Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Reference |
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| "Depression is both a common and a greatly undertreated illness in the United States today." | ( Bielski, RJ; Friedel, RO, 1977) |
| "Moderate or severe depression is now one of the most common diseases of our time with a prevalence of nearly 3%." | ( Evans, LE; Whitlock, FA, 1978) |
| "Depression is treated with various medications that may influence function and health of the oral cavity and that may adversely interact with drugs used to control pain and anxiety." | ( Beck, FM; Kaul, TJ; Weaver, JM, 1979) |
| "Lethargy and mental depression are early symptoms, followed by mild parkinsonism and progressive weight loss." | ( Ahmad, D; Barnett, HJ; Bratty, P; Hahn, A; Lloyd, KG; McGeer, EG; Perry, TL; Purdy, A, 1979) |
| "These depressions are primarily pharmacogenic." | ( Kind, J; Müller, P; Steuber, H, 1978) |
| "Depression is evaluated as a final common pathway of potential psychodynamic, genetic, psychosocial, physiological, and personality characteristics or events." | ( Krueger, DW, 1979) |
| "Two cases of depression are presented: One which responded to psychotherapy and the other which responded to medication." | ( Berger, PA; Slater, P; Yesavage, JA, 1979) |
| "Depression is often overlooked, misdiagnosed, or inadequately treated in older patients." | ( Hirschfeld, RM; Klerman, GL, 1979) |
| "Psychogenic depression is characterized by a domination of desynchronized activity of low volts in the EEG and the existence of expressed sympathicotony of the peripheral vegetative system, while statistically significant shifts of the vascular tonus and catecholamine excreation are absent." | ( Biriukovich, PV; Sinitskiĭ, VN; Usherenko, LS, 1978) |
| "Depression is an important cause of behavioral disturbances in children." | ( Brumback, RA; Weinberg, WA, 1977) |
| "Normal depression is characterized by a relative absence of somatic complaints and somatic anxiety." | ( Pincus, C; Prusoff, B; Weissman, MM, 1975) |
| "Depression is among the most common of clinical conditions." | ( Bowden, CL, 1975) |
| "Depression is a common reaction to the vicissitudes of life among elderly people." | ( Fann, WE; Wheless, JC, 1975) |
| "On the other hand, depression is a frequent feature of Cushing's syndrome regardless of etiology, and it is often relieved when the cortisol levels are reduced, by whatever means." | ( Murphy, BE, 1991) |
| "Depression is a potential side effect of antihypertensive drug therapy." | ( Adams, MA; Carr, AA; Fincham, JE; Prisant, LM; Spruill, WJ; Wade, WE, 1991) |
| "Depression is the most common psychiatric condition encountered in elderly people." | ( Aoba, A, 1991) |
| "Since depression is associated with diminished melatonin secretion, the high incidence of TD in patients with history of depression may be linked to diminished secretory activity of the pineal melatonin." | ( Pardeshi, R; Sandyk, R, 1990) |
| "Because depression is often associated with stress, it has been hypothesized that antidepressants may influence stress-related adaptive responses in the brain." | ( Naitoh, H; Nomura, S, 1990) |
| "Depression is a frequent finding in patients with Parkinson's disease (PD)." | ( Andrezejewski, PL; Dannals, RF; Mayberg, HS; Preziosi, T; Robinson, RG; Sadzot, B; Starkstein, SE; Wagner, HN, 1990) |
| "Animal models of depression are important for such investigations." | ( Fonberg, E, 1989) |
| "Although depression is well studied in women, little information is available regarding depression during pregnancy." | ( Amaro, H; Bauchner, H; Cabral, H; Zuckerman, B, 1989) |
| "Of these disorders, depression is the most accessible of these to pharmacological treatment; agitation, however, raises the institutional problem." | ( Cazas, A; Flame, E; Ginestet, D, 1989) |
| "Depression is common in Huntington's disease." | ( Ford, MF, 1986) |
| "Depression is a common and under-recognized problem in the geriatric population." | ( Svenson, J, 1987) |
| "A neurotic depression is a depression in an emotionally unstable person." | ( Black, DW; Nasrallah, A; Winokur, G, 1987) |
| "Depression is a common feature of Parkinson's disease, a fact of both clinical and theoretical significance." | ( Brown, RG; Gotham, AM; Marsden, CD, 1986) |
| "Depression is a major complication of cancer." | ( Costa, D; Mogos, I; Toma, T, 1985) |
| "In five cases this depression is thought to have been responsible for suicide." | ( Carney, MW; De Alarcon, R, 1969) |
| "Depression is a common symptom in patients with Parkinson's disease." | ( Cote, L; Mayeux, R; Stern, Y; Williams, JB, 1984) |
| "Increased rates of depression are reported in alcoholics and in families of alcoholics." | ( O'Sullivan, K, 1984) |
| "Secondary depression is a depression in an individual who has one or more preexisting, nonaffective psychiatric disorders or an incapacitating or life-threatening medical illness which precedes and parallels the symptoms of depression." | ( Clayton, PJ; Lewis, CE, 1981) |
| "An animal model of depression is induced, in rats, by systemic injection of low doses of apomorphine." | ( Foti, D; Giammona, G; Nicoletti, F; Patti, F; Rampello, L; Sortino, MA; Tigano, G, 1983) |
| "Prevalence of depression is high among poor, young, Hispanic inner city women." | ( Tiezzi, L; Westhoff, C; Wieland, D, 1995) |
| "Depression is often associated with insulin resistance, owing to cortisol overproduction; conversely, many studies suggest that diabetics are at increased risk for depression." | ( McCarty, MF, 1994) |
| "Depression is also common in PD, but it is unlikely to occur as a side effect of antiparkinsonian medications." | ( Brown, D; Factor, SA; Molho, ES; Podskalny, GD, 1995) |
| "Many patients with depression are seen only by family physicians, yet it is unknown how their physicians prescribe newer antidepressants." | ( Pritchard, DC; Taylor, AT; Tollison, JW; Wagner, PJ, 1994) |
| "Depression is a common and treatable condition." | ( Lim, HL, 1993) |
| "Depression is not an uncommon complaint of women with breast cancer and is usually assumed to be related to the cancer diagnosis itself or its treatment." | ( Cathcart, CK; Cheek, JH; Jones, SE; Knox, SM; Peters, GN; Pumroy, CS, 1993) |
| "Elderly women with depression are at risk even on a low dosis." | ( Jessurun, AY; Stek, ML, 1995) |
| "Depression is further correlated to a right frontal hyper- and left frontal hypoactivation." | ( Anderer, P; Binder, G; Brandstätter, N; Decker, K; Grünberger, J; Heytmanek, G; Huber, J; Knogler, W; Koll, B; Kurz, C; Linzmayer, L; Metka, M; Saletu, B; Semlitsch, HV; Stamenkovic, M, 1996) |
| "Depression is characterized by blunted DEX/GH responses." | ( Dinan, TG; Thakore, JH, 1996) |
| "Depression is also a major symptom in PD, but the cause is unknown." | ( Charlton, CG, 1997) |
| "Refractory depressions are depressions that respond insufficiently to treatment with the standard antidepressants, given long enough and in adequate dosage." | ( van Praag, HM, 1997) |
| "Depression is common in Alzheimer's disease (AD)." | ( Hashimoto, M; Hirono, N; Ikejiri, Y; Imamura, T; Ishii, K; Mori, E; Sasaki, M; Shimomura, T; Yamashita, H, 1998) |
| "If depression is a state facilitating withdrawal from competition for reproductive success, major depressive illness may be the inappropriate and spontaneous occurrence of a mental state which has advantages for the species in allowing those 'least fit' to fail to survive." | ( Corrigan, FM, 1998) |
| "Although depression is cited in the Norplant contraceptive implant product labeling as a rare side effect, previous evaluations of this association have not included baseline measurement of mood." | ( Cushman, L; Davidson, A; Heartwell, S; Kalmuss, D; Rulin, M; Truman, C; Westhoff, C, 1998) |
| "Depression is common among recently abstinent alcoholics; however, its treatment has been little studied." | ( Roy, A, 1998) |
| "Depression is associated with elevated IFN-gamma and IL-1 beta, downregulated IL-2, and reduced NKA." | ( Holden, RJ; Mooney, PA; Pakula, IS, 1998) |
| "Suicide and depression are associated with an increased density of alpha2-adrenoceptors (radioligand receptor binding) in specific regions of the human brain." | ( Escribá, PV; Eytan, A; García-Sevilla, JA; Guimón, J; La Harpe, R; Ozaita, A; Walzer, C, 1999) |
| "This long-term depression is reversed by bicuculline and potentiated by neurosteroids such as alphaxalone." | ( Akhondzadeh, S; Stone, TW, 1998) |
| "Depression is a highly prevalent concomitant of dementia." | ( Meyers, BS, 1998) |
| "This long-term depression is reversed by bicuculline and potentiated by neurosteroids such as alphaxalone." | ( Akhondzadeh, S; Stone, T, 1999) |
| "Depression is prevalent in patients with diabetes." | ( Clouse, RE; Freedland, KE; Griffith, LS; Lustman, PJ, 2000) |
| "Depression is quite common among young people in Hong Kong Chinese society." | ( Chou, KL, 2000) |
| "Clinical depression is often characterized by a loss of interest or pleasure in formerly enjoyable activities." | ( English, JA; Halaris, A; Paul, IA, 2000) |
| "Depression is a common finding in patients with Parkinson's disease (PD)." | ( Antonini, A; Canesi, M; Mariani, CB; Pezzoli, G; Tesei, S; Zecchinelli, A, 2000) |
| "Depression is a common psychiatric disorder prevalent in 10-15% in general population." | ( Prakash, HM; Sumant, K, 2000) |
| "Depression is common after CHD events, and is associated with smoking and poor NYHA class." | ( Hintikka, J; Koukkunen, H; Laakso, M; Lehto, S; Pyörälä, K; Viinamäki, H, 2000) |
| "Depression is twice as common in women as in men." | ( Young, EA, 1998) |
| "Depression is a major cause of poor nutritional status in older persons." | ( Guigoz, Y; Miller, DK; Morley, JE; Patrick, P; Perry, HM; Vellas, B, 1999) |
| "Depression is a most common psychiatric complication of Parkinson's patients." | ( Miyoshi, K, 2001) |
| "Smoking and depression are related." | ( Carreras, JM; Coll, F; Lores, L; Quesada, M; Sampablo Lauro, I; Sánchez Agudo, L, 2002) |
| "Depression is a common disorder that impacts on all aspects of a person's life." | ( Brunello, N; Kasper, S; Leonard, B; Mendlewicz, J; Montgomery, S; Nelson, J; Paykel, E; Racagni, G; Versiani, M, 2002) |
| "Men with ED and depression are also likely to have other comorbid conditions, including diabetes, hypertension, and heart disease." | ( Fava, M; Gelenberg, AJ; Nurnberg, HG; Rosen, R; Seidman, SN; Shabsigh, R, 2002) |
| "Depression is associated with an increased risk of developing cardiovascular disease and type 2 diabetes mellitus." | ( Ahlberg, AC; Akesson, HO; Björntorp, P; Holm, G; Ljung, T; McEwen, B; Rosmond, R, 2002) |
| "Depression is a common comorbid condition in patients with Tourette's disorder." | ( Annable, L; Dion, Y; Margolese, HC, 2002) |
| "Depression is associated with glucocorticoid abnormalities, in particular a flattening of the diurnal cortisol rhythm." | ( Gartside, SE; Ingram, CD; Leitch, MM; McQuade, R; Young, AH, 2003) |
| "Depression is associated with stroke severity and functional impairment, and with the male sex at 18 months." | ( Berg, A; Kaste, M; Lehtihalmes, M; Lönnqvist, J; Palomäki, H, 2003) |
| "Depression is a common disorder among hospitalized older adults, and it has been associated with adverse outcomes during hospital stays, including increased risk of morbidity and mortality and reduced recovery rates from illness and disability." | ( Atkinson, H; Bernabei, R; Cesari, M; Landi, F; Onder, G; Pahor, M; Penninx, BW, 2003) |
| "Poststroke depression is a frequent psychiatric complication after stroke that may have strong negative impact on rehabilitation therapy and functional recovery." | ( Baumhackl, U; Fruehwald, S; Gatterbauer, E; Rehak, P, 2003) |
| "Depression is a multifactorial illness and genetic factors play a role in its etiology." | ( Adrien, J; Bouali, S; Costentin, J; El Yacoubi, M; Hamon, M; Leroux-Nicollet, I; Naudon, L; Popa, D; Vaugeois, JM, 2003) |
| "Depression is a heritable disorder that is often precipitated by stress." | ( Ahmadiyeh, N; Baum, AE; Redei, EE; Solberg, LC; Takahashi, JS; Turek, FW; Vitaterna, MH, 2003) |
| "Depression is prevalent in people with type 2 diabetes and affects both glycemic control and overall quality of life." | ( Eriksson, JG; Paile-Hyvärinen, M; Wahlbeck, K, 2003) |
| "Depression is a multifaceted psychological disorder that involves changes in behavior, neuroendocrine function, and physiological responses." | ( Beltz, TG; Grippo, AJ; Johnson, AK, 2003) |
| "Depression is characterized by a lack of "motivation" rather than a lack of "physical space" to move around." | ( Alkon, DL; Sun, MK, 2003) |
| "Major depression is a serious disease with various systemic effects, including dysfunction of the immune response." | ( Baccichet, E; Carreira, I; Lima, L; Obregón, F; Peña, S; Urbina, M, 2003) |
| "Depression is present at a frequency of 0." | ( LLOYD, DP; WILSON, VJ, 1957) |
| "Depression is present at a frequency of 0." | ( LLOYD, DP; WILSON, VJ, 1957) |
| "Depression is present at a frequency of 0." | ( LLOYD, DP; WILSON, VJ, 1957) |
| "Depression is present at a frequency of 0." | ( LLOYD, DP; WILSON, VJ, 1957) |
| "Depression is a highly prevalent disorder in the adult population and often worsens the prognosis of comorbid medical illnesses." | ( Miller, A; Musselman, DL; Somerset, WI; Stout, SS, 2003) |
| "Depression is associated with deficiencies in monoaminergic transmitters and possibly neurotrophins." | ( Fang, J; Feng, P; Guan, Z; Yang, X, 2003) |
| "Depression is also a risk factor for poor health outcomes among arthritis patients." | ( Arean, P; Della Penna, R; Harpole, L; Hegel, M; Hoffing, M; Hunkeler, E; Katon, W; Kroenke, K; Langston, C; Lin, EH; Tang, L; Unützer, J; Von Korff, M; Williams, JW, 2003) |
| "Depression is associated with decreased physical functioning and increased morbidity and mortality from cardiovascular disease and cancer." | ( Haight, T; Hollenberg, M; Tager, IB, 2003) |
| "Depression is associated with impaired physical fitness and treadmill exercise performance in older women." | ( Haight, T; Hollenberg, M; Tager, IB, 2003) |
| "Depression is highly prevalent in diabetics and is associated with poor glucose regulation and increased risk of diabetic complications." | ( Anjaneyulu, M; Chopra, K; Kaur, I, 2003) |
| "Depression is the strongest risk factor for late-life suicide and for suicide's precursor, suicidal ideation." | ( Alexopoulos, GS; Brown, GK; Bruce, ML; Katz, II; McAvay, GJ; Mulsant, BH; Pearson, JL; Reynolds, CF; Schulberg, HC; Ten Have, TR, 2004) |
| "Unipolar depression is more common in women than men." | ( Brotchie, HL; Parker, GB, 2004) |
| "Depression is accompanied by a depletion of n-3 poly-unsaturated fatty acids (PUFAs)." | ( Christophe, AB; De Vriese, SR; Maes, M, 2004) |
| "Depression is a widespread and serious disorder that afflicts an estimated 13." | ( Nemeroff, CB; Owens, MJ, 2004) |
| "Depression is not negatively affected by the tested progestins and it may be ameliorated by MPA." | ( Alessandrini, C; Arangino, S; Baldassari, F; Cagnacci, A; Landi, S; Volpe, A, 2004) |
| "Major depression is associated with increased circulating interleukin-2 (IL-2) levels, and IL-2 immunotherapy may provoke depressive symptoms, leading to the suggestion that this cytokine may contribute to the evolution of affective disorders." | ( Anisman, H; Hayley, S; Sudom, K; Turrin, NP, 2004) |
| "Though atypical depression is well documented in younger patients, little attention has been paid to the atypical subtype in samples of late-life depressed patients." | ( Devanand, D; Fitzsimmons, L; Miyazaki, M; Roose, SP; Sackeim, H; Seidman, S; Turret, N, 2004) |
| "Depression is a risk factor for morbidity and mortality in a variety of populations, and anxiety has also been associated with risk of mortality among cardiac patients." | ( Blumenthal, JA; Hughes, JW; Kuhn, C; Sherwood, A; Watkins, L, 2004) |
| "Depression is associated with a dysfunctional serotonin (5-hydroxytryptamine; 5-HT) system." | ( Bae, H; Cho, JH; Hong, M; Jang, CG; Kang, M; Kim, H; Lee, J; Lee, SB; Park, S; Park, SK; Shim, IS; Shin, MK, 2004) |
| "Depression is commonly reported by patients suffering from Obstructive Sleep Apnea Hypopnea Syndrome (OSAS)." | ( Aloia, MS; Arnedt, JT; Millman, RP; Skrekas, J; Smith, L; Stanchina, M, 2005) |
| "Clinical depression is a common yet serious medical condition diagnosed based on the patient's symptoms." | ( Bishop, CE; Carney, L; Gopal, KV, 2004) |
| "Dementia and depression are clinical symptoms commonly associated in patients." | ( Alkon, DL; Sun, MK, 2005) |
| "Depression is a common mental disorder quite prevalent at the primary care level and needs proper identification and prompt treatment." | ( Chowdhury, AN; Ghosh, S; Sanyal, D, 2004) |
| "Depression is a prevalent and recurrent condition among both type 1 and type 2 diabetes." | ( Chowdhury, S, 2004) |
| "Unfortunately, depression is a common side effect of IFN therapy, affecting approximately a third of HCV patients receiving IFN therapy." | ( Blackwell, AD; Turner, EH, 2005) |
| "Depression is a multifactorial and multigenetic disease." | ( Chourbaji, S; Gass, P; Urani, A, 2005) |
| "Worldwide, major depression is the leading cause of years lived with a disability, and the fourth cause of disability-adjusted life years." | ( Han, D; Wang, EC, 2005) |
| "Major depression is the leading cause of disability worldwide, and among the 10 most frequent indications for using alternative medicine therapies, especially dietary supplements." | ( Cotter, A; Girard, C; Goodman, J; Katz, DL; Sabina, A; Williams, AL, 2005) |
| "Thus, although depression is not a uniform accompaniment of the menopausal transition, in some women age-related changes in ovarian estrogen production may alter central nervous system function and predispose them to develop depression." | ( Schmidt, PJ, 2005) |
| "Patients with depression are often excluded from studies on the treatment of social anxiety disorder (SAD), leaving gaps in our knowledge about the impact of depressive affect on treatment for SAD." | ( Davidson, JR; Foa, EB; Huppert, JD; Keefe, FJ; Ledley, DR; Potts, NL, 2005) |
| "Depression is a common disorder among older adults, and it has been associated with adverse outcomes, including increased risk of morbidity and mortality as well as incomplete or delayed recovery from illness and disability." | ( Bandinelli, S; Bartali, B; Cesari, M; Ferrucci, L; Gori, AM; Lauretani, F; Onder, G; Pahor, M; Penninx, BW, 2005) |
| "Depression is common in primary care and it is associated with marked personal, social and economic morbidity, and creates significant demands on service providers in terms of workload." | ( Barbui, C; Brambilla, P; Cipriani, A; Furukawa, T; Geddes, J; Gregis, M; Hotopf, M; Malvini, L, 2005) |
| "Symptoms of depression are present in 40 to 60 percent of patients with epilepsy." | ( Fiszer, U; Grabowska-Grzyb, A; Jedrzejczak, J; Nagańska, E, 2006) |
| "Depression is highly prevalent and frequently recurs in patients with coronary artery disease (CAD) and hypertension." | ( Lopez, LM; Pepine, CJ; Ried, LD; Sauer, BC; Taylor, MD; Tueth, MJ, 2006) |
| "Depression is dramatically underrecognized by oncologists and oncology nurses, and as a result, often undertreated." | ( Donaghy, K; Holtsclaw, E; Kirsh, KL; Passik, SD; Theobald, DE, 2003) |
| "Depression is characterized by symptoms like disturbance in behavior, cognition and mood." | ( Hanim, MA; Rampal, L; Sherina, MS; Thong, PL, 2006) |
| "Pain and depression are often associated." | ( Bach, FW; Gormsen, L; Jensen, TS; Rosenberg, R, 2006) |
| "Although depression is highly prevalent in Parkinson disease (PD), little is known about the neural correlates associated with depression and antidepressant treatment in PD." | ( Barbosa, ER; Bermpohl, F; Buchpiguel, C; Fregni, F; Marcolin, MA; Ono, CR; Pascual-Leone, A; Santos, CM; Valente, KD, 2006) |
| "Since depression is a multifaceted disorder, and a number of symptoms may be present, including circadian rhythm disturbances, we attempted to find the chronobiological abnormalities in CMS rats." | ( Higuchi, S; Morikawa, T; Ohdo, S; To, H; Ushijima, K, 2006) |
| "Depression is a common problem in elderly patients and frequently is treated with antidepressants." | ( Akcay, A; Bavbek, N; Kargili, A; Kaya, A, 2006) |
| "Depression is associated with increased plasma IL-6 concentrations in patients with cancer." | ( Bartholomae, A; Flath, BC; Jehn, CF; Krebs, M; Kuehnhardt, D; Pfeiffer, S; Possinger, K; Regierer, AC; Schmid, P, 2006) |
| "Depression is related to alterations of the monoamine oxidase (MAO), hypothalamic-pituitary-adrenal (HPA) axis, and oxidative systems, and some antidepressants achieve their therapeutic effects through alteration of following biochemical markers of depression: MAO-A and MAO-B activities, cortisol levels, superoxide dismutase (SOD) activity and malondialdehyde (MDA) levels." | ( Chen, Y; Kong, LD; Kung, HF; Pan, Y; Wang, HD; Xia, X, 2007) |
| "Anxiety and depression are currently classified as separate clinical syndromes despite considerable similarities in their symptoms, pathophysiological substrates and response to treatment interventions." | ( Acevedo, EO; Cartwright, CM; Feltenstein, MW; Sufka, KJ; Warnick, JE; Webb, HE, 2006) |
| "Depression is associated with a high rate of morbidity and mortality, and is a leading cause of global disability." | ( Cardinali, DP; Monti, MJ; Pandi-Perumal, SR; Srinivasan, V, 2006) |
| "Depression is associated with medication nonadherence in patients with ACS, but it is unclear whether changes in depression impact on adherence." | ( Burg, MM; Chaplin, WF; Davidson, KW; Gerin, W; Kong, G; Kronish, IM; Lespérance, F; Rieckmann, N, 2006) |
| "Depression is one of the most common neuropsychiatric conditions, with a lifetime prevalence approaching 17%." | ( Abbasi, SH; Akhondzadeh Basti, A; Akhondzadeh, S; Jamshidi, AH; Moshiri, E; Noorbala, AA, 2007) |
| "Major and minor depressions are the two most prevalent forms of acute depressive illness." | ( Rubinow, DR; Schmidt, PJ, 2006) |
| "Depression is commonly experienced among persons with temporal lobe epilepsy (TLE)." | ( Griffith, HR; Hermann, BP; Jones, J; Martin, RC; Paige, AL; Richardson, EJ; Seidenberg, M; Stewart, CC, 2007) |
| "Depression is frequent, underdiagnosed, and untreated in people with epilepsy." | ( Kuczynski, E; Thomé-Souza, MS; Valente, KD, 2007) |
| "IFN-alpha-induced depression is presumed to be composed of two overlapping syndromes: a depression-specific syndrome characterized by depressed mood, anxiety, and cognitive complaints, and a neurovegetative syndrome consisting of fatigue, anorexia, somatic pain complaints, and psychomotor retardation [1]." | ( Balan, V; Krahn, LE; Martin, KA; Rosati, MJ, 2007) |
| "Fatigue and depression are common symptoms of chronic HCV infection that may also be caused by IFN-based therapy." | ( Kallman, J; Kincaid, J; Younossi, Z, 2007) |
| "Depression is a frequent comorbidity in epilepsy patients." | ( Auvin, S; Caplan, R; Mazarati, A; Sankar, R; Shin, D, 2007) |
| "Depression is associated with an increased risk for cardiac morbidity and mortality in patients with coronary heart disease (CHD)." | ( Carney, RM; Duntley, SP; Freedland, KE; Miller, GE; Rich, MW; Stein, PK; Steinmeyer, B, 2007) |
| "Depression is associated with hippocampal plasticity, for which increased excitatory amino acid (EAA) release in CA3 induced by chronic stress is responsible, and glucocorticoids have a permissive role and act synergistically with EAAs in producing neuronal damage." | ( Han, H; Hou, HL; Tong, H; Wang, QN; Wu, LM; Yan, XB; Zhou, JN, 2007) |
| "Major depression is a highly prevalent mental disorder and environmental factors have been strongly implicated in its pathophysiology." | ( Hashimoto, R; Hattori, S; Kunugi, H; Maeno, H; Miyakawa, T; Wada, K; Yamanaka, H, 2007) |
| "In fact, depression is the most common neuropsychiatric disorder associated with epilepsy, particularly temporal lobe epilepsy, and individuals with a history of depression are at a higher risk for developing epilepsy than the general population." | ( Boss-Williams, KA; Tabb, K; Weinshenker, D; Weiss, JM, 2007) |
| "The incidence of depression is believed to be greater in patients with EOPD than with the late-onset form of the disease, although there is no risk factor or marker for depression in patients with PD." | ( Bertucci Filho, D; Teive, HA; Werneck, LC, 2007) |
| "Depression is common in hepatitis C, exacerbated by interferon, and is a major reason for discontinuing interferon therapy." | ( Fucci, JC; Gleason, OC; Philipsen, MA; Yates, WR, 2007) |
| "Depression is more prevalent among women than among men." | ( Jansen, BJ; Kooiman, LA; Peeters, FP, 2007) |
| "Depression is a major public health problem in the United States and is responsible for an enormous economic burden and loss of productivity and quality of life." | ( Collins, RL; Escobar, JI, 2006) |
| "Furthermore, depression is associated with stress hormone dysregulation and bidirectional interactions are thought to occur between stress-related changes in the neuroendocrine stress system and the 5-HT system." | ( Firk, C; Markus, CR, 2007) |
| "Depression is frequently observed in patients with heart failure and is associated with poor quality of life and adverse prognosis." | ( Cines, M; Gottlieb, SS; Greenberg, N; Katzen, S; Kop, WJ; Marshall, J; Minshall, S; Thomas, SA; Vesely, MR, 2007) |
| "Depression is a well-defined illness that afflicts a large population worldwide." | ( Chopra, K; Kaur, R; Singh, D, 2007) |
| "Depression is prevalent in people with type 2 diabetes and affects both glycaemic control and overall quality of life." | ( Eriksson, JG; Paile-Hyvärinen, M; Wahlbeck, K, 2007) |
| "Depression is a feature of both Lewy body disorders and multiple system atrophy (MSA)." | ( Benarroch, EE; Low, PA; Parisi, JE; Sandroni, P; Schmeichel, AM, 2007) |
| "Depression is a common co-morbid condition in patients with cardiac disease and has been identified as an independent risk factor for increased morbidity and mortality." | ( Fountoulaki, K; Kremastinos, DT; Paraskevaidis, I; Parissis, J, 2007) |
| "Depression is a common disorder in the elderly handicapping patients with affective and cognitive symptoms." | ( Böhringer, A; Müller, SE; Savaskan, E; Schächinger, H; Schulz, A, 2008) |
| "Depression is the most common psychiatric complication in Parkinson's disease (PD)." | ( Juckel, G; Klein, J; Kupsch, A; Lee, T; Morgenstern, R; Mundt, A; Petrus, D; von Rumohr, A; Winter, C, 2007) |
| "The theory of depression is dominated by the monoamine hypothesis but there is increasing evidence that beyond monoamines, glutamate (Glu) and gamma-aminobutyric acid (GABA) play an essential role in the pathogenesis of depression." | ( Ende, G; Henn, FA; Mahlstedt, MM; Sartorius, A; Vollmayr, B, 2007) |
| "Depression is common among patients with chronic heart failure (CHF) and has been independently associated with a poorer prognosis." | ( Adamopoulos, S; Bistola, V; Farmakis, D; Filippatos, G; Kremastinos, DT; Nikolaou, M; Paraskevaidis, IA; Parissis, JT, 2008) |
| "Depression is one of the most common, but still not clearly defined, emotional reactions in adolescence." | ( Nishimura, R, 2007) |
| "Anxiety and depression are among the most frequently-observed psychiatric symptoms associated with nicotine (NC)." | ( Hayase, T, 2007) |
| "Depression is a risk factor for cardiovascular disease (CVD) perhaps mediated by hypothalamic-pituitary-adrenal (HPA) axis or vagal dysregulation." | ( Conrad, A; Roth, WT; Spiegel, D; Taylor, CB; Wilhelm, FH, 2008) |
| "Depression is relatively common in patients with coronary heart disease (CHD) and is associated with worse prognosis." | ( Babyak, MA; Blumenthal, JA; Doraiswamy, PM; Hinderliter, A; Hoffman, BM; Johnson, JJ; O'Connell, C; Patidar, SM; Rogers, SD; Sherwood, A; Watkins, L; Waugh, R, 2007) |
| "Depression is a debilitating mood disorder that is among the top causes of disability worldwide." | ( Shevchuk, NA, 2008) |
| "Because depression is closely related to anxiety disorders, and because it has been suggested that stress may be associated with an elevated homocysteine level, we studied whether serum homocysteine levels are elevated in patients with posttraumatic stress disorder (PTSD)." | ( Dwolatzky, T; Kaplan, Z; Kotler, M; Levine, J; Roitman, S; Sela, BA; Spivak, B; Timinsky, I; Vishne, T, 2008) |
| "Depression is a common mental health problem often seen in primary care." | ( Abraham, S; Jacob, KS; Jeyabalan, S; Kuruvilla, A; Prasad, J, 2007) |
| "Depression is poorly recognized and undertreated in patients following ACS, but progress is being made in developing abbreviated measurement tools that can be used in clinical cardiologic practice." | ( Steptoe, A; Williams, ED, 2007) |
| "Depression is one of the most common psychiatric disturbances in Parkinson's disease (PD)." | ( Bordet, R; Cottencin, O; Defebvre, L; Destée, A; Devos, D; Dujardin, K; Moreau, C; Poirot, I; Thomas, P, 2008) |
| "Depression is a pathological state of mood and is considered as one of the major causes of disabilities." | ( Furuse, M; Morimatsu, F; Onitsuka, E; Sato, M; Takahata, Y; Tomonaga, S; Yamada, S; Yamane, H, 2008) |
| "Although depression is often associated with a reduction in cellular immune responses, other types of emotional disturbance and psychopathology can activate certain aspects of immunity." | ( Carnes, M; Coe, CL; Lemieux, A, 2008) |
| "Psychotic depression is classified as a clinical subtype of major depressive disorder." | ( Papadimitriou, GN; Politis, AM; Psarros, C; Soldatos, CR; Theleritis, CG, 2008) |
| "Depression is a disease of growing incidence and economic burden worldwide." | ( Ebinger, M; Ivan, D; Schneider, HJ; Sievers, C; Stalla, GK, 2009) |
| "Depression is diagnosed in 15-30% of patients following myocardial infarction (MI) and this may also be observed in the rat." | ( Bah, TM; Boucher, M; Dufort, AM; Godbout, R; Kaloustian, S; Le Marec, N; Rousseau, G; Wann, BP, 2009) |
| "Depression is a common problem in the elderly, and the recognition and appropriate management of this illness are important aspects of geriatric medicine." | ( Cheah, CY; Fegan, PG; Ladhams, B, 2008) |
