Page last updated: 2024-11-01

nitrendipine and Neuroblastoma

nitrendipine has been researched along with Neuroblastoma in 11 studies

Nitrendipine: A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
nitrendipine : A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"The effects of nifedipine, niguldipine, nimodipine and nitrendipine on the high K+-induced intracellular Ca2+ ([Ca2+]i) transient in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid NG 108-15 cells were studied by using the fluorescent Ca2+ indicator fura-2."7.69Nimodipine and nitrendipine inhibit N-type calcium channels in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid (NG 108-15) cells. ( Andreas, K; Bräter, M; Li, SN, 1997)
"The effects of nifedipine, niguldipine, nimodipine and nitrendipine on the high K+-induced intracellular Ca2+ ([Ca2+]i) transient in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid NG 108-15 cells were studied by using the fluorescent Ca2+ indicator fura-2."3.69Nimodipine and nitrendipine inhibit N-type calcium channels in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid (NG 108-15) cells. ( Andreas, K; Bräter, M; Li, SN, 1997)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's6 (54.55)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, J1
Sutachan, JJ1
Montoya-Gacharna, J1
Xu, CF1
Xu, F1
Neubert, TA1
Recio-Pinto, E1
Blanck, TJ1
Ween, H1
Thorin-Hagene, K1
Andersen, E1
Grønlien, JH1
Lee, CH1
Gopalakrishnan, M1
Malysz, J1
Freedman, SB1
Miller, RJ1
Ichida, S1
Wada, T1
Nakazaki, S1
Matsuda, N1
Kishino, H1
Akimoto, T1
Lo, TM1
Thayer, SA1
Li, SN1
Bräter, M1
Andreas, K1
Rondé, P1
Nichols, RA1
Hiley, CR1
Cowley, DJ1
Pelton, JT1
Hargreaves, AC1
Peers, C1
Lang, B1
Newsom-Davis, J1
Wray, DW1
Sher, E1
Pandiella, A1
Clementi, F1
Callewaert, G1
Hanbauer, I1
Morad, M1

Other Studies

11 other studies available for nitrendipine and Neuroblastoma

ArticleYear
Isoflurane inhibits cyclic adenosine monophosphate response element-binding protein phosphorylation and calmodulin translocation to the nucleus of SH-SY5Y cells.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2009
Alpha3* and alpha 7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells.
    Neurochemistry international, 2010, Volume: 57, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Benzamides; Brain Neoplasms; Bridged Bicyclo Compounds; Cal

2010
Calcium channel activation: a different type of drug action.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:17

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1984
Specific bindings of [3H](+)PN200-110 and [125I]omega-conotoxin to crude membranes from differentiated NG108-15 cells.
    Neurochemical research, 1993, Volume: 18, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Refilling the inositol 1,4,5-trisphosphate-sensitive Ca2+ store in neuroblastoma x glioma hybrid NG108-15 cells.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1

    Topics: Animals; Bradykinin; Calcium; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Flunar

1993
Nimodipine and nitrendipine inhibit N-type calcium channels in dibutyryl cAMP-differentiated neuroblastoma x glioma hybrid (NG 108-15) cells.
    Neuroscience letters, 1997, Jul-18, Volume: 230, Issue:2

    Topics: Animals; Bucladesine; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Dih

1997
High calcium permeability of serotonin 5-HT3 receptors on presynaptic nerve terminals from rat striatum.
    Journal of neurochemistry, 1998, Volume: 70, Issue:3

    Topics: Animals; Biguanides; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability

1998
BQ-123, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu), is a non-competitive antagonist of the actions of endothelin-1 in SK-N-MC human neuroblastoma cells.
    Biochemical and biophysical research communications, 1992, Apr-15, Volume: 184, Issue:1

    Topics: Calcium; Cell Line; Dose-Response Relationship, Drug; Endothelins; Humans; Kinetics; Neuroblastoma;

1992
Selective action of myasthenic syndrome antibodies on calcium channels in a rodent neuroblastoma x glioma cell line.
    The Journal of physiology, 1990, Volume: 421

    Topics: Action Potentials; Animals; Antibodies, Neoplasm; Calcium Channels; Cell Line; Glioma; Humans; Immun

1990
Omega-conotoxin binding and effects on calcium channel function in human neuroblastoma and rat pheochromocytoma cell lines.
    FEBS letters, 1988, Aug-01, Volume: 235, Issue:1-2

    Topics: Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Dihydropyridi

1988
Modulation of calcium channels in cardiac and neuronal cells by an endogenous peptide.
    Science (New York, N.Y.), 1989, Feb-03, Volume: 243, Issue:4891

    Topics: Angiotensin II; Animals; Brain Chemistry; Calcium Channels; Cell Line; Cell Membrane; Chromatography

1989