perifosine has been researched along with Neuroblastoma in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chin, M; Kato, K; Kawamoto, H; Kosaka, Y; Matsumoto, K; Mugishima, H; Shichino, H | 1 |
| Becher, OJ; Cheung, NV; De Braganca, KC; Dunkel, IJ; Gilheeney, SW; Haque, S; Huse, JT; Khakoo, Y; Kolesar, JM; Kramer, K; Kushner, BH; Lyden, DC; Millard, NE; Modak, S; Spasojevic, I; Trippett, TM | 1 |
| Cheng, H; Li, L; Liu, W; Xin, Q; Ya, B; Yu, T | 1 |
| Boratyn, E; Durbas, M; Horwacik, I; Kamycka, E; Rokita, H | 1 |
| Basu, EM; Becher, OJ; Cheung, NV; Dunkel, IJ; Kramer, K; Kushner, BH; Modak, S; Roberts, SS | 1 |
| Dong, Y; Gu, X; Hua, Z; Li, Z; Liu, Z; Thiele, CJ; Tian, W; Zhan, Y; Zhang, X | 1 |
| Brodeur, GM | 1 |
| Li, Z; Liewehr, DJ; Steinberg, SM; Tan, F; Thiele, CJ | 1 |
| Li, Z; Nakamura, K; Oh, DY; Thiele, CJ | 1 |
3 trial(s) available for perifosine and Neuroblastoma
| Article | Year |
|---|---|
Phase I study of perifosine monotherapy in patients with recurrent or refractory neuroblastoma.
Topics: Adolescent; Adult; Child; Child, Preschool; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Male; Maximum Tolerated Dose; Neoplasm Recurrence, Local; Neoplasm Staging; Neuroblastoma; Phosphorylcholine; Prognosis; Proto-Oncogene Proteins c-akt; Salvage Therapy; Signal Transduction; Survival Rate; Young Adult | 2017 |
A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors.
Topics: Adolescent; Antineoplastic Agents; Central Nervous System Neoplasms; Child; Child, Preschool; Drug Administration Schedule; Ependymoma; Female; Glioma; Humans; Hyperuricemia; Male; Medulloblastoma; Neoplasm Recurrence, Local; Neuroblastoma; Neutropenia; Phosphorylcholine; Sarcoma, Ewing; Treatment Outcome; Wilms Tumor | 2017 |
A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Disease-Free Survival; Female; Humans; Male; Neoplasm Recurrence, Local; Neuroblastoma; Phosphatidylinositol 3-Kinases; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Signal Transduction; Young Adult | 2017 |
6 other study(ies) available for perifosine and Neuroblastoma
| Article | Year |
|---|---|
Silencing of NADPH Oxidase 4 Attenuates Hypoxia Resistance in Neuroblastoma Cells SH-SY5Y by Inhibiting PI3K/Akt-Dependent Glycolysis.
Topics: Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Silencing; Glycolysis; Humans; Hypoxia; Insulin-Like Growth Factor I; Membrane Potential, Mitochondrial; NADPH Oxidase 4; Neuroblastoma; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylcholine; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction | 2019 |
GD2 ganglioside specific antibody treatment downregulates PI3K/Akt/mTOR signaling network in human neuroblastoma cell lines.
Topics: Antibodies, Monoclonal; Apoptosis; Cell Line, Tumor; Drug Synergism; Gangliosides; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Neuroblastoma; Phosphatidylinositol 3-Kinases; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Quinolines; Quinoxalines; Signal Transduction; Sulfonamides; TOR Serine-Threonine Kinases | 2015 |
Proteome and Acetylome Analysis Identifies Novel Pathways and Targets Regulated by Perifosine in Neuroblastoma.
Topics: Acetylation; Amino Acids; Antineoplastic Agents; Cell Line, Tumor; Chromatography, Liquid; Humans; Lysine; Metabolic Networks and Pathways; Neuroblastoma; Phosphorylcholine; Proteome; Tandem Mass Spectrometry | 2017 |
Getting into the AKT.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Clinical Trials as Topic; Disease Models, Animal; Growth Inhibitors; Humans; Mice; Neuroblastoma; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Receptor Protein-Tyrosine Kinases; Transplantation, Heterologous | 2010 |
In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Clinical Trials as Topic; Disease Models, Animal; Growth Inhibitors; Humans; In Vitro Techniques; Kaplan-Meier Estimate; Luciferases; Luminescent Agents; Mice; Mutation; Neuroblastoma; NIH 3T3 Cells; Phosphorylation; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Transplantation, Heterologous | 2010 |
Perifosine-induced inhibition of Akt attenuates brain-derived neurotrophic factor/TrkB-induced chemoresistance in neuroblastoma in vivo.
Topics: Brain Neoplasms; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Drug Resistance, Neoplasm; Etoposide; Humans; Neuroblastoma; Phosphorylation; Phosphorylcholine; Proto-Oncogene Proteins c-akt; Receptor, trkB; Tetracycline | 2011 |