| "The risk of depression is increased in many medical and surgical conditions." | ( de Silva, V; Hanwella, R, 2008) |
| "Prevalence of depression is 67." | ( Al-Jawad, M; Narayan, KA; Rashid, AK, 2007) |
| "Depression is a frequent side effect of interferon therapy in patients with chronic hepatitis C (CHC)." | ( Back-Madruga, C; Bieliauskas, LA; Fontana, RJ; Kronfol, Z; Lindsay, KL; Lok, AS; Padmanabhan, L; Stoddard, AM, 2008) |
| "Depression is associated with a deficiency of serotonergic neurons that have been found to suppress orexinergic neurons, which in turn activate these neurons in a feedback loop." | ( Feng, P; Hu, Y; Strohl, KP; Vurbic, D; Wu, Z, 2008) |
| "Depression is common - one-fourth of the U." | ( Miller, AL, 2008) |
| "Major depression is prevalent among postpubertal females, and is associated with perturbations in social attachments, dysregulation of the hypothalamic-pituitary-adrenal stress axis, and elevated levels of anxiety." | ( Amico, JA; Cai, HM; Cyranowski, JM; Frank, E; Hofkens, TL; Seltman, H, 2008) |
| "Depression is a common symptom in patients suffering from Parkinson's disease (PD) and markedly reduces their quality of life." | ( Barthel, H; Hesse, S; Isaias, IU; Meyer, PM; Oehlwein, C; Sabri, O; Schwarz, J; Strecker, K; Wegner, F, 2009) |
| "Depression is one of the frequently-observed psychiatric symptoms associated with nicotine (NC) use." | ( Hayase, T, 2008) |
| "Depression is associated with an increased risk of cardiovascular disease (CVD), coronary heart disease (CHD) and cardiac death." | ( Jokinen, J; Nordström, P, 2009) |
| "Depression is a risk factor for the development of coronary heart disease but the relationship between coronary endothelial dysfunction and depression is not yet known." | ( Choi, CU; Kim, EJ; Kim, JH; Kim, JW; Ko, YH; Na, JO; Oh, DJ; Park, CG; Rha, SW; Seo, HS, 2010) |
| "Depression is frequently reported in epilepsy patients; however, mechanisms of co-morbidity between epilepsy and depression are poorly understood." | ( Bragin, A; Kwon, YS; Mazarati, AM; Pineda, E; Sankar, R; Shin, D; Taylor, AN; Tio, D, 2009) |
| "Depression is found in 40 to 50% of these patients and is associated with a variety of poor outcomes for both patients and their families." | ( Bienfait, K; Buyske, S; Dicke, A; Dobkin, RD; Gara, M; Marin, H; Mark, MH; Menza, M, 2009) |
| "Postmenopausal depression is more severe, has a more insidious course, is more resistant to conventional antidepressants in comparison with premenopausal women and has better outcomes when antidepressants are combined with HT." | ( Graziottin, A; Serafini, A, 2009) |
| "Depression is common among patients with CVD and is associated with failure to follow recommendations to reduce cardiac risk." | ( Rigotti, NA; Thorndike, AN, 2009) |
| "Depression is associated with adverse prognosis in cardiac patients, warranting the availability of brief and valid instruments to identify depressed patients in clinical practice." | ( de Jonge, P; Denollet, J; Pedersen, SS; Serruys, PW; Simsek, C; van Domburg, RT, 2009) |
| "Whether preclinical depression is one of the pathophysiologic features of Alzheimer disease (AD) has been under debate." | ( Futatsubashi, M; Nakamura, K; Ouchi, Y; Ueki, T; Yagi, S; Yoshikawa, E, 2009) |
| "Depression is the primary emotional condition for which help is sought." | ( Andrews, PW; Thomson, JA, 2009) |
| "One hypothesis of depression is that it is caused by reduced neuronal plasticity including hippocampal neurogenesis." | ( Bjørnebekk, A; Brené, S; Mathé, AA, 2010) |
| "Depression is experienced as a persistent low mood or anhedonia accompanied by behavioural and cognitive disturbances which impair day to day functioning." | ( Ashburner, J; Chu, C; Costafreda, SG; Fu, CH, 2009) |
| "Anxiety and depression are often also present." | ( , 2009) |
| "Depression is regarded as one of the widespread psychiatric diseases." | ( Al-Hazmi, S; Maimanee, TA, 2009) |
| "Depression is a well-known risk factor for cardiovascular disease and mortality." | ( Bosch, NM; Dietrich, A; Oldehinkel, AJ; Ormel, J; Riese, H; Verhulst, FC, 2009) |
| "Thus, although depression is not a uniform accompaniment of the menopause transition, in some women, age-related changes in ovarian estrogen production may alter central nervous system function and predispose them to develop depression." | ( Rubinow, DR; Schmidt, PJ, 2009) |
| "Depression is one of the most common psychiatric disorders that affects over 10% of individuals." | ( Chen, PJ; Chiang, HM; Hou, YC; Hsieh, CL; Sheen, LY; Su, KP, 2009) |
| "Tobacco smoking and depression are strongly associated, but the possible effects of SHS have not been evaluated." | ( Arheart, KL; Bandiera, FC; Caban-Martinez, AJ; Davila, EP; Dietz, NA; Fleming, LE; Leblanc, WG; Lee, DJ; Lewis, JE; McCollister, K; Serdar, B, 2010) |
| "Depression is one of the most prevalent mental health conditions and can affect people of all ages, but it is becoming more common among the older population with increasing life expectancy." | ( Williamson, C, 2009) |
| "Depression is a common problem in patients with Delayed Sleep Phase Syndrome (DSPS)." | ( Kayumov, L; Rahman, SA; Shapiro, CM, 2010) |
| "Depression is common in Alzheimer disease (AD), and antidepressants are commonly used for its treatment, however, evidence for antidepressant efficacy in this population is lacking." | ( Drye, LT; Frangakis, C; Lyketsos, CG; Martin, BK; Meinert, CL; Mintzer, JE; Munro, CA; Porsteinsson, AP; Rabins, PV; Rosenberg, PB; Schneider, LS; Weintraub, D, 2010) |
| "Depression is a leading cause of disability worldwide and depressive symptoms are common in later life." | ( Almeida, OP; Fenner, S; Flicker, L; Ford, AH; Hegarty, S; Hirani, V; McCaul, K; van Bockxmeer, F, 2010) |
| "Depression is associated with dysregulated hypothalamic-pituitary-adrenal (HPA) axis function, overactivity of the sympathoadrenal system, and increased levels of inflammation markers." | ( Bonsall, RW; Deuster, PA; Francis, JL; Kop, WJ; Tracy, RP; Weinstein, AA, 2010) |
| "Major depression is more prevalent among women than men, and progesterone might be involved in the mechanisms that generate these differences." | ( Andrade, S; Arbo, BD; Barros, HM; Batista, BA; Gomez, R; Ribeiro, MF; Silveira, SL, 2010) |
| "Depression is a common illness with severe morbidity and mortality." | ( Akar, FY; Erden, BF; Komsuoglu, FI; Mutlu, O; Tanyeri, P; Ulak, G, 2010) |
| "Depression is common in early phases of Alzheimer's disease (AD) and may represent prodromal symptoms of dementia." | ( Colaianna, M; Cuomo, V; Govoni, S; Morgese, MG; Schiavone, S; Trabace, L; Tucci, P; Zotti, M, 2010) |
| "Depression is a critical cause of child abuse and neglect, and it has been reported that maternal behavior involves dopaminergic neurons of the mesolimbic pathway." | ( Nakagawasai, O; Niijima, F; Onogi, H; Sato, A; Tadano, T; Tan-No, K, 2010) |
| "Depression is a common psychiatric disorder affecting individuals across the life span." | ( Chang, RC; Law, AC; Wuwongse, S, 2010) |
| "Depression is a frequent non-motor symptom in Parkinson's disease (PD) with increasing rates with the progression of the disease." | ( Amaro-Junior, E; Andrade, LA; Borges, V; Bressan, RA; Felicio, AC; Ferraz, HB; Godeiro-Junior, C; Hoexter, MQ; Moriyama, TS; Shih, MC; Silva, SM, 2010) |
| "depression is common in elderly people and may be associated with increased cardiovascular risk and incident dementia." | ( Beckett, N; Bulpitt, C; Fletcher, A; Grimley-Evans, J; McCormack, T; Nunes, M; Peters, R; Pinto, E; Potter, J; Swift, C, 2010) |
| "Depression is a frequently encountered non-motor feature of Parkinson's disease (PD) and it can have a significant impact on patient's quality of life." | ( Andreatini, R; Barbieiro, J; Dombrowski, PA; Lima, MM; Santiago, RM; Vital, MA, 2010) |
| "Depression is highly prevalent in individuals with advanced kidney disease, but is less well studied in individuals with milder disease." | ( Fried, LF; Leak, TS; Minev, E; Newman, AB; Shlipak, MG; Simsonick, E; Unruh, M; Yaffe, K, 2010) |
| "Depression is a common condition in the community with a significant impact on affected individuals, their relatives and society." | ( Aguglia, E; Caraci, F; Drago, F; Forti, B; Kasper, S, 2010) |
| "Depression is common among people with diabetes and it is associated with poor outcomes." | ( Bhansali, A; Dhanaraj, E; Grover, S; Raval, A; Tiwari, P, 2010) |
| "Depression is common among HF patients." | ( Arias, RM; Callwood, DD; Cuffe, MS; Jiang, W; Krishnan, R; Kuchibhatla, M; O'Connor, CM; Rivelli, SK; Silva, SG; Stough, WG; Zakhary, B, 2010) |
| "Depression is a common comorbidity in heart failure (HF); however, the mechanisms related to a poorer outcome of depressed patients with HF remain unclear." | ( Aguiar, VB; Cardoso, JN; Del Carlo, CH; Morgado, PC; Munhoz, RT; Ochiai, ME; Pereira-Barretto, AC, 2010) |
| "Major depression is a chronic, recurring and potentially life-threatening illness that affects up to 10% of the population worldwide." | ( Branchi, I, 2011) |
| "Tobacco use and depression are highly prevalent among methadone maintenance (MM) treatment programme participants." | ( Arnold, S; Gandhi, D; Joshi, A; Khanna, N; Sadaphal, S; Stewart, D, 2010) |
| "Prenatal depression is a public health concern." | ( Avison, WR; Campbell, MK; Evers, SE; Roy, A, 2010) |
| "Depression is a very prevalent mental disorder affecting 340 million people globally and is projected to become the leading cause of disability and the second leading contributor to the global burden of disease by the year 2020." | ( Dinas, PC; Flouris, AD; Koutedakis, Y, 2011) |
| "Depression is a common psychological symptom in patients undergoing chronic hemodialysis." | ( Afshariani, R; Ghanizadeh, A; Hamidian Jahromi, A; Kashfi, M; Roozbeh, J; Sagheb, MM; Sahraian, A; Shabani, S; Sharifian, M, 2011) |
| "Clinical depression is associated with both anhedonia and cognitive impairments." | ( Andreasen, JT; Bate, S; Christiansen, S; Henningsen, K; Wiborg, O, 2011) |
| "Depression is a major psychiatric disorder affecting nearly 21% of the world population and imposes a substantial health burden on society." | ( Liu, C; Ma, F; Pan, F; Shi, D; Zhang, Y; Zheng, M, 2011) |
| "Clinical depression is accompanied by lowered levels of neuroprotective TRYCATs or increased levels or neurotoxic TRYCATs, and lowered plasma tryptophan, which is associated with indices of immune activation and glucocorticoid hypersecretion." | ( Kubera, M; Leonard, BE; Maes, M; Myint, AM; Verkerk, R, 2011) |
| "Depression is a common disorder among diabetic patients and affects negatively the treatment of their basic disease." | ( Beran, J; Jankovec, Z; Komorousova, J; Rusavy, Z, 2010) |
| "Depression is the most common neuropsychiatric co-morbidity in Parkinson's disease (PD)." | ( Hartung, H; Sharp, T; Tan, SK; Temel, Y, 2011) |
| "Depression is associated with nutritional deterioration in older persons and is highly prevalent among people of low socioeconomic status (LSES)." | ( Fraser, D; German, L; Kahana, C; Rosenfeld, V; Shahar, DR; Wiezer, Z; Zabrowsky, I, 2011) |
| "Depression is prevalent in patients with heart failure and is associated with a significant increase in hospitalizations and death." | ( Arias, RM; Cuffe, MS; Jiang, W; Krishnan, R; Kuchibhatla, M; Martsberger, C; O'Connor, CM, 2011) |
| "Depression is a common problem in patients with multiple sclerosis (MS)." | ( De Keyser, J; Glazenborg, A; Koch, MW; Mostert, J; Uyttenboogaart, M, 2011) |
| "Depression is independently associated with poor outcomes among patients with acute cardiac disease." | ( Fricchione, GL; Healy, BC; Huffman, JC; Januzzi, JL; Mastromauro, CA; Sowden, G, 2011) |
| "Depression is recognized as a predictor of increased cardiac morbidity and mortality." | ( Belzung, C; Camus, V; d'Audiffret, A; Isingrini, E, 2011) |
| "Depression is common in schizophrenia and worsens its course." | ( Burkin, M; Joffe, G; Joffe, M; Stenberg, JH; Tchoukhine, E; Terevnikov, V; Tiihonen, J, 2011) |
| "Depression is associated with hippocampus (HC) volume loss." | ( First, M; Gil-Ad, I; Novak, N; Taler, M; Tarasenko, I; Weizman, A, 2011) |
| "Depression is common among college students and higher levels of depression are associated with greater alcohol-related problems." | ( Gonzalez, VM; Reynolds, B; Skewes, MC, 2011) |
| "Because depression is so common in patients with medical illness, assessing whether a medication has in fact caused depression, or whether the relationship is coincidental, can be challenging." | ( Caro, MA; Celano, CM; Fernandez-Robles, C; Freudenreich, O; Huffman, JC; Stern, TA, 2011) |
| "Major depression is an independent risk factor for the development of cardiovascular disease." | ( Belzung, C; Camus, V; d'Audiffret, A; Freslon, JL; Frisbee, J; Isingrini, E; O'Donnell, J; Surget, A, 2011) |
| "Depression is a stress related disease, as hormones of the stress-axis can modify mood." | ( Domokos, Á; Mergl, Z; Mikics, É; Pintér, O; Zelena, D, 2011) |
| "Subclinical depression is associated with higher stress but less reward from social contacts." | ( Birmingham, W; Holt-Lunstad, J; Light, KC, 2011) |
| "Depression is highly common throughout the life course and dementia is common in late life." | ( Byers, AL; Yaffe, K, 2011) |
| "Depression is common in patients with coronary artery disease (CAD) and is associated with higher risk of cardiovascular adverse events." | ( Anastasiou-Nana, M; Apostolou, T; Charalampopoulos, A; Dagres, N; Kotakos, C; Liakos, G; Rallidis, LS; Sourides, V; Varounis, C, 2011) |
| "Mild depression is associated with increased cardiovascular mortality and is a better predictor than CRP levels in patients with stable CAD." | ( Anastasiou-Nana, M; Apostolou, T; Charalampopoulos, A; Dagres, N; Kotakos, C; Liakos, G; Rallidis, LS; Sourides, V; Varounis, C, 2011) |
| "Depression is a common mental disorder; however, its molecular mechanism has not been fully elucidated." | ( Peng, S; Zhang, S; Zhang, X; Zhu, X, 2011) |
| "Depression is most commonly associated with epilepsy." | ( Citraro, R; Constanti, A; De Fazio, S; De Sarro, G; Di Paola, ED; Perrota, I; Perrotta, I; Russo, E; Scicchitano, F, 2011) |
| "Geriatric depression is associated with heart disease, high cholesterol blood levels, marital status, and daily inactivity." | ( Allegri, RF; Dillon, C; Machnicki, G; Rojas, G; Serrano, CM; Vazquez, G, 2011) |
| "Depression is associated with an increased risk of cardiovascular disease, but the association with dietary habits is not well understood." | ( Kalogeropoulos, N; Kastorini, CM; Mamplekou, E; Panagiotakos, DB; Papadimitriou, GN; Papageorgiou, C; Pitsavos, C; Stefanadis, C, 2010) |
| "Depression is one of the most pervasive and debilitating psychiatric diseases, and the molecular mechanisms underlying the pathophysiology of depression have not been elucidated." | ( Ding, ZB; Jiang, WG; Li, QQ; Lu, L; Shi, HS; Wang, SJ; Wang, X; Wu, P; Xu, CM; Zhu, WL, 2012) |
| "Depression is associated with mucosal proinflammatory cytokines in patients with pouchitis after restorative proctocolectomy in patients with UC." | ( Häuser, W; Schmidt, C; Stallmach, A, 2011) |
| "Major depression is a frequent adverse effect of interferon-alpha (IFN-α) therapy." | ( de Oliveira, IR; Galvão-de Almeida, A; Guindalini, C; Koenen, KC; Lyra, AC; Miranda-Scippa, A; Paraná, R; Parise, CL; Quarantini, LC; Sampaio, AS, 2011) |
| "Stress-induced depression is a kind of functional and structural disability of the brain and involves many neurotransmitters and regions of the brain." | ( An, SC; Gu, CY, 2011) |
| "Depression is a prevalent complex psychiatric disorder and its pathophysiological mechanism is not yet well understood." | ( Du, G; Gao, X; Guo, X; Li, Z; Qin, X; Sun, H; Zhang, L; Zheng, X; Zhou, Y, 2011) |
| "Depression is the most common psychiatric disorder in Huntington's disease (HD) patients." | ( Chevarin, C; Du, X; Hannan, AJ; Lanfumey, L; Leang, L; Pang, TY; Renoir, T; Zajac, MS, 2011) |
| "Depression is a significant public health problem." | ( Bailey, K; Lai, J; McEvoy, M; Moxey, A; Nowak, G; Vashum, K, 2012) |
| "Depression is a major health problem worldwide." | ( Alvarado, G; Artigas, F; Bortolozzi, A; Carmona, MC; Castañé, A; Cortés, R; Fernández, G; Ferrés-Coy, A; Montefeltro, A; Perales, JC; Santana, N; Semakova, J; Toth, M, 2012) |
| "Smoking and depression are each associated with inflammation and vagal tone." | ( Fischer, JE; Herr, RM; Lane, RD; Loerbroks, A; Taylor, L; Thayer, JF, 2011) |
| "The incidence of depression is expected to increase over the next 20 years, and many people will have to deal with it." | ( Aazami, S; Yary, T, 2011) |
| "Depression is a common comorbid condition in patients with chronic heart failure (CHF)." | ( Andreadou, I; Antonellos, N; Douzenis, A; Ikonomidis, I; Kremastinos, D; Lykouras, E; Markantonis-Kiroudis, S; Michalakeas, CA; Nikolaou, M; Paraskevaidis, I; Parissis, JT; Varounis, C, 2011) |
| "Depression is a significant public health problem and some reports indicate an association between depression and endoplasmic reticulum stress." | ( Hara, H; Ishisaka, M; Kakefuda, K; Shimazawa, M; Tsuruma, K; Tsuruta, A; Yamauchi, M, 2011) |
| "Anxiety and depression are considered as stress-related disorders, which present considerable sex differentiation." | ( Antoniou, K; Dalla, C; Dendi, A; Kokras, N; Mikail, HG; Papadopoulou-Daifoti, Z; Sideris, AC, 2012) |
| "Depression is a disorder that can be classified in the categories of non-organic psychiatric disorders and mood disorders." | ( Capasso, A; Caputo, M; Monteleone, F; Tecce, MF, 2011) |
| "Depression is characterized by IgM-related autoimmune responses directed against a) neoepitopes that are normally not detected by the immune system but that due to damage by O&NS have become immunogenic; and b) anchorage epitopes, i." | ( Geffard, M; Kubera, M; Leunis, JC; Maes, M; Mihaylova, I, 2011) |
| "Depression is an important cause of morbidity, and World Health Organization has predicted that it will be the second leading contributor to the global burden of disease by 2020." | ( Aazami, S; Yary, T, 2012) |
| "Depression is a common occurrence in patients with Parkinson's disease (PD)." | ( Hamaguchi, H; Kanda, F; Sekiguchi, K; Yasui, N, 2011) |
| "Major depression is a common diagnosis in older individuals." | ( Fischer, CE; Herrmann, N; Jiang, D; Joy, J; Ringer, L; Schweizer, TA, 2011) |
| "Depression is frequent in Parkinson's disease, but its pathophysiology remains unclear." | ( Ballanger, B; Broussolle, E; Eche, J; Klinger, H; Le Bars, D; Lerond, J; Sgambato-Faure, V; Thobois, S; Tremblay, L; Vallet, AE, 2012) |
| "Depression is a major health concern in India, yet indigenous Indian perspectives on depression have often been disregarded in favor of Western conceptualizations." | ( Birgenheir, DG; Maack, DJ; Nieuwsma, JA; Pepper, CM, 2011) |
| "In conclusion, depression is very frequent in mastocytosis patients and masitinib therapy is associated with the reduction its psychic experiences." | ( Barete, S; Damaj, G; Georgin-Lavialle, S; Gineste, P; Hermine, O; Lortholary, O; Montestruc, F; Moura, DS; Moussy, A; Pillet, N; Sultan, S, 2011) |
| "In humans, depression is associated with altered rapid eye movement (REM) sleep." | ( Huang, ZL; Li, R; Qu, WM; Tu, ZC; Urade, Y; Wang, YQ; Xu, XY, 2012) |
| "Memory deficits and depression are common in patients with temporal lobe epilepsy (TLE)." | ( Appel, S; Dustin, IH; Khan, OI; Martinez, AR; Reeves-Tyer, P; Sato, S; Theodore, WH; Wiggs, EA, 2012) |
| "Depression is frequently comorbid with a drug addiction and may seriously complicate its treatment." | ( Dusek, L; Kucerova, J; Pistovcakova, J; Sulcova, A; Vrskova, D, 2012) |
| "depression is characterized by a stable negative bias toward emotional stimuli." | ( Dai, Q; Feng, Z; Ji, B; Liao, C; Wang, X; Xie, B; Zhou, D, 2012) |
| "Apathy and depression are among the most common psychiatric and behavioral disorders associated with Parkinson's disease (PD)." | ( Kostic, VS; Petrovic, M; Stefanova, E; Stojkovic, T; Ziropadja, Lj, 2012) |
| "Depression is a major problem in patients after acute coronary syndrome (ACS) with negative impact on survival and quality of life." | ( Andersen, NL; Birket-Smith, M; Hanash, JA; Hansen, BH; Hansen, JF; Nielsen, OW; Rasmussen, A, 2012) |
| "Depression is a prevalent psychological problem in PD population." | ( Ahn, C; Joo, KW; Kim, DK; Kim, YS; Lee, H; Lee, JP; Lim, CS; Oh, KH; Oh, YK; Park, HC, 2012) |
| "Depression is associated with medical comorbidities, particularly cardiovascular disease." | ( Bhatnagar, S; Grigoriadis, D; McFadden, KV; Valentino, RJ; Wood, SK, 2012) |
| "Depression is a disabling condition which adversely affects a person's family, social and work life, and that is associated with a heavy burden to society." | ( Bellantuono, C; Catena-Dell'Osso, M; Marazziti, D; Rotella, F, 2012) |
| "Depression is a frequent comorbid disorder in Parkinson's disease (PD) which may precede appearance of its motor symptoms by several years." | ( Berghauzen, K; Dziubina, A; Gołembiowska, K; Kolasiewicz, W; Kuter, K; Ossowska, K; Schulze, G; Wardas, J, 2011) |
| "Depression is usually associated with alterations in the monoaminergic system." | ( De Bundel, D; Gómez-Galán, M; Lindskog, M; Smolders, I; Van Eeckhaut, A, 2013) |
| "Depression is the most common psychiatric disorder." | ( Aricioglu, F; Utkan, T; Yazir, Y, 2012) |
| "While depression is a syndrome with multiple possible etiologies, we propose that a disruption in glutamatergic neurotransmission may underline a substantial proportion of clinically observed depression." | ( Alexander, R; Kanes, S; Lee, CM; McCarthy, DJ; Pathak, S; Sanacora, G; Smith, MA, 2012) |
| "Depression is associated with systemic inflammation, and the systemic inflammation caused by endotoxin administration elicits mild depressive symptoms such as fatigue and reduced interest." | ( Carson, RE; Dellagioia, N; Hannestad, J; Pittman, B; Planeta-Wilson, B; Subramanyam, K; Weinzimmer, D, 2012) |
| "Depression is a complex psychiatric disorder characterized by anhedonia and feeling of sadness and chronic mild stress (CMS) seems to be a valuable animal model of depression." | ( Hemanth Kumar, BS; Khushu, S; Mishra, SK; Rana, P; Singh, S, 2012) |
| "Depression is one of the most common symptoms of menopausal syndrome, and is currently treated with estrogen replacement and antidepressant therapy." | ( Cai, SQ; Ku, BS; Liu, SL; Ma, XQ; Wang, CZ; Wang, YF; Xu, ZK; Yang, DH; Yao, HY, 2013) |
| "Depression is a clinically heterogenous condition defined by sub-types that can have diametrically opposed features, such as sleep and appetite." | ( Dinan, TG; Frodl, T; O'Keane, V, 2012) |
| "Depression is characterized by low reward sensitivity in behavioral studies applying signal detection theory." | ( Kunisato, Y; Okada, G; Okamoto, Y; Onoda, K; Samejima, K; Suzuki, S; Ueda, K; Yamawaki, S; Yoshimura, S, 2012) |
| "Major depression is a mental disorder often preceded by exposure to chronic stress or stressful life events." | ( Elizalde, N; García-García, AL; Tordera, RM; Venzala, E, 2013) |
| "Depression is a debilitating mental illness and is often comorbid with metabolic disorders such as type 2 diabetes." | ( Cheng, SY; Ding, J; Guo, M; Liu, F; Liu, J; Liu, M; Lu, XY; Scherer, PE; Zhang, D, 2012) |
| "Depression is a major complication during treatment of chronic hepatitis C virus (HCV) infection with interferon-α (IFN-α)." | ( Baumert, TF; Berg, T; Buggisch, P; Discher, T; Effenberger, S; Friebe, A; Fromm, G; Heinz, A; Heinze, L; Knop, V; Lieb, K; Link, R; Neumann, K; Ockenga, J; Reimer, J; Rentrop, M; Sarkar, R; Schaefer, M; Schlaepfer, T; Spengler, U; Weidenbach, H; Zeuzem, S, 2012) |
| "Depression is a frequent and potentially disabling sequela of stroke." | ( Aass, HC; Amthor, KF; Lund-Sørensen, N; Ormstad, H; Sandvik, L, 2012) |
| "cruzi-induced depression is independent of active or prior CNS inflammation." | ( de Almeida, LR; de Souza, AS; Lannes-Vieira, J; Moreira, OC; Pereira, IR; Rocha, MS; Silva, AA; Silva, RR; Vilar-Pereira, G, 2012) |
| "Chronic pain and depression are two complex states with sensory/somatic and emotional components, and they may mutually exacerbate one another in conditions of comorbidity, leading to a poorer prognosis." | ( Berrocoso, E; Bravo, L; Leza, JC; Mico, JA; Pérez-Nievas, B; Rey-Brea, R, 2012) |
| "Sleep problems and depression are modifiable host factors that can influence inflammation and impact cancer progression and quality of life." | ( Fiscella, K; Heckler, C; Innominato, PF; Janelsins, M; Kesler, S; Manber, R; Morrow, GR; Mustian, KM; Palesh, OG; Peppone, LJ; Roth, T; Sprod, LK, 2012) |
| "Depression is the most common of all psychiatric disorders and the role of amino acid transmitters in this pathology has been recently studied." | ( Aburto-Arciniega, E; Aguirre-Hernández, R; Cruz-Revilla, C; Guevara-Guzmán, R; Jiménez-Mendoza, A; Mayoral-Mariles, A; Severiano-Pérez, P; Vega-Manriquez, X, 2012) |
| "CM with depression is highly associated with poor cognitive performance and higher likelihood of two or more lesions in MRI (likelihood ratio=6." | ( Chang, CC; Chang, WN; Chen, C; Chen, CH; Chen, NC; Huang, CW; Lin, WC; Lu, CH; Lui, CC; Tsai, NW, 2012) |
| "Depression is a stress-induced disorder and there is compelling evidence for the involvement of hypothalamic-pituitary-adrenal (HPA) axis abnormalities in the disease." | ( Hori, H; Kunugi, H; Numakawa, T; Ota, M, 2012) |
| "Depression is one of the most frequently missed diagnoses in elderly people, with obvious negative effects on quality of life." | ( Berra, B; Corsetto, PA; Faliva, M; Giacosa, A; Montorfano, G; Opizzi, A; Pelucchi, C; Ricevuti, G; Rizzo, AM; Rondanelli, M, 2012) |
| "Depression is a common comorbidity in heart failure and is strongly associated with increased mortality, morbidity, and reduced health status." | ( Fiuzat, M; Jiang, W; Krishnan, R; Kuchibhatla, M; O'Connor, CM; Xiong, GL, 2012) |
| "Depression is a life-threatening psychiatric disorder characterized with a long-term hypercortisolemia in depressed patients." | ( Chang, RC; Lau, BW; Lee, TM; Ma, H; So, KF; Yau, SY; Zhang, E, 2012) |
| "Major depression is a complex multi-factorial disorder with a lifetime diagnosis of nearly 1 out of 6." | ( Choi, D; Huckans, M; Loftis, JM; Manthe, L; Wilhelm, CJ, 2013) |
| "Depression is emerging as an independent cardiovascular disease risk factor." | ( Assisi, AP; Fedullo, F; Gianni, W; Modestino, A; Scuteri, A, 2013) |
| "Major depression is characterized by diverse debilitating symptoms that include hopelessness and anhedonia." | ( Adhikari, A; Andalman, AS; Deisseroth, K; Ferenczi, EA; Finkelstein, J; Gunaydin, LA; Kim, SY; Mirzabekov, JJ; Thompson, KR; Tsai, HC; Tye, KM; Warden, MR; Witten, IB, 2013) |
| "Depression is a common and costly comorbidity in dementia." | ( Baldwin, R; Ballard, C; Banerjee, S; Bentham, P; Burns, A; Dewey, M; Fox, C; Hellier, J; Holmes, C; Katona, C; Knapp, M; Lawton, C; Lindesay, J; Livingston, G; McCrae, N; Moniz-Cook, E; Murray, J; Nurock, S; O'Brien, J; Poppe, M; Romeo, R; Thomas, A; Walwyn, R; Wilson, K, 2013) |
| "Depression is associated with increased HIV transmission risk, increased morbidity, and higher risk of HIV-related death among HIV-infected women." | ( Bangsberg, DR; Clark, G; Dworkin, SL; Hatcher, AM; Hunt, PW; Kumbakumba, E; Martin, JN; Tsai, AC; Weiser, SD, 2012) |
| "Depression is associated with increased risk of coronary heart diseases." | ( Dronjak, S; Jovanovic, P; Spasojevic, N, 2012) |
| "Depression is characterized by sadness, purposelessness, irritability, and impaired body functions." | ( Bose, S; Krishnamohan, R; Mattison, C; Nel, W; Ngu, N; Patel, A; Rais, A; Sandhu, R; Sandhu, S; Shabbir, F; Sharma, S; Sweeney, E, 2013) |
| "The incidence of depression is increasing worldwide." | ( Derom, ML; Martínez-González, MA; Martínez-Ortega, JM; Sayón-Orea, C, 2013) |
| "Indian MSM with depression are at higher odds of engaging in UAS compared to MSM without depression." | ( Anand, VR; Biello, KB; Mayer, KH; Mimiaga, MJ; Safren, SA; Sivasubramanian, M, 2013) |
| "Depression is one of the most common psychiatric diseases." | ( Han, P; Han, T; Peng, W; Wang, XR, 2013) |
| "Major depression is a common psychiatric disorder associated with high symptomatic and functional burdens." | ( Cates, LN; Hedlund, PB; Huitron-Resendiz, S; Roberts, AJ, 2013) |
| "Depression is associated with structural and neurochemical changes in limbic structures, including the hippocampus, that control emotion and mood." | ( Feng, P; Huang, C, 2013) |
| "Depression is associated with a substantial increase in the risk of developing heart failure and is independently associated with increased cardiovascular morbidity and mortality." | ( Bhuiyan, MS; Fukunaga, K; Tagashira, H, 2013) |
| "Depression is common in dementia, causing considerable distress and other negative impacts." | ( Baldwin, R; Ballard, C; Banerjee, S; Bentham, P; Burns, A; Dewey, M; Fox, C; Hellier, J; Holmes, C; Katona, C; Knapp, M; Lawton, C; Lindesay, J; Livingston, G; McCrae, N; Moniz-Cook, E; Murray, J; Nurock, S; O'Brien, J; Orrell, M; Poppe, M; Romeo, R; Thomas, A; Walwyn, R; Wilson, K, 2013) |
| "Geriatric depression is a costly health issue, but little is known about its physiological underpinnings." | ( Dantzer, R; Kelley, KW; Lawson, MA; McCusker, RH; O'Connor, JC; Rodriguez-Zas, SL, 2013) |
| "Depression is a major cause of poor sleep quality and can impede efforts to overcome the chronic fatigue that commonly affects shift nurses." | ( Chang, MY; Chiou, YL; Tseng, CH, 2014) |
| "Depression is among the most common chronic illnesses in the US elderly Medicare population, affecting approximately 11." | ( Kaplan, C; Zhang, Y, 2012) |
| "Depression is a severe mood disorder with increasing morbidity and suicidality, while the current therapy is not satisfactory." | ( Chen, HX; Fan, SY; He, XH; Jin, ZL; Li, YF; Xue, R; Yuan, L; Zhang, LM; Zhang, YP; Zhang, YZ; Zhao, N; Zhong, BH, 2013) |
| "Incidence of depression is significantly higher among HIV positive individuals compared to HIV negative populations." | ( Dashti-Khavidaki, S; Hatamkhani, S; Khalili, H; Khazaeipour, Z; Rezaee, H, 2013) |
| "Postpartum depression is associated with reduced breastfeeding duration." | ( Grewen, K; Meltzer-Brody, S; Stuebe, AM, 2013) |
