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sodium iodide and Neuroblastoma

sodium iodide has been researched along with Neuroblastoma in 2 studies

Sodium Iodide: A compound forming white, odorless deliquescent crystals and used as iodine supplement, expectorant or in its radioactive (I-131) form as an diagnostic aid, particularly for thyroid function tests.
sodium iodide : A metal iodide salt with a Na(+) counterion.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" The Auger electron-emitting conjugates ([123I]MIBG and [125I]MIBG) and the alpha-emitting conjugate ([211At]MABG) were highly toxic to monolayers and small spheroids, whereas the beta-emitting conjugate [131I]MIBG was relatively ineffective."1.30Toxicity to neuroblastoma cells and spheroids of benzylguanidine conjugated to radionuclides with short-range emissions. ( Cunningham, SH; Mairs, RJ; Vaidyanathan, G; Welsh, PC; Wheldon, TE; Zalutsky, MR, 1998)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cunningham, SH2
Mairs, RJ2
Wheldon, TE1
Welsh, PC1
Vaidyanathan, G1
Zalutsky, MR1
Carlin, S1
Boyd, M1
McCluskey, AG1

Other Studies

2 other studies available for sodium iodide and Neuroblastoma

ArticleYear
Toxicity to neuroblastoma cells and spheroids of benzylguanidine conjugated to radionuclides with short-range emissions.
    British journal of cancer, 1998, Volume: 77, Issue:12

    Topics: 3-Iodobenzylguanidine; Antineoplastic Agents; Astatine; Combined Modality Therapy; Guanidines; Human

1998
Experimental targeted radioiodide therapy following transfection of the sodium iodide symporter gene: effect on clonogenicity in both two-and three-dimensional models.
    Cancer gene therapy, 2000, Volume: 7, Issue:12

    Topics: Adenocarcinoma; Carrier Proteins; Disease Models, Animal; Female; Gene Expression; Glioma; Humans; I

2000