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iodoacetic acid and Neuroblastoma

iodoacetic acid has been researched along with Neuroblastoma in 4 studies

Iodoacetic Acid: A derivative of ACETIC ACID that contains one IODINE atom attached to its methyl group.
iodoacetic acid : A haloacetic acid that is acetic acid in which one of the hydrogens of the methyl group is replaced by an iodine atom.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
" Mouse neuroblastoma cell cultures (Neuro-2a) were exposed to different concentrations of the toxic compounds for 24, 48 and 72 h to study basal toxicity effects (cell proliferation by quantification of total protein content (PR) and relative neutral red uptake (RNRU) by lysosomes)."7.69Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro. ( Andrés, MI; Repetto, G; Repetto, M; Sanz, P, 1996)
" Mouse neuroblastoma cell cultures (Neuro-2a) were exposed to different concentrations of the toxic compounds for 24, 48 and 72 h to study basal toxicity effects (cell proliferation by quantification of total protein content (PR) and relative neutral red uptake (RNRU) by lysosomes)."3.69Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro. ( Andrés, MI; Repetto, G; Repetto, M; Sanz, P, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erdmann, F1
Jarczowski, F1
Weiwad, M1
Fischer, G1
Edlich, F1
Andrés, MI1
Repetto, G1
Sanz, P1
Repetto, M1
Mackert, BM1
Staub, F1
Peters, J1
Baethmann, A1
Kempski, O1
Ray, P1
Monroe, FL1
Berman, JD1
Fiedler, J1

Other Studies

4 other studies available for iodoacetic acid and Neuroblastoma

ArticleYear
Hsp90-mediated inhibition of FKBP38 regulates apoptosis in neuroblastoma cells.
    FEBS letters, 2007, Dec-11, Volume: 581, Issue:29

    Topics: Apoptosis; Binding Sites; Calcium; Calmodulin; Cell Death; Cell Line, Tumor; HSP90 Heat-Shock Protei

2007
Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro.
    Toxicology, 1996, Jun-17, Volume: 110, Issue:1-3

    Topics: 2,4-Dinitrophenol; Acetylcholinesterase; Animals; beta-Galactosidase; Cell Division; Dinitrophenols;

1996
Anoxia in vitro does not induce neuronal swelling or death.
    Journal of the neurological sciences, 1996, Volume: 139, Issue:1

    Topics: Aerobiosis; Analysis of Variance; Animals; Cell Hypoxia; Cell Line; Hypertonic Solutions; Iodoacetat

1996
Cyanide sensitive and insensitive bioenergetics in a clonal neuroblastoma x glioma hybrid cell line.
    Neurochemical research, 1991, Volume: 16, Issue:10

    Topics: Adenosine Triphosphate; Animals; Clone Cells; Cobalt; Deoxyglucose; Glioma; Hybrid Cells; Iodoacetat

1991