| "Depression is one of the most burdensome diseases in the world." | ( Sato, K, 2013) |
| "EA treatment for depression is as effective as a recommended dose of fluoxetine." | ( Bao, F; He, W; Ma, C; Sun, H; Wang, DH; Zhang, J; Zhang, YX; Zhao, H, 2013) |
| "Depression is strongly associated with the circadian system, disruption of the circadian system leads to increased propensity to disease and to mood disorders including depression." | ( Angeles-Castellanos, M; Escobar, C; Salgado-Delgado, R; Tapia-Osorio, A, 2013) |
| "Depression is a multicausal disorder and has been associated with the risk to develop cancer, dementia, diabetes, epilepsy and stroke." | ( Borgwardt, S; Lang, UE, 2013) |
| "However, depression is more complex to treat, with physicians reluctant to change prescriptions if patients are responding to a particular antidepressant." | ( Barbui, C; Godman, B; Gustafsson, LL; Miranda, J; Persson, M; Skiöld, P; Wettermark, B, 2013) |
| "Depression is the leading cause of mental disability worldwide." | ( Humphries, D; Rechenberg, K, 2013) |
| "Depression is associated with a lower concentration of zinc in peripheral blood." | ( Goldberger, K; Harimoto, T; Herrmann, N; Lanctôt, KL; Mazereeuw, G; Swardfager, W, 2013) |
| "Depression is a common neuropsychiatric symptom in Parkinson's disease (PD)." | ( Berendse, HW; Foncke, EM; Raijmakers, P; Smit, JH; van den Heuvel, OA; van der Werf, YD; van Dijk, KD; Veltman, DJ; Vriend, C, 2014) |
| "Depression is one of the most frequent neuropsychiatric comorbidities associated with opiate addiction." | ( Dang, W; Du, Y; Jia, W; Liu, R; Shi, J; Wang, J; Wu, B; Zhang, R; Zhou, Q, 2013) |
| "Anxiety and depression are prevalent during pregnancy." | ( Balakrishnan, K; Das, S; Fadzil, A; Japaraj, RP; Malapan, T; Manaf, MR; Midin, M; Nik Jaafar, NR; Razali, R; Sidi, H, 2013) |
| "Depression is one of the most common psychiatric conditions in men." | ( Baharudin, A; Ibrahim, N; Mislan, N; Nik Jaafar, NR; Sidi, H, 2013) |
| "Even though depression is common among men on MMT, it is often missed by the treating doctors." | ( Baharudin, A; Ibrahim, N; Mislan, N; Nik Jaafar, NR; Sidi, H, 2013) |
| "Depression is common among young survivors of sexual abuse." | ( Marimuthu, S; Muhamad, NA; Razali, R; Tan, SM; Wahab, S, 2013) |
| "Clinical depression is a serious mental disorder characterized by low mood, anhedonia, loss of interest in daily activities, and other symptoms, and is associated with severe consequences including suicide and increased risk of cardiovascular events." | ( Duman, RS; Liu, G; Murck, H; Quiroz, J; Sartori, S; Zarate, C, 2013) |
| "Depression is a common condition in patients with epilepsy that entails a deterioration of the quality of life of this population and that, therefore, requires appropriate treatment." | ( Castaño-Monsalve, B, 2013) |
| "Depression is associated with impairments to cognition and brain function at any age, but such impairments in the elderly are particularly problematic because of the additional burden of normal cognitive aging and in some cases, structural brain pathology." | ( Newhouse, PA; Taylor, WD; Zurkovsky, L, 2013) |
| "Major depression is characterized by dysfunction of neuroendocrine and immune networks." | ( Chen, Z; Huang, W; Li, G; Lin, M; Pan, J; Wang, Q; Wu, F; Wu, S; Xie, X; Xu, Y; Yan, Q; Yu, X, 2013) |
| "Depression is a leading cause of disability worldwide." | ( Chan, CH; Chan, CL; Leung, PP; Reddemma, K; Sreevani, R; Wong, V, 2013) |
| "Depression is common among lung cancer patients." | ( Cao, YX; Dong, JC; Du, YJ; Gong, WY; Jin, HL; Li, B; Liu, BJ; Luo, QL; Lv, YB; Shi, SX; Sun, J; Wu, JF; Wu, X; Zhang, HY, 2013) |
| "Depression is a common and debilitating mental illness and is often comorbid with anxiety disorders." | ( Chen, WL; Hu, B; Niu, YY; Tang, XQ; Tian, Y; Xie, B; Xu, KL; Zhang, C; Zhang, P; Zou, W, 2013) |
| "Because depression is associated with significant morbidity and functional disability, it is important to reveal the mechanism of action." | ( Chen, C; Hu, TT; Wei, W; Xu, TJ; Xu, WP; Yang, JM, 2013) |
| "Anxiety and depression are common in diabetics." | ( Agilkaya, S; Aksu, I; Ates, M; Baykara, B; Buyuk, E; Cetinkaya, C; Cingoz, S; Dayi, A; Kiray, M; Sisman, AR; Uysal, N, 2014) |
| "Agitation and depression are among the commonest behavioural and psychological symptoms exhibited by Alzheimer's disease patients." | ( Fuh, JL; Hung, CW; Lirng, JF; Tsai, CF; Wang, SJ, 2013) |
| "Depression is a common non-motor symptom in patients with Parkinson's disease (PD)." | ( Dong, J; Liu, J; Su, Y; Sun, S; Wang, L; Yan, P, 2013) |
| "Pain and depression are frequent co-morbid disorders." | ( Arora, V; Chopra, K, 2013) |
| "Depression is a chronic illness that generally requires lifelong therapy." | ( Chen, Y; Gan, J; Tan, Q; Wang, H; Xue, Y; Zhang, L; Zhang, R; Zhang, Y, 2013) |
| "Depression is associated with poor adherence to medications and worse prognosis in patients with acute coronary syndrome (ACS)." | ( Alcántara, C; Burg, MM; Davidson, KW; Kronish, IM; Rieckmann, N, 2014) |
| "Depression is a common comorbidity in temporal lobe epilepsy (TLE) that is thought to have a neurobiological basis." | ( Cheng, CE; Girard, HM; Iragui, VJ; Kemmotsu, N; Kucukboyaci, NE; McDonald, CR; Tecoma, ES, 2013) |
| "Major depression is one of the most prevalent mental disorders in the population." | ( Lin, YL; Wang, S, 2014) |
| "Depression is a chronic, recurring and potentially life-threatening illness." | ( Doron, R; Einat, N; Kately, N; Lotan, D; Marom, I; Meron, G; Rehavi, M; Winer, A; Yaffe, R, 2014) |
| "Depression is often characterized by attentional biases toward negative items and away from positive items, which likely affects reward and punishment processing." | ( Beevers, CG; Cooper, JA; Denny, T; Gorlick, MA; Maddox, WT; Worthy, DA, 2014) |
| "Depression is a complex neuropsychiatric syndrome that is often very severe and life threatening." | ( Bagga, P; Chakravarty, S; Khandelwal, N; Kumar, A; Maitra, S; Noronha, JM; Patel, AB; Veeraiah, P, 2014) |
| "Depression is a salient emotional feature of chronic pain." | ( D'amour, J; Eberle, SE; Froemke, RC; Goffer, Y; Lee, M; Tukey, D; Wang, J; Xu, D; Ziff, EB, 2013) |
| "Depression is a serious and debilitating psychiatric condition with serious societal health and economic implications." | ( Gobburu, J; Pastoor, D, 2014) |
| "Comorbid depression is commonly observed in individuals who suffer from neuropathic pain, which necessitates improved treatment." | ( Liu, AM; Liu, L; Ma, Q; Wang, C; Xu, Y; Zhang, JF; Zhao, X; Zhou, WH, 2014) |
| "Depression is drug-resistant, if the severity of the symptoms has not decreased to half of the starting situation, despite appropriately conducted treatment with two antidepressants belonging to two different pharmacological categories." | ( Taiminen, T, 2013) |
| "Depression is common in primary care and is associated with marked personal, social and economic morbidity, thus creating significant demands on service providers." | ( Barbui, C; Cipriani, A; Furukawa, TA; Gastaldon, C; Magni, LR; Papola, D; Purgato, M, 2013) |
| "Major depression is a disabling psychiatric illness with complex origins." | ( Hosang, GM; McGuffin, P; Shiles, C; Tansey, KE; Uher, R, 2014) |
| "Hypertension and depression are frequent comorbidities of diabetes." | ( Ahola, AJ; Forsblom, C; Groop, PH; Harjutsalo, V, 2014) |
| "Depression is a proposed risk factor for heart failure based largely on epidemiological data; few experimental data addressing this hypothesis are available." | ( Groban, L; Kitzman, DW; Register, TC; Shively, CA, 2014) |
| "Anxiety, stress and depression are common neuropsychiatric features in diabetic patients." | ( Ekramzadeh, M; Hejazi, N; Mazloom, Z, 2013) |
| "Depression is generally a recurrent psychiatric disorder." | ( Baoying, J; Lei, W; Lingjia, Q; Rui, Z; Wei, L; Xinxing, W, 2014) |
| "Major depression is a complex disorder characterized by genetic and environmental interactions." | ( Chiba, K; Ishibashi, Y; Iwata, K; Izumo, N; Kameyama, T; Karube, Y; Manabe, T; Matsuzaki, H; Morikawa, T; Sasaki, N; Suzuki, B; Terada, K, 2014) |
| "Depression is a serious mental disorder in the world, but the underlying mechanisms remain unclear and the effective cures are scarce." | ( Ding, JH; Geng, F; Hu, G; Lu, M; Yang, JZ, 2014) |
| "Depression is the most important neuropsychiatric complication in chronic kidney disease because it reduces quality of life and increases mortality." | ( Azevedo, VF; Elias, RM; Miranda, CT; Miranda, MP; Teixeira, Mdo C; Teles, F, 2014) |
| "Depression is a common brain disorder affecting about 350 million people worldwide." | ( Coppola, M; Mondola, R, 2014) |
| "Depression is a major psychiatric disorder affecting nearly 21% of the world population and imposes a substantial health burden on society." | ( Chen, X; Du, C; Gu, X; Ke, K; Liu, C; Shen, L; Shi, J; Wang, F; Wu, X; Zhang, CY; Zhou, Y, 2014) |
| "Depression is a common symptom in Parkinson's disease (PD), but its pathophysiology remains unclear." | ( Chen, L; Guo, Y; Hui, YP; Liu, J; Qiao, HF; Wang, Y; Zhang, L; Zhang, QJ, 2014) |
| "Depression is a major public health problem among adults with arthritis and other rheumatic disease." | ( Kelley, GA; Kelley, KS, 2014) |
| "Depression is a common mental disorder." | ( Ke, W; Lihua, P; Su, M; Ziemann-Gimmel, P, 2014) |
| "Stress and depression are associated with neuronal atrophy, characterized by loss of synaptic connections in key cortical and limbic brain regions implicated in depression." | ( Duman, RS, 2014) |
| "Depression is one of the most common mental health disorders and is an emerging public health problem." | ( Kader Maideen, SF; Mukhtar, F; Rampal, L; Sidik, SM, 2014) |
| "Depression is the most widely acknowledged psychological problem among end-stage renal disease (ESRD) patients." | ( Bao, B; Chen, J; Duan, J; Huang, C; Ni, M; Ni, X; Wu, Y; Zhang, J; Zhang, P, 2014) |
| "Although depression is a significant co-morbid condition in chronic illnesses, little is known about the prevalence or risk factors for depressive symptoms in patients with chronic obstructive pulmonary disease (COPD) in India." | ( Das, P; Negi, H; Pandey, K; Raval, AD; Sarkar, M, 2014) |
| "As dementia and depression are co-morbid, we evaluated if this combination would have an effect on cognition." | ( Abraham, R; Nirogi, R; Shinde, A, 2014) |
| "Depression is a major mental health problem during adolescence." | ( Cao, Y; Guo, H; Li, J; Siegrist, J; Yang, W, 2014) |
| "Depression is the most prevalent psychiatric disorder (16." | ( Arias-Carrión, O; Machado, S; Nardi, AE; Pereira, VM; Silva, AC, 2014) |
| "Depression is a common symptom in dementia with Lewy bodies (DLB), Parkinson disease dementia (PDD), and Alzheimer disease (AD), yet its molecular basis remains unclear and current antidepressants do not appear to be effective." | ( Aarsland, D; Alghamdi, A; Ballard, C; Francis, PT; Hortobágyi, T; O'Brien, JT; Thomas, AJ; Vallortigara, J; Whitfield, DR, 2015) |
| "A history of depression is common with hepatitis C but does not affect initiation of antiviral treatment, despite substantially increased risk of psychiatric side-effects." | ( Blunn, A; Chitturi, S; Farrell, G; Kaye, G; Rodrigo, K; Rodriguez-Morales, I; Shadbolt, B; Teoh, N; To, C; Wu, JY, 2014) |
| "Depression is a frequent comorbid disorder in Parkinson's disease and may antedate its motor symptoms." | ( Berghauzen-Maciejewska, K; Dziubina, A; Głowacka, U; Kolasiewicz, W; Kuter, K; Ossowska, K; Wardas, J, 2014) |
| "While depression is frequently managed by general practitioners, often patients self-manage these symptoms with alternative therapies, including St John's wort (SJW)." | ( Carter, M; Densley, K; Forsdike, K; Gunn, J; Pirotta, M, 2014) |
| "Depression is a frequent mood disorder that affects around 33% of stroke patient." | ( Chen, XY; Cheng, SY; Li, J; Wang, RD; Zeng, JW; Zhao, YD, 2014) |
| "Depression is more common in women, occurring at times of hormonal fluctuations as premenstrual depression, postnatal depression and perimenopausal depression." | ( Studd, J, 2015) |
| "Depression is an important cause of decreased quality of life and executive function in patients with advanced cancer." | ( Dai, ZY; Li, DQ; Li, XJ; Yang, WF; Zhen, JP; Zhu, BY, 2014) |
| "Depression is a frequent mood disorder that affects around a third of stroke patients and has been associated with poorer outcomes." | ( Li, YT; Zhang, HJ; Zhao, WL; Zhao, Y, 2014) |
| "Major depression is associated with abnormalities in reward processing at neural and behavioural levels." | ( Browning, M; Cowen, PJ; Mannie, ZN; Williams, C, 2015) |
| "Depression is on the rise globally and expected to lead in global burden of diseases by 2030." | ( Abbas, G; Mahmood, W; Rauf, K, 2015) |
| "Depression is an important factor which affects the management and complications of diabetes." | ( Agarwal, NB; Jha, S; Siddiqui, S; Singh, K; Waghdhare, S, 2014) |
| "Depression is one of the most prevalent mental illnesses, and causes a constant feeling of sadness and lose of interest, which often leads to suicide." | ( Jo, SA; Kim, YH; Leem, YH; Yoon, SS, 2014) |
| "Depression is a major psychiatric illness that is associated with cognitive dysfunctions." | ( Bhagya, V; Raju, TR; Shankaranarayana Rao, BS; Srikumar, BN, 2015) |
| "Depression is common in individuals infected with hepatitis C virus (HCV), and both depression and HCV infection are independently associated with insulin resistance (IR)." | ( Khalili, M; Kornak, J; Shah, SC, 2015) |
| "Also, depression is assessed with special focus on the two key symptoms: depressed mood and anhedonia." | ( Broeren, MA; Kuppens, SM; Meems, M; Nabbe, KC; Oei, SG; Pop, VJ; Truijens, SE; van Son, MJ; Wijnen, HA, 2014) |
| "Both epilepsy and depression are characterized by a high incidence of pharmacoresistance, which might be based on overactivity of multidrug transporters like P-glycoprotein at the blood-brain barrier." | ( Bankstahl, JP; Bankstahl, M; Klein, S; Löscher, W, 2015) |
| "Depression is a debilitating condition with a profound impact on quality of life for millions of people worldwide." | ( Agudelo, LZ; Barres, R; Bhat, M; Correia, JC; Erhardt, S; Femenía, T; Ferreira, DMS; Goiny, M; Izadi, M; Krook, A; Lindskog, M; Martinez-Redondo, V; Orhan, F; Pettersson, AT; Porsmyr-Palmertz, M; Ruas, JL; Schuppe-Koistinen, I; Zierath, JR, 2014) |
| "Depression is a neuropsychiatric disorder that is commonly found in patients with Parkinson's disease (PD)." | ( Dal Pont, GC; Luciano, TF; Paganini, CS; Pinho, RA; Pozzi, BG; Quevedo, J; Souza, CT; Souza, PS; Tuon, T; Valvassori, SS, 2014) |
| "Depression is associated with elevated kynurenine levels, a tryptophan metabolite generated under stress and inflammatory conditions." | ( Moon, HY; van Praag, H, 2014) |
| "Depression is common in patients with cardiometabolic diseases but little is known about the relationship, if any, between cardiovascular risk factor values and depressive symptoms in patients with these conditions." | ( Barry, SJ; Cavanagh, J; Der, G; Jani, BD; Mair, FS; Sattar, N, 2014) |
| "Depression is the leading psychiatric disorder with a high risk of morbidity and mortality." | ( Krakowska, A; Mlyniec, K; Nowak, G; Opoka, W; Ostachowicz, B; Reczynski, W, 2014) |
| "Risk for depression is expressed across multiple levels of analysis." | ( Badanes, LS; Dozois, DJ; Hankin, BL; Hayden, EP; Jordan, PL; Mackrell, SV; Olino, TM; Sheikh, HI; Singh, SM, 2014) |
| "Depression is a common psychiatric disorder associated with chronic stress." | ( Cao, WY; Dai, RP; Duan, J; Hu, ZL; Li, CQ; Li, F; Luo, YW; Wang, XQ; Xu, Y; Zhang, JY; Zhong, XL; Zhou, M, 2015) |
| "Depression is an inflammatory, commonly occurring and lethal psychiatric disorder having high lifetime prevalence." | ( Baruah, CC; Dwivedi, S; Hazarika, NK; Jangra, A; Kumar, P; Lahkar, M; Sulakhiya, K, 2014) |
| "Among them, depression is a common psychiatric symptom, and links to poorer recovery." | ( Chen, Y; Duanmu, W; Feng, H; Fu, C; Ge, H; Hu, R; Liu, X; Sui, J; Tan, L; Tang, J, 2015) |
| "Depression is known to be related to an increased risk of cardial morbidity and mortality, although the risk architecture is not completely understood." | ( Deuschle, M; Gilles, M; Hartmann, MF; Kommer, M; Lederbogen, F; Marzina, A; Meyer-Lindenberg, A; Michaely, H; Scharnholz, B; Wudy, SA, 2014) |
| "Depression is a common and important cause of morbidity, and results in a significant economic burden." | ( Boyko, M; Brotfain, E; Grinshpun, J; Gruenbaum, BF; Gruenbaum, SE; Kutz, R; Shapira, Y; Zlotnik, A; Zvenigorodsky, V, 2015) |
| "Depression is common in women, especially during pregnancy and the postpartum period." | ( Andrade, C, 2014) |
| "Depression is one of the mental disorders with a state of low mood and aversion to activities that exerts a negative effect on a person's thoughts and behaviour." | ( Joshi, S; Koch, B; Roy, M; Tapadia, MG, 2014) |
| "Depression is one of the most prevalent challenges of mental conditions." | ( Barati, M; Farajdokht, F; Mehrpouya, S; Nahavandi, A; Soleimani, M, 2015) |
| "Depression is associated with receipt of higher doses of prescription opioids." | ( Burge, S; Lustman, PJ; Salas, J; Scherrer, JF; Schneider, FD, 2015) |
| "Depression is a complex psychiatric disorder, and its etiology and pathophysiology are not completely understood." | ( Ge, L; Shen, J; Tian, HF; Wang, F; Wu, CF; Yang, JY; Zhang, JH; Zhang, R; Zhu, MM, 2015) |
| "Depression is recognised as an independent cardiovascular risk factor in adults." | ( Allen, NB; Bei, B; Byrne, ML; Murray, G; Nicholas, CL; Raniti, M; Trinder, J; Waloszek, JM; Woods, MJ, 2015) |
| "Pain and depression are each prevalent among opioid dependent patients receiving maintenance buprenorphine, but their interaction has not been studied in primary care patients." | ( Anderson, BJ; Bailey, GL; Herman, DS; Stein, MD; Straus, J; Uebelacker, LA; Weisberg, RB, 2015) |
| "Depression is one of the most commonly encountered psychiatric problems in peritoneal dialysis (PD) patients." | ( Bek, S; Dervisoglu, E; Eraldemir, FC; Kir, H; Ozsoy, D, 2015) |
| "Since depression is associated with a dysfunction of the adenosinergic system, we investigated the involvement of adenosine A1 and A2A receptors in the antidepressant-like effect of creatine in the TST." | ( Cunha, MP; Kaster, MP; Oliveira, Á; Pazini, FL; Ramos-Hryb, AB; Rodrigues, AL; Rosa, JM, 2015) |
| "Major depression is diagnosed in 18% of patients following myocardial infarction (MI), and the antidepressant fluoxetine is shown to effectively decrease depressive symptoms and improve coronary heart disease prognosis." | ( Chen, J; Chen, Y; Hu, D; Liang, J; Qu, C; Shi, S; Wang, F; Yang, B; Yuan, X, 2015) |
| "Human depression is a major burden, both on the individuals who suffer from the disease and on society at large." | ( Hanssen, JF; Hestad, KA; Rudi, K; Szczesniak, O, 2016) |
| "Depression is highly prevalent in patients with schizophrenia and is associated with significant clinical consequences, but there is no known biomarker for depression in schizophrenia." | ( Chiappelli, J; Gaston, F; Hong, LE; Kochunov, P; McMahon, RP; Muellerklein, F; Rowland, LM; Tagamets, M; Wijtenburg, SA, 2015) |
| "Depression is a predictor of poor prognosis in patients with heart failure." | ( De Gobbi, JI; Matsubara, BB; Matsubara, LS; Omoto, AC; Roscani, MG; Siqueira, TF, 2015) |
| "Depression is a major psychiatric disorder affecting more than 120 million people worldwide every year." | ( Celikel, T; Freudenberg, F; Reif, A, 2015) |
| "Because depression is associated with poor HF outcomes, the present study tested the hypothesis that depression is associated with a dysregulated NO pathway in patients with HF." | ( Eisel, UL; Garrelds, IM; Kop, WJ; Mommersteeg, PM; Schalkwijk, CG; Schoemaker, RG, 2015) |
| "Depression is considered to be an independent cardiovascular risk factor and it may worsen the symptoms of already established cardiovascular pathology such as coronary heart disease, chronic heart failure, stroke and hypertension." | ( Napalkov, DA; Nuralieva, NF, 2014) |
| "Major depression is common in older adults and associated with greater health care utilisation and increased risk of poor health outcomes." | ( Cockayne, N; Duffy, SL; Hermens, DF; Hickie, IB; Lagopoulos, J; Naismith, SL, 2015) |
| "Paediatric depression is estimated to affect 15-20% of youths prior to adulthood and is associated with significant social, educational and physical impairment." | ( Lopresti, AL, 2015) |
| "Depression is a frequent comorbid condition in patients with Alzheimer's disease (AD)." | ( Hoshino, R; Inoue, J; Ishida, W; Nojima, H; Okamoto, N, 2016) |
| "Depression is a frequent comorbidity in HIV infection that has been associated with worse treatment outcomes and increased mortality." | ( Cassol, E; Gabuzda, D; Kirk, GD; Mehta, SH; Misra, V; Morgello, S, 2015) |
| "Depression is also more common in women and is associated with poor QoL and early mortality than men." | ( Bhatt, P; Mehta, JL; Parikh, K; Parikh, P; Parikh, R; Patel, A, 2015) |
| "Depression is a debilitating complication of brucellosis and how best to treat this is a matter of debate." | ( Akhondzadeh, S; Ashrafizadeh, SG; Entezari, P; Jafari, S; Rasoulinejad, M; Seddighi, S; Zeinoddini, A, 2015) |
| "Chronic pain and depression are two complex states that often coexist in the clinical setting and traditional antidepressants and analgesics have shown limited clinical efficacy." | ( Brüning, CA; Duarte, MM; Gai, BM; Martini, F; Nogueira, CW; Sampaio, TB; Soares, SM, 2015) |
| "Late-life depression is associated with high rates of morbidity, premature mortality, disability, functional decline, caregiver burden and increased health care costs." | ( Amminger, PG; Bonomally, R; Christensen, HM; Cockayne, NL; Duffy, SL; English, A; Hickie, IB; Mackinnon, A; Naismith, SL, 2015) |
| "Depression is a serious illness that affects millions of patients." | ( Bertekap, R; Bronson, JJ; Cunningham, MA; Davis, CD; Degnan, AP; Gillman, KW; Han, Y; Hu, J; Krause, K; Krause, R; Li, YW; Lodge, NJ; Macor, JE; Mattson, G; Morgan, D; Rajamani, R; Taber, MT; Taylor, SJ; Tora, GO, 2015) |
| "Depression is a well-known complication of breast cancer, which is known to adversely affect quality of life, prognosis, and survival in breast cancer patients." | ( Akhondzadeh, S; Arya, P; Emami, SA; Esfandbod, M; Kashani, L; Kaviani, A; Mohammadinejad, P; Najafi, M; Zeinoddini, A, 2015) |
| "Depression is the leading cause of disability for childbearing women." | ( Brown, H; Sanghera, R; Wong, ST, 2015) |
| "Depression is a highly prevalent and severely disabling condition globally." | ( Bhad, R; Hazari, N, 2015) |
| "Major depression is known to be associated with cardiovascular abnormalities, and oxidative stress has been suggested to play a role." | ( Aalkjaer, C; Bouzinova, EV; Kravtsova, VV; Matchkov, VV; Wiborg, O, 2015) |
| "Animal models of depression are efficient in detecting effective treatments but have done little to increase the reach of antidepressant drugs." | ( Belzung, C; Willner, P, 2015) |
| "Anxiety and depression are common in Parkinson's disease (PD) patients, yet their prevalence and severity compared to individuals without PD requires more research." | ( Fareez, F; Qureshi, AR; Rana, AQ; Rana, MA, 2016) |
| "Depression is common among hemodialysis patients." | ( Donia, AF; Elassy, M; Elbahaey, W; Zaki, NF, 2015) |
| "Depression is common among our Egyptian hemodialysis patients." | ( Donia, AF; Elassy, M; Elbahaey, W; Zaki, NF, 2015) |
| "Depression is a common co-morbid condition most often observed in subjects with mild cognitive impairment (MCI) and during the early stages of Alzheimer's disease (AD)." | ( Franklin, A; Miguelez, C; Raskind, MA; Sikkema, C; Szot, P; Ugedo, L; Vidaurrazaga, I; Wang, Y; Wilkinson, CW, 2016) |
| "Depression is highly prevalent in COPD patients, and both diseases are believed to be associated with inflammation." | ( Czajkowska-Malinowska, M; Kędziora, J; Kędziora-Kornatowska, K; Korte, SM; Rybka, J; Wiese, M, 2016) |
| "Depression is a serious psychological disorder that causes extreme economic loss and social problems." | ( Chen, WC; Chou, ML; Hao, CW; Lai, YS; Lin, SH; Lu, KH; Sheen, LY, 2015) |
| "Depression is a serious psychiatric illness that affects millions of people worldwide." | ( Mlyniec, K, 2015) |
| "For 2 years, a depression care manager worked with primary care physicians to provide algorithm-based care for depression, offering psychotherapy, increasing the antidepressant dose if indicated, and monitoring symptoms, medication adverse effects, and treatment adherence." | ( Bogner, HR; Bruce, ML; Gallo, JJ; Hwang, S; Joo, JH; Morales, KH; Reynolds, CF, 2016) |
| "Depression is the most common mental disorder and involves many factors." | ( Dehghani, A; Mozaffari-Khosravi, H; Rajizadeh, A; Yassini-Ardakani, M, 2016) |
| "Depression is a common worldwide mental disorder whose etiology remains unclear; there is also a lack of effective therapeutic agents." | ( Hu, XY; Jiang, XH; Liu, D; Qiu, HM; Yang, JX; Zhou, QX, 2015) |
| "Depression is a common mental illness and a leading cause of disability." | ( Blakely, RD; McMeekin, AM; Moussa-Tooks, AB; Nackenoff, AG; Veenstra-VanderWeele, J, 2016) |
| "Depression is one of the major health problems of our world." | ( Ahmadian-Attari, MM; Kamalinejad, M; Khoshdel, A; Noorbala, AA; Taghva, A, 2017) |
| "Late life depression is burdensome, and common in LMIC." | ( Acosta, D; Ferri, CP; Gallardo, S; Guerra, M; Huang, Y; Jacob, KS; Jimenez-Velazquez, IZ; Liu, Z; Llibre Rodriguez, JJ; Prina, AM; Prince, M; Salas, A; Sosa, AL; Uwakwe, R; Williams, JD, 2016) |
| "Depression is associated with alterations in corticostriatal reward circuitry." | ( Felger, JC; Haroon, E; Hu, X; Jung, MY; Li, Z; Miller, AH; Woolwine, BJ, 2016) |
| "Major depression is a multifactorial disease, involving both environmental and genetic risk factors." | ( Balsevich, G; Chen, A; Dournes, C; Hartmann, J; Holsboer, F; Labermaier, C; Masana, M; Müller, MB; Santarelli, S; Schmidt, MV; Uribe, A; Wagner, KV, 2016) |
| "Depression is one of the major causes of disability worldwide, but the complete etiology of depression is not fully understood." | ( Carvalho, LA; de Oliveira, C; Souza-Teodoro, LH; Walters, K, 2016) |
| "Depression is considered a syndrome with a constellation of symptoms that are frequently categorized into 3 domains including affective, somatic and cognitive." | ( Broen, MP; Köhler, S; Kuijf, ML; Leentjens, AF; McDonald, WM; Richard, IH, 2016) |
| "Depression is a major global public health concern." | ( Kauhanen, J; Lehto, SM; Ruusunen, A; Tolmunen, T; Tuomainen, TP; Voutilainen, S; Yary, T, 2016) |
| "Depression is increasingly become a global public healthy problem." | ( Fang, XY; Hu, CY; Jin, SL; Li, YC; Ma, LG; Pei, YY; Shen, JD, 2016) |
| "Depression is associated with hypothalamic-pituitary-adrenal (HPA) axis hyperactivity and testosterone exerts suppressive effects on the HPA axis." | ( Chow, C; Galea, LA; Hamson, DK; Lieblich, SE; Tehrani, A; Wainwright, SR; Workman, JL, 2016) |
| "Depression is one of the most common neuropsychiatric disorders and has been associated with oxidative stress and brain protein alterations." | ( Bai, X; Bo, S; Li, T; Liu, D; Liu, H; liu, S; Wang, X; Wang, Z; Wu, L; Xie, Y, 2016) |
| "Depression is highly prevalent in diabetes (DM)." | ( Balogh, D; Fekete, A; Hodrea, J; Hosszu, A; Koszegi, S; Lenart, L; Szabo, AJ; Szkibinszkij, E; Vannay, A; Veres-Szekely, A; Wagner, L; Zelena, D, 2016) |
| "Depression is a major mood disorder affecting people worldwide." | ( Liu, Y; Pan, B, 2015) |
| "People with depression are usually managed in primary care and antidepressants are often the first-line treatment, but only one third of patients respond fully to a single antidepressant." | ( Anderson, IM; Campbell, J; Chew-Graham, C; Davies, S; Dickens, C; Gilbody, S; Hollingworth, W; Kessler, D; Lewis, G; Macleod, U; Peters, TJ; Tallon, D; Wiles, N, 2016) |
| "Major depression is a chronic and debilitating illness that effects approximately 1 in 5 people, but currently available treatments are limited by low rates of efficacy, therapeutic time lag, and undesirable side effects." | ( Duman, RS; Gerhard, DM; Wohleb, ES, 2016) |
| "Childhood depression is often chronic and recurrent, with only modest improvements after optimal treatments." | ( Bernstein, I; Emslie, G; Isa, A; Kennard, B; Mayes, T; Trivedi, M, 2017) |
| "Depression is associated with increased levels of pro-inflammatory cytokines." | ( Khanam, R; Thomas, J; Vohora, D, 2016) |
| "Depression is a kind of mood disorder." | ( Amagasu, N; Ishida, T; Kawanoguchi, J; Mizuno, K; Takagi, K; Tanahashi, N; Wang, G; Yi, G, 2016) |
| "Prenatal depression is associated with adverse offspring outcomes, and the prevailing mechanistic theory to account for mood-associated effects implicates alterations of the maternal and foetal hypothalamic-pituitary adrenal (HPA) axes." | ( Braithwaite, EC; Murphy, SE; Ramchandani, PG, 2016) |
| "Depression is also defined as an inflammatory disorder." | ( Donma, MM; Donma, O, 2016) |
| "Depression is a severe and chronic psychiatric disease, affecting 350 million subjects worldwide." | ( Dong, C; Hammock, BD; Han, M; Hashimoto, K; Ishima, T; Ma, M; Morisseau, C; Ren, Q; Wagner, KM; Yang, C; Yang, J; Yao, W; Zhang, JC, 2016) |
| "Depression is a common psychopathological disorders." | ( Ding, Q; Huang, J; Li, H; Mo, F; Shen, H; Shen, Z; Tian, X; Wang, X, 2016) |
| "Depression is associated with impairments in higher-order cognitive functions and information processing, which persist independently of clinical symptom change with treatment." | ( Etkin, A; Gyurak, A; Harris, A; Shilyansky, C; Usherwood, T; Williams, LM, 2016) |
| "Parental depression is a significant risk factor for adolescents' engagement in risk taking." | ( Fuligni, AJ; Galván, A; Lieberman, MD; Qu, Y; Telzer, EH, 2016) |
| "Although depression is the leading cause of disability worldwide, its pathophysiology is poorly understood." | ( Abe-Higuchi, N; Hara, K; Higuchi, F; Hobara, T; Kobayashi, A; Uchida, S; Watanabe, Y; Yamagata, H, 2016) |
| "Objectives Depression is tightly associated with cardiovascular comorbidity and accounts for high financial and social burden worldwide." | ( Amiri, S; Anoush, M; Bergen, H; Haj-Mirzaian, A; Hosseini, MJ; Jafarian, I; Rahimi-Balaei, M; Sonei, N, 2017) |
