Page last updated: 2024-10-22

amlodipine and Neuroblastoma

amlodipine has been researched along with Neuroblastoma in 2 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"In this study, it was aimed to determine the effects of Amlodipine, a calcium channel blocker and vincristine (VCR) an antineoplastic, on human neuroblastomas using different doses."3.91Vincristine combination with Ca ( Güllüce, M; Hacimuftuoglu, A; Sezen, S; Taghizadehghalehjoughi, A, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Taghizadehghalehjoughi, A1
Sezen, S1
Hacimuftuoglu, A1
Güllüce, M1
An Haack, K1
Narayan, SB1
Li, H1
Warnock, A1
Tan, L1
Bennett, MJ1

Other Studies

2 other studies available for amlodipine and Neuroblastoma

ArticleYear
Vincristine combination with Ca
    Molecular biology reports, 2019, Volume: 46, Issue:2

    Topics: Amlodipine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Calcium Channel B

2019
Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers.
    Biochimica et biophysica acta, 2011, Volume: 1810, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2011