toluene has been researched along with Neuroblastoma in 6 studies
methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Curcumin treatment activated p53 through hyperphosphorylation at serine 15 before Bex genes induction indicating Bex genes are novel downstream targets of p53." | 5.46 | Induction of Bex genes by curcumin is associated with apoptosis and activation of p53 in N2a neuroblastoma cells. ( Giri, RK; Sidhar, H, 2017) |
| "Effects of the neurotoxic organic solvent toluene on human neuronal nicotinic acetylcholine (nACh) and gamma-aminobutyric acid type A (GABA(A)) neurotransmitter receptors were investigated in whole-cell voltage-clamped IMR-32 neuroblastoma cells." | 3.72 | Selective inhibition of gamma-aminobutyric acid type A receptors in human IMR-32 cells by low concentrations of toluene. ( Meulenberg, CJ; Vijverberg, HP, 2003) |
| "Curcumin treatment activated p53 through hyperphosphorylation at serine 15 before Bex genes induction indicating Bex genes are novel downstream targets of p53." | 1.46 | Induction of Bex genes by curcumin is associated with apoptosis and activation of p53 in N2a neuroblastoma cells. ( Giri, RK; Sidhar, H, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Da Pozzo, E | 1 |
| La Pietra, V | 1 |
| Cosimelli, B | 1 |
| Da Settimo, F | 1 |
| Giacomelli, C | 1 |
| Marinelli, L | 1 |
| Martini, C | 1 |
| Novellino, E | 1 |
| Taliani, S | 1 |
| Greco, G | 1 |
| Sidhar, H | 1 |
| Giri, RK | 1 |
| Tamagno, E | 1 |
| Parola, M | 1 |
| Guglielmotto, M | 1 |
| Santoro, G | 1 |
| Bardini, P | 1 |
| Marra, L | 1 |
| Tabaton, M | 1 |
| Danni, O | 1 |
| Meulenberg, CJ | 1 |
| Vijverberg, HP | 1 |
| Nakaso, K | 1 |
| Yoshimoto, Y | 1 |
| Yano, H | 1 |
| Takeshima, T | 1 |
| Nakashima, K | 1 |
| McDermott, C | 1 |
| Allshire, A | 1 |
| van Pelt, FN | 1 |
| Heffron, JJ | 1 |
6 other studies available for toluene and Neuroblastoma
| Article | Year |
|---|---|
p53 functional inhibitors behaving like pifithrin-β counteract the Alzheimer peptide non-β-amyloid component effects in human SH-SY5Y cells.
Topics: Amyloid beta-Peptides; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Dose-Response Relationsh | 2014 |
Induction of Bex genes by curcumin is associated with apoptosis and activation of p53 in N2a neuroblastoma cells.
Topics: Androstadienes; Animals; Anthracenes; Apoptosis; Benzothiazoles; Cell Line, Tumor; Curcumin; Enzyme | 2017 |
Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis.
Topics: Acetylcysteine; alpha-Tocopherol; Amyloid beta-Peptides; Apoptosis; bcl-2-Associated X Protein; Benz | 2003 |
Selective inhibition of gamma-aminobutyric acid type A receptors in human IMR-32 cells by low concentrations of toluene.
Topics: Acetylcholine; GABA-A Receptor Antagonists; Humans; Ion Channels; Neuroblastoma; Neurons; Occupation | 2003 |
p53-mediated mitochondrial dysfunction by proteasome inhibition in dopaminergic SH-SY5Y cells.
Topics: bcl-2-Associated X Protein; Benzimidazoles; Benzothiazoles; Blotting, Western; Carbocyanines; Cell D | 2004 |
Validation of a method for acute and subchronic exposure of cells in vitro to volatile organic solvents.
Topics: Acute Disease; Algorithms; Brain Neoplasms; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physica | 2007 |