| "Depression is a major neuropsychiatric disorder that exerts deleterious effects upon public health." | ( Cheng, Z; Fan, C; Gao, R; Liu, Z; Qi, Y; Yu, SY; Zhu, X, 2016) |
| "Depression is a common psychiatric disorder that affects millions of people around the world, however, little is known about the pathophysiology of depression and the therapeutic strategy for anti-depression." | ( Pan, J; Wang, S, 2016) |
| "Major depression is a common long-lasting or recurrent psychiatric disease with high lifetime prevalence and high incidence of suicide." | ( Chen, C; Chen, G; Chen, Y; Dong, Y; Duan, J; Su, Q; Tao, W; Wang, H; Xia, B; Xue, W, 2016) |
| "Depression is a common symptom in Parkinson's disease (PD); however, its pathophysiology is unclear." | ( Du, CX; Han, LN; Liu, J; Sun, YN; Wang, T; Zhang, J; Zhang, L; Zhang, YM, 2016) |
| "Major depression is one of the most prevalent psychiatry comorbidities of alcohol use disorders (AUD)." | ( Aguiar, FS; Choi, DS; Hinton, DJ; Ho, AM; Jia, YF; Karpyak, VM; Qiu, Y; Weinshilboum, RM, 2016) |
| "Depression is a major comorbidity factor of diabetes and the outcome of one disorder influences the other." | ( Bharne, AP; Kokare, DM; Nakhate, KT; Subhedar, NK; Yedke, SU, 2016) |
| "Depression is a highly prevalent disease with a high morbidity and mortality risk." | ( Dagnelie, PC; Denollet, J; Henry, RM; Koster, A; Pouwer, F; Schalkwijk, CG; Schaper, NC; Schram, MT; Sep, SJ; Stehouwer, CD; van der Kallen, CJ; van Dooren, FE; Verhey, FR, 2017) |
| "Depression is a heterogeneous disorder characterized by alterations at psychological, behavioural, physiological, neurophysiological, and neurochemical levels." | ( Ahnaou, A; Drinkenburg, WH, 2016) |
| "Depression is a significant public health issue across all sociodemographic groups and is identified as a common and serious mental health problem particularly among the older adult population." | ( Abdin, E; Chong, SA; Chua, BY; Magadi, H; Mahendran, R; Pang, S; Picco, L; Sambasivam, R; Seow, E; Subramaniam, M; Vaingankar, JA, 2016) |
| "Depression is considered as one of the most prevalent health ailments." | ( Dhawan, DK; Kaur, A; Singla, N, 2016) |
| "Depression is associated with high CRP levels and low FeNO levels." | ( Cepeda, MS; Makadia, R; Stang, P, 2016) |
| "Depression is frequent in patients with heart failure and is associated with adverse clinical outcomes." | ( Angermann, CE; Blankenberg, S; Böhm, M; Deckert, J; Edelmann, F; Ertl, G; Faller, H; Gelbrich, G; Gottwik, M; Graf, T; Gunold, H; Haass, M; Kindermann, I; Pankuweit, S; Prettin, C; Schunkert, H; Störk, S; Wachter, R, 2016) |
| "Considering that depression is involved in monoamine reduction, this study evaluated the antidepressant-like effects of gypenosides in mice exposed to chronic unpredictable mild stress (CUMS)." | ( Chen, SM; Chen, XM; Fang, XY; Li, CF; Li, YC; Liu, Q; Mu, RH; Wang, SS; Yi, LT, 2016) |
| "Maternal depression is an important public health concern." | ( Dutt, V; Haldar, K; Kumar, P; Pereira, SK; Powell-Jackson, T; Tougher, S, 2016) |
| "Depression is known to occur frequently in chronic hepatitis C viral (HCV) patients receiving interferon (IFN)-α therapy." | ( Fujigaki, H; Imamura, Y; Ishibashi, T; Kim, HC; Kubo, H; Mamiya, T; Mitani, S; Murakami, Y; Nabeshima, T; Nishikawa, M; Ohta, Y; Saito, K; Takahashi, Y; Takakura, Y; Tashiro, T; Tomita, E; Watcharanurak, K; Yamamoto, Y, 2016) |
| "Depression is a serious mental disorder that is becoming more common." | ( Altvater, EET; Antunes, MS; Boeira, SP; de Oliveira Espinosa, D; Donato, F; Giacomeli, R; Gomes, NS; Jesse, CR; Ruff, JR, 2016) |
| "Depression is a significant public health concern all over the world, especially in modern communities." | ( Ahmed, SM; Ali, SS; Ayuob, NN; El Wahab, MGA; Suliaman, M, 2016) |
| "We demonstrate that depression is associated with decreased gut microbiota richness and diversity." | ( Beers, S; Borre, Y; Clarke, G; Cryan, JF; Deane, J; Dinan, TG; El Aidy, S; Fitzgerald, P; Hoban, AE; Kelly, JR; Kennedy, PJ; Moloney, G; O' Brien, C; Patterson, E; Ross, P; Scott, K; Scott, L; Stanton, C, 2016) |
| "Major depression is a life threatening neuropsychiatric disorder that produces mental illness and major cause of morbidity." | ( Kumar, S; Mondal, AC, 2016) |
| "Depression is a recurring and life-threatening illness that affects up to 120 million people worldwide." | ( Armenta, K; Call, T; Ferguson, D; Hesterman, J; Keeley, E; Kim, HD; Kronman, H; Magazu, S; Nestler, EJ; Neve, RL, 2016) |
| "Apathy and depression are closely related to the prefrontal area in AD, and they may affect the relationship between positive affect and the left prefrontal area." | ( Hayashi, S; Ishihara, T; Miki, T; Oshima, E; Sato, S; Terada, S; Yamada, N; Yokota, O, 2016) |
| "Depression is a recurrent illness with high rates of chronicity, treatment-resistance and significant economic impact." | ( Amari, E; Dougall, D; Galizia, I; Jones, TN; Lam, RW; Macritchie, K; Massei, GJ; Oldani, L; Yatham, LN; Young, AH, 2016) |
| "Depression is a major health problem in which oxidative stress and inflammation are inextricably connected in its pathophysiology." | ( Abuelezz, SA; Hendawy, N; Magdy, Y, 2017) |
| "Depression is an important post-stroke sequela with negative impact on mortality, functional outcome and quality of life." | ( Yang, Y; Zhang, XF; Zou, W, 2016) |
| "Geriatric depression is one of the most common psychiatric disorders in later life." | ( Ciliberto, M; De Crescenzo, F; Ebmeier, KP; Janiri, L; Menghini, D; Treglia, G, 2017) |
| "Depression is often comorbid with alcohol misuse, so relations of AUD with reward deprivation might be due in part to the presence of depressive symptoms in young adults." | ( Dennhardt, AA; Joyner, KJ; Martens, MP; Murphy, JG; Pickover, AM; Soltis, KE, 2016) |
| "Depression is one of the leading causes of disease-related disability in women, and they are nearly twice as likely as men to suffer from an episode of depression." | ( Sassarini, DJ, 2016) |
| "Depression is a neuropsychiatric disorder accompanied by a decrease in the brain-derived neurotrophic factor (BDNF) signalling cascade in the hippocampus." | ( Huang, C; Jiang, B; Song, L; Wang, H; Wang, YJ; Wu, F; Zhang, W; Zhu, Q, 2017) |
| "Depression is characterized by excessive VS coupling to cognitive control and associative networks during losses versus rewards." | ( Diwadkar, V; Kodavaganti, S; Ng, R; Phillips, M; Quevedo, K; Scott, H; Smyda, G, 2017) |
| "Also, depression is common in adults with type 2 diabetes mellitus (T2DM)." | ( Chen, JS; He, JL; Liu, X; Nie, H; Qiu, ZK; Shen, YG; Zeng, J; Zhang, GH, 2016) |
| "Anxiety and depression are more common among females and those experiencing diabetes and menopause." | ( Ahmed, SI; Clavarino, AM; Hasan, SS; Kairuz, T; Mamun, AA; Thiruchelvam, K, 2016) |
| "Depression is a common disease that afflicts one in six people at some points in life." | ( Chen, Z; Gong, Y; Hu, W; Huang, C; Wang, P; Yang, R; Zhang, W, 2017) |
| "Depression is one of the major psychiatric comorbidities having a major impact on the quality of life in people with epilepsy (PWE)." | ( Goel, RK; Singh, T, 2017) |
| "Arthritis and depression are two of the top disabling conditions." | ( Sambamoorthi, U; Shah, D; Zhao, X, 2017) |
| "Depression is the most common form of mental disability in the world." | ( Freiman, SV; Gulyaeva, NV; Lazareva, NA; Levchenko, OA; Levshina, IP; Novikova, MR; Onufriev, MV; Stepanichev, MY; Tishkina, AO, 2016) |
| "Depression is a mental disorder characterized by a pervasive low mood and loss of pleasure or interest in usual activities, and often results in cognitive dysfunction." | ( Guo, J; Guo, R; Wang, C, 2017) |
| "Anxiety and depression are the most frequent comorbidities of different types of convulsive and non-convulsive epilepsies." | ( Fedotova, IB; Kostina, ZA; Nikolaev, GM; Perepelkina, OV; Poletaeva, II; Sarkisova, KY; Surina, NM, 2017) |
| "Juvenile depression is of great concern with only limited treatment currently approved." | ( Brink, CB; Harvey, BH; Schoeman, JC; Steyn, SF, 2017) |
| "Anxiety and depression are common in Alzheimer's disease (AD)." | ( Ansari, F; Khalili, M; Kiasalari, Z; Rahmati, B; Roghani, M, 2017) |
| "Considering that depression is an inflammatory related mental disease, our present study was aimed to investigate the role of ferulic acid in the regulation of microglia activation, pro-inflammatory cytokines, nuclear factor kappa B (NF-κB) and nucleotide binding and oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome in mice exposed to chronic unpredictable mild stress (CUMS)." | ( Li, HB; Li, YC; Liu, YM; Shen, JD; Xu, LP; Yi, LT, 2017) |
| "Perinatal depression is highly prevalent in South Asia." | ( Ahmad, I; Atif, N; Fuhr, DC; Krishna, RN; Lazarus, A; Nisar, A; Patel, V; Rahman, A; Raman, R; Sikander, S, 2017) |
| "Depression is a major public health challenge worldwide, and polyunsaturated fatty acids (PUFAs), especially n-3 PUFAs, have been found to inversely associate with the risk of depression." | ( Kauhanen, J; Lehto, SM; Nurmi, T; Ruusunen, A; Tolmunen, T; Tuomainen, TP; Voutilainen, S; Yary, T, 2017) |
| "Depression is a serious mental illness." | ( Depciuch, J; Doboszewska, U; Nowak, G; Parlinska-Wojtan, M; Sowa-Kućma, M; Szewczyk, B, 2017) |
| "Depression is the most common psychiatric disorder among cancer patients." | ( He, C; Huang, T; Hui, L; Pan, Y; Wei, Y; Zhou, F, 2017) |
| "Chronic stress and depression are challenging conditions to treat, owing to their complexity and lack of clinically available and effective therapeutic agents." | ( Liu, H; Sun, Y; Zhang, C; Zhu, X, 2017) |
| "Depression is a common and disabling complication of traumatic brain injury (TBI)." | ( Acion, L; Jones, M; Jorge, RE, 2017) |
| "Anxious depression is a prevalent disease with devastating consequences and a poor prognosis." | ( Castilla-Ortega, E; Chun, J; Estivill-Torrús, G; García-Fernández, MI; Moreno-Fernández, RD; Pedraza, C; Pérez-Martín, M; Rodríguez de Fonseca, F; Rosell Del Valle, C; Santín, LJ, 2017) |
| "Maternal depression is a major public health problem in low- and middle-income countries including India." | ( Phalke, V; Shidhaye, P; Shidhaye, R, 2017) |
| "Late-life depression is often associated with cognitive impairments and disability, which may persist even after adequate antidepressant drug treatment." | ( Amore, M; Belvederi Murri, M; Bertolotti, M; Ceresini, G; Cremonini, A; Ferrari, S; Menchetti, M; Mussi, C; Neri, G; Neri, M; Neviani, F; Simoncini, E; Squatrito, S; Toni, G; Triolo, F; Tripi, F; Zanetidou, S, 2017) |
| "Depression is a common mental disorder affecting around 350 million people worldwide." | ( Kondo, M; Koyama, Y; Nakamura, Y; Shimada, S, 2018) |
| "It is known that depression is a psychiatric disorder with a high prevalence worldwide, including high rates among adolescents." | ( Arcego, DM; Berlitz, C; Dalmaz, C; do Couto Nicola, F; Dos Santos Garcia, E; Gaelzer, MM; Hoppe, JB; Klein, CP; Krolow, R; Lampert, C; Lazzaretti, C; Toniazzo, AP, 2018) |
| "Depression is a chronic, recurring and potentially life-threatening illness." | ( Huang, M; Lu, X; Wang, Y; Wei, R; Xu, J, 2017) |
| "Depression is a common mental disorder and a leading cause of disability." | ( Chen, Z; Li, Z; Zhang, H; Zhong, Z; Zhou, Z, 2017) |
| "Depression is extremely harmful to modern society." | ( Aquino, NS; Oliveira, VEM; Pádua-Reis, M; Pereira, GS; Prado, MAM; Prado, VF; Szawka, RE, 2017) |
| "Depression is hypothesized to be causally associated with an imbalance in the kynurenine pathway, with an increased metabolism down the 3-hydroxykynurenine (3HK) branch of the pathway leading to increased levels of the neurotoxic metabolite, quinolinic acid (QA), which is a putative N-methyl-d-aspartate (NMDA) receptor agonist." | ( Bliss, SA; Dantzer, R; Drevets, WC; Ford, BN; McMillin, JR; Morris, HM; Savitz, JB; Suzuki, H; Teague, TK; Wurfel, BE, 2017) |
| "Depression is a potential marker of preclinical Alzheimer's disease (AD)." | ( Barker, PB; Cheng, J; Gao, X; Han, Y; Jing, B; Li, Y; Liu, H; Mu, B; Wang, H; Yu, H, 2017) |
| "Depression is a prevalent psychiatric disorder with an increasing impact in global public health." | ( Alves, ND; Bessa, JM; Correia, JS; Machado-Santos, AR; Mateus-Pinheiro, A; Morais, M; Patrício, P; Pereira, J; Pinto, L; Sousa, N, 2017) |
| "Obesity and depression are among the most pressing health problems in the contemporary world." | ( Chaves Filho, AJM; de Lucena, DF; Lima, CNC; Macedo, D; Maes, M; Vasconcelos, SMM, 2018) |
| "Depression is a polygenic and highly complex psychiatric disorder that remains a major burden on society." | ( Gergues, MM; Samuels, BA; Yohn, CN, 2017) |
| "Depression is a recurrent neuropsychiatric disorder that affects millions of individuals worldwide and impact negatively on the patients' social functions and quality of life." | ( Adebesin, A; Adeoluwa, OA; Eduviere, AT; Umukoro, S, 2017) |
| "Treatment-resistant depression is a major health problem worldwide." | ( Haleem, DJ; Ikram, H, 2017) |
| "Depression is a recurrent and disabling psychiatric illness and current evidences support that oxidative stress and neuroinflammation are mechanisms underlying the pathophysiology of this psychiatric condition." | ( Begnini, K; Casaril, AM; Collares, T; Domingues, M; Fronza, M; Lenardão, EJ; Nogueira, CW; Savegnago, L; Seixas, FK; Vieira, B, 2017) |
| "Major depression is one of the most common affective disorders caused by schizophrenia." | ( Briones-Aranda, A; Espinosa-Raya, J; Picazo, O; Suárez-Santiago, JE, 2017) |
| "Depression is associated with poor post-ACS prognosis; however, few investigations have focused on younger patients." | ( Burg, MM; Frazier, L; Padhye, NS; Sanner, JE; Yammine, L, 2017) |
| "Depression is a common mental disorder characterized by the mood of deep sadness." | ( Buran, İ; Elyas, H; Etem, EÖ; Tektemur, A, 2017) |
| "Depression is one of the most frequent psychiatric disorders of Alzheimer's disease (AD)." | ( Cui, L; Hattori, S; Hayashi, T; Ikejima, T; Liu, B; Liu, W; Song, X; Tashiro, SI; Ushiki-Kaku, Y; Xu, F; Zhou, B, 2017) |
| "Stress and depression are common in textile industry employees due to inadequate working conditions and challenging socioeconomic conditions." | ( Gnanaselvam, NA; Joseph, B, 2018) |
| "Depression is one of the most common chronic mental illnesses globally and in India." | ( Anjana, RM; Mohan, V; Poongothai, S; Radha, S; Shanthi Rani, CS; Sundari, BB, 2017) |
| "Depression is a disorder with a high incidence that has been increasing worldwide although the pathophysiology remains unclear." | ( Camargo, A; Dalmagro, AP; Zeni, ALB, 2017) |
| "Depression is one of the important world-wide health problems." | ( Ali, S; Ayuob, NN; El-Mansy, AA; Firgany, AEL, 2017) |
| "Depression is a mental disorder, affecting the quality of life." | ( Anil Kumar, MN; Jois, SN; Mallikarjuna Majgi, S; Rajagopal, R; Shashidhar, HB, 2018) |
| "Depression is a severe and chronic mental disorder, affecting about 322 million individuals worldwide." | ( Bai, S; Chen, J; Chen, Z; Gui, S; Han, Y; Hu, Q; Huang, H; Liang, Z; Liu, Z; Shen, P; Wang, H; Wang, W; Xie, P; Xie, X; Zeng, L; Zhang, X, 2017) |
| "Late-life depression is characterized by both lower mood and poor cognitive performance, symptoms that often do not fully respond to current antidepressant medications." | ( Gandelman, JA; Newhouse, P; Taylor, WD, 2018) |
| "Depression is commonly associated with hypothalamic-pituitary adrenal (HPA) axis dysfunction that primarily manifests as aberrant glucocorticoid secretion." | ( Balmer, NJ; Caldwell, JL; Estrada, CM; Ghisays, V; Nguyen, ET; Solomon, MB; Streicher, J, 2018) |
| "Depression is a common psychiatric disorder that decreases the quality of life and increases the mortality of patients." | ( Chin, KY; Ima-Nirwana, S; Wong, SK, 2018) |
| "Since depression is known to be associated with HPA axis dysfunction and greater inflammation, a psychoneuroendocrinological (PNE) model of inflammation was examined in persons diagnosed with CFS in order to uncover underlying biopsychosocial mechanisms in this poorly understood chronic illness." | ( Antoni, MH; Czaja, SJ; Fletcher, MA; Hall, DL; Jutagir, DR; Klimas, N; Lattie, EG; Milrad, SF; Perdomo, DM, 2018) |
| "Depression is the most common mental disorder in the world." | ( Czarny, P; Galecki, P; Sliwinski, T; Su, KP; Wigner, P, 2018) |
| "Depression is a common psychiatric disorder and a leading cause of disability worldwide." | ( Carvajal-Lohr, A; Flores-Ramos, M; Rodríguez-Bores, L; Salinas, M, 2017) |
| "Depression is one of the leading causes of disability in developing countries including Pakistan." | ( Farooq, AD; Naqvi, S; Rahman, R; Zeb, F, 2017) |
| "Depression is a commonly occurring symptom in obsessive-compulsive disorder (OCD), and is associated with worse functional impairment, poorer quality of life, and poorer treatment response." | ( Ajilore, O; Deshpande, R; Feusner, JD; Ly, R; Moody, T; Morfini, F; O'Neill, J; Tadayonnejad, R, 2018) |
| "Post-myocardial depression is a highly prevalent condition which worsens the course and prognosis of coronary artery disease." | ( Landowski, J; Rynkiewicz, A; Wdowczyk, J; Wilkowska, A, 2019) |
| "Major depression is a common mental disorder that has been established to be associated with a decrease in serotonin and/or serotonin transporters in the brain." | ( Cheng, JT; Cheng, KC; Li, Y; Liu, KF; Niu, HS; Peng, WH, 2017) |
| "Depression is the most common mental health problem in aging persons and is a leading risk factor for physical disability, especially in women." | ( Appt, SE; Clarkson, TB; Justice, JN; Kritchevsky, SB; Register, TC; Shively, CA; Silverstein-Metzler, MG; Uberseder, B, 2017) |
| "Depression is a debilitating psychiatric disorder with a huge socioeconomic burden, and its treatment relies on antidepressants including selective serotonin reuptake inhibitors (SSRIs)." | ( Ji, YT; Li, K; Li, XY; Shen, S; Wang, XD; Zhang, LS, 2018) |
| "Depression is characterized by mental retardation, interest blank, hypoactivity, anxiety, appetite loss, sexual dysfunction, sleep disorders and other symptoms." | ( Cao, W; Li, L; Li, Y; Zhu, S, 2017) |
| "Depression is one of the most prevalent psychiatric disorders, and in older persons is associated with high levels of comorbidity and under-treatment." | ( Ancelin, ML; Lam, D; Ritchie, K; Ryan, J; Saffery, R, 2018) |
| "Depression is associated with an increased risk of Alzheimer's disease." | ( Bartels, C; Ehrenreich, H; Schneider, A; Wagner, M; Wolfsgruber, S, 2018) |
| "The development of depression is also associated with excessive activity of nitric oxide synthase." | ( Czarny, P; Galecki, P; Sliwinski, T; Wigner, P, 2017) |
| "Depression is a risk factor for T2D in the general population." | ( Banning, F; Ferrari, U; Freibothe, I; Gar, C; Künzel, H; Lechner, A; Moschko, S; Popp, D; Potzel, A; Reif, S; Sacco, V; Seissler, J; Sommer, NN; Tröndle, K; Wichmann, C, 2018) |
| "Depression is a nosological entity which may appear alone or concomitantly (e." | ( Kus, K; Nowakowska, E; Ratajczak, P; Skurzyńska, M, 2018) |
| "Depression is the main psychiatric comorbidity in epilepsy with an estimated prevalence between 20% and 55% and one of the main determinants of quality of life." | ( Becerra, JL; Bertol, V; Carreño, M; Ley, M; Mauri, JÁ; Molins, A; Rocamora, R; Sansa, G; Toledo, M, 2018) |
| "Depression is often associated with sexual dysfunction, and pharmacologic treatment for hypoactive sexual desire disorder can be considered in women receiving treatment for depression." | ( Brown, L; Clayton, AH; Croft, HA; Kissling, R; Yuan, J, 2018) |
| "Anxiety and depression are more frequent in TA patients than in general population as well as during relapses." | ( Komatina, N; Labović, B; Lepić, T; Obradović, D; Petronijević, M; Radovinović-Tasić, S; Stevović, T, 2016) |
| "Depression is characterized by a wide range of emotional, cognitive, and physical symptoms." | ( Bergman, YS; Bodner, E; Haber, Y, 2018) |
| "Poststroke depression is independently associated with poor health outcomes, such as increased mortality, disability, anxiety, and lower quality of life." | ( Chen, CL; Chen, CY; Ho, CH; Tseng, WC; Yang, YH, 2018) |
| "Depression is associated with accelerated aging and age-related diseases." | ( Aarsland, D; Lebedeva, A; Lindgren, L; Nyberg, L; Olsson, T; Stomby, A; Sundström, A; Westman, E; Winblad, B, 2018) |
| "Depression is a common, dysthymic, and psychiatric disorder, resulting in enormous social and economic burden." | ( Dong, LM; Fan, LX; Jiang, N; Liu, XM; Lu, C; Lv, JW; Pan, RL; Wang, Q; Zhang, BY; Zhang, HX, 2018) |
| "As depression is known to be a risk factor for suicide and many antidepressants are P-gp substrates, it has been speculated that inadequate antidepressant treatment response or adverse side effects could be involved." | ( Haukka, J; Palo, JU; Rahikainen, AL; Sajantila, A, 2018) |
| "From one hand, depression is one of the symptoms that occur after abstinence from methamphetamine." | ( Hashemi, SF; Jalali, F, 2018) |
| "Indeed, depression is associated with increased expression of interferon-γ, interleukin-1β, and tumor necrosis factor α (TNF-α)." | ( Barreto, FS; Chaves Filho, AJM; de Araújo, MCCR; de Lucena, DF; de Moraes, MEA; de Moraes, MO; Macedo, DS; Maes, M, 2018) |
| "Psychological depression is frequently linked to alcohol abuse and even serves as key indicators of an alcohol use disorder (AUD)." | ( Marshall, SA; Olney, JJ; Thiele, TE, 2018) |
| "Depression is a common non-motor symptom preceding motor symptoms in PD." | ( Dallé, E; Mabandla, MV, 2018) |
| "Perinatal depression is associated with serious risks for the mother, baby, and family." | ( Albertini, ES; Ernst, C; Fersh, ME; Habib, S; Khan, SJ; Lusskin, SI, 2018) |
| "Depression is the disease of the modern era." | ( Aboul-Fotouh, S; Asaad, T; Ghanem, MH; Habib, M; Kassim, SK, 2018) |
| "Geriatric depression is a major public health problem in China." | ( Cao, M; Li, Y; Ni, J; Tang, P; Xing, M; Xiong, M; Zhang, Y, 2018) |
| "Depression is an inflammatory, commonly occurring and lethal psychiatric disorder having high lifetime prevalence." | ( Barua, CC; Haloi, P; Pathak, DC; Ren, X; Rizavi, H; Saikia, B; Sulakhiya, K; Tamuli, S, 2018) |
| "Post-MI depression is a critical clinical problem, the comorbidity of which complicates depression treatment and worsens cardiovascular outcomes." | ( Fan, B; Jin, G; Liu, X; Wang, L; Wang, M; Xing, Y; Yuan, Y; Zhu, Q, 2018) |
| "Depression is a common psychiatric disorder with heavy economic and social burdens." | ( Gao, MH; Gong, Y; Hu, WF; Huang, C; Lu, X; Wang, P; Wu, Y; Yang, RR; Zhang, JL, 2018) |
| "Depression is one of the most common inflammatory and mental disorders." | ( Jang, JB; Jeong, HJ; Kim, HM; Kim, HY; Lee, HE; Nam, SY; Ryu, JH, 2018) |
| "Depression is an important comorbidity of epilepsy, which has been reported in patients with TLE and in different experimental models of epilepsy." | ( Alcará, AM; Azevedo, PN; DaCosta, JC; Feltes, PK; Greggio, S; Venturin, GT; Zanirati, G; Zimmer, ER, 2018) |
| "Depression is prevalent in primary biliary cholangitis (PBC) patients." | ( Almishri, W; Frolkis, AD; Kaplan, GG; Patten, S; Shaheen, AA; Swain, MG; Vallerand, I, 2018) |
| "Anxiety and depression are associated with worse outcomes in several cardiovascular conditions, but it is unclear whether they affect outcomes in atrial fibrillation (AF)." | ( Baumgartner, C; Fan, D; Fang, MC; Go, AS; Gurwitz, JH; Schmelzer, JR; Singer, DE; Sung, SH; Williams, MS; Witt, DM, 2018) |
| "Comorbid depression is common in patients with epilepsy." | ( Ding, J; Fan, F; Li, X; Peng, WF; Wang, X; Zhang, QQ, 2018) |
| "Depression is one of the leading causes of work disability." | ( Li, LMW, 2019) |
| "Both anxiety and depression are associated with difficulties in decision making." | ( Bishop, SJ; Gagne, C, 2018) |
| "Depression is a common affective disorder or mood disorder, which seriously affects people's physical and mental health and the quality of life." | ( Xiaoling, Z; Yingdong, L; Yunping, H, 2018) |
| "Depression is present in a large proportion of patients suffering from chronic pain, and yet the underlying mechanisms remain to be elucidated." | ( Ji, MH; Li, HH; Li, KY; Pan, W; Yang, JJ; Zhang, GF; Zhou, ZQ, 2018) |
| "Depression is a major public health problem which commonly starts during adolescence, thus identifying underlying mechanisms during early life is crucial in prevention." | ( Carvalho, LA; Clarke, G; Díaz, LE; Gómez-Martínez, S; Marcos, A; Michels, N; Olavarria-Ramirez, L; Widhalm, K, 2018) |
| "Depression is a common comorbidity in diabetes but conventional antidepressant treatments do not consistently improve outcomes." | ( Hopkins, CWP; Ismail, K; Moulton, CD; Stahl, D, 2018) |
| "Depression is a mental illness comorbid risk factor for glucose intolerance worldwide." | ( Ding, H; Jia, KK; Kong, LD; Liu, JH; Pan, SM; Pan, Y; Wang, SJ; Zheng, YJ, 2018) |
| "AD and depression are crucially linked by neuroinflammation and cyclooxygenase II (COX-2) enzyme involvement is an intriguing field of research." | ( Bove, M; Mhillaj, E; Morgese, MG; Schiavone, S; Trabace, L; Tucci, P, 2018) |
| "Depression is one of the leading causes of disability around the world." | ( Fan, Y; Han, X; Huang, X; Huang, Z; Li, X; Lu, C; Wang, X; Xia, Y; Xu, Q; Yu, M; Zhang, Y, 2018) |
| "Co-prevalence of depression is a significant issue and should always be screened for in patients with chronic pain, especially thus with aberrant drug behaviour." | ( Bingener, L; Bleckwenn, M; Just, JM; Schnakenberg, R; Weckbecker, K, 2018) |
| "Depression is one of the most common psychiatric symptoms in Alzheimer's disease (AD), and several studies have shown that oxidative stress plays a key role in the etiopathology of both AD and depression." | ( de Souza, V; Farina, M; Gonçalves, CL; Guerra de Souza, AC; Hartwig, JM; Prediger, RD, 2018) |
| "Depression is also common." | ( Cedars, MI; Greenwood, EA; Huddleston, HG; Legro, RS; Pasch, LA, 2018) |
| "Depression is associated with reduced quality of life related to polycystic ovary syndrome symptoms." | ( Cedars, MI; Greenwood, EA; Huddleston, HG; Legro, RS; Pasch, LA, 2018) |
| "Depression is one of the most frequent neuropsychiatric diseases in the western world and its physiological causes are not yet fully understood." | ( Camargo, A; da Silva, EB; Dalmagro, AP; Rikel, L; Simão da Silva, KAB; Zeni, ALB, 2018) |
| "Depression is a common mental disorder in adolescents, with a prevalence rate of 5." | ( Fang, G; Wang, Y, 2018) |
| "Antenatal depression is associated with a broad range of suboptimal outcomes in offspring, although the underlying mechanisms are not yet understood." | ( Biaggi, A; Chua, TE; Conroy, S; Du Preez, A; Hazelgrove, K; Nikkheslat, N; Osborne, S; Pariante, CM; Previti, G; Zunszain, PA, 2018) |
| "Depression is a highly prevalent disorder that affects more than 300 million adults worldwide in 2015." | ( Han, J; Li, K; Lin, L; Tian, H; Xia, Y; Zhang, Z, 2018) |
| "Late life depression is related to pathologic burdens, such as cerebral small vascular disease (CSVD) and amyloid, which are associated with brain network changes and cortical thinning." | ( Cho, SH; Ewers, M; Im, K; Jang, H; Kim, HJ; Kim, SE; Kim, SJ; Kim, ST; Kim, Y; Kwon, H; Moon, SH; Na, DL; Seo, SW, 2018) |
| "Late-life depression is a risk factor of dementia." | ( Chen, B; Chen, X; Gu, Y; Huang, X; Liang, W; Mai, N; Ning, Y; Ouyang, C; Pan, S; Peng, Q; Wu, Y; Wu, Z; Zhong, X, 2018) |
| "Late-life depression is associated with a greatly increased risk of reliable cognitive decline in short term." | ( Chen, B; Chen, X; Gu, Y; Huang, X; Liang, W; Mai, N; Ning, Y; Ouyang, C; Pan, S; Peng, Q; Wu, Y; Wu, Z; Zhong, X, 2018) |
| "Depression is currently not described as an ADR in the approved desloratadine product labelling." | ( Boer, J; Ederveen, E; Grundmark, B, 2018) |
| "Anxious depression is a common subtype of major depressive disorder (MDD) and is associated with greater severity and poorer outcome." | ( Busch, Y; Deckert, J; Domschke, K; Fietz, J; Lechner, K; Lehrieder, D; Leistner, C; Menke, A; Reitz, J; Stonawski, S; Weber, H; Wurst, C, 2018) |
| "Depression is twice more prevalent among women but remains unidentified in primary care." | ( Andrade, C; Anilkumar, TV; Indu, PS; Kumar, KA; Remadevi, S; Sarma, PS; Vijayakumar, K, 2018) |
| "Depression is associated with significant functional disabilities." | ( Akhondzadeh, S; Nejatisafa, AA; Roohi-Azizi, M; Sadat-Shirazi, MS; Torkaman-Boutorabi, A; Zarrindast, MR, 2018) |
| "Major depression is a psychiatric disorder with complex etiology." | ( Bayer, P; Béchade, C; Chabry, J; Debayle, D; Gay, AS; Guyon, A; Heurteaux, C; Maroteaux, L; Nicolas, S, 2018) |
| "Depression is a mental disorder that affects a large part of the world's population." | ( Cardoso, A; Grande, AJ; Mallmann, MB; Nardi, AE; Peixoto, C; Veras, AB, 2018) |
| "Anxiety and depression are significant modulators for patients' beliefs about substance use and depression is a modulator for craving and maladaptive beliefs, validating emotion-cognition interplay in addiction." | ( Arikan, Z; Eser, HY; Kotan, VO; Küçükkarapınar, M; Tarhan, R; Yalcinay-Inan, M, 2018) |
| "Depression is a worldwide illness with a significant impact on both family and society." | ( Cui, W; Hong, W; Li, MD; Liu, Z; Ning, Y; Wang, J, 2019) |
| "Depression is very common in asthmatic patients and may increases risk for morbidity and mortality." | ( Abo-Youssef, AM; Ismaiel, IE; Salama, AAA; Sherkawy, MM, 2018) |
| "Depression is one of the most common mental disorders characterized mainly by low mood and loss of interest or pleasure." | ( Cao, ZY; Gong, H; Jiang, CL; Lian, YJ; Liu, LL; Liu, YZ; Peng, W; Su, WJ; Wang, B; Wang, YX; Wu, R; Zhang, T; Zhang, Y, 2018) |
| "Anxiety and depression are more prevalent in IBD patients as compared to healthy individuals." | ( Adarkar, S; Bhamre, R; J Bhatia, S; Sakaria, R; Sawrav, S, 2018) |
| "Depression is currently treated by pharmacotherapies that can elicit debilitating side effects for patients." | ( Beidler, J; Hong, MY; Moore, A, 2018) |
| "Depression is a debilitating condition with a high prevalence." | ( Huys, QJM; Rupprechter, S; Seriès, P; Stankevicius, A; Steele, JD, 2018) |
