propofol has been researched along with Neuroblastoma in 13 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the role and mechanism of action of propofol on OGD/Rinduced inflammation in mouse N2A neuroblastoma cells." | 7.96 | Propofol Pretreatment Prevents Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-induced Inflammation Through Nuclear Transcription Factor κB (NF-κB) Pathway in Neuroblastoma Cells. ( Hu, F; Jiang, J; Sun, H; Yu, G; Zang, H, 2020) |
| "Human neuroblastoma SH-SY5Y cells stably transfected with either wild type or M146L mutant human presenilin 1 were cultured and exposed to equipotent of propofol or sevoflurane." | 7.96 | Sevoflurane But Not Propofol Provided Dual Effects of Cell Survival in Human Neuroblastoma SH-SY5Y Cells. ( Gao, X; Liang, G; Mund, R; Wang, X; Wei, H; Zhang, L, 2020) |
| "We have examined the effects of two intravenous anaesthetic induction agents, propofol and thiopentone, on K+ and carbachol evoked [3H]noradrenaline release from a human neuroblastoma cell line, SH-SY5Y." | 7.69 | Effects of propofol and thiopentone on potassium- and carbachol-evoked [3H]noradrenaline release and increased [Ca2+]i from SH-SY5Y human neuroblastoma cells. ( Atcheson, R; Frost, C; Lambert, DG; Rowbotham, DJ; Smart, D; Smith, G; Willets, JM, 1996) |
| "Propofol (PPF) has been shown in studies to cause cognitive impairment and neuronal cell death in developing animals." | 5.72 | MicroRNA-17-5p Protects against Propofol Anesthesia-Induced Neurotoxicity and Autophagy Impairment via Targeting BCL2L11. ( Gu, X; Liu, C; Luan, H; Xiu, M; Xu, D, 2022) |
| "Propofol, which is a short-acting intravenous anesthetic agent, may have potential as a neuroprotective agent." | 5.37 | Effects of propofol on proliferation and anti-apoptosis of neuroblastoma SH-SY5Y cell line: new insights into neuroprotection. ( Chakraborty, C; Chen, NF; Chen, WF; Hung, HC; Jean, YH; Lee, HP; Sung, CS; Wen, ZH; Wu, GJ, 2011) |
| "This study investigated the role and mechanism of action of propofol on OGD/Rinduced inflammation in mouse N2A neuroblastoma cells." | 3.96 | Propofol Pretreatment Prevents Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-induced Inflammation Through Nuclear Transcription Factor κB (NF-κB) Pathway in Neuroblastoma Cells. ( Hu, F; Jiang, J; Sun, H; Yu, G; Zang, H, 2020) |
| "We have examined the effects of two intravenous anaesthetic induction agents, propofol and thiopentone, on K+ and carbachol evoked [3H]noradrenaline release from a human neuroblastoma cell line, SH-SY5Y." | 3.69 | Effects of propofol and thiopentone on potassium- and carbachol-evoked [3H]noradrenaline release and increased [Ca2+]i from SH-SY5Y human neuroblastoma cells. ( Atcheson, R; Frost, C; Lambert, DG; Rowbotham, DJ; Smart, D; Smith, G; Willets, JM, 1996) |
| "Propofol (PPF) has been shown in studies to cause cognitive impairment and neuronal cell death in developing animals." | 1.72 | MicroRNA-17-5p Protects against Propofol Anesthesia-Induced Neurotoxicity and Autophagy Impairment via Targeting BCL2L11. ( Gu, X; Liu, C; Luan, H; Xiu, M; Xu, D, 2022) |
| "Propofol is an established anesthetic widely used for induction and maintenance of anesthesia." | 1.51 | ( Gao, F; Huang, Y; Li, Y; Lin, H; Liu, J; Peer, J; Tong, Z; Wang, H; Wu, B; Xia, X; Yang, X; Zhao, R; Zheng, JC, 2019) |
| "Propofol treatment reduces intracellular adenosine triphosphate (ATP) production, the mitochondrial respiratory rate, and increases mitochondrial reactive oxygen species production, implying that it disturbs neuronal mitochondrial function." | 1.51 | Propofol induces impairment of mitochondrial biogenesis through inhibiting the expression of peroxisome proliferator-activated receptor-γ coactivator-1α. ( Li, Y; Qin, J; Wang, K, 2019) |
| "Propofol, which is a short-acting intravenous anesthetic agent, may have potential as a neuroprotective agent." | 1.37 | Effects of propofol on proliferation and anti-apoptosis of neuroblastoma SH-SY5Y cell line: new insights into neuroprotection. ( Chakraborty, C; Chen, NF; Chen, WF; Hung, HC; Jean, YH; Lee, HP; Sung, CS; Wen, ZH; Wu, GJ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Xiu, M | 1 |
| Luan, H | 1 |
| Gu, X | 1 |
