihydroxy-2-[4-hydroxy-3-[(3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one
SCHEMBL1962101
DTXSID40940916
2-hydroxy-5-(3,5,7-trihydroxy-4-oxo-4h-1-benzopyran-2-yl)phenyl hexopyranoside

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Treatment of TAA intoxicated rats (G4) with MOLE ameliorated the toxic effects of TAA on hepatic tissue structure and function."( Protective effect of Moringa oleifera leaves ethanolic extract against thioacetamide-induced hepatotoxicity in rats via modulation of cellular antioxidant, apoptotic and inflammatory markers.
El Sabagh, HS; El-Gansh, HAI; Eldaim, MAA; Mohamed, MAE; Morsi, AH; Mousa, AA, 2019
)
0.51

Bioavailability

ExcerptReferenceRelevance
" The absorption rate of flavonoid glycoside was lower than that of aglycone; the flavonoids from Abelmoschus manihot flowers could be absorbed in all of the intestinal segments."( [Absorption of flavonoids from Abelmoschus manihot extract by in situ intestinal perfusion].
Duan, JA; Guo, JM; Qian, DW; Shu, Y; Xue, CF, 2011
)
0.37
"Despite their strong role in human health, poor bioavailability of flavonoids limits their biological effects in vivo."( Antiproliferative activity of long chain acylated esters of quercetin-3-O-glucoside in hepatocellular carcinoma HepG2 cells.
Rupasinghe, HV; Sudan, S, 2015
)
0.42
" Certain flavonoids, in particular quercetin, have been shown to ameliorate endothelial dysfunction and reduce blood pressure (BP), possibly by increasing the bioavailability of the potent vasodilator nitric oxide (NO)."( Acute effects of quercetin-3-O-glucoside on endothelial function and blood pressure: a randomized dose-response study.
Bondonno, CP; Bondonno, NP; Croft, KD; Hodgson, JM; Mas, E; Rich, L; Shinde, S; Ward, NC, 2016
)
0.43
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (49)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (4.08)29.6817
2010's40 (81.63)24.3611
2020's7 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.80

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.80 (24.57)
Research Supply Index3.97 (2.92)
Research Growth Index5.78 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.80)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (1.96%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other50 (98.04%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]