| "Major depression is a multifactorial disease." | ( Guo, Y; Liu, S; Pan, W; Shen, Z; Wang, Z, 2018) |
| "Depression is a seriously disabling public health problem with very high world-wide prevalence." | ( Hirota, K; Kimura, F; Kudo, T; Nikaido, Y; Saito, J; Sawada, K; Takekawa, D; Yasui-Furukori, N, 2019) |
| "Resistant depression is still a common and burdensome issue and there is an urgent need for new and effective adjunctive treatments." | ( Serretti, A, 2018) |
| "Depression is common among patients with cardiovascular disease and has been associated with both drug non-adherence and increased mortality." | ( Burger, H; Hek, K; Holvast, F; Oude Voshaar, R; Schellevis, F; van Dijk, L; Verhaak, P; Wouters, H, 2019) |
| "Depression is associated with uncontrolled diabetes, which indicates a lack of insulin effect, yet the role of the insulin receptor in mediating depression is not clearly established because insulin receptors are not required for glucose entry into the brain." | ( Hajnal, A; Mueller, PL; Pritchett, CE; Wiechman, TN; Zharikov, A, 2018) |
| "Depression is a common condition affecting up to 20% of all pregnant women, and is associated with subsequent developmental and behavioral problems in children, such as conduct disorder and ADHD." | ( Bleker, LS; de Rooij, SR; Leeflang, MMG; Limpens, J; Roseboom, TJ; van Dammen, L, 2020) |
| "Migraine and depression are commonly linked and require expertise in treatment to achieve the best patient outcomes." | ( Cook, CL; Shedd, GC, 2018) |
| "Major depression is a common illness that severely limits psychosocial functioning and diminishes quality of life." | ( Malhi, GS; Mann, JJ, 2018) |
| "Depression is one of the major causes of disability worldwide." | ( Cubała, WJ; Gałuszko-Węgielnik, M; Górska, N; Słupski, J, 2018) |
| "Depression is a common mental illness with high morbidity and mortality." | ( Bai, X; Ding, Q; Li, P; Shi, X; Tang, B; Wu, C; Xiao, H; Zhang, W, 2018) |
| "Prevalence of depression is higher in patients with cancer than in the general population." | ( Andrews, N; Cabral, JE; Demers, M; Martinod, K; Suidan, GL; Wagner, DD, 2018) |
| "Depression is a mood disorder that is related to neuroinflammation and cognition loss." | ( Chu, C; Fu, S; Jia, M; Liu, X; Liu, Z; Pan, J; Wang, Q; Zhao, Y, 2019) |
| "Depression is a common occurrence among PLHIV and is elevated in those who consume alcohol." | ( Brault, MA; Ha, T; Irving, M; Prabhughate, P; Schensul, JJ; Schensul, SL; Vaz, M, 2019) |
| "Depression is one of the main non-motor symptoms of PD." | ( Haider, S; Madiha, S, 2019) |
| "Depression is a mental disease that causes severe economic and social burdens." | ( Chen, Z; Cheng, L; Huang, C, 2019) |
| "Depression is considered a neuropsychiatric disease associated with various neuronal changes within specific brain regions." | ( Fan, C; Li, Y; Song, Q; Wang, P; Yang, M; Yu, SY, 2018) |
| "Depression is commonly observed even in prodromal stages of Lewy body disorders (LBD), and is associated with cognitive impairment and a faster rate of cognitive decline." | ( Attems, J; Morris, CM; Patterson, L; Rushton, SP; Thomas, AJ, 2019) |
| "Depression is the root of various diseases." | ( Chen, H; Du, Y; Gao, Y; Li, W; Li, Y; Shi, H; Velez de-la-Paz, OI; Wang, X; Yang, J; Yin, S; Yin, X, 2019) |
| "The trend of depression is rising worldwide." | ( Abd Rahman, FN; Ang, AL; Hazmi, H; Md Yusoff, R; Wahab, S, 2019) |
| "Globally, depression is one of the most serious debilitating psychiatric mental disorders." | ( Ding, Y; Jiang, W; Li, C; Liu, M; Shi, S; Su, X; Sun, Y; Wang, Q; Wei, T; Yu, C; Zhang, J; Zhao, X, 2019) |
| "Anxiety and depression are common, highly comorbid psychiatric diseases that account for a large proportion of worldwide medical disability." | ( Barkley-Levenson, AM; Cohen, SM; Dick, BL; Glatt, PF; Martinez, Y; Momper, JD; Palmer, AA; Perez, C; Siegel, D, 2019) |
| "BACKGROUND Depression is a common disorder linked with high levels of chronicity, psycho-social and physical problems, and suicide." | ( Duan, H; Gao, C; Guo, B; Kong, S; Li, D; Liang, X, 2019) |
| "Schizophrenia and depression are highly associated with metabolic abnormalities." | ( Dmitrzak-Weglarz, M; Duda, J; Kapelski, P; Narozna, B; Pawlak, J; Rajewska-Rager, A; Skibinska, M; Szczepankiewicz, A; Twarowska-Hauser, J, 2019) |
| "Depression is highly prevalent in patients suffering from chronic inflammatory diseases." | ( Chen, N; Dong, XL; He, MC; Liao, DF; Peng, SY; Sha, NN; Shi, Z; Wang, YJ; Wong, MS; Yuan, TF; Zhang, Y, 2019) |
| "Depression is common among MS patients." | ( Aldossary, NM; Bedewi, MA; Kamal, AM; Kotb, MA, 2019) |
| "Depression is associated with decreased expression of brain-derived neurotrophic factor (BDNF) which assembled in Golgi apparatus." | ( Bai, X; Ding, Q; Guo, X; Li, P; Tang, B; Wang, X; Zhang, W, 2019) |
| "Depression is intimately linked with oxidative stress." | ( Ding, Q; Li, P; Tang, B; Wang, X; Wu, C; Zhang, W, 2019) |
| "Depression is associated with dysregulation of methyl group metabolism such as low S-adenosylmethionine (SAM)." | ( Geisel, J; Happ, DF; Mikkelsen, PF; Obeid, R; Tillmann, S; Wegener, G, 2019) |
| "Depression is highly prevalent among patients with chronic obstructive pulmonary disease (COPD)." | ( Deng, X; Fu, J; Guo, Q; Ji, Z; Ma, S; Song, Y; Xu, B, 2019) |
| "Depression is a common psychiatric disease which pharmacological treatment relieves symptoms, but still far from ideal." | ( Burger, ME; de David Antoniazzi, CT; Duarte, MM; Duarte, T; Kronbauer, M; Milanesi, LH; Rosa, HZ; Rossato, DR; Roversi, K, 2019) |
| "Depression is a frequent psychiatric complication after a stroke." | ( Accrombessi, D; Adoukonou, T; Agbétou, M; Houinato, D, 2019) |
| "Poststroke depression is a serious and common complication of stroke, especially the ischemic poststroke depression." | ( Bai, W; Ding, S; Gan, Y; Li, M; Li, P; Lu, H; Meng, L; Meng, Z; Ren, X; Wang, F; Wang, L; Wang, Z; Zhang, B; Zhang, C; Zhang, Z; Zhao, H, 2019) |
| "Depression is a heterogeneous disorder and associated with inflammatory responses." | ( Fernandes, J; Gupta, GL, 2019) |
| "Depression is a neuropsychiatry medical condition with high prevalence, in which the hypothalamic-pituitary-adrenal axis dysfunction has been postulated as the main cause." | ( Camargo, A; Dalmagro, AP; Zeni, ALB, 2019) |
| "Although depression is common among patients receiving maintenance hemodialysis, data on their acceptance of treatment and on the comparative efficacy of various therapies are limited." | ( Cohen, SD; Cukor, D; Dember, LM; Diaz-Linhart, Y; Dubovsky, A; Greene, T; Grote, N; Heagerty, P; Hedayati, SS; Kimmel, PL; Kutner, N; Mehrotra, R; Quinn, DK; Rue, T; Trivedi, MH; Unruh, M; Ver Halen, N; Weisbord, SD; Young, BA, 2019) |
| "Depression is a common comorbidity in cancer cases, but this is not only due to the emotional distress of having a life-threatening disease." | ( Mondelli, V; Nettis, MA; Pariante, CM; Sforzini, L, 2019) |
| "Depression is a major health issue that causes severe societal economic and health burden." | ( Chow, JK; Fung, TK; Lau, BW; Lau, WK; Po, KK; Sánchez-Vidaña, DI; So, PK; Tsang, HW, 2019) |
| "Depression is a debilitating mental illness and two thirds of patients respond insufficiently to conventional antidepressants." | ( Doudet, DJ; Hvilsom, AST; Iversen, P; Landau, AM; Lillethorup, TP; Wegener, G, 2019) |
| "Depression is a common but serious mental illness; meanwhile, it is also an inflammatory disorder." | ( Dang, H; Fu, S; Hao, C; Jiang, S; Wang, J, 2019) |
| "Depression is characterized by altered sensitivity to rewards, with recent evidence suggesting that the ability to sustain responses to rewards across long experimental tasks is diminished." | ( Berry, MP; Joormann, J; Sanislow, CA; Tanovic, E, 2019) |
| "Depression is an easily treatable yet frequently underdiagnosed affliction in palliative population with deleterious implications on their quality of life." | ( Abraham, B; George, C; Sudarisan, SSP, 2019) |
| "Depression is a complex disorder that takes an enormous toll on individual health." | ( Fox, ME; Lobo, MK, 2019) |
| "Major depression is a stress-linked disease with significant morbidity and the anesthetic drug ketamine is of growing interest in the treatment of depression, since in responsive individuals a single dose has rapid (within hours) antidepressant effects that can be sustained for over a week in some instances." | ( Fitzgerald, PJ; Watson, BO; Yen, JY, 2019) |
| "Depression is a prevalent disorder for patients with stroke." | ( Bai, ZF; Wang, LY, 2019) |
| "As depression is influenced by an array of psychological, biological, social, environmental, dietary, and lifestyle factors, it is hypothesised that treatment outcomes will only be improved when integrative interventions are utilised." | ( Lopresti, AL, 2019) |
| "Depression is one of the most prevalent and crucial public health problem connected to significant mortality and co-morbidity." | ( Farheen, S; Khanam, N; M, MMP; Mobarak Hossain, M; Shahi, MH; Tayyab, M, 2019) |
| "Although depression is the leading cause of disability worldwide, its pathophysiology is poorly understood." | ( Chen, F; Du, Y; Hong, H; Kong, L; Mei, Z; Meng, G; Reed, MN; Sun, H; Suppiramaniam, V; Tang, S; Yu, X, 2019) |
| "Depression is one the common psychiatric disorders through the world." | ( Amini-Khoei, H; Lorigooini, Z; Salimi, N; Soltani, A, 2019) |
| "Depression is common and results in a significant morbidity and economic burden." | ( Boyko, M; Brotfain, E; Frank, D; Frenkel, A; Grinshpun, J; Gruenbaum, BF; Gruenbaum, SE; Kutz, R; Zeldetz, V; Zlotnik, A; Zvenigorodsky, V, 2019) |
| "Depression is not yet fully understood, but various causative factors have been reported." | ( Kim, HJ; Lee, DK; Son, H; Yang, JH, 2019) |
| "Depression is a frequent comorbidity in patients with epilepsy." | ( Chrościńska-Krawczyk, M; Czuczwar, SJ; Miziak, B, 2019) |
| "Depression is a common disease that endangers people's physical and mental health." | ( Chu, L; Guan, Z; Liu, Y; Lu, Y; Pei, L; Sun, G; Yang, F; Zhang, Z; Zhao, J, 2019) |
| "Depression is a chronic and debilitating illness that interferes severely with many human behaviors, and is the leading cause of disability in the world." | ( Adell, A; Campa, L; Castro, E; Frago, C; Jiménez-Sánchez, L; López-Gil, X, 2019) |
| "Patients who have depression are significantly associated with a higher financial difficulty score, p<0." | ( Abdul Halim, H; Bee, PC; Chin, EFM; Gan, GG; Hidayat, TA; Leong, YC; Loo, H; Ng, DLC; Teh, AKH, 2019) |
| "Depression is a serious medical condition, typically treated by antidepressants." | ( Badura, J; Chelminiak, Z; Cuprys, M; Fraczek, J; Koszla, O; Koziorowski, M; Mytych, J; Solek, P; Tabecka-Lonczynska, A, 2019) |
| "Depression is a highly debilitating and life-threatening psychiatric disorder." | ( Li, Y; Liu, L; Ruan, J; Wang, H; Xiao, D, 2019) |
| "Treatment-emergent depression is a common complication in patients with chronic hepatitis C virus (HCV) infection undergoing antiviral combination therapy with IFN-α and ribavirin." | ( Bourlière, M; Bronowicki, JP; Chimienti, F; Cleophax, S; Doffoel, M; Lang, JP; Pujol, JF; Salvetat, N; Schwan, R; Van der Laan, S; Vire, B; Weissmann, D, 2019) |
| "Maternal depression is associated with disrupted neurodevelopment in offspring." | ( Broekman, BFP; Chong, YS; Fortier, MV; Gluckman, PD; Meaney, MJ; Pecheva, D; Poh, JS; Qiu, A; Shek, LP; Wang, Q; Zhang, H, 2020) |
| "Depression is one of the most common psychiatric disorders in the world." | ( Geng, J; Guo, W; Liu, J; Liu, W; Yuan, X, 2019) |
| "Depression is a chronic illness of unknown etiology." | ( Famitafreshi, H; Karimian, M, 2019) |
| "Depression is a disorder characterized by sustained negative affect and blunted positive affect, suggesting potential abnormalities in reward learning and its interaction with episodic memory." | ( Niv, Y; Rouhani, N, 2019) |
| "Depression is characterized by a marked decrease in social interactions and blunted sensitivity to rewards." | ( Chevallier, C; Palminteri, S; Safra, L, 2019) |
| "Depression is a common mental disease affecting a lot of people of all ages around the world." | ( Abdelmelek, H; Ammari, M; Lassoued, A; Othman, H; Sakly, M, 2019) |
| "Pain and depression are common in the population and co-morbid with each other." | ( Ferguson, E; James, RJE, 2020) |
| "Depression is a mental disease that significantly reduces the quality of patients' life." | ( Chen, H; Chen, J; Chen, X; Lin, J; Song, Z; Wu, Z; Yang, X; Zhao, R, 2019) |
| "Depression is a very common psychiatric disorder affecting approximately 300 million people worldwide with the prevalence being twice as high in women as in men." | ( Berger, S; Gureczny, S; Horvath, O; Pollak, DD; Reisinger, SN, 2019) |
| "Major depression is an important complication in patients with breast cancer, but is an underrecognized and undertreated condition in this population." | ( Gao, X; Li, H; Liu, Y; Wu, C; Zhang, S, 2019) |
| "Depression is a mental disorder that brings severe burdens to patients and their families." | ( Chen, S; Cheng, Y; Guo, W; Liu, Z; Qi, X; Zhou, J, 2019) |
| "Major depression is one of the most frequent psychiatric conditions." | ( Cubała, WJ; Gałuszko-Węgielnik, M; Górska, N; Jakuszkowiak-Wojten, K; Lisowska, KA; Szarmach, J; Szałach, ŁP; Słupski, J; Wiglusz, MS; Wilkowska, A; Włodarczyk, A, 2019) |
| "Background Depression is a psychiatric disease condition and the chronic mild stress (CMS) model is a well-known and valuable animal model of depression." | ( Arbid, MSS; El-Azma, MHA; El-Shamy, KA; El-Zayat, SR; Fadl, NN; Hosny, EN; Koriem, KMM; Morsy, FA; Youness, ER, 2019) |
| "Depression is considered a neuropsychiatric condition which is associated with neuronal injury within specific brain regions." | ( Fan, C; Feng, YB; Li, Y; Shen, J; Song, Q; Wang, L; Wang, P; Yu, SY, 2019) |
| "Depression is a complex disease that involves numerous factors, increasing evidences have showed that the level of 5-HT was lower in depressed patients and the administration of some selective serotonin re-uptake inhibitors exhibited antidepressant effects." | ( Ding, T; Du, X; Gong, W; Liu, F; Wang, L; Zhang, Y, 2019) |
| "Depression is the leading cause of mental health-related disease globally, and it affects an estimated 300 million people worldwide." | ( Fu, Z; Shen, Q; Wang, L; Xiao, Q; Xie, X; Xiong, Z; Yu, C; Zhou, J, 2019) |
| "Perimenopausal depression is a chronic recurrent disease that leads to an increased risk of suicide, and poses a significant risk to public health." | ( Cao, LH; Fang, XY; Huang, HY; Li, XM; Miao, MS; Qiao, JY; Zhang, R, 2019) |
| "Depression is associated with dietary factors and epigenetics." | ( Barker, ED; Cecil, CAM; Jacka, FN; Maughan, B; Mesirow, MSC; Relton, C; Roberts, S, 2019) |
| "Anxiety and depression are a major health burden." | ( Chrissobolis, S; DʼSouza, MS; Guisinger, TC; Norman, H; Seeley, SL, 2019) |
| "Depression is a psychiatric disorder with higher incidence in women." | ( Alvarez Silva, A; Fernández-Guasti, A, 2019) |
| "Depression is a disease that seriously threatens the quality of human life." | ( Cui, Q; Liu, Z; Wang, C; Wang, G; Yao, T; Zhang, Q, 2019) |
| "Depression is the third leading cause of disability in the world." | ( Corriger, A; Pickering, G, 2019) |
| "Depression is common among individuals with cannabis use disorder (CUD), particularly individuals who present to CUD treatment." | ( Baker, NL; Gilmore, AK; Gray, KM; Hood, CO; McClure, EA; McRae-Clark, AL; Sonne, SC; Squeglia, LM; Tomko, RL, 2020) |
| "Depression is a progressive and chronic syndrome and commonly related to several neuropsychiatric comorbidities, of which depression is the most studied." | ( Cao, YC; Liang, J; Sun, RL; Tang, CR; Wang, YX; Xu, LM; Yang, F; Ye, Z; Yu, XB; Zhang, HN, 2020) |
| "Pain and depression are highly prevalent symptoms in cancer patients." | ( Chen, S; Dai, J; Ding, Z; Guo, Q; Song, Z; Weng, Y; Xiong, Y; Xu, W; Yang, Y; Zhang, J; Zhang, JM; Zou, W, 2019) |
| "Depression is often triggered by prolonged exposure to psychosocial stressors and associated with coronary heart disease (CHD)." | ( Chen, Y; Dong, X; Hu, Y; Liu, P; Ma, H; Wang, Y; Yang, W; Zhang, T, 2020) |
| "Depression is associated with receipt of opioids in non-cancer pain." | ( Burge, S; Gebauer, S; Salas, J; Scherrer, JF; Schneider, FD; Witthaus, M; Zubatsky, M, 2020) |
| "Depression is highly comorbid with anxiety disorders and associated with profound cognitive impairment." | ( Chakraborty, S; Raju, TR; Shankaranarayana Rao, BS; Srikumar, BN; Tripathi, SJ, 2020) |
| "BACKGROUND Depression is a major mood disorder." | ( Cai, Y; Huang, W; Huang, Y; Li, P; Liu, S; Meng, X; Shi, J; Tang, B; Wang, Y; Zhu, A, 2019) |
| "Depression is a chronic and progressive syndrome and commonly associated with several neuropsychiatric comorbidities, of which depression is the most studied." | ( Cong-Rong, T; Fan, Y; Hai-Na, Z; Jing, L; Lei-Mei, X; Ruo-Lan, S; Xu-Ben, Y; Yan-Cheng, C; Ye-Xuan, W, 2020) |
| "Depression is a health problem that compromises the quality of life of the world's population." | ( Almeida, RN; Barboza, JN; Diniz, LRL; Sousa, DP; Souza, MTS, 2019) |
| "Anxiety and depression are often comorbid with neurological as well as other medical maladies." | ( Agarwal, RK; Das, D; Gajbhiye, A; Mishra, S; Patil, S; Sahu, A; Verma, E, 2020) |
| "Major Depression is a stress-related disorder characterized by altered hypothalamic-pituitary-adrenal axis function." | ( Beddig, T; Ebner-Priemer, U; Kirsch, P; Kuehner, C; Reinhard, I; Timm, C; Ubl-Rachota, B; Zamoscik, V, 2020) |
| "Depression is a common complication in Type 2 diabetes mellitus (T2DM); however, it has long been underrecognized and undertreated." | ( Chen, H; Chen, Q; Fang, W; Gao, Y; Shi, X; Tang, X; Wang, H; Wang, S; Wang, X; Yao, J, 2020) |
| "Depression is associated with immune dysregulation and the aberrant activity of the hypothalamic-pituitary-adrenal (HPA) axis." | ( Li, Y; Lin, W; Tang, M; Wang, X; Zhang, J; Zhang, K; Zhao, Y, 2020) |
| "Depression is a common comorbid condition with atopic dermatitis (AD), particularly during the active disease cycle." | ( Abildinova, G; Batpenova, G; Kirby, M; Kreinin, A; Pinhasov, A; Vinnik, T, 2020) |
| "Depression is a wide-spread disease that affects millions of people worldwide." | ( Chuang, HC; Hong, CJ; Su, CH, 2020) |
| "Depression is a highly prevalent mental disease and increasingly become a global public health problem." | ( Fang, XY; Li, YC; Lu, SF; Ming, B; Shen, JD; Wang, BY; Xu, EP; Zhu, LL, 2020) |
| "Considering that depression is an inflammatory related mental disease, this study investigated the antidepressant-like effects of water extract of P." | ( Chen, MH; Hsu, NY; Huang, YJ; Lin, SH; Lin, YE; Liu, WT; Lu, KH; Lu, YS; Sheen, LY, 2020) |
| "Depression is one of the most common neuropsychiatric disturbances in Parkinson's disease (PD), but its pathophysiology is not definite." | ( Guo, Y; Hu, W; Jiang, YF; La, XM; Liu, J; Wang, HS; Xie, W; Yang, J; Zhang, J; Zhang, L, 2020) |
| "Depression is characterized by significant and low mood." | ( Cong, Y; Liu, H; Zhou, Y, 2020) |
| "Anxiety and depression are common among psoriasis and psoriatic arthritis (PsA) patients, but rates may differ by treatment." | ( Hagberg, KW; Jick, S; Persson, R; Vasilakis-Scaramozza, C, 2020) |
| "Depression is one of the most common psychiatric diseases and the prevalence of depressive symptoms in women is almost twice compared to men, although the reasons of this gender difference are not fully understood yet." | ( Maffione, AB; Morgese, MG; Schiavone, S; Trabace, L; Tucci, P, 2020) |
| "Depression is a long term inhibitory mood that heavily disabled human beings." | ( Jiang, CY; Lan, R; Lang, XY; Li, XX; Qin, XY; Yu, Y, 2020) |
| "Depression is a serious global affective disorder and one of the most common neurological diseases." | ( Lu, J; Meng, D; Miao, Z; Pan, K; Wan, B; Zhang, J; Zhou, H, 2020) |
| "Depression is one of the most common mentally debilitating diseases in the world." | ( de Abreu, GR; Fukushima, AR; Manes, M; Moreira, N; Ricci, EL; Spinosa, HS; Waziry, PAF; Zaccarelli-Magalhães, J, 2020) |
| "Depression is one of the major causes of disability in societies worldwide." | ( Cao, S; Liu, S; Tang, M; Wang, L; Wu, C; Xue, Y; Zeng, M; Zheng, YI, 2020) |
| "Depression is considered a common mental disorder that affects more than 300 million people worldwide." | ( Bochi, GV; Burger, ME; Pereira, GC; Roversi, K; Trevisan, G, 2020) |
| "Depression is a worldwide health problem." | ( Mizushige, T; Ohinata, K; Uchida, T, 2020) |
| "Depression is characterized by behavioral, cognitive and physiological changes, imposing a major burden on the overall wellbeing of the patient." | ( Bromberg, E; de Vries, EFJ; Dierckx, RAJO; Doorduin, J; Giacobbo, BL; Moraga-Amaro, R; Nazario, LR; Schildt, A, 2020) |
| "Depression is still one of challenging, and widely encountered disorders with complex etiology." | ( Al-Rasheed, N; Attia, HA; Badr, AM, 2020) |
| "Midlife depression is likely influenced by both menopause- and nonmenopause-related factors." | ( Soares, CN, 2020) |
| "Women with depression are more than three times more likely to use cannabis during pregnancy." | ( Das Eiden, R; Goodwin, RD; Heisler, Z; Metz, TD; Wu, M; Wyka, K; Zhu, J, 2020) |
| "Depression is a serious disorder characterized by imbalance of mood and emotions, which is accompanied by the reduction in the monoaminergic signaling." | ( Bilheri, FN; Nogueira, CW; Sampaio, TB; Zeni, GR, 2020) |
| "Depression is a common disease that afflicts one in 6 people." | ( Chen, J; Chen, Z; He, H; Huang, C; Li, Y; Liu, R; Ma, Y; Qiu, J; Tong, L; You, Q, 2020) |
| "Although depression is commonly characterized by reduced RR, depressed adolescents with active suicidality exhibited relatively enhanced neural responses to reward and loss feedback." | ( Dickey, L; Green, H; Kujawa, A; Pegg, S, 2020) |
| "Depression is a common mental health disorder that can impair normal functions, cause distress, and adversely affect the quality of life." | ( Bai, S; Cai, Q; Cao, K; Jiang, Z; Shen, C; Shi, Y; Yang, L; Ye, R; Zhang, M; Zhang, R; Zhang, S, 2020) |
| "Depression is a symptom of Parkinson's disease (PD) and may be correlated with cardiovascular sympathetic function." | ( Bono, K; Iguchi, Y; Komatsu, T; Maku, T; Mitsumura, H; Motegi, H; Murakami, H; Nakada, R; Omoto, S; Sakai, K; Sato, T; Shiraishi, T; Takahashi, M; Takatsu, H; Umehara, T, 2020) |
| "Depression is the leading cause of disability worldwide." | ( Bock, A; Engmann, O; Hübner, CA; Trautmann, C; Urbach, A, 2020) |
| "Depression is one of the most common mood disorders, which affects one in six people at some point in life." | ( Bochi, GV; da Silva, RM; Dalenogare, DP; de Almeida, AS; Dos Santos, BM; Dos Santos, GT; Fialho, MFP; Marchesan, S; Moresco, RN; Pereira, GC; Piton, E; Schiefelbein, NS, 2020) |
| "Depression is common in older people and is associated with underlying brain change increasing the risk of dementia." | ( Gordon, C; Hickie, IB; Hoyos, CM; Lewis, SJG; Naismith, SL; Norrie, L; Terpening, Z, 2020) |
| "Depression is a mental illness with a high prevalence in humans reaching 21% of the worldwide population." | ( Abd Rabo, AA; Abd-El Daim, TM; Elfeky, AS; Fahmy, HM; Khadrawy, YA; Mostafa, IT; Mustafa, AB, 2020) |
| "Depression is a common mental health problem among the elderly populations." | ( Ibrahim, Z; Mesbah, SF; Shariff, ZM; Sulaiman, N, 2020) |
| "Depression is the most significant cause of suicide among neuropsychiatric illnesses." | ( Alese, OO; Mabandla, MV; Mkhize, NV; Ngoupaye, GT; Rakgantsho, C; Zulu, S, 2020) |
| "Depression is a common mental disorder in the elderly population, which significantly impacts their quality of life." | ( Bairwa, M; Behera, P; Behera, SM; Dabar, D; Gupta, SD; Mohan, V; Pilania, M; Poongothai, S; Yadav, V, 2020) |
| "Depression is characterized by difficulties regulating emotions, which may result from executive control impairment." | ( Joormann, J; Quinn, ME, 2020) |
| "Major depression is a serious, but common, psychological disorder, which consists of a long-lasting depressive mood, feelings of helplessness, anhedonia, and sleep disturbances." | ( Chen, ZK; Dong, H; Huang, ZL; Jiang, SY; Li, RX; Ni, J; Qu, WM; Wang, TX; Yuan, MY, 2020) |
| "Postoperative depression is one of the most common mental disorders in patients undergoing cancer surgery and it often delays postoperative recovery." | ( Ding, J; Duan, G; Feng, L; Li, C; Li, H; Wang, K; Wang, M; Wu, Z; Yang, G; Zhao, P, 2020) |
| "Novel therapies for depression are required to better treat this population." | ( Dinoff, A; Klepacz, L; Lynch, ST; Sekhri, N, 2020) |
| "BACKGROUND Depression is the 5th most prevalent disorder adversely affecting the health of humans worldwide." | ( Chen, H; Liu, L; Wang, N; Wang, X; Yang, T, 2020) |
| "Depression is a common non-motor symptom in patients with Parkinson's disease (PD) and difficult to treat." | ( Chen, G; Liu, H; Lu, L; Tang, J; Tao, W; Wang, K; Wang, Q; Wei, F; Wu, D; Xu, L; Xue, W; Zhou, T, 2020) |
| "Depression is an emotional disorder that causes mental and physical changes, and has limited pharmacotherapy." | ( Bona, NP; de Farias, AS; de Oliveira Campello Felix, A; Luduvico, KP; Pedra, NS; Soares, MSP; Spanevello, RM; Spohr, L; Stefanello, FM; Teixeira, FC, 2020) |
| "Maternal depression is associated with instability within the family environment and increases in offspring substance use across adolescence." | ( Chronis-Tuscano, A; Cinader, M; Collado, A; Felton, JW; Lejuez, CW; Yi, R, 2021) |
| "Depression is a mood disorder with high global prevalence." | ( Amini-Khoei, H; Anjomshoa, M; Bagheri, E; Boroujeni, SN; Lorigooini, Z, 2020) |
| "Depression is common in patients with myocardial infarction (MI), attributing to worse outcomes." | ( Ge, Y; Liu, M; Xu, W; Zhang, L, 2020) |
| "Depression is one of the most common but serious psychiatric disorders affecting millions of people globally, which has become increasingly prevalent during the past few decades." | ( Li, L; Zhang, J; Zhang, Y, 2020) |
| "Depression is the most common extrahepatic neuropsychiatric manifestation in chronic hepatitis C (CHCV) and is due to direct neuropathogenic mechanisms." | ( Abdel Moez, AT; Al Balakosy, AM; El Hawary, YA, 2021) |
| "Depression is a highly prevalent and heterogeneous disorder." | ( Badini, I; Breen, G; Coleman, JRI; Fabbri, C; Hagenaars, SP; Hotopf, M; Lewis, CM, 2022) |
| "Depression is one of main symptoms accompanying thermal hyperalgesia and mechanical allodynia induced by inflammatory pain." | ( Fang, A; Li, Y; Wu, B; Wu, X; Zhang, Y, 2020) |
| "Depression is highly related to Alzheimer's disease (AD), yet no effective treatment is available." | ( Chen, W; Fu, HR; Gao, YF; Wang, H; Wang, L; Wang, XD; Xu, XY; Xu, Y; Zhang, FF; Zhang, HT; Zhang, JG, 2020) |
| "Depression is a common mental illness that possesses a noteworthy effect on patients' lives." | ( Badary, OA; El-Naga, RN; Gad, AM; Hassan, MM; Menze, ET, 2020) |
| "Depression is recognized as a highly chronic and recurrent disorder." | ( Allen, J; Caruncho, HJ; Kalynchuk, LE; Kulhawy, EY; Lebedeva, KA, 2020) |
| "Depression is one of the most common mental disorders with an increasing incidence." | ( Hui, L; Liu, J; Liu, L; Lv, W; Zheng, K; Zhu, C, 2020) |
| "Depression is a major health problem for which most patients are not effectively treated." | ( Bowman, MA; Daws, LC; Horton, RE; Koek, W; Mitchell, NC; Owens, WA, 2020) |
| "Mostly, stress and depression are associated with coronavirus disease infection and thus, resulting in weakening of patients' immune response and hence, more severe respiratory symptoms or even death." | ( Hagag, RS; Hamed, MGM, 2020) |
| "Depression is the most significant risk factor for suicide, yet the causes are complex and disease mechanism remains unclear." | ( Guo, SY; Han, XM; Huang, F; Jiao, ML; Liu, HR; Zhan, HQ; Zhao, ZH, 2020) |
| "Depression is a common mental disorder affecting more than 300 million people worldwide and is one of the leading causes of disability among all medical illnesses." | ( Ho, YC; Hsieh, MC; Lai, CY; Lee, AS; Lin, TB; Peng, HY; Wang, HH; Yang, PS, 2020) |
| "Depression is one of the most common forms of mental illness and also a leading cause of disability worldwide." | ( Chen, TT; Gao, TT; Guan, W; Jiang, B; Liu, L; Wang, JL; Wang, Y; Wang, YJ; Zhao, J, 2020) |
| "Pain and depression are often co-existing pathological states that promote mutual severity resulting in limited efficacy of current treatment strategies." | ( Bhatti, R; Garg, S; Kaur, A; Singh, L, 2021) |
| "The burden of depression is enormous, and numerous studies have found that major depressive disorder (MDD) induces cardiovascular disorders (CVD) and functional dyspepsia (FD)." | ( Chen, K; Huang, X; Huang, Y; Liu, J; Liu, X; Nie, B; Ren, P; Shen, X; Wu, L; Xu, M; Zhang, T; Zhou, J, 2021) |
| "Depression is one of the most common behavioral and psychological symptoms in people with Alzheimer's disease (AD)." | ( Jia, J; Li, T; Quan, M; Wang, W; Wei, C, 2020) |
| "Depression is a mental disorder that affects millions of people around the world." | ( Barciela Veras, A; Cardoso, A; Gomes Carrilho, C; José Grande, A; Nardi, AE; Peixoto, C, 2020) |
| "Depression is a highly debilitating psychiatric disorder and a worldwide health issue." | ( Musazzi, L, 2021) |
| "BACKGROUND Depression is the main problem of psycho-nephrology." | ( Chang, W; Gao, B; Han, Y; Hao, J; Li, J; Qi, P; Song, X; Sun, N; Uchida, S; Zhang, M, 2020) |
| "Depression is likely associated with earlier BUP treatment dropout." | ( Ballantyne, JC; Copeland, LA; Grucza, R; Lustman, PJ; Salas, J; Scherrer, JF; Sullivan, MD, 2021) |
| "Anxiety and depression are symptoms associated with ethanol withdrawal that lead individuals to relapse." | ( Albino, MC; André, E; de Paula Soares, V; de Sousa Pinto, ÍA; Dos Santos, LC; Gavioli, EC; Holanda, VAD; Junqueira Ayres, DD; Lima, RH; Padovan, CM; Silveira, MA, 2021) |
| "Postpartum depression is a mood disorder with a distinct neurobiological and behavioural profile occurring during and after the postpartum period." | ( George, SR; Hasbi, A; Milenkovic, M; Noori, M; Sivasubramanian, M, 2020) |
