entinostat has been researched along with Neuroblastoma in 5 studies
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using human neuroblastoma cell lines, SK-N-MC, SH-SY5Y, and SK-N-SH, we show that non-toxic dose (2 mM) of VPA enhanced staurosporine (STS)-induced cell death as assessed by MTT assay, PARP cleavage, hypodiploidy, and caspase 3 activity." | 7.79 | Sodium valproate potentiates staurosporine-induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition. ( Das, G; Jagtap, JC; Mruthyunjaya, S; Pujari, R; Shah, RD; Shastry, P; Shelke, GV, 2013) |
| " In this study, treatment with histone deacetylase (HDAC) inhibitors, trichostatin A (TSA), valproic acid, tubacin and the class I HDAC inhibitor, MS-275, were found to increase cPLA2α messenger RNA (mRNA) expression in SH-SY5Y human neuroblastoma cells." | 3.83 | Epigenetic Regulation of Cytosolic Phospholipase A2 in SH-SY5Y Human Neuroblastoma Cells. ( Ng, YK; Ong, WY; Tan, CS, 2016) |
| " Using human neuroblastoma cell lines, SK-N-MC, SH-SY5Y, and SK-N-SH, we show that non-toxic dose (2 mM) of VPA enhanced staurosporine (STS)-induced cell death as assessed by MTT assay, PARP cleavage, hypodiploidy, and caspase 3 activity." | 3.79 | Sodium valproate potentiates staurosporine-induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition. ( Das, G; Jagtap, JC; Mruthyunjaya, S; Pujari, R; Shah, RD; Shastry, P; Shelke, GV, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cornel, AM | 2 |
| Dunnebach, E | 2 |
| Hofman, DA | 2 |
| Das, S | 2 |
| Sengupta, S | 2 |
| van den Ham, F | 2 |
| Wienke, J | 2 |
| Strijker, JGM | 2 |
| van den Beemt, DAMH | 2 |
| Essing, AHW | 2 |
| Koopmans, B | 2 |
| Engels, SAG | 2 |
| Lo Presti, V | 2 |
| Szanto, CS | 2 |
| George, RE | 2 |
| Molenaar, JJ | 2 |
| van Heesch, S | 2 |
| Dierselhuis, MP | 2 |
| Nierkens, S | 2 |
| Choi, J | 1 |
| Hwang, J | 1 |
| Ramalingam, M | 1 |
| Jeong, HS | 1 |
| Jang, S | 1 |
| Tan, CS | 1 |
| Ng, YK | 1 |
| Ong, WY | 1 |
| Bayat Mokhtari, R | 1 |
| Baluch, N | 1 |
| Ka Hon Tsui, M | 1 |
| Kumar, S | 1 |
| S Homayouni, T | 1 |
| Aitken, K | 1 |
| Das, B | 1 |
| Baruchel, S | 1 |
| Yeger, H | 1 |
| Shah, RD | 1 |
| Jagtap, JC | 1 |
| Mruthyunjaya, S | 1 |
| Shelke, GV | 1 |
| Pujari, R | 1 |
| Das, G | 1 |
| Shastry, P | 1 |
5 other studies available for entinostat and Neuroblastoma
| Article | Year |
|---|---|
Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch.
Topics: Cell Lineage; Epigenesis, Genetic; Histocompatibility Antigens Class I; Histone Deacetylase Inhibito | 2022 |
Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch.
Topics: Cell Lineage; Epigenesis, Genetic; Histocompatibility Antigens Class I; Histone Deacetylase Inhibito | 2022 |
Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch.
Topics: Cell Lineage; Epigenesis, Genetic; Histocompatibility Antigens Class I; Histone Deacetylase Inhibito | 2022 |
Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch.
Topics: Cell Lineage; Epigenesis, Genetic; Histocompatibility Antigens Class I; Histone Deacetylase Inhibito | 2022 |
Effects of HDAC inhibitors on neuroblastoma SH-SY5Y cell differentiation into mature neurons via the Wnt signaling pathway.
Topics: Cell Differentiation; Cell Line, Tumor; Histone Deacetylase Inhibitors; Humans; Neuroblastoma; Neuro | 2023 |
Epigenetic Regulation of Cytosolic Phospholipase A2 in SH-SY5Y Human Neuroblastoma Cells.
Topics: Anacardic Acids; Anilides; Benzamides; Cell Line, Tumor; Chromatin Immunoprecipitation; Deoxyadenosi | 2016 |
Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma.
Topics: Acetazolamide; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Carbonic Anhydrase Inhibitors; | 2017 |
Sodium valproate potentiates staurosporine-induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Caspase 3; Cell Line, Tumor; Cell Survival; Dose-Respo | 2013 |