lomustine has been researched along with Neuroblastoma in 4 studies
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients older than 1 year with either metastatic or localised stage 2-3 MYCN-amplified neuroblastoma received 2 courses of high-dose topotecan (HD-TPT) 6mg/m(2) and high-dose cyclophosphamide (HD-CPM) 140 mg/kg, followed by 2 courses of ifosfamide, carboplatin and etoposide (ICE) every 28 days." | 7.77 | Short topotecan-based induction regimen in newly diagnosed high-risk neuroblastoma. ( Castellano, A; De Ioris, MA; De Pasquale, MD; De Vito, R; Donfrancesco, A; Garganese, MC; Ilari, I; Inserra, A; Jenkner, A; Locatelli, F; Natali, G; Ravà, L, 2011) |
| "Patients older than 1 year with either metastatic or localised stage 2-3 MYCN-amplified neuroblastoma received 2 courses of high-dose topotecan (HD-TPT) 6mg/m(2) and high-dose cyclophosphamide (HD-CPM) 140 mg/kg, followed by 2 courses of ifosfamide, carboplatin and etoposide (ICE) every 28 days." | 3.77 | Short topotecan-based induction regimen in newly diagnosed high-risk neuroblastoma. ( Castellano, A; De Ioris, MA; De Pasquale, MD; De Vito, R; Donfrancesco, A; Garganese, MC; Ilari, I; Inserra, A; Jenkner, A; Locatelli, F; Natali, G; Ravà, L, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Ioris, MA | 1 |
| Castellano, A | 1 |
| Ilari, I | 1 |
| Garganese, MC | 1 |
| Natali, G | 1 |
| Inserra, A | 1 |
| De Vito, R | 1 |
| Ravà, L | 1 |
| De Pasquale, MD | 1 |
| Locatelli, F | 1 |
| Donfrancesco, A | 1 |
| Jenkner, A | 1 |
| Aguila, B | 1 |
| Coulbault, L | 1 |
| Boulouard, M | 1 |
| Léveillé, F | 1 |
| Davis, A | 1 |
| Tóth, G | 1 |
| Borsodi, A | 1 |
| Balboni, G | 1 |
| Salvadori, S | 1 |
| Jauzac, P | 1 |
| Allouche, S | 1 |
| Castel, V | 1 |
| Badal, MD | 1 |
| Bezanilla, JL | 1 |
| Llombart, A | 1 |
| Ruiz-Jiménez, JI | 1 |
| Sánchez de Toledo, J | 1 |
| Melero, C | 1 |
| Mulet, J | 1 |
| Schuler, D | 1 |
| Koós, R | 1 |
| Krauze, I | 1 |
| Péter, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| European Low and Intermediate Risk Neuroblastoma Protocol[NCT01728155] | Phase 3 | 685 participants (Actual) | Interventional | 2011-01-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for lomustine and Neuroblastoma
| Article | Year |
|---|---|
Treatment of stage III neuroblastoma with emphasis on intensive induction chemotherapy: a report from the Neuroblastoma Group of the Spanish Society of Pediatric Oncology.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Infant; Lomustine; Male; | 1995 |
3 other studies available for lomustine and Neuroblastoma
| Article | Year |
|---|---|
Short topotecan-based induction regimen in newly diagnosed high-risk neuroblastoma.
Topics: Abdominal Neoplasms; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; | 2011 |
In vitro and in vivo pharmacological profile of UFP-512, a novel selective delta-opioid receptor agonist; correlations between desensitization and tolerance.
Topics: Animals; Antidepressive Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bind | 2007 |
Paraneoplastic syndrome in childhood.
Topics: Brain Diseases; Carmustine; Child, Preschool; Humans; Lomustine; Male; Mediastinal Neoplasms; Methot | 1977 |