| "Depression is a common aspect of the modern lifestyle, and most patients are recalcitrant to the current antidepressants." | ( Feng, T; Gan, X; Guo, Y; Long, X; Pu, S; Ren, C; Tang, H; Zhou, H, 2020) |
| "Depression is closely linked to hypothalamus-pituitary-adrenal axis hyperactivity." | ( Chang, HS; Duan, XH; Hu, KL; Li, LN; Li, Y; Liu, M; Yu, X; Zhang, B, 2020) |
| "Depression is a disorder of dysregulated affective and social functioning, with attenuated response to reward, heightened response to threat (perhaps especially social threat), excessive focus on negative aspects of the self, ineffective engagement with other people, and difficulty modulating all of these responses." | ( Eckstrand, KL; Forbes, EE; Rofey, DL; Silk, JS, 2021) |
| "Depression is a common disorder that can lead to suicidal behaviours among the geriatric population." | ( Arafat, SY; Hakak, SA; Islam, SMS; Shoib, S, 2021) |
| "Early childhood depression is associated with anhedonia and reduced event-related potential (ERP) responses to rewarding or pleasant stimuli." | ( Barch, DM; Gilbert, K; Hajcak, G; Kappenman, ES; Kelly, D; Luby, JL; Whalen, D, 2020) |
| "Depression is a complex and heterogeneous mental disorder." | ( Bian, HT; Huang, JJ; Liang, L; Wang, GH; Wang, HL; Xiao, L, 2020) |
| "Depression is common in patients with rheumatoid arthritis (RA), exacerbates disease activity, and may decrease response to first-line disease-modifying antirheumatic drugs." | ( Barton, JL; England, BR; Hochberg, MC; Mikuls, TR; Rathbun, AM; Ryan, AS; Shardell, MD, 2021) |
| "In early RA, depression is associated with greater short-term disease activity during MTX treatment, as well as more persistent and severe pain." | ( Barton, JL; England, BR; Hochberg, MC; Mikuls, TR; Rathbun, AM; Ryan, AS; Shardell, MD, 2021) |
| "Depression is considered a psychological risk factor for Alzheimer's disease (AD)." | ( Dong, PQ; Ma, YH; Ou, YN; Shen, XN; Tan, PL; Wang, ZT; Yu, PJ, 2021) |
| "Depression is intimately linked with oxidative stress in the brains." | ( Ding, Q; Li, P; Su, D; Tang, B; Tian, Y; Wang, X; Wu, C; Zhang, W, 2020) |
| "Depression is one of the most common associated diseases, which aggravates psoriatic skin lesions and affects the life quality of patients." | ( Di, T; Guo, J; Guo, X; Li, P; Liu, Y; Meng, Y; Qi, C; Wang, Y; Zhang, L; Zhao, J, 2020) |
| "Depression is one of the most common psychiatric disorders, and there is strong demand for developing novel antidepressants with better efficacy and less adverse effects." | ( Gu, JH; Ji, CH; Jiang, B; Liu, Y; Tang, WQ; Zhang, Y; Zhao, J, 2021) |
| "Depression is characterized by a pattern of maladaptive emotion regulation." | ( Bartholow, BD; Bell, DJ; Irvin, KM; Steinley, D, 2022) |
| "Depression is a serious medical illness that is one of the most prevalent psychiatric disorders." | ( Hwang, DY; Hyun, SA; Ka, M; Kim, HR; Ko, MY; Lee, BS; Lee, CY; Lee, YJ, 2020) |
| "Depression is a major psychological disorder that contributes to global health problem." | ( Ahmed-Farid, OA; El Awdan, SA; El-Marasy, SA; Hassan, A; Ogaly, HA, 2021) |
| "Depression is the most prevalent psychological disorder as assessed by GHQ28 and Present State Examination in survivors of acute ischemic stroke." | ( Badwaik, DG; Badwaik, P, 2021) |
| "Depression is an important co-morbidity in persons with epilepsy (PWE) and its timely identification is essential." | ( Katyal, J; Rashid, H; Sood, M; Tripathi, M, 2021) |
| "Depression is a risk factor for nicotine use and withdrawal." | ( Gilbert, DG; Newcomer, JW; Pergadia, ML, 2020) |
| "Depression is a pervasive or persistent mental disorder that causes mood, cognitive and memory deficits." | ( Dai, SF; Deng, XP; Huang, HL; Li, S; Liang, JH; Liu, CQ; Luan, ZL; Ma, XC; Qiao, YL; Sun, CP; Yu, ZL; Zhang, ZJ; Zhou, JJ, 2021) |
| "Depression is more common among older adults, but there is a paucity of information about its association with spiritual intelligence." | ( Jayaram, S; Kumar, SS; Roy, PK; Saya, GK; Ulaganeethi, R, 2021) |
| "Depression is associated with abnormalities in Hypothalamic-Pituitary-Adrenal (HPA) axis functioning and neural circuitry that underlie the stress response." | ( Cullen, KR; Klimes-Dougan, B; Mueller, BA; Schreiner, MW; Thai, M, 2021) |
| "Major depression is a frequent and disabling disorder." | ( Blier, P; Desfossés, CY, 2021) |
| "Depression is a common morbidity after traumatic brain injury." | ( Carvalho, AF; Chen, TY; Chen, YW; Cheng, YS; Chu, CS; Hsu, CW; Lei, WT; Li, DJ; Liang, CS; Lin, PY; Stubbs, B; Sun, CK; Tseng, PT; Tu, YK; Wu, CK; Wu, MK; Wu, YC; Yeh, TC, 2021) |
| "Late-life depression is common and often inadequately managed using existing therapies." | ( Agustini, B; Berk, M; Dodd, S; Fitzgerald, PB; Fitzgerald, SM; Lockery, JE; Mazza, C; McNeil, JJ; Mohebbi, M; Murray, AM; Nelson, MR; Reid, CM; Shah, RC; Stocks, N; Storey, E; Wolfe, R; Woods, RL, 2021) |
| "Major Depression is a severe psychiatric condition with a still poorly understood etiology." | ( Adell, A; Castro, E; Díaz, Á; Florensa-Zanuy, E; Garro-Martínez, E; Mac-Dowell, KS; Martín-Hernández, D; Pazos, Á; Pilar-Cuéllar, F, 2021) |
| "Anxiety and depression are both characterized by dysregulated autonomic reactivity to emotion." | ( De Zorzi, L; Honoré, J; Ranfaing, S; Sequeira, H, 2021) |
| "Treatment of depression is hampered by the failure to identify distinct symptom profiles with distinct pathophysiologies that differentially respond to distinct treatments." | ( Chamli Hårsmar, S; Lindahl, J; Lindqvist, D; Söderberg, G; Suneson, K, 2021) |
| "Depression is a disabling psychiatric disorder affecting millions of people all around the world." | ( Amini-Khoei, H; Dehpour, AR; Ershadi, ASB; Hosseini, MJ, 2021) |
| "In hyperthyroidism, depression is more severe." | ( Coșa, LE; Cozma, MM; Mihai, A; Pápai, A, 2021) |
| "Pathways to depression are complex, and research testing interactions between multiple factors is needed." | ( Arfer, KB; Kujawa, A; Pegg, S, 2021) |
| "Depression is a neuropsychiatric disorder and has intrauterine developmental origins." | ( Chen, L; Dai, S; Hu, S; Jiang, T; Li, K; Li, X; Luo, M; Wang, H; Wang, T; Xu, D; Yi, Y, 2022) |
| "Depression is one of the most frequent psychiatric comorbidities associated with epilepsy having a major impact on the patient's quality of life." | ( Goel, RK; Singh, T, 2021) |
| "Depression is a psychiatric disorder that has a significant health burden on patients and their families." | ( Anoopkumar-Dukie, S; Davey, AK; Zhang, Y, 2021) |
| "Poststroke depression is a common secondary mental disorder after stroke, which increases the recurrence rate and mortality rate after stroke and hinders the recovery of function." | ( Bi, J; Gao, L; Gong, P; Ma, X, 2021) |
| "Depression is a common and serious psychiatric disorder, but current conventional antidepressants have limited efficacy and significant side effects." | ( Cao, C; Guan, T; Hou, Y; Jia, S; Li, S; Li, Y; Wei, X; Zhao, X, 2021) |
| "Depression is the single largest contributor to global disability with a huge economic and social burden on the world." | ( Akhtar, MJ; Kumar, B; Kumar, RR; Pathania, S; Sahu, B; Singh, PK, 2021) |
| "Depression is the most common psychiatric comorbidity of epilepsy." | ( Dehpour, AR; Hemmati, S; Mohammadi, S; Sadeghi, MA; Vafaei, A; Yousefi-Manesh, H; Zare, M, 2021) |
| "Depression is a common and disabling mental disorder with high recurrence rate." | ( Amin, N; Chen, F; Chen, S; Fang, M; Jin, W; Liu, J, 2021) |
| "Depression is one of the most complex multifactorial diseases affected by genetic and environmental factors." | ( Gao, Y; Li, X; Ling-Hu, T; Qin, XM; Tian, JS; Zhao, HL; Zhou, YZ, 2021) |
| "Depression is associated with altered functional connectivity and altered cortisol sensitivity, but the effects of cortisol on functional connectivity in depression are unknown." | ( Abercrombie, HC; Birn, RM; Ladd, CO; Meyerand, ME; Rivera-Bonet, CN, 2021) |
| "Geriatric depression is common and is often associated with coexisting medical illnesses, cognitive dysfunction, or both." | ( Britt, RB; Brown, JN; Kahlon, CH; Smith, KR, 2021) |
| "Depression is one of the most common neuropsychiatric disorders." | ( Dan, D; He, K; Liu, J; Nie, L; Xu, J; Yang, C; Yang, X; Zhang, CE; Zhang, K, 2021) |
| "While depression is the most frequent psychiatric disorder among the older adults, the use of water and sanitation has been associated with both physical and psychological adverse outcomes." | ( Bagayoko, M; Gyasi, RM; Simiyu, S, 2022) |
| "Depression is a widespread and devastating mental illness and the search for rapid-acting antidepressants remains critical." | ( Cole, AB; Hesselgrave, N; Thompson, SM; Troppoli, TA; Wulff, AB, 2021) |
| "Depression is a psychiatric disorder with several comorbidities that has a complicated pathophysiology." | ( Amiri, S; Gauvin, E; Peeri, M; Pirri, F; Zolfaghari, FS, 2021) |
| "Depression is a common, chronic, and often recurrent serious mood disorder." | ( Adelvane de Paula Rodrigues, F; Barbosa-Filho, JM; Cavalcanti Capibaribe, VC; Chavez Gutierrez, SJ; de Castro Chaves, R; Ferreira de Oliveira, N; Florenço de Sousa, FC; Lopes Sales, IS; Maia Oliveira, IC; Maria de França Fonteles, M; Rodrigues de Carvalho, AM; Rodrigues, GC; Teodorio Vidal, LM; Vasconcelos Mallmann, AS, 2022) |
| "Anxiety and depression are the most common withdrawal symptoms of methamphetamine (METH) abuse, which further exacerbate relapse of METH abuse." | ( Gong, Q; Huang, X; Jiang, P; Kendrick, K; Li, J; Li, L; Lu, L; Sun, J; Zhou, X, 2021) |
| "Depression is responsible for 800 000 deaths worldwide, a number that will rise significantly due to the COVID-19 pandemic." | ( Efferth, T; Naß, J, 2021) |
| "Depression is closely related to overactivation of N-methyl-d-aspartic acid (NMDA) receptors, and Zn2+ is a vital NMDA receptor modulator involved in the pathophysiological and physiological processes of depression." | ( Feng, J; Li, JZ; Li, SP; Mao, XM; Wang, CY; Wang, Q, 2021) |
| "Depression is a common and heterogeneous mental disorder." | ( Chai, T; Duan, J; Fang, L; Hu, X; Huang, Y; Ji, P; Li, Y; Song, J; Tan, X; Wu, J; Xie, P; Yang, D; Zhang, H; Zhao, L; Zheng, P, 2021) |
| "Major depression is a serious psychiatric disorder, occurring in up to 20 % of the population." | ( Brown, SJ; Huang, XF; Newell, KA, 2021) |
| "Depression is the second chronic disease, as a source of the global burden of disease, after heart disease." | ( Kandeil, MA; Khalaf, MM; Mahmoud, HA; Salama, A, 2021) |
| "Depression is a complex neuropsychiatric disease involved multiple targets and signaling pathways." | ( Fang, YY; Su, HF; Tian, Q; Wang, XM; Ye, CY; Zeng, P; Zhang, T, 2021) |
| "Depression is commonly observed in university students, who are a high risk group for developing psychiatric disorders during adulthood." | ( Foo, CN; Lim, YM; Mohd-Sidik, S; Najar Singh, JK; Ng, FL; Pheh, KS; Tang, PY; Yap, SY, 2021) |
| "Depression is an important global health issue that is associated with serious physical and mental health consequences." | ( Chen, Y; Qin, X; Shan, W; Tang, L; Yu, H; Yu, Z, 2021) |
| "Depression is one of the leading causes of death worldwide." | ( Abdelfatah, S; Efferth, T; Naß, J, 2021) |
| "Depression is the leading cause of disability around the world; however, most antidepressants have drug tolerance and serious side effects." | ( Chen, Y; Gao, T; Huang, D; Wan, M; Weng, Z; Wu, Y; Yan, F; Zhang, Y; Zhong, Y, 2021) |
| "Depression is linked to an increased risk of cognitive decline and dementia; therefore, failing to diagnose and treat LLD in later life may have significant health implications." | ( Meher, T; Muhammad, T, 2021) |
| "Depression is a severe mental disorder." | ( Chen, Z; Dai, L; Hu, J; Wang, M; Wang, Y; Wu, G; Wu, X; Xi, C; Yang, L, 2021) |
| "Depression is a common mental health problem that is thought to develop through a combination of genetic, psychological, and environmental factors, including parental behaviours and parental mental health." | ( Åslund, C; Keijser, R; Nilsson, KW; Olofsdotter, S, 2021) |
| "Depression is a prevalent PD-associated symptom and is often associated with reduced quality of life." | ( Bang, Y; Choi, HJ; Lim, J, 2021) |
| "Depression is associated with blunted reactivity to acute stress, as well as blunted responsivity to rewards." | ( Cunningham, S; Harkness, KL; Kennedy, S; Mazurka, R; Milev, RV; Pizzagalli, DA; Wynne-Edwards, KE, 2021) |
| "Depression is a syndrome characterized by deep sadness and the inhibition of psychic functions, sometimes accompanied by neurovegetative disorders, with symptoms of anxiety almost always present." | ( Moragrega, I; Ríos, JL, 2022) |
| "Depression is a common and serious mental illness that begins early in life." | ( Anderson, RZ; Chaplin, AB; Daniels, NF; Gregory-Jones, A; Jones, PB; Khandaker, GM; Ples, D, 2023) |
| "Depression is prevalent in patients managed with warfarin and is associated with significant decreases in TTR." | ( Anderson, JL; Bair, TL; Bunch, TJ; Knight, S; Knowlton, KU; May, HT; Muhlestein, JB; Rizzi, SA; Steinberg, BA; Stevens, SM; Woller, SC, 2021) |
| "Depression is a chronic and debilitating psychiatric disorder that affects 300 million people worldwide." | ( Akhondzadeh, S; Shamabadi, A, 2021) |
| "Depression is a mental disorder that profoundly affects all aspects of life, but currently, antidepressants have some problems with their effectiveness and side effects." | ( Ardianto, C; Budiatin, AS; Khotib, J; Nurrahmi, N; Rahmadi, M; Sumartha, INB, 2021) |
| "Depression is one of the most common and disabling mental disorders." | ( Li, N; Shi, HJ; Sun, YQ; Wang, S; Zhu, LJ, 2021) |
| "Depression is considered as one of the most common neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) patients." | ( Bai, Y; He, Y; Huang, J; Huang, S; Huang, W; Li, H; Li, Y, 2021) |
| "Depression is one of the most common mental health disorders and it is generally characterized by negative mood." | ( Alizadeh Makvandi, A; Amiri Moghaddam, S; Khalili, M; Roghani, M, 2021) |
| "Adolescent depression is increasing during the COVID-19 pandemic, possibly related to dramatic social changes." | ( Hutchinson, E; Jones, NP; Ladouceur, CD; Sequeira, SL; Silk, JS, 2021) |
| "Depression is associated with reduced motivation to engage in previously enjoyed activities." | ( Horne, SJ; Quigley, L; Topp, TE, 2021) |
| "Depression is a serious neuropsychiatric disorder, which is characterized by sustaining mood disorders." | ( Han, Y; He, J; Pan, CH; Shi, R; Wang, YM; Wang, ZX; Xia, CY; Xu, JK; Yan, Y; Zhang, WK, 2021) |
| "The incidence of depression is twice higher in women than in men, and gender differences in the prevalence rates first emerge around puberty." | ( Li, H; Li, J; Li, S; Shao, S; Si, Y; Song, D; Yao, D; Zhang, H; Zhu, Z, 2022) |
| "Depression is a severe mental illness caused by a deficiency of dopamine and serotonin." | ( Ahn, Y; Han, SH; Hong, KB; Jo, K; Kim, MG; Kim, WJ; Suh, HJ, 2021) |
| "Depression is deemed a mood disorder characterized by a high rate of relapse." | ( Hirose, E; Isoda, H; Ito, N; Nagai, T; Odaguchi, H; Sasaki, K, 2022) |
| "Depression is often comorbid in patients with heart failure (HF) and is associated with worse clinical outcomes." | ( Abebe, KZ; Anderson, AM; Herbeck Belnap, B; Jakicic, JM; Karp, JF; Muldoon, MF; Ramani, R; Rollman, BL; Rothenberger, SD, 2021) |
| "Depression is characterised by a heightened self-focus, which is believed to be associated with differences in emotion and reward processing." | ( Button, KS; Hobbs, C; Kessler, D; Munafò, MR; Sui, J, 2023) |
| "Depression is the most frequent affective disorder and is the leading cause of disability worldwide." | ( He, J; Lai, Y; Liu, Q; Qiao, C; Shang, J; Zhang, R; Zhong, H, 2021) |
| "Depression is a prevalent disease worldwide, limiting psychosocial functioning and thequality of life." | ( do Socorro Ferraz Maia, C; Dos Santos, ÉRQ; Fontes-Júnior, EA; Maia, JGS, 2022) |
| "Anxiety and depression are the most common mental health disorders experienced by Australians." | ( Agius, PA; Dietze, P; Duncan, Z; Kippen, R; Quinn, B; Sutton, K; Ward, B, 2022) |
| "Depression is correlated with increased opioid use." | ( Anastasio, AT; Bradbury, TL; Farley, KX; Kurkis, G; Wilson, JM, 2021) |
| "Depression is associated with taste disorders; however, the mechanisms by which mental stress affects taste perception are not well understood." | ( Miyazaki, M; Toyoda, A; Yajima, Y; Yoshida, Y, 2021) |
| "Depression is a primary public health problem." | ( Cui, YL; Qiao, T; Wang, QS; Wang, Y; Xu, D, 2021) |
| "Depression is a kind of common mental disorder associated with neuroinflammation, and astrocytes play a vital role in regulating and mediating neuroinflammation in central nervous system." | ( Feng, B; Liu, SB; Lu, L; Qi, JY; Wang, XS; Yang, F; Yang, LK; Yue, J, 2021) |
| "Depression is a severely debilitating psychiatric disorder that influences more than 15% of the population worldwide." | ( Abd Al Haleem, EN; Ahmed, HI; El-Naga, RN, 2023) |
| "Depression is a prevalent mental disorder." | ( Bian, HT; Liang, L; Wang, GH; Wang, HL; Xiao, L; Xie, YP, 2021) |
| "Depression is a common complication after stroke and is closely related to the poor prognosis of stroke." | ( Ding, C; Gao, L; Guo, M; Wang, X; Xu, M; Xu, W; Yao, J, 2021) |
| "Depression is associated with lower intake of antioxidants and B vitamins." | ( Barreto, SM; Benseñor, IM; Brunoni, AR; da Fonseca, MJM; de Aguiar, OB; Ferriani, LO; Mill, JG; Molina, MDCB; Moreno, AB; Silva, DA; Viana, MC, 2022) |
| "Depression is a common psychopathological state or mood disorder syndrome." | ( Gao, Y; Ling-Hu, T; Liu, SB; Qin, XM; Tian, JS; Wu, WZ; Zhao, YH, 2022) |
| "Depression is one of the strongest predictors of quality of life in patients with Parkinson's disease (PD)." | ( Dong, AQ; Li, D; Liu, CF; Mao, CJ; Ren, C; Wang, CT; Wang, F; Wei, SZ; Yao, XY; Zhang, JB; Zhang, YT, 2021) |
| "Depression is a widespread, withering illness, resulting in a massive personal suffering and economic loss." | ( El-Naga, RN; Gad, AM; Nazeem, M; Wahdan, SA, 2021) |
| "Rats with recurrent depression are highly susceptible to stress and exhibit depression-like behaviours such as weight loss, increased immobility time in tail suspension test, and reduced sucrose preference index." | ( Chen, L; Hong, C; Huang, Z; Kong, W; Qiu, F; Wang, L; Zhang, D; Zhang, G; Zhao, J; Zhong, X, 2021) |
| "Depression is one of the most frequent emotion disorders associated with opiate abstinence, which is thought to be a main cause for relapse." | ( Chai, JR; Chen, YQ; Deng, YZ; Du, JY; Fang, JF; Fang, JQ; Li, QL; Li, XP; Liu, JG; Liu, R; Liu, ZQ; Long, JD; Shao, XM; Sun, X; Wang, Q; Wang, YJ; Yao, SY; Zan, GY, 2021) |
| "anxiety and depression) are commonly observed in patients with epilepsy and induce seizure aggravation." | ( Antunes, GF; Castro, MC; Germann, J; Gomes, GCV; Gouveia, FV; Martinez, RCR; Oliveira, CC; Pinto, TRC; Valle, AC, 2022) |
| "Psychotic depression is a subtype of major depressive disorder characterized by mood congruent hallucinations and/or delusions." | ( Cao, B; Cha, DS; Di Vincenzo, JD; Gill, H; Ho, RC; Le, TT; Lee, Y; Lin, K; Lipsitz, O; Lui, LMW; Mansur, RB; McIntyre, RS; Nasri, F; Rodrigues, NB; Rosenblat, JD; Subramaniapillai, M; Teopiz, KM, 2021) |
| "Depression is a common sequelae of frequent methamphetamine use, and may influence rates of engagement in sexual risk-taking among methamphetamine-using cisgender gay, bisexual, and other men who have sex with men (GBMSM)." | ( Fletcher, JB; Reback, CJ, 2022) |
| "Depression is one of the most prevalent forms of mental disorders and is the most common cause of disability in the Western world." | ( Abdeen, A; Abdel Daim, MM; Behl, T; Bhatia, S; Bungau, S; Ibrahim, SF; Iqbal, MS; Mani, V; Rana, T; Sehgal, A; Sharma, N; Singh, S, 2022) |
| "Iron deficiency and depression are prevalent comorbidities in the setting of heart failure." | ( Bilgrami, NL; Hare, DL; Huang, KW, 2022) |
| "Clinical depression is usually treated in primary care with psychological therapies and antidepressant medication." | ( Attenburrow, MJ; Au-Yeung, SK; Bogacz, R; Browning, M; Chan, F; Cipriani, A; Cleare, A; Cowen, P; Edwards, C; Evans, J; Geddes, J; Griffiths, J; Harmer, CJ; Harrison, PJ; Kessler, D; Lewis, G; Rendell, J; Roberts, S; Shanyinde, M; Simon, J; Singh, I; Watson, S; Yu, LM, 2022) |
| "Depression is highly prevalent and represents the leading cause of global disability and primary contributor to overall global burden of disease." | ( Agin-Liebes, G; Davis, AK, 2022) |
| "Increases in depression are common in some elderly women." | ( Arriaga-Avila, V; Guevara-Guzmán, R; Solís-Ortiz, S; Trejo-Bahena, A, 2021) |
| "Depression is highly comorbid in AN and may be a barrier to recovery." | ( Himmerich, H; Juruena, MF; Kan, C; Keeler, JL; Treasure, J, 2021) |
| "Depression is the leading cause of mental health-related morbidity and affects twice as many women as men." | ( Bastain, TM; Breton, C; Chavez, T; Eckel, SP; Farzan, SF; Grubbs, B; Habre, R; Hernandez-Castro, I; Lagomasino, I; Lerner, D; Lurmann, F; Lurvey, N; Toledo-Corral, CM, 2021) |
| "Depression is a group of syndromes characterized by notable and persistent mood disorders, and is one of the most prevalent psychiatric disorders, while the existing treatments have an altered risk-benefit balance." | ( Badre, L; Filali, H; Jouti, NT; Kadil, Y; Tabyaoui, I, 2022) |
| "Depression is a mental and emotional disorder that has made an opening great burden to the society." | ( Chen, M; Li, Q; Tang, M, 2021) |
| "Depression is a common but serious mental disorder and can be caused by the side effects of medications." | ( Jiang, Y; Li, WP; Liu, J; Liu, JY; Peng, FH; Su, XH; Wang, YJ, 2022) |
| "Anxiety and depression are linked to both explicit and implicit memory biases, which are defined as the tendency to preferentially recall emotionally negative information at conscious and subconscious levels, respectively." | ( Hakamata, Y; Hanakawa, T; Hori, H; Inoue, Y; Izawa, S; Marusak, H; Mihara, K; Mizukami, S; Moriguchi, Y; Okamura, H; Tagaya, H, 2022) |
| "Depression is one of the most common mental illnesses in modern society." | ( Chen, M; Chen, Y; Cheng, Y; Du, H; Li, Y; Mei, J; Wu, W; Zhang, C; Zhao, Z; Zhou, Y; Zhou, Z, 2022) |
| "Depression is one of the common psychiatric disorders during elderly." | ( Abiri, B; Amini, S; Jafarirad, S, 2023) |
| "Depression is a psychiatric disorder that affects about 10% of the world's population and is accompanied by anxiety." | ( Asahi, S; Hori, K; Kanno, Y; Maruyama, C; Matsuo, O; Ozaki, KI; Teramura, H; Tsuchida, K, 2022) |
| "Depression is one of the most common mental disorders." | ( Bogudzińska, B; Kaczmarek, B; Kowalski, K; Piotrowski, P, 2021) |
| "Depression is twice as prevalent in women compared to men, which suggests that biological sex also contributes to depression susceptibility." | ( Barron, A; Harris, EP; McGovern, AJ; Melo, TG; Nolan, YM; O'Leary, OF, 2022) |
| "Depression is a common psychiatric disorder in patients with epilepsy." | ( Baniya, GC; Verma, K, 2022) |
| "Anxiety and depression are complications in Irritable bowel syndrome (IBS) patients." | ( Chen, J; Chen, P; Chen, Y; Guo, Q; He, J; Lin, H; Lin, L; Tan, S; Wen, J; Wen, Z, 2021) |
| "Treating major depression is a medical need that remains unmet by monoaminergic therapeutic strategies that commonly fail to achieve symptom remission." | ( Gould, TD; Hess, EM; Michaelides, M; Riggs, LM, 2022) |
| "Depression is a mood disorder with a high prevalence rate globally, which is associated with abnormalities in 5-hydroxytryptamine (5-HT) metabolism." | ( Chen, C; Chen, S; Farzi, A; Gao, K; Ke, X; Li, Y; Wang, H; Yu, T; Yu, Y, 2022) |
| "Depression is a multifactorial disorder that affects millions of people worldwide, and none of the currently available therapeutics can completely cure it." | ( Kaczor, AA; Matosiuk, D; Stępnicki, P; Zięba, A, 2021) |
| "Depression is often associated with memory impairment, a clinical feature of Alzheimer's disease (AD), but no effective treatment is available." | ( Alves, D; Becker, NP; Biondi, JV; Blodorn, E; Campos, VF; da C Rodrigues, K; de Oliveira, RL; Domingues, WB; Larroza, A; Luchese, C; Pinz, MP; Voss, GT; Wilhelm, EA, 2022) |
| "Depression is a severe psychiatric disorder with oxidative imbalance and neurotrophic deficits as underlying mechanisms." | ( Cysne Filho, FMS; de Almeida Cysne, JC; de Aquino, GA; de Sousa, CNS; Macêdo, DS; Medeiros, IDS; Vasconcelos, GS; Vasconcelos, SMM, 2022) |
| "Depression is a risk factor for Alzheimer's (AD) and cardiovascular diseases (CVD)." | ( Aboutaleb, AS; Abu-Elfotuh, K; Al-Najjar, AH; Badawi, GA; Mohammed, AA, 2022) |
| "Depression is a commonly cited adverse effect of β-blockers but the evidence for a causal relationship is limited." | ( Bornand, D; Jick, SS; Meier, CR; Reinau, D, 2022) |
| "Depression is a chronic, recurrent and life-threatening disease affecting approximately 15% of the world population." | ( Gormus, ZIS; Gunes, CE; Koca, RO; Kutlu, S; Solak, H, 2022) |
| "Depression is a global disease that affects the physical and mental health of people of all ages." | ( Cassilhas, RC; de Oliveira, LRS; De Sousa, RAL; E Magalhães, COD; Machado, FSM; Rocha-Dias, I, 2022) |
| "Depression is a psychiatric disorder characterized by low-esteem, anhedonia, social deficit, and lack of interest." | ( Akhtar, A; Joshi, A; Kuhad, A; Sah, SP; Saroj, P, 2022) |
| "Depression is one of the most common mental illnesses worldwide." | ( Amini-Khoei, H; Bijad, E; Lorigooini, Z; Maghsoudi, F; Moradi, M; Nasiri Boroujeni, S; Rahimi-Madiseh, M, 2022) |
| "Major depression is a leading contributor to the global burden of disease." | ( Becker, G; Bochi, GV; Camargo, LFM; da Silva Carlotto, M; Dos Santos, BM; Fialho, MFP; Oliveira, SM; Pereira, GC; Pillat, MM; Piton, E; Ramanzini, LG; Trevisan, G; Zanchet, EM, 2022) |
| "Depression is very common after stroke, causing multiple sequelae." | ( Feng, RF; Guo, L; Ji, X; Jiao, JW; Li, MM; Ma, R; Wang, P; Zhang, ZX, 2022) |
| "Depression is one of the most common comorbidities of type 2 diabetes." | ( Demers, É; Guénette, L; Lunghi, C; Tardif, I; Zongo, A, 2022) |
| "Depression is a common and recurrent mental illness with a complicated etiology, but the specific pathogenesis is not clear." | ( Bi, Z; Cheng, H; Fan, X; Li, W; Tang, L; Yao, S; Yu, S; Zhang, X, 2022) |
| "Anxiety and depression are frequent among patients with breast cancer (BCa)." | ( Araújo, N; Ferreira, A; Fontes, F; Lopes, C; Lopes-Conceição, L; Lunet, N; Pereira, S, 2022) |
| "Depression is a common psychiatric disorder, which seriously affects people's health and quality of life." | ( Bian, H; Ji, X; Li, W; Tu, W; Yan, F, 2022) |
| "The pathogenesis of depression is greatly affected by glutamatergic neurotransmission dysfunction." | ( Bhatia, NY; Doshi, GM; Kale, PP; Ved, HS, 2022) |
| "Anxiety and depression are associated with suboptimal outcomes, higher complications, and cost of care after elective spine surgery." | ( Boakye, M; Drazin, D; Jain, N; Sharma, M; Ugiliweneza, B; Wang, D, 2022) |
| "Anxiety and depression are often comorbid with tobacco dependence, partly reflecting attempts to self-medicate symptoms with nicotine." | ( Andreasen, JT, 2022) |
| "Depression is a common illness with no definite treatment." | ( Al-Shafei, AI; Daoud, NN; El-Gendy, OA; Zaazaa, AM, 2022) |
| "Depression is associated with total cholesterol, low-density lipoprotein cholesterol, triglycerides, and high-density lipoprotein cholesterol levels in the blood." | ( Han, AL, 2022) |
| "Depression is identified as one of the most common psychiatric symptoms in Alzheimer's disease (AD)." | ( Huang, J; Huang, Y; Li, J; Li, W; Li, X; Sun, A; Wang, L; Wang, W; Xu, Y; Zhang, C; Zhang, H; Zhu, J, 2022) |
| "Depression is a frequent mood disorder that might impair the brain-gut axis." | ( Abedpoor, N; Hajibabaie, F; Taghian, F, 2022) |
| "Depression is a common neuropsychiatric disorder characterized by persistent depressed mood and causes serious socioeconomic burden worldwide." | ( Gao, F; Wang, J; Yang, S; Zhu, G, 2022) |
| "Depression is the most known complication of type 2 diabetes mellitus (T2DM)." | ( Fang, Y; Gu, X; He, Z; Hu, X; Jin, L; Liu, F; Ma, J; Sun, D; Wang, L; Wu, W; Yang, Q; Zhang, X, 2022) |
| "Depression is the most common mental illness." | ( Du, ZJ; Gao, TM; Huang, L; Jin, SY; Li, X; Lin, S; Liu, XW; Luo, ZC; Luo, ZY; Ma, RJ; Ren, CR; Song, YL; Wang, ML; Wang, Q; Wu, DY; Xiong, WC; Yang, JM, 2022) |
| "Depression is a very prevalent and complex disease." | ( Correia, AS; Fraga, S; Teixeira, JP; Vale, N, 2022) |
| "Depression is the most common mental illness, affecting approximately 350 million people around the world." | ( Śliwiński, T; Wigner, P, 2022) |
| "Depression is a serious physical and mental disease, with major depressive disorder (MDD) being a hard-to-treat, life-threatening form of the condition." | ( Gu, T; Jiang, G; Liu, Q; Liu, S; Wang, Y; Yin, A; Zhang, L, 2022) |
| "Depression is a very prevalent psychiatric disorder which threats nearly one in six of the population in this world." | ( Chen, YM; Fan, H; Huang, J; Jiang, B; Li, WY; Liu, JF; Shi, TS; Wang, CN, 2022) |
| "The category of depression is very broad and overinclusive in terms of etiology, the role of psychosocial adversities severity, episodicity, presentation, and relationship with bipolarity." | ( Masi, G, 2022) |
| "Depression is a heterogeneous condition in terms of etiology, the role of psychosocial adversities severity, episodicity, presentation, and relationship with bipolarity." | ( Masi, G, 2022) |
| "Depression is a disease that affects millions of people worldwide, and the discovery and development of effective and safe antidepressant drugs is one of the important topics of psychopharmacology." | ( Can, ÖD; Evren, AE; Kandemir, Ü; Turan Yücel, N, 2022) |
| "Depression is accompanied by circadian regulation disruption and interaction with the functioning of both central and peripheral oscillators." | ( Baig, AA; Bardhan, M; Bhutra, P; Boiko, DI; Chopra, H; Hasan, MM; Kazmi, SK; Shkodina, AD; Skrypnikov, AM, 2022) |
| "Depression is a common manifestation in Alzheimer's disease (AD)." | ( de la Guía, P; García-Alberca, JM; Gris, E; Mendoza, S, 2022) |
| "Depression is a highly prevalent, debilitating mental disorder." | ( Bosch, K; Burattini, I; Calabrese, F; Henckens, MJAG; Homberg, JR; Nieuwenhuis, D; Sbrini, G; Schubert, D, 2022) |
