1,10-phenanthroline has been researched along with Neuroblastoma in 3 studies
1,10-phenanthroline: RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Murine neuroblastoma clone N1E-115, which possesses receptors for neurotensin mediating the formation of intracellular cyclic GMP and the stimulation of inositol phospholipid hydrolysis, exhibited only partial desensitization to neurotensin." | 7.67 | Rapid degradation of neurotensin by intact murine neuroblastoma cells (clone N1E-115). ( Gilbert, JA; Hanson, PD; McCormick, DJ; Richelson, E, 1987) |
| "Murine neuroblastoma clone N1E-115, which possesses receptors for neurotensin mediating the formation of intracellular cyclic GMP and the stimulation of inositol phospholipid hydrolysis, exhibited only partial desensitization to neurotensin." | 3.67 | Rapid degradation of neurotensin by intact murine neuroblastoma cells (clone N1E-115). ( Gilbert, JA; Hanson, PD; McCormick, DJ; Richelson, E, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bandarra, D | 1 |
| Lopes, M | 1 |
| Lopes, T | 1 |
| Almeida, J | 1 |
| Saraiva, MS | 1 |
| Vasconcellos-Dias, M | 1 |
| Nunes, CD | 1 |
| Félix, V | 1 |
| Brandão, P | 1 |
| Vaz, PD | 1 |
| Meireles, M | 1 |
| Calhorda, MJ | 1 |
| Matsumoto, T | 1 |
| Gargosky, SE | 1 |
| Kelley, K | 1 |
| Rosenfeld, RG | 1 |
| Gilbert, JA | 1 |
| Hanson, PD | 1 |
| McCormick, DJ | 1 |
| Richelson, E | 1 |
3 other studies available for 1,10-phenanthroline and Neuroblastoma
| Article | Year |
|---|---|
Mo(II) complexes: a new family of cytotoxic agents?
Topics: 1-Octanol; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Dos | 2010 |
Characterization of an insulin-like growth factor binding protein-5 protease produced by rat articular chondrocytes and a neuroblastoma cell line.
Topics: Animals; Aprotinin; Benzamides; Calcium; Cartilage, Articular; Cations, Divalent; Cell Line; Cells, | 1996 |
Rapid degradation of neurotensin by intact murine neuroblastoma cells (clone N1E-115).
Topics: Animals; Chromatography, High Pressure Liquid; Dipeptides; Kinetics; Mice; Neuroblastoma; Neurotensi | 1987 |