| Liu, C | 1 |
| Xu, D | 1 |
| Hu, F | 1 |
| Jiang, J | 1 |
| Yu, G | 1 |
| Zang, H | 1 |
| Sun, H | 1 |
| Gao, X | 1 |
| Wang, X | 1 |
| Zhang, L | 1 |
| Liang, G | 1 |
| Mund, R | 1 |
| Wei, H | 1 |
| Liu, J | 1 |
| Li, Y | 2 |
| Xia, X | 1 |
| Yang, X | 1 |
| Zhao, R | 1 |
| Peer, J | 1 |
| Wang, H | 1 |
| Tong, Z | 1 |
| Gao, F | 1 |
| Lin, H | 1 |
| Wu, B | 1 |
| Huang, Y | 1 |
| Zheng, JC | 1 |
| Qin, J | 1 |
| Wang, K | 1 |
| Gu, J | 1 |
| Chi, M | 1 |
| Sun, X | 1 |
| Wang, G | 1 |
| Li, M | 1 |
| Liu, L | 1 |
| Li, X | 1 |
| Nakajima, A | 1 |
| Tsuji, M | 1 |
| Inagaki, M | 1 |
| Tamura, Y | 1 |
| Kato, M | 1 |
| Niiya, A | 1 |
| Usui, Y | 1 |
| Oguchi, K | 1 |
| Wu, GJ | 1 |
| Chen, WF | 1 |
| Hung, HC | 1 |
| Jean, YH | 1 |
| Sung, CS | 1 |
| Chakraborty, C | 1 |
| Lee, HP | 1 |
| Chen, NF | 1 |
| Wen, ZH | 1 |
| Li, Z | 1 |
| Pei, Q | 1 |
| Cao, L | 1 |
| Xu, L | 1 |
| Zhang, B | 1 |
| Liu, S | 1 |
| Cembala, TM | 1 |
| Frost, CL | 1 |
| Atcheson, R | 2 |
| Hirst, RA | 1 |
| Smart, D | 2 |
| Lambert, DG | 2 |
| Willets, JM | 1 |
| Frost, C | 1 |
| Rowbotham, DJ | 1 |
| Smith, G | 1 |
| Friederich, P | 1 |
| Urban, BW | 2 |
| Barann, M | 1 |
| Bönisch, H | 1 |
| Göthert, M | 1 |
13 other studies available for propofol and Neuroblastoma
| Article | Year |
|---|---|
MicroRNA-17-5p Protects against Propofol Anesthesia-Induced Neurotoxicity and Autophagy Impairment via Targeting BCL2L11.
Topics: Anesthesia; Apoptosis; Autophagy; Bcl-2-Like Protein 11; Cell Line, Tumor; Humans; MicroRNAs; Neurob | 2022 |
Propofol Pretreatment Prevents Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-induced Inflammation Through Nuclear Transcription Factor κB (NF-κB) Pathway in Neuroblastoma Cells.
Topics: Animals; Cell Line, Tumor; Cell Survival; Glucose; Inflammation; Interleukin-1beta; Mice; Neuroblast | 2020 |
Sevoflurane But Not Propofol Provided Dual Effects of Cell Survival in Human Neuroblastoma SH-SY5Y Cells.
Topics: Calcium; Cell Survival; Cells, Cultured; Humans; Mitochondria; Neuroblastoma; Presenilin-1; Propofol | 2020 |
Topics: Anti-Inflammatory Agents; Cell Line; Cell Line, Tumor; Culture Media, Conditioned; Culture Media, Se | 2019 |
Propofol induces impairment of mitochondrial biogenesis through inhibiting the expression of peroxisome proliferator-activated receptor-γ coactivator-1α.
Topics: Anesthetics, Intravenous; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Cyclic AMP- | 2019 |
Propofol-induced protection of SH-SY5Y cells against hydrogen peroxide is associated with the HO-1 via the ERK pathway.
Topics: Apoptosis; Cell Line, Tumor; Heme Oxygenase-1; Humans; Hydrogen Peroxide; MAP Kinase Signaling Syste | 2013 |
Neuroprotective effects of propofol on ER stress-mediated apoptosis in neuroblastoma SH-SY5Y cells.
Topics: Apoptosis; Calcium; Calpain; Caspases, Initiator; Cell Line, Tumor; Endoplasmic Reticulum Stress; Eu | 2014 |
Effects of propofol on proliferation and anti-apoptosis of neuroblastoma SH-SY5Y cell line: new insights into neuroprotection.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Dynorphins; Gene | 2011 |
Propofol increases µ-opioid receptor expression in SH-SY5Y human neuroblastoma cells.
Topics: Anesthetics, Intravenous; Cell Line, Tumor; Gene Expression; Humans; Neuroblastoma; Propofol; Recept | 2012 |
Effects of propofol on cAMP and Ins(1,4,5)P3 formation and [3H]noradrenaline uptake and release from SH-SY5Y cells.
Topics: Biological Transport, Active; Carbachol; Cyclic AMP; Humans; Inositol 1,4,5-Trisphosphate; Neuroblas | 1994 |
Effects of propofol and thiopentone on potassium- and carbachol-evoked [3H]noradrenaline release and increased [Ca2+]i from SH-SY5Y human neuroblastoma cells.
Topics: Calcium; Carbachol; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Norepi | 1996 |
The inhibition of human neuronal K+ currents by general anesthetic agents is altered by extracellular K.
Topics: Anesthetics, General; Etomidate; Humans; Ketamine; Membrane Potentials; Neuroblastoma; Neurons; Pota | 1998 |
Inhibition by propofol of 5-HT3 receptors in excised patches of NIE-115 cells.
Topics: Animals; Carbon Radioisotopes; Guanidine; Kinetics; Neuroblastoma; Patch-Clamp Techniques; Propofol; | 1998 |