| "Depression is common among primary care patients in LMIC but treatments are largely ineffective." | ( Ekstrand, ML; Heylen, E; Johnson Pradeep, R; Mony, PK; Srinivasan, K, 2022) |
| "Depression is highly prevalent in those diagnosed with cancer and is also associated with poorer prognostic outcomes." | ( Hunter, RL; Marinovic, DA, 2022) |
| "Depression is a psychiatric disorder with limited therapy options." | ( Amariz, IA; Brys, I; Damasceno, TA; Duarte-Filho, LAMS; Massaranduba, ABR; Menezes, PMN; Nishimura, RHV; Ribeiro, LAA; Rolim, LA; Silva, FS, 2022) |
| "Depression is a common mental disease that can lead to suicide when severe." | ( Chen, J; Dong, Y; Feng, C; Li, G; Li, H; Ma, H; Ma, Y; Ren, Y; Wang, Z; Yao, D; Zhou, J; Zhu, Z, 2022) |
| "However, depression is twice as common in women than in men, and it remains unclear whether OT exerts antidepressant-like effects in women with depression." | ( Enjoji, M; Harada, H; Mori, M; Murata, Y; Ohe, K; Shizunaga, H; Tajiri, Y; Terada, K, 2022) |
| "Depression is a common psychiatric symptom in numerous neurological disorders." | ( Hashimoto, K; Wang, X; Yang, J, 2022) |
| "Depression is a common and serious health issue affecting around 280 million people around the world." | ( Daglia, M; Di Minno, A; Khan, A; Rengasamy, KRR; Sacchi, R; Ullah, H, 2022) |
| "Depression is a serious public-health issue." | ( Chen, X; Dong, C; Guo, T; Li, S; Liu, X; Miao, Y; Ren, T; Ruan, H; Sun, M; Wang, B; Wang, J; Wu, Q; Xin, N; Xu, X; Yang, Y; Yuan, Y; Zhang, HG; Zheng, H; Zuo, Y, 2022) |
| "Depression is a major public health challenge linked with several poor health outcomes and disabilities among adults aged 45 years and older in India." | ( Dandona, R; Gudekar, D; Perianayagam, A; Prina, M; Salvi, S; Selvamani, Y; Varghese, M, 2022) |
| "Depression is a major health problem linked to alcohol consumption; it might also be associated with the alcohol flushing response." | ( Cho, I; Cho, SI; Jeon, S; Kang, H, 2022) |
| "Depression is a global health problem, and there is a pressing need for a better understanding of its pathogenesis." | ( Du, Y; Gao, Y; Gong, M; Guo, X; Hao, Y; Shi, H; Shi, M; Shi, Y; Song, H; Song, L; Wang, S; Wang, X; Zhao, Y, 2022) |
| "Late-life depression is frequently underdiagnosed and undertreated." | ( Clifton, J; Littenberg, B; Mason, H; MIller, A; Natkin, L; Tarleton, E, 2022) |
| "Depression is a common disorder that affects patients' quality of life and incurs health system costs." | ( Shamabadi, A, 2022) |
| "Postpartum depression is a common mental disease in obstetric puerperium." | ( Gong, A; Wu, Z; Zeng, M, 2022) |
| "Depression is common at the end of life, and there is longstanding concern that it may affect terminally ill patients' decisions to request physician-assisted death (PAD)." | ( Berens, N; Kim, SY, 2022) |
| "Depression is the most common mental problem among the elderly, especially in long-term care facilities." | ( Chen, PY; Lo, SF; Lu, SF; Yu, AL, 2022) |
| "Depression is a common and serious disorder, characterized by symptoms like anhedonia, lack of energy, sad mood, low appetite, and sleep disturbances." | ( Correia, AS; Vale, N, 2022) |
| "Depression is a high-incidence mental illness that seriously affects human health." | ( Chen, ZZ; Gu, XH; Liu, X; Wang, W; Wu, HJ; Xu, LJ; Yang, G; Yang, YJ; Zheng, LL, 2022) |
| "Depression is a complex neuropsychiatric disease with extensive morbidity." | ( Cai, T; Hu, H; Shi, X; Wang, F; Xiao, SL; Yuan, LZ; Zheng, SP; Zhou, B, 2022) |
| "Pharmacotherapy of depression is characterized by the delayed onset of action, chronic treatment requirements, and insufficient effectiveness." | ( Krupa, AJ; Pochwat, B; Siwek, M; Szewczyk, B, 2022) |
| "Depression is common in people with HIV (PWH), yet little is known about the mechanisms contributing to depressive symptoms in PWH." | ( Cohen, RA; Murphy, AJ; Porges, EC; Rubin, LH; Shortell, DD, 2022) |
| "Depression is a prevalent psychiatric disorder with a significant health impact and economic burden worldwide." | ( Bian, H; Liang, L; Slevin, M; Tu, WJ; Wang, G; Wang, H; Xiao, L; Xie, Y, 2022) |
| "Depression is one of the most prevalent mental disorders associated with reductions in bone mineral density and increased fracture risk." | ( Chua, AN; Ho, CS; Ho, RC; Kumarsing, RA; Lam, RW; McIntyre, RS; Wong, HK, 2022) |
| "Perinatal depression is a common and disabling mental health problem in Malawi and other Low- and middle-income countries." | ( Atif, N; Chirwa, E; Meltzer-Brody, S; Ng'oma, M; Stewart, RC, 2022) |
| "Depression is highly prevalent in patients suffering from chronic inflammatory diseases." | ( Fan, B; Li, S; Liu, X; Lu, C; Tong, L; Wang, F; Wang, Y; Wei, Z, 2022) |
| "Depression is one of the most common complications in patients with diabetes." | ( Hu, Z; Liao, Y; Liu, Y; Shu, L; Wang, J, 2023) |
| "Depression is a mental disease involving complex pathophysiological mechanisms, and there are many ways to establish depressive mouse models." | ( Dong, Y; Liu, L; Liu, S; Yao, H; Yu, X; Zhang, X, 2022) |
| "Major Depression is the leading cause of disability worldwide." | ( Kang, MJY; Vazquez, GH, 2022) |
| "Depression is disabling and highly prevalent." | ( Abdallah, CG; Ballard, ED; Baumeister, A; Blier, P; Charney, DS; Chen, MH; Deakin, W; Fava, M; Feder, A; Gallagher, B; Grunebaum, MF; Hock, R; Kissel, N; Lundberg, J; Mann, JJ; Mathew, SJ; McLoughlin, DM; McMillan, R; Murrough, JW; Muthukumaraswamy, S; Papakostas, G; Phillips, JL; Price, RB; Rohac, R; Shiroma, P; Šóš, P; Su, TP; Sumner, R; Tiger, M; Wallace, ML; Wilkinson, ST; Woody, ML; Zarate, CA, 2022) |
| "Depression is one of the most important and serious health problems in developing countries which affects millions of people." | ( Guclu, E; Inan, SY; Vural, HC, 2022) |
| "The therapy of depression is prevalently based on monoamine reuptake blockers; consequently, investigations aimed to clarify the aetiology of depression have mostly looked at brain areas innervated by monamines and brain circuitry involved in inputs and outputs of these areas." | ( Carboni, E; Carta, AR, 2022) |
| "Schizophrenia and depression are heterogeneous disorders." | ( Biała, G; Mikulska, J; Orzelska-Górka, J; Wiszniewska, A, 2022) |
| "Depression is a common mental disorder that occurs all over the world with treatment resistance commonly seen in clinical practice." | ( Cubała, WJ; Gruchała-Niedoszytko, M; Małgorzewicz, S; Mechlińska, A; Włodarczyk, A, 2022) |
| "Depression is a devastating mood disorder affecting more than 300 million people worldwide." | ( Jafari, A; Khakpour-Taleghani, B; Mirbolouk, B; Rohampour, K; Rostampour, M, 2023) |
| "Depression is one of the most common neuropsychiatric disorders that is characterized by low mood, lack of motivation, slow thinking, and recurrent suicidal thoughts." | ( Chen, W; Du, R; He, Z; Li, J; Pei, H; Zeng, J; Zhao, Y; Zong, Y, 2023) |
| "Depression is a serious mood disorder, and crocetin has a variety of pharmacological activities, including antidepressant effect." | ( Chen, S; Chen, Z; Li, Q; Lin, S; Tao, Y; Tong, Y; Wang, P; Wang, T; Xu, Z, 2022) |
| "Depression is a typical outcome of the repair of posttraumatic stress disorder (PTSD)." | ( Chen, X; Li, X; Wang, Y; Zhang, H; Zhao, R, 2023) |
| "Depression is the most common mental disorder, affecting about 3." | ( Wu, Y; Yu, C; Zhang, H; Zhao, X, 2023) |
| "Depression is the most common mental disorder among people living with HIV/AIDS and has a negative impact on HIV treatment outcomes." | ( Cournos, F; Duarte, CS; Greene, MC; Kokonya, D; Mandlate, F; Mello, MF; Oquendo, MA; Pereira, LF; Sevene, E; Sidat, M; Sweetland, AC; Wainberg, ML, 2022) |
| "Major symptoms of depression are commonly observed in patients requiring total hip arthroplasty (THA), and this is associated with increased pain scores and opioid consumption." | ( Cao, J; Ding, ZC; Huang, C; Li, H; Wang, HY; Yuan, MC; Zhou, ZK, 2023) |
| "Depression is the most common psychiatric disorder." | ( Dashti, S; Nahavandi, A, 2022) |
| "Anxiety, Depression are common among our chronic kidney disease patients, more interventions are needed to improve the mental health of our patients and their quality of life perception." | ( Abdelghani, M; Abu-Hussein, B; Al-Asa'd, Y; Alhawari, H; Alhouri, A; Alshelleh, S; Alwreikat, F; Badran, M; Oweis, AO; Taifour, A, 2022) |
| "Depression is a neuropsychiatric disease that threatens the physical and mental health of humans worldwide." | ( Fan, D; Huang, R; Ma, P; Ma, X; Qu, L; Shao, J, 2023) |
| "Depression is one of the most important mental illnesses and is closely related to inflammation." | ( Meng, LQ; Peng, XD; Quan, HF; Shi, H; Wang, XL; Yan, L; Yang, HF; Zhang, M, 2022) |
| "Depression is a well-known serious mental illness, and the onset of treatment using traditional antidepressants is frequently delayed by several weeks." | ( Hashimoto, K; Yao, Y; Zhang, K, 2023) |
| "Depression is a common disorder with a complex pathogenesis." | ( Chen, LL; Lin, L; Liu, SZ; Wang, P; Yang, J, 2023) |
| "Depression is a common disorder with a complex pathogenesis." | ( Chen, LL; Lin, L; Liu, SZ; Wang, P; Yang, J, 2023) |
| "Depression is a common disorder with a complex pathogenesis." | ( Chen, LL; Lin, L; Liu, SZ; Wang, P; Yang, J, 2023) |
| "Depression is a serious mental illness, mainly characterized as large mood swings and sleep, diet, and cognitive function disorders." | ( Cheng, WJ; Gao, YH; Li, CF; Liu, YJ; Wang, Y; Xu, GH; Ye, ZW; Yi, LT; Yuan, ZY; Zhang, MM; Zhou, H, 2022) |
| "Depression is a serious mental illness, mainly characterized as large mood swings and sleep, diet, and cognitive function disorders." | ( Cheng, WJ; Gao, YH; Li, CF; Liu, YJ; Wang, Y; Xu, GH; Ye, ZW; Yi, LT; Yuan, ZY; Zhang, MM; Zhou, H, 2022) |
| "Depression is a serious mental illness, mainly characterized as large mood swings and sleep, diet, and cognitive function disorders." | ( Cheng, WJ; Gao, YH; Li, CF; Liu, YJ; Wang, Y; Xu, GH; Ye, ZW; Yi, LT; Yuan, ZY; Zhang, MM; Zhou, H, 2022) |
| "Depression is positively correlated with the high incidence and low survival rate of cancers, while more cancer patients suffer depression." | ( Li, KW; Liu, BP; Song, C; Zhang, C; Zhang, YP, 2022) |
| "Depression is positively correlated with the high incidence and low survival rate of cancers, while more cancer patients suffer depression." | ( Li, KW; Liu, BP; Song, C; Zhang, C; Zhang, YP, 2022) |
| "Depression is positively correlated with the high incidence and low survival rate of cancers, while more cancer patients suffer depression." | ( Li, KW; Liu, BP; Song, C; Zhang, C; Zhang, YP, 2022) |
| "Depression is one of the most common psychiatric diseases worldwide." | ( Chen, J; Jia, Y; Lin, C; Liu, X; Wang, S; Yu, X, 2023) |
| "Depression is one of the most common psychiatric diseases worldwide." | ( Chen, J; Jia, Y; Lin, C; Liu, X; Wang, S; Yu, X, 2023) |
| "Depression is one of the most common psychiatric diseases worldwide." | ( Chen, J; Jia, Y; Lin, C; Liu, X; Wang, S; Yu, X, 2023) |
| "Depression is one of the most common diseases in the older population." | ( Chrzastek, Z; Guligowska, A; Kostka, T; Sobczuk, P, 2023) |
| "Depression is one of the most common diseases in the older population." | ( Chrzastek, Z; Guligowska, A; Kostka, T; Sobczuk, P, 2023) |
| "Depression is one of the most common diseases in the older population." | ( Chrzastek, Z; Guligowska, A; Kostka, T; Sobczuk, P, 2023) |
| "Depression is one of the most common mental disorders which dramatically threatens public health and wellness." | ( Hongrong, W; Jianfeng, Z; Kaifang, Z; Qingqi, L; Rong, G; Shuangyang, T, 2023) |
| "Depression is one of the most common mental disorders which dramatically threatens public health and wellness." | ( Hongrong, W; Jianfeng, Z; Kaifang, Z; Qingqi, L; Rong, G; Shuangyang, T, 2023) |
| "Depression is one of the most common mental disorders which dramatically threatens public health and wellness." | ( Hongrong, W; Jianfeng, Z; Kaifang, Z; Qingqi, L; Rong, G; Shuangyang, T, 2023) |
| "Depression is the most common comorbidities associated with rheumatoid arthritis (RA)." | ( Bao, Y; Huang, X; Jin, Y; Lin, F; Lu, L; Ma, Y; Ren, H; Tan, L; Wang, F; Wu, L; Xie, X; Zhang, Y, 2023) |
| "Depression is the most common comorbidities associated with rheumatoid arthritis (RA)." | ( Bao, Y; Huang, X; Jin, Y; Lin, F; Lu, L; Ma, Y; Ren, H; Tan, L; Wang, F; Wu, L; Xie, X; Zhang, Y, 2023) |
| "Depression is frequent among older adults and is a risk factor for dementia." | ( Assunção, N; De Felice, FG; Drummond, C; Ferreira, DDP; Ferreira, ST; Gonçalves, RA; Lourenco, MV; Mattos, P; Pamplona, FA; Ribeiro, FC; Sudo, FK; Tovar-Moll, F; Vanderborght, B, 2023) |
| "Depression is frequent among older adults and is a risk factor for dementia." | ( Assunção, N; De Felice, FG; Drummond, C; Ferreira, DDP; Ferreira, ST; Gonçalves, RA; Lourenco, MV; Mattos, P; Pamplona, FA; Ribeiro, FC; Sudo, FK; Tovar-Moll, F; Vanderborght, B, 2023) |
| "Depression is a psychiatric disease which is accompanied by metabolic disorder." | ( Bian, X; Fang, Y; Li, N; Li, Y; Wang, X; Wu, JL; Zhang, X; Zhao, Y; Zhou, N; Zhou, T, 2023) |
| "Depression is a psychiatric disease which is accompanied by metabolic disorder." | ( Bian, X; Fang, Y; Li, N; Li, Y; Wang, X; Wu, JL; Zhang, X; Zhao, Y; Zhou, N; Zhou, T, 2023) |
| "Postpsychotic depression is challenging to differentiate, yet it is clinically frequent, puts patients at risk for suicide, and affects their mental capacity." | ( Kocha, H; Nakagawa, A; Oguchi, Y, 2023) |
| "Postpsychotic depression is challenging to differentiate, yet it is clinically frequent, puts patients at risk for suicide, and affects their mental capacity." | ( Kocha, H; Nakagawa, A; Oguchi, Y, 2023) |
| "Treatment-resistant depression is a pleomorphic phenomenon occurring in 30% of patients with depression." | ( Cubała, WJ; Wilkowska, A, 2022) |
| "Treatment-resistant depression is a pleomorphic phenomenon occurring in 30% of patients with depression." | ( Cubała, WJ; Wilkowska, A, 2022) |
| "Depression is the most prevalent and devastating neuropsychiatric disorder." | ( Albarrati, A; Albratty, M; Behl, T; Bungau, SG; Makeen, HA; Najmi, A; Rana, T; Sehgal, A; Sharma, N; Verma, R, 2023) |
| "Depression is the most prevalent and devastating neuropsychiatric disorder." | ( Albarrati, A; Albratty, M; Behl, T; Bungau, SG; Makeen, HA; Najmi, A; Rana, T; Sehgal, A; Sharma, N; Verma, R, 2023) |
| "Depression is a chronic recurrent neuropsychiatric disorder associated with inflammation." | ( Ahmad, FU; Arshad, HM; Lodhi, AH, 2022) |
| "Depression is a chronic recurrent neuropsychiatric disorder associated with inflammation." | ( Ahmad, FU; Arshad, HM; Lodhi, AH, 2022) |
| "It is found that depressionis a risk factor for dementia, just as dementia is a risk factor for depression." | ( Guligowska, A; Kostka, T; Pawlikowski, M; Piechocka-Wochniak, E; Pisarek, H; Świętosławski, J; Winczyk, K, 2022) |
| "It is found that depressionis a risk factor for dementia, just as dementia is a risk factor for depression." | ( Guligowska, A; Kostka, T; Pawlikowski, M; Piechocka-Wochniak, E; Pisarek, H; Świętosławski, J; Winczyk, K, 2022) |
| "Depression is a very common mental disorder and mechanism that is associated with mitochondrial dysfunction." | ( Bagheri, A; Motafeghi, F; Seyedabadi, M; Shaki, F; Shokrzadeh, M, 2022) |
| "Depression is a very common mental disorder and mechanism that is associated with mitochondrial dysfunction." | ( Bagheri, A; Motafeghi, F; Seyedabadi, M; Shaki, F; Shokrzadeh, M, 2022) |
| "Depression is a mental health problem and substance use concerns are socially unacceptable behaviors." | ( Chang, CW; Chang, KC; Chen, IH; Chen, JS; Huang, SW; Lin, CY; Liu, CH; Potenza, MN; Saffari, M, 2022) |
| "Depression is one of the most prevalent mental diseases characterized by distortions in the affective sphere." | ( Guo, X; Li, S; Liu, S; Liu, Z, 2022) |
| "Depression is one of the leading health problems, and >300 million people have a major depressive disorder and this number is getting increasing." | ( Ekinci, GN; Sanlier, N, 2023) |
| "Although depression is categorized as a brain disorder, its symptomatology includes some behaviors that also occur during chronic inflammatory stress." | ( Aydin, A; Mat, AF; Ozhan, Y; Sipahi, H, 2023) |
| "Depression is a prevalent and recurrent psychiatric disorder." | ( Meng, X; Miao, C; Su, Y; Wang, XL; Zhang, C, 2023) |
| "Depression is characterized by deficits in the positive valence systems (PVS), which also decline with age." | ( Alexopoulos, GS; Arader, L; Areán, PA; Bress, JN; Gunning, FM, 2023) |
| "Depression is a psychiatric disorder leading to anhedonia and lack of interest and motivation." | ( Alhalmi, A; Kumar, G; Pathak, D; Sharma, A; Singh, T; Virmani, T, 2022) |
| "Depression is associated or correlated with increased toxicity and severity of physical symptoms." | ( Chen, J; Hu, R; Li, C; Li, J; Qiao, H, 2023) |
| "Depression is a common complication after myocardial infarction (MI) that can seriously affect the prognosis of MI." | ( Cheng, Y; Huang, T; Huang, Z; Li, X; Liu, Z; Shi, S; Tian, X; Yang, Y; Zhang, H; Zhang, R, 2023) |
| "Depression is a serious public health problem today, especially in middle-aged and older adults." | ( Cheng, J; Jin, X; Li, Y; Liang, Y; Mei, L; Pan, R; Qin, W; Song, J; Su, H; Sun, X; Wu, Q; Wu, Y; Yan, S; Yi, W, 2023) |
| "Depression is the second leading cause of disability in the world population, for which currently available pharmacological therapies either have poor efficacy or have some adverse effects." | ( Asim, M; Wang, H; Waris, A, 2023) |
| "Depression is the most prevalent psychiatric disease, and its pathogenesis is still unclear." | ( Ding, T; Guan, Z; Jia, S; Wang, R; Zhang, D; Zhang, J; Zhao, X, 2023) |
| "Adolescent depression is associated with both dysfunction in neural reward processing and peripheral inflammatory markers (PIMs), such as interleukin-6 (IL-6), C-reactive-protein (CRP), and tumor-necrosis factor alpha (TNFα)." | ( Eckstrand, K; Forbes, E; Nance, M; Rengasamy, M, 2023) |
| "Depression is a serious and widespread mental health disorder." | ( Correia, DT; Dos Santos, IB; Dourado, A; Florez, ID; Fontes-Mota, GCH; Fráguas, R; Gabriel, FC; Melo, DO; Ribeiro, E; Rodrigues, CDS; Rodrigues, MC; Stein, AT, 2023) |
| "Major depression is a risk factor for sexual problems, and improvement in sexual function was coupled with amelioration of depressive symptoms." | ( Armand, S; Frokjaer, VG; Giraldi, A; Joergensen, MB; Knudsen, GM; Nielsen, JH; Stenbaek, DS; Weber, S, 2023) |
| "Depression is a leading cause of the global burden of disease and has a multifactorial etiology that includes nutrients." | ( Chou, MH; Lin, CY; Lin, SH; Wang, JD; Yang, YK, 2023) |
| "Depression is inadequately recognized and managed, and physicians' attitudes toward this condition and its treatment may play a part in this." | ( Agolli, A; Alvarado-Villa, GE; Camacho L, G; Cherrez Ojeda, I; Cherrez, M; Espinoza-Fuentes, F; Farfán Bajaña, MJ; Felix, M; Maquilón, JR; Mautong, H; Michel, J; Orellana Román, C; Sarfraz, A; Sarfraz, Z; Valdevilla Figueira, JA; Vanegas, E, 2023) |
| "Depression is closely associated with reduced norepinephrine (NE) levels; therefore, developing bioimaging probes to visualize NE levels in the brain is a key to elucidating the pathophysiological process of depression." | ( He, Z; Hua, J; Qiu, Z; Wen, C; Zhang, C; Zhao, S, 2023) |
| "Depression is a mental health disorder that develops as a result of complex psycho-neuro-immuno-endocrinological disturbances." | ( Dobrek, L; Głowacka, K, 2023) |
| "Depression is associated with intestinal dysbiosis." | ( Huang, F; Shen, W; Shi, H; Tao, Y; Wu, H; Wu, X; Zheng, F; Zhou, H, 2023) |
| "Depression is a common psychiatric health issue affecting an estimated 5% of adults worldwide, and it can lead to disability and increased economic burden." | ( Chen, SC; Geng, JH; Lee, JI; Tseng, H, 2023) |
| "Depression is highly comorbid with metabolic disorders, but a mechanistic link is elusive." | ( Menard, C; Paton, SE, 2023) |
| "Depression is one of the most common mood disturbances worldwide." | ( Ao, HQ; Chen, WC; Chen, WG; He, CY; He, SQ; Li, T; Lin, HS; Liu, Y; Song, ML; Sun, HT; Yang, XM; Zhang, MJ; Zhang, Y; Zhong, XD, 2023) |
| "Depression is a common, severe, and debilitating psychiatric disorder of unclear etiology." | ( Chen, G; Cui, M; Dai, J; Li, C; Li, Q; Liu, C; Liu, J; Liu, Y; Ma, X; Meng, F; Wang, D; Wang, W; Wu, M; Xie, J; Zhao, D, 2023) |
| "Depression is a widespread disorder with a significant burden on individuals and society." | ( Elfving, B; Müller, HK; Sanchez, C; Smith, KL; Varastehmoradi, B; Wegener, G, 2023) |
| "Depression is a profound public health concern, yet its etiology remains unclear." | ( Chou, MH; Lin, CY; Lin, SH; Wang, JD; Yang, YK, 2023) |
| "Depression is a common mental disorder with an increasing incidence." | ( Chen, DZ; He, HN; Song, XY; Song, YP; Tuo, LJ; Xu, DX; Zhang, H; Zheng, XM; Zhu, YY, 2023) |
| "Depression is a leading cause of disability worldwide and the psychiatric diagnosis most commonly associated with suicide." | ( Chen, Q; Hu, J; Lan, J; Li, X; Liu, M; Peng, Y; Shang, N; Wang, H; Xiang, L; Xiao, Q; Yin, D, 2023) |
| "Depression is common among people living with HIV (PLWH)." | ( Gaynes, BN; Hosseinipour, MC; Kulisewa, K; Minnick, CE; Mphonda, S; Pence, BW; Sansbury, G; Stockton, MA; Udedi, MM, 2023) |
| "Depression is a common mental disorder that seriously affects the quality of life and leads to an increasing global suicide rate." | ( Li, H; Qing, H; Quan, Z, 2023) |
| "Depression is a common mental health problem in older adults, but its cause remains unclear." | ( He, S; Liu, Y; Wang, L; Wang, Z, 2023) |
| "Depression is a psychiatric disorder and confers an enormous burden on society." | ( Du, X; Gao, Y; Li, X; Li, Y; Liu, S; Wang, D; Xu, Y; Zhang, Y; Zhao, Y, 2023) |
| "Antepartum depression is common, and outside of childbirth preoperative anxiety and depression have been associated with heightened postoperative pain." | ( Gompers, A; Hacker, MR; Sudhof, LS, 2023) |
| "Depression is a multifactorial and heterogeneous disease with several neurobiological mechanisms underlying its pathophysiology, including dysfunctional glutamatergic neurotransmission, which makes the exploration of the glutamate pathway an interesting strategy for developing novel rapid-acting antidepressant treatments." | ( Alves, D; Blödorn, GB; Bortolatto, CF; Brüning, CA; Krüger, LD; Neto, JSS; Rech, TDST; Strelow, DN, 2023) |
| "Depression is a common but severe mood disorder with a very high prevalence across the general population." | ( Dong, X; Zhao, D, 2023) |
| "Depression is the most commonly experienced mood state over the life span in individuals with bipolar disorder (BD) and is the primary driver of functional impairment and suicidality in BD." | ( Chakrabarty, T; DuBois, A; Keramatian, K; Saraf, G; Yatham, LN, 2023) |
| "Depression is a major mental disease worldwide, causing dysfunction of Lateral Habenular (LHb)." | ( Chen, W; Chen, Y; Cheng, W; Gulizhaerkezi, T; Hao, C; Li, J; Li, Y; Meng, X; Shen, J; Tong, T; Yan, S; Zeng, J, 2023) |
| "Depression is the most common psychiatric disorder reported among patients living with Human Immunodeficiency Virus (HIV), resulting from the intricate combination of biological, psychological, and social factors." | ( Abdul Manaf, R; Fattah Azman, AZ; Karpal Singh, GK; Mohamad Fisal, ZA, 2023) |
| "Depression is a common illness in people with HIV (PWH) and is associated with substantial morbidity and mortality." | ( Anderson, AM; Farber, EW; Felger, JC; Franklin, D; Fu, R; Jinnah, H; Letendre, SL; Mckay, JL; Miller, AH; Moore, RC; Sharma, S; Whicker, N, 2023) |
| "Prepartum depression is associated with early adversity, pregnancy complications, preterm delivery, postpartum depression, and long-term effects on child neurodevelopment." | ( Bertoni, B; Fernández, L; Grandi, G; Laporte, G; Medici, F; Musetti, D; Nicolaisen-Sobesky, E; Olazábal, DE; Rey, G; Sandberg, N, 2023) |
| "Chronic pain and depression are common comorbid conditions, but there is limited evidence-based guidance for management of the two conditions together." | ( Cheng, DK; Gage, H; Moineddin, R; Sud, A; Ullah, MH, 2023) |
| "Depression is a high-incidence mood disorder that is frequently accompanied by sleep disturbances, which can be triggered by the non-image-forming (NIF) visual system." | ( Cao, M; Chen, D; Guo, X; Song, Y; Wang, H; Wei, S; Xu, T; Yin, D; Zhang, H, 2023) |
| "Depression is a common and severe mental disorder." | ( Asim, M; Fang, W; Feng, H; Gao, Q; He, J; Kim, K; Lai, Y; Md Monir, H; Wang, H; Wang, S; Zhang, X, 2023) |
| "Late-life depression is associated with substantial heterogeneity in clinical presentation, disability, and response to antidepressant treatment." | ( Conway, C; Elson, D; Kang, H; Sudol, K; Szymkowicz, SM; Taylor, WD, 2023) |
| "Clinical depression is a common, debilitating and heterogenous disorder." | ( Cowen, PJ; Harmer, CJ; Murphy, SE; Smith, ALW, 2023) |
| "Adolescent depression is becoming one of the major public health concerns, because of its increased prevalence and risk of significant functional impairment and suicidality." | ( Fan, Y; Gao, R; Liu, W; Wang, J; Wang, S; Wu, L; Xu, H; Xu, L; Yao, H; Yu, J; Yu, Z; Zhang, J; Zhang, L; Zhou, M, 2023) |
| "Depression is a prevalent mental condition that is challenging to diagnose using conventional techniques." | ( Abd-Alrazaq, A; Ahmed, A; Alsaad, R; Aziz, S; Sheikh, J, 2023) |
| "Depression is a common mental disease, with some patients exhibiting ideas and behaviors such as self-harm and suicide." | ( Gao, F; Guan, H; Li, J; Liang, J; Lu, Z; Teng, F; Tian, X; Wang, J; Wang, X, 2023) |
| "Depression is a multifactorial syndrome with a variety of underlying pathological mechanisms." | ( Cai, J; Fogaça, MV; Li, C; Liu, H; Yuan, H; Zhang, J; Zhang, YW, 2023) |
| "Depression is a clinically common and easily overlooked mental disease." | ( Ge, C; Lei, L; Wang, S; Wu, X, 2023) |
| "Depression is a disabling condition that often leads to significant burden." | ( Soares, CN, 2023) |
| "Depression is common among people with tuberculosis (TB)." | ( Adhikary, A; Afaq, S; Desai, G; Faisal, MR; Huque, R; Jennings, HM; Kanan, S; Khan, I; Nisar, Z; Shree, V; Siddiqi, N; Todowede, O, 2023) |
| "Depression is a common condition found among people with TB, requiring early identification among people with TB." | ( Adhikary, A; Afaq, S; Desai, G; Faisal, MR; Huque, R; Jennings, HM; Kanan, S; Khan, I; Nisar, Z; Shree, V; Siddiqi, N; Todowede, O, 2023) |
| "Depression is a chronic mental disorder which threatens human health and lives." | ( Guan, Q; Liu, T; Lv, L; Wang, X; Yu, S, 2023) |
| "Depression is a mental illness caused by neuroinflammation or changes in neuroplasticity in certain brain regions, such as the prefrontal cortex and hippocampus." | ( Jeon, M; Jung, SY; Kang, WC; Kim, DY; Kim, JY; Kong, CH; Lee, WH; Min, JW; Park, K; Ryu, JH, 2023) |
| "Depression is a serious mood disorder characterized by monoamines deficiency, oxidative stress, neuroinflammation, and cell death." | ( Abdel Rasheed, NO; Ibrahim, WW; Mohamed, SS; Shiha, NA, 2023) |
| "Depression is a common psychiatric disorder affecting around 300 million people worldwide." | ( Hiramatsu, M; Ibi, D; Kinoshita, M; Nakasai, G; Sawahata, M; Takaba, R; Yamada, K, 2023) |
| "Depression is a multifaceted psychiatric disorder that affects a significant number of individuals worldwide, and its pathophysiology encompasses a variety of mechanisms, including the induction of endoplasmic reticulum (ER) stress, which has been correlated with depressive-like behaviors in animal models." | ( Chen, PL; Cheng, J; Li, CF; Li, M; Xu, GH; Yi, LT; Zhang, JY, 2023) |
| "Depression is caused by a variety of factors such as genetic factors, biological factors, and psychosocial factors, and the pathogenesis is complex." | ( He, J; Huang, Y; Li, C; Li, G; Li, H; Miao, C; Peng, Y; Wang, X; Wang, Y; Wu, Y; Xu, P, 2023) |
| "Depression is a common mental health problem among veterans, with high mortality." | ( Duan, Y; Guo, D; He, G; Lan, L; Liu, X; Meng, H; Qu, Z; Sui, C; Wang, Y; Zhang, X, 2023) |
| "Depression is a prevalent mental health disorder with a complex etiology and substantial public health implications." | ( Han, X; Li, Y; Liu, J; Ma, Y; Tian, W; Wang, H; Yan, G; Zhang, Q; Zhang, Y, 2023) |
| "Depression is a profound mental disorder that dampens the mood and undermines volition, which exhibited an increased incidence over the years." | ( Wu, G; Xu, H, 2023) |
| "Depression is a global mental health concern, and personalized treatment approaches are needed to optimize its management." | ( Hadryś, T; Machowska, M; Maciaszek, J; Misiak, B; Pawłowski, T; Wiela-Hojeńska, A, 2023) |
| "Depression is one of the most common psychiatric conditions in dialysis patients and is linked to increased morbidity, mortality, treatment failure, expense, and hospitalization." | ( Erdoğan Kaya, A; Eser, B; Tutan, D, 2023) |
| "In addition, depression is characterized by a decreased functioning of the serotonergic system due to changes in the activity or expression of its receptors including, most significantly, 5-HT1A, 5-HT2A, and 5-HT3 in brain regions that regulate mood, emotions, and memory, such as the prefrontal cortex, hippocampus, and amygdala." | ( Arteaga-Silva, M; Bonilla-Jaime, H; Cerbón, M; Limón-Morales, O; Molina-Jiménez, T; Morales-Quintero, K, 2023) |
| "Pediatric depression is a common psychiatric disorder that is associated with significant morbidity and mortality." | ( Cao, B; Ceban, F; Chisamore, N; Danayan, K; Ho, RC; McIntyre, RS; Meshkat, S; Rhee, TG; Rosenblat, JD; Vincenzo, JDD, 2022) |
| "Anxious depression is a prevalent disease with devastating consequences." | ( Estivill-Torrús, G; Gómez-Salas, FJ; Moreno-Fernández, RD; Nieto-Quero, A; Pedraza, C; Rodríguez de Fonseca, F; Sampedro-Piquero, P; Santín, LJ, 2023) |
| "Depression is a common chronic psychiatric illness, which is resistant to medical treatments." | ( Fang, Y; Hao, J; He, Y; Huang, H; Li, R; Liu, X; Ran, L; Wang, M; Wang, W; Wang, X; Yao, D, 2023) |
