Page last updated: 2024-10-30

methenamine and Neuroblastoma

methenamine has been researched along with Neuroblastoma in 1 studies

Methenamine: An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)
hexamethylenetetramine : A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Swift, LP1
Cutts, SM1
Rephaeli, A1
Nudelman, A1
Phillips, DR1

Other Studies

1 other study available for methenamine and Neuroblastoma

ArticleYear
Activation of adriamycin by the pH-dependent formaldehyde-releasing prodrug hexamethylenetetramine.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:2

    Topics: Antineoplastic Agents; Biotransformation; DNA Adducts; DNA, Neoplasm; Doxorubicin; Formaldehyde; Hum

2003