| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
mannitol
[no description available] | 2 | 1 | 0 | mannitol | allergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent |
ciguatoxins
Ciguatoxins: Polycyclic ethers produced by Gambierdiscus (DINOFLAGELLATES) from gambiertoxins, which are ingested by fish which in turn may be ingested by humans who are susceptible to the CIGUATERA POISONING.. ciguatoxin CTX1B : A ciguatoxin comprising a sequence of twelve trans-fused six-, seven-, eight- and nine-membered rings and a spiro-fused five-membered ring. A commonly encountered fish toxin.. ciguatoxin : Ciguatoxins are cyclic polyether toxins, derived from marine dinoflagellates, which are responsible for the symptoms of ciguatera poisoning. Ingestion of tropical and subtropical fin fish contaminated by ciguatoxins results in an illness characterised by neurological, cardiovascular and gastrointestinal disorders. | 3.42 | 7 | 0 | ciguatoxin | metabolite |
brevetoxin t17
brevetoxin T17: from Florida red tide organism Ptychodiscus brevis; neuromuscular blocking action; structure given in first source | 2 | 1 | 0 | | |
gambierol
gambierol: structure in first source | 2.03 | 1 | 0 | | |
brevetoxin a
Brevetoxin A: structure given in first source; from dinoflagellate, Gymnodinium breve. brevetoxin A : A ciguatoxin comprising a linear sequence of ten trans-fused five-, six-, eight- and nine-membered rings. | 2 | 1 | 0 | ciguatoxin | |
veratridine
Veratridine: A benzoate-cevane found in VERATRUM and Schoenocaulon. It activates SODIUM CHANNELS to stay open longer than normal. | 2.03 | 1 | 0 | | |
a 803467
A 803467: an Nav1.8 sodium channel blocker; structure in first source | 2.11 | 1 | 0 | | |
a 967079
A 967079: a TRPA1 channel antagonist; structure in first source | 2.11 | 1 | 0 | | |
brevetoxin
brevetoxin: from Ptychodiscus brevis | 2.31 | 1 | 0 | | |
saxitoxin
Saxitoxin: A compound that contains a reduced purine ring system but is not biosynthetically related to the purine alkaloids. It is a poison found in certain edible mollusks at certain times; elaborated by GONYAULAX and consumed by mollusks, fishes, etc. without ill effects. It is neurotoxic and causes RESPIRATORY PARALYSIS and other effects in MAMMALS, known as paralytic SHELLFISH poisoning.. saxitoxin : An alkaloid isolated from the marine dinoflagellates and cyanobacteria that causes paralytic shellfish poisoning. | 2.03 | 1 | 0 | alkaloid;
carbamate ester;
guanidines;
ketone hydrate;
paralytic shellfish toxin;
pyrrolopurine | cyanotoxin;
marine metabolite;
neurotoxin;
sodium channel blocker;
toxin |