| "Depression is one of the most common psychological disorders among multiple sclerosis (MS) patients that characterized as the first symptoms." | ( Aryaeian, N; Delbandi, AA; Farhangnia, P; Hajiluian, G; Heshmati, J; Karegar, SJ; Lotfi, T; Salehi, M; Shidfar, F, 2023) |
| "Depression is a common mental disease, accompanied by anxiety and persistent depression." | ( Ling, Y; Liu, L; Liu, M; Liu, Y; Qiu, Y; Yin, Y; Zhang, Y, 2023) |
| "Depression is a critical and persistent public health problem among-older females in India." | ( Muhammad, T; Paul, R; Rashmi, R; Sharma, P; Srivastava, S; Zanwar, PP, 2023) |
| "Depression is a widespread mental health disorder with complex neurobiological underpinnings." | ( Chen, C; Feng, W; Ning, Y; Wang, M; Xu, Y; Yu, T; Zhang, B, 2024) |
| "Depression is a serious neuropsychiatric disease affecting an increasing number of people worldwide." | ( Czechowska, E; Pańczyszyn-Trzewik, P; Sowa-Kućma, M; Stachowicz, K, 2023) |
| "The pathogenesis of depression is unclear, and it responds poorly to treatment." | ( Fei, D; Gao, C; Hou, Z; Jin, M; Liu, J; Lv, P; Ni, A; Zhai, X; Zhang, S; Zhang, X; Zhou, Y, 2023) |
| "Depression is a type of mental disorder with a significant and persistent low mood as the main clinical feature." | ( Han, Y; Huang, S; Liu, K; Liu, S; Xiong, F, 2023) |
| "Major depression is a common, long-lasting, and recurrent psychiatric disorder with a high suicide rate." | ( Ganesan, K; Gong, G; Liu, Y; Wang, J; Wang, Y; Yang, F; Zhang, Z; Zheng, Y, 2024) |
| "Unipolar depression is one of the most significant biomedical problems, which is associated with its high prevalence, a pronounced negative impact on the level of work capacity of the population, worsening of the course of most somatic and neurological diseases, and suicide risk." | ( Petelin, DS; Volel', BA, 2023) |
| "Depression is a common psychiatric disorder and a leading cause of disability worldwide." | ( Igoe, A; Jelovac, A; Loughran, O; McCaffrey, C; McDonagh, K; McDonogh, S; McLoughlin, DM; Mohamed, E; O'Neill, C; Shackleton, E; Shanahan, E; Terao, M; Whooley, E, 2023) |
| "The pathology of depression is related to the imbalance of various neurotransmitters." | ( Chang, W; Chen, X; Li, W; Shen, Z; Xu, S; Yin, X; Yu, J, 2023) |
| "Depression is on the rise and has become a significant concern for public health." | ( Adnan, MAA; Ahmad, NA; Chan, YM; Khalil, MKN; Lai, WK; Sahril, N; Yoga Ratnam, KK, 2023) |
| "Anemia and depression are common in the elderly and they are important medical, social and economic problems for the world." | ( Michalak, SS; Sterna, W, 2023) |
| Excerpt | Reference |
|---|
| "This article focuses on the treatment of depression with special reference to pharmacotherapy." | ( Denber, HC, 1979) |
| "Trials of treatment of depression--monopolar and bipolar,--involutional,--neurotic and reactive,--in chronic schizophrenia." | ( Kamoun, A, 1979) |
| "Good results have been obtained in the treatment of depression, and obsessive/compulsive/phobic states, and mixed patients." | ( Rack, PH, 1977) |
| "The possibility of tranylcypromine as a treatment for the depression and appropriate counselling of patient and family are discussed." | ( Hendler, N; Leahy, W, 1978) |
| "Two women being treated for depression with fluoxetine developed psoriasis after 6 and 12 months' exposure." | ( Hemlock, C; Rosenthal, JS; Winston, A, 1992) |
| "Tryptophan is effective in the treatment of mild depression and may reduce aggressive behavior." | ( Hilakivi-Clarke, LA, 1991) |
| "The biological treatment of depression includes administration of psychoactive drugs (cyclic antidepressants, MAO-inhibitors, neuroleptics and lithium), use of certain substances which in small amounts are normally present in food such as, L-tryptophan (L-TP) and L-5-hydroxytryptophan (L-5HTP), electroconvulsive therapy (ECT) and various manipulations of the sleep-wake rhythms." | ( Haffmans, J; Nolen, WA, 1989) |
| "Carbamazepine effectively treated the depression and mania was avoided." | ( Finkel, JA; Nurnberg, HG, 1985) |
| "Until recently, all drugs used to treat depression appeared to enhance neurotransmission in one or both of these systems, which was used to explain their antidepressant actions (Gelenberg and Klerman, 1978)." | ( Gelenberg, AJ; Gibson, CJ, 1984) |
| "The use of thyroid hormones in the treatment of depression is reviewed." | ( Joffe, RT; Singer, W; Sokolov, ST, 1995) |
| "Tianeptine is effective in the treatment of depression in elderly and post-alcohol-withdrawal patient subgroups." | ( Benfield, P; Wilde, MI, 1995) |
| "Measures of clinician treatment style for depression are good proxies for counseling but not for prescribing practices." | ( Camp, P; Meredith, LS; Wells, KB, 1994) |
| "The dose regimen for sertraline in the treatment of depression has been well established." | ( Lane, RM; Preskorn, SH, 1995) |
| "Pharmacological treatment of depression in persons with epilepsy has been an area of controversy because some drugs commonly are perceived specifically to induce or exacerbate seizures in patients with seizure disorders." | ( Dailey, JW; Naritoku, DK, 1996) |
| "Finally, treatment of depression in the elderly results in improved quality of life, especially in domains of well being and coping." | ( Reynolds, CF, 1997) |
| "Our ability to treat depression has improved with the availability of receptor-specific and chemically diverse groups of antidepressants." | ( Ananth, J, 1998) |
| "Its efficacy in treating depression was evident in both placebo-controlled and comparator trials." | ( Levin, GM; Tan, JY, 1999) |
| "Direct costs for treating depression, i." | ( Häggström, L; Nordling, S; Norinder, A, 2000) |
| "Antidepressant therapy for treatment of depression is associated with a significantly lower monthly cost of medical care services." | ( Crystal, S; Olfson, M; Sambamoorthi, U; Walkup, J, 2000) |
| "Successful treatment of depression may constitute one of the major methods of promoting cognitive recovery in victims of stroke." | ( Kimura, M; Kosier, JT; Robinson, RG, 2000) |
| "After treatment of depression, a significant increase in SI (10." | ( Hongo, M; Imai, T; Okamura, F; Sato, Y; Suchi, T; Suzuki, S; Tamura, D; Tashiro, A; Utumi, A, 2000) |
| "The identification and treatment of depression should be one of the elements in the rehabilitation of cardiac patients." | ( Hintikka, J; Koukkunen, H; Laakso, M; Lehto, S; Pyörälä, K; Viinamäki, H, 2000) |
| "A continuing challenge in the treatment of depression is how to determine whether an effective drug has been selected for a particular patient, given that individuals will respond to some antidepressants but not others." | ( Cook, IA; Leuchter, AF, 2001) |
| "To determine whether treatment of depression with standard antidepressant medications resulted in reductions in basal activity of afternoon cortisol, ACTH and AVP." | ( Donald, RA; Inder, WJ; Joyce, PR; Mulder, RT; Prickett, TC, 2001) |
| "Early internal treatment of mild depression consists of three factors, rest, antidepressants and psychosocial supports." | ( Kuboki, T, 2001) |
| "Estrogen replacement therapy (ERT) treats mild depression but may not treat more severe depression in this population." | ( Cohen, LS; Groninger, H; Joffe, H; Nonacs, R; Soares, C; Soares, CN, 2001) |
| "Citalopram, a newer SSRI used in the treatment of depression, has not been studied for GAD." | ( Rauscher, F; Varia, I, 2002) |
| "Emphasis is given to the treatment of depression and how the potential of one pure enantiomer-escitalopram, the S-enantiomer of the selective serotonin reuptake inhibitor citalopram-appears to be fulfilling its preclinical promise in the clinic." | ( Baumann, P; Eap, CB; Zullino, DF, 2002) |
| "John's wort as a self-treatment for depression; to review laws regulating the production and sale of herbal products in the United States (U." | ( Boehnlein, B; Oakley, LD, 2002) |
| "John's wort may be an effective treatment for mild depression; however, evidence of significant adverse drug interactions with St." | ( Boehnlein, B; Oakley, LD, 2002) |
| "Helping oncologists to identify and treat depression is an important step in improving the overall care of people with cancer." | ( Donaghy, K; Dugan, W; Edgerton, S; Holtsclaw, E; Kirsh, KL; Passik, SD; Theobald, D, 2002) |
| "John's wort supplement for treatment of depression." | ( Abourashed, EA; Glisson, JK; Hufford, CD; Khan, I; Ogletree, R; Rogers, HE, 2003) |
| "An increasing proportion of elderly treated for depression with antidepressants received the new generation antidepressants." | ( Crystal, S; Olfson, M; Sambamoorthi, U; Walkup, JT, 2003) |
| "This study examined the effects of treatment for depression on social support among patients with multiple sclerosis (MS)." | ( Barrera, M; Classen, C; Mohr, DC, 2004) |
| "The pharmacological approach to the treatment of depression includes a long-term employment of antidepressants, either in the form of monotherapy or as a combination of several antidepressants with various mechanisms of action." | ( Bach-Rojecky, L; Kalodjera, Z; Samarzija, I, 2004) |
| "Preferential treatment of this depression type was discussed." | ( van Praag, HM, 2004) |
| "Prompt treatment of depression has significant favourable effects on mood and quality of life and beneficial effects on glycaemic control among the diabetic patients." | ( Chowdhury, S, 2004) |
| "The burden of not treating depression effectively to remission is significant, as the disease is an important contributor to the disability levels of the general population." | ( Han, D; Wang, EC, 2005) |
| "John's wort) for treatment of depression." | ( Arslan, H; Bal, N; Boga, C; Demiroglu, YZ; Kizilkilic, E; Ozdogu, H; Tuncer, I; Yeter, TT, 2005) |
| "The SSRIs are widely used to treat depression and many other psychiatric disorders." | ( Alpsan-Omay, MH; Ceylan, ME, 2005) |
| "Tianeptine treatment of depression in patients with MI in 3-7 days led to decrease of feeling of depression and lowering of anxiety." | ( Kachkovskiĭ, MA; Kriukov, NN, 2006) |
| "Tianeptine treatment of depression in patients with MI is effective, safe, well tolerated by patients and allows to decrease number of hospitalizations because of complications of cardiovascular diseases during 1 year." | ( Kachkovskiĭ, MA; Kriukov, NN, 2006) |
| "Looking ahead, improvement in treatment of depression will depend on numerous factors, including educating health care practitioners to recognize silent depression, expanding current collaborative models to cover more of the population, involving MCOs and payers in the development of effective treatment systems, and improving workplace-support programs to encourage more patients to seek appropriate care." | ( Collins, RL; Escobar, JI, 2006) |
| "After three months of treatment, depression on the Hamilton depression scale was decreased by 34% and on the Beck scale by 31% compared with baseline data ((p) < 0." | ( Levin, OS, 2007) |
| "SSRIs are established agents for the treatment of depression and are well tolerated in patients with cardiac disease." | ( Fountoulaki, K; Kremastinos, DT; Paraskevaidis, I; Parissis, J, 2007) |
| "The study showed a high degree of pre-treatment depression in smokers intending to quit." | ( Lechi, A; Lugoboni, F; Mezzelani, P; Pajusco, B; Quaglio, G, 2007) |
| "To test the hypothesis, an approach to treating depression is proposed that consists of adapted cold showers (20 degrees C, 2-3 min, preceded by a 5-min gradual adaptation to make the procedure less shocking) performed once or twice daily." | ( Shevchuk, NA, 2008) |
| "This study suggests that citalopram can treat depression and improve QoL in patients with CRF." | ( Dervisoglu, E; Kalender, B; Ozdemir, AC; Yalug, I, 2007) |
| "omega3 PUFAs are frequently employed to treat depression." | ( Bosmans, E; Kubera, M; Maes, M; Mihaylova, I, 2007) |
| "Therefore, testosterone treatment of depression must still be considered an experimental procedure." | ( Amiaz, R; Kanayama, G; Pope, HG; Seidman, S, 2007) |
| "Early diagnosis and effective treatment of depression will help the rehabilitation outcome of stroke patients." | ( Bilge, C; Koçer, A; Koçer, E; Türk Börü, U, 2008) |
| "John's wort for treating major depression, cyclothymia, or bipolar disorder is less evident." | ( Carpenter, C; Crigger, N; Kugler, R; Loya, A, 2008) |
| "A 66-year-old man received medical treatment of depression for several years." | ( Imashuku, Y; Ishikawa, Y; Kitagawa, H; Kojima, A; Kuzukawa, A; Nosaka, S, 2008) |
| "When treating a patient with treatment-resistant depression, the clinician needs to consider all factors which may contribute to an inadequate response to an antidepressant." | ( Berk, M; Dodd, S, 2008) |
| "Successful treatment of depression in three groups was fluoxetine group 50%, CBT 79." | ( Alipour, A; Esmaelzadeh, S; Faramarzi, M; Hjiahmadi, M; Kheirkhah, F; Rahnama, J, 2008) |
| "Available pharmacologic treatments for depression target monoamine levels and monoamine receptors." | ( Esposito, K; Licinio, J; Luo, HR; Reierson, GW; Wong, ML; Wu, GS, 2009) |
| "I excluded articles regarding treatment of depression in healthy young adults; bipolar disorder and attention-deficit/hyperactivity disorder; and narcolepsy, chronic fatigue syndrome, and related disorders." | ( Hardy, SE, 2009) |
| "It suggests that successfully treating depression in PD leads to important, sustained improvements in these outcomes and that patients who improve on antidepressants are less likely to relapse than are patients who initially improve on placebo." | ( Bienfait, K; Buyske, S; Dicke, A; Dobkin, RD; Gara, M; Marin, H; Mark, MH; Menza, M, 2009) |
| "Twenty-six patients with treatment-resistant depression were assessed using the suicidality item of the Montgomery-Asberg Depression Rating Scale (MADRS-SI) 2 hours before and 24 hours following a single subanesthetic dose of intravenous ketamine." | ( Charney, DS; Mathew, SJ; Nock, MK; Price, RB, 2009) |
| "Bupropion and cognitive-behavioral treatment (CBT) for depression have been used as components of treatments designed to alleviate affective disturbance during smoking cessation." | ( Abrantes, AM; Brown, RA; Kahler, CW; Leventhal, AM; Lloyd-Richardson, E; Niaura, R; Strong, DR, 2009) |
| "Most importantly, assessment and treatment of depression should be incorporated into ongoing HIV care." | ( Cunguara, A; Gloyd, SS; Jonasse, T; Matediane, E; Micek, MA; Montoya, P; Pearson, CR; Pfeiffer, J; Rao, D, 2009) |
| "To determine whether pharmacological treatment of depression in low-income minorities with diabetes improves A1C and quality of life (QOL)." | ( Bonds, C; Davidson, MB; Duran, P; Echeverry, D; Lee, M, 2009) |
| "Twenty patients with treatment-resistant depression received five 60-s 1-Hz trains over the right dorsolateral prefrontal cortex." | ( Fujita, K; Hasegawa, T; Kito, S; Koga, Y, 2010) |
| "The role of dopamine agonists in the treatment of depression is still being explored because of no sufficient number of controlled studies in this area." | ( Durst, R; Raskin, S, 2010) |
| "(Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure [SADHART-CHF]; NCT00078286)." | ( Arias, RM; Callwood, DD; Cuffe, MS; Jiang, W; Krishnan, R; Kuchibhatla, M; O'Connor, CM; Rivelli, SK; Silva, SG; Stough, WG; Zakhary, B, 2010) |
| "Concomitant FLX treatment reverted depression-like effects of CRS and led to significant increases in levels of NPY and galanin mRNA in the dentate gyrus, amygdala, and piriform cortex." | ( Christiansen, SH; Olesen, MV; Woldbye, DP; Wörtwein, G, 2011) |
| "Despite significant advances in the treatment of major depression, there is a high degree of variability in how patients respond to treatment." | ( Gong, Q; Huang, X; Jia, Z; Lui, S; Marquand, A; McGuire, P; Mechelli, A; Scarpazza, C; Wu, Q, 2011) |
| "Licensed for the treatment of depression in adults, other potential indications include seasonal affective disorder and anxiety disorders." | ( Green, B, 2011) |
| "pharmacologic treatments for depression without restrictions regarding dose, route of administration, frequency, or duration." | ( De Keyser, J; Glazenborg, A; Koch, MW; Mostert, J; Uyttenboogaart, M, 2011) |
| "Further clinical research on the treatment of depression in MS is clearly needed." | ( De Keyser, J; Glazenborg, A; Koch, MW; Mostert, J; Uyttenboogaart, M, 2011) |
| "Twenty-six patients with treatment-resistant depression received five 60-s 1-Hz trains over the right prefrontal cortex, and 12 treatment sessions were administered during 3 weeks." | ( Hasegawa, T; Kito, S; Koga, Y, 2011) |
| "The antidepressant effects of LFRS in treatment-resistant depression may be associated with decreases in rCBF in the orbitofrontal cortex and the subgenual cingulate cortex via the right prefrontal cortex." | ( Hasegawa, T; Kito, S; Koga, Y, 2011) |
| "Implications for conceptualizing and treating depression are discussed." | ( Carvalho, J; Hopko, DR; Trent, LR, 2011) |
| "Despite recent success in pharmacologic treatment of depression, the inability to predict individual treatment response remains a liability." | ( Alschuler, DM; Bruder, GE; Fekri, S; Kayser, J; Kroppmann, CJ; Manna, CG; McGrath, PJ; Schaller, JD; Stewart, JW; Tenke, CE, 2011) |
| "Untreated or inadequately treated depression is the largest risk factor for suicide." | ( Bitter, I; Czobor, P; Filipovits, D, 2011) |
| "monotherapy as initial treatment for major depression with melancholic features (MDD-MF) are unknown." | ( Bobo, WV; Chen, H; Cook, IA; Fava, M; Husain, MM; Kornstein, SG; Kurian, BT; Lesser, IM; Luther, JF; Morris, DW; Nierenberg, AA; Rush, AJ; Shelton, RC; Stewart, JW; Trivedi, MH; Warden, D; Wisniewski, SR, 2011) |
| "A well-validated animal model of treatment resistant depression (congenital learned helpless rats = cLH) was investigated by hippocampal in vivo ¹H MRS with and without a 1-week course of electroconvulsive shocks (ECS), an animal model of ECT, and compared to wild type (WT) animals, while saline and clomipramine injections served as additional controls." | ( Biedermann, S; Ende, G; Gass, P; Hoyer, C; Sartorius, A; Vollmayr, B; Weber-Fahr, W; Zheng, L, 2012) |
| "Low-dose ketamine has been used to treat both pain and depression, but it is not clear whether ketamine can relieve depression associated with chronic pain and whether this antidepressant effect depends on its antinociceptive properties." | ( Blanck, TJ; Eberle, SE; Goffer, Y; Shamir, DB; Tukey, DS; Wang, J; Xu, D; Ziff, EB; Zou, AH, 2011) |
| "Low-dose ketamine can treat depression-like behaviors induced by chronic neuropathic pain." | ( Blanck, TJ; Eberle, SE; Goffer, Y; Shamir, DB; Tukey, DS; Wang, J; Xu, D; Ziff, EB; Zou, AH, 2011) |
| "Current pharmacological treatments for depression have a significant treatment-onset-response delay, an insufficient efficacy for many patients and fail to reverse cognitive dysfunction." | ( Ehrenreich, H; Harmer, CJ; Kessing, LV; Miskowiak, KW; Vinberg, M, 2012) |
| "Thus, to improve the treatment of depression; behavioral consequences of diverse housing conditions should be taken into consideration." | ( Erol, K; Ulupinar, E; Yildirim, E, 2012) |
| "Among carers of patients with treatment-resistant depression (TRD), we set out to determine the psychological and physiological (HPA axis) consequences of caring, and the association of these consequences with long-term outcome in patients." | ( Cleare, AJ; Fekadu, A; Markopoulou, K; Papadopoulos, AS; Poon, L; Rane, LJ; Wooderson, SC, 2012) |
| "It is commonly used for the treatment of depression-related syndromes in China." | ( Gao, X; Jia, G; Ma, Z; Qin, X; Ren, Y; Zhang, L; Zhou, Y, 2012) |
| "In contrast, treatment for depression remains to be elucidated in HFpEF." | ( Hatano, M; Hirata, Y; Imai, Y; Kato, N; Kazuma, K; Kinugawa, K; Nagai, R; Shiga, T; Takeda, N; Watanabe, M; Yao, A, 2012) |
| "While treatment of depression in major depressive disorder may partially ameliorate cognitive deficits, the cognitive effects of antidepressant medications in patients with schizophrenia or schizoaffective disorder and SSD are unknown." | ( Dawes, SE; Golshan, S; Kasckow, J; Meeks, T; Mohamed, S; Palmer, BW; Zisook, S, 2012) |
| "Rose oil may be a useful treatment for depression because it contains flavonoids which include free radical antioxidant compounds such as rutin and quercetin." | ( Karakuş, K; Kozlu, S; Nazıroğlu, M; Uğuz, AC; Yorgancıgil, E, 2013) |
| "Details of treatment for depression were obtained from primary care records." | ( Burton, C; McGorm, K; Sawhney, A; Sharpe, M; Weller, D, 2012) |
| "To date, 163 patients, primarily with treatment-resistant depression, have participated in case studies, open-label investigations, or controlled trials." | ( Aan Het Rot, M; Charney, DS; Mathew, SJ; Zarate, CA, 2012) |
| "(Exercise to Treat Depression in Individuals With Coronary Heart Disease; NCT00302068)." | ( Babyak, MA; Blumenthal, JA; Doraiswamy, PM; Hinderliter, AL; Hoffman, BM; Jiang, W; Johnson, J; Mabe, S; O'Hayer, CV; Schocken, DD; Sherwood, A; Smith, PJ; Watkins, LL, 2012) |
| "Reboxetine has been approved for the treatment of Major Depression in many European countries, but the application for approval was rejected in the United States." | ( Corbo, M; Fiori, F; Martinotti, G; Sepede, G, 2012) |
| "Behavioral activation (BA) is a treatment for depression that involves learning to reengage in life's activities." | ( Mayer, KH; Mimiaga, MJ; O'Cleirigh, C; Pantalone, DW; Reisner, SL; Safren, SA, 2012) |
| "As expected, chronic estradiol treatment decreased depression-like behavior, as measured by the duration of immobility, in saline-treated mice from two different strains, as well as in mice treated with LPS in adulthood." | ( Blaustein, JD; Ismail, N; Kumlin, AM, 2013) |
| "We investigated whether treating depression in older participants impacted on arterial stiffness, a known cardiovascular disease risk factor and a clinical marker of arterial aging." | ( Assisi, AP; Fedullo, F; Gianni, W; Modestino, A; Scuteri, A, 2013) |
| "Magnesium seems to be effective in the treatment of depression but data are scarce and incongruous." | ( Derom, ML; Martínez-González, MA; Martínez-Ortega, JM; Sayón-Orea, C, 2013) |
| "Alternative treatments for depression, including nutritional supplements, are an important treatment option for depressive symptoms while limiting potential side effects and treatment costs." | ( Humphries, D; Rechenberg, K, 2013) |
| "Use of homeopathy to treat depression is widespread but there is a lack of clinical trials about its efficacy in depression in peri- and postmenopausal women." | ( Aguilar-Faisal, L; Asbun-Bojalil, J; Macías-Cortés, Edel C, 2013) |
| "Recognition and treatment of depression in T2DM are important because of its association with hyperglycemia, diabetic complications and poor quality of life (QoL)." | ( Chacártegui, B; Francés, C; Masmiquel, L; Nicolau, J; Rivera, R, 2013) |
| "Preferred drugs for treating depression in epilepsy are serotonin reuptake inhibitors." | ( Castaño-Monsalve, B, 2013) |
| "Monoamine-based treatments for depression have evolved greatly over the past several years, but shortcomings such as suboptimal efficacy, treatment lag, and residual cognitive dysfunction are still significant." | ( Pehrson, AL; Sanchez, C, 2014) |
| "Atomoxetine (ATX), a drug for treatment of depression and ADHD, has a high affinity for the norepinephrine transporter (NET); however, our previous study showed it had a blocking effect similar to fluoxetine on binding of [(11)C]DASB, a selective serotonin transporter (SERT) ligand." | ( Carson, RE; Ding, YS; Gallezot, JD; Huang, Y; Laruelle, M; Lin, SF; McCarthy, TJ; Nabulsi, N; Naganawa, M; Ropchan, J; Weinzimmer, D, 2014) |
| "Sertraline is widely prescribed to treat depression and anxiety disorders." | ( Boyapati, R; Dev, A; Simpson, I; Suen, CF, 2013) |
| "Electro-acupuncture is effective for treating depression and affects personality traits." | ( Hong, L; Lin, YN; Lu, XY; Ng, SM; Wang, F; Wang, WD; Zhao, Y, 2013) |
| "Outcomes were treated depression and fatal and non-fatal self harm within three months of the first smoking cessation prescription, determined from linkage with mortality data from the Office for National Statistics (for suicide) and Hospital Episode Statistics data (for hospital admissions relating to non-fatal self harm)." | ( Davies, NM; Gunnell, D; Martin, RM; Metcalfe, C; Thomas, KH; Windmeijer, F, 2013) |
| "Current treatments for depression are characterized by a low success rate and associated with a wide variety of side effects." | ( Doron, R; Einat, N; Kately, N; Lotan, D; Marom, I; Meron, G; Rehavi, M; Winer, A; Yaffe, R, 2014) |
| "Higher pre-treatment depression scores and lower pre-treatment anxiety scores are the two most important predictors for improvement during antidepressant treatment in depressed PD patients, which is in line with those found in treatment studies of depressed non-PD patients." | ( Auinger, P; Christine, CW; Factor, SA; Juncos, J; Leentjens, AF; Lyness, JM; Marsh, L; McDonald, W; Moonen, AJ; Panisset, M; Pfeiffer, R; Richard, IH; Rottenberg, D; Serrano Ramos, C; Shulman, L; Singer, C; Slevin, J; Wijers, A, 2014) |
| "The efficiency of EA treatment for depression and the mechanism of it were discussed, to shed light on new ideas and new fronts for the further research on depression in clinical or pre-clinical fields." | ( Li, ZG; Mo, YP; Song, HT; Tang, YS; Xu, AP; Yao, HJ, 2014) |
| "A case of successful treatment for depression with varenicline is described." | ( Kausch, O, 2014) |
| "Bupropion may be an alternative treatment for depression that does not include the sexual side effects associated with most of the prescribed antidepressants available; however, additional research is required." | ( Arias-Carrión, O; Machado, S; Nardi, AE; Pereira, VM; Silva, AC, 2014) |
| "The aim of treatment of depression is remission of symptoms and functioning." | ( Berggren, L; Gilaberte, I; Lenox-Smith, A; Pérez, V; Quail, D; Romera, I, 2014) |
| "133 patients with treatment-resistant depression (major depressive disorder or bipolar I/II disorder) received a single subanesthetic infusion of ketamine (0." | ( Ameli, R; Ballard, ED; Brutsché, NE; Furey, ML; Ionescu, DF; Luckenbaugh, DA; Niciu, MJ; Richards, EM; Vande Voort, JL; Zarate, CA, 2014) |
| "Furthermore, in addition to treating depression, antidepressants such as amitriptyline are a first-line treatment for chronic pain conditions, indicating possible common neural substrates underlying both depression and pain." | ( Burke, NN; Finn, DP; Roche, M, 2015) |
| "Before and after treatment, Hamilton depression rating scale (HAMD) was applied to judge the curative effect, and the changes of cerebral neurotransmitters levels in the brain of patients were detected by encephalofluctuograph technique." | ( Li, M; Li, SD; Liu, Y; Wang, HM; Yang, MH, 2014) |
| "Does the treatment of depression in elderly subjects using pharmacological compounds or phytomedical extracts target a mechanism that also accounts for peptide storage in Alzheimer's disease and perhaps other proteopathies of the brain? In this review we summarize recent data that point to a common mechanism and present the first promising causal treatment results of demented elderly subjects with distinct SJW extracts." | ( Årsland, D; Bogdanovic, N; Fröhlich, C; Krohn, M; Paarmann, K; Pahnke, J; Winblad, B, 2014) |
| "Successful treatment of depression has beneficial effects on sleep outcomes in these patients." | ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yoon, JS, 2015) |
| "We speculate that treating depression or lowering MED may mitigate a bidirectional association and ultimately improve pain management." | ( Burge, S; Lustman, PJ; Salas, J; Scherrer, JF; Schneider, FD, 2015) |
| "In a previous pilot study, L-T4 treatment reduced depression scores and activity within the anterior limbic network." | ( Adli, M; Bauer, M; Berman, S; Hellemann, GS; London, ED; Pilhatsch, M; Plotkin, M; Schlagenhauf, F; Stamm, T; Whybrow, PC, 2016) |
| "Use of homeopathy to treat depression is widespread but there is a lack of clinical trials about its efficacy in depression in peri- and postmenopausal women." | ( Aguilar-Faisal, L; Asbun-Bojalil, J; Llanes-González, L; Macías-Cortés, Edel C, 2015) |
| "Celecoxib is a safe and effective treatment for depression due to brucellosis when compared with placebo." | ( Akhondzadeh, S; Ashrafizadeh, SG; Entezari, P; Jafari, S; Rasoulinejad, M; Seddighi, S; Zeinoddini, A, 2015) |
| "Exercise is considered as a treatment for depression, but mechanisms underlying its beneficial effects still remain unknown." | ( Ji, L; Li, H; Liu, W; Wang, H; Wang, Y, 2015) |
| "IFN-α treatment induced depression-like behaviour by increasing immobility in the forced swim test (FST), and decreased tryptophan levels in the brain." | ( Budac, DP; Elfving, B; Eskelund, A; Fischer, CW; Liebenberg, N; Tillmann, S; Wegener, G, 2015) |
| "Several non-pharmacological treatments of depression upregulate adenosine concentration and/or adenosine A1 receptors (A1R) in the brain." | ( Biber, K; Clement, HW; de Bartolomeis, A; Iasevoli, F; Idzko, M; Jacobson, KA; Normann, C; Schwarz, MK; Serchov, T; Tosh, DK; van Calker, D, 2015) |
| "During IFN-α treatment Hamilton Depression Rating Scale scores rise significantly." | ( Amouzadeh-Ghadikolai, O; Baranyi, A; Breitenecker, RJ; Meinitzer, A; Rothenhäusler, HB; Stauber, R, 2015) |
| "Compared to non-treated depression-like rats, the increased levels of 5-hydroxytryptamine (5-HT) and 5-hydroxyindoleacetic acid (5-HTAA) in serum and hypothalamus, and the reduced expressions of 5-HT1A receptor and 5-HT2A receptor in hypothalamus were observed after AF and fluoxetine oral administration indicating that AF-mediated antidepressant-like effect may be related to the normalization of serotonergic system." | ( Hou, X; Hu, X; Liu, C; Liu, W; Lu, C; Song, J; Teng, L; Wang, D; Wang, J, 2015) |
| "pharmacologic treatment of depression in HD patients for patient-centered outcomes." | ( Cohen, S; Comstock, B; Cukor, D; Daniel, DM; Dember, LM; Diaz-Linhart, Y; Dubovsky, A; Greene, T; Grote, N; Heagerty, P; Hedayati, SS; Katon, W; Kimmel, PL; Kutner, N; Linke, L; Mehrotra, R; Quinn, D; Rue, T; Trivedi, MH; Unruh, M; Weisbord, S; Young, BA, 2016) |
| "However, CLN treatment increased depression." | ( Arora, S; Vohora, D, 2016) |
| "Bupropion is used for treatment of depression during pregnancy." | ( Ahmed, MS; Clark, SM; Fokina, VM; Hankins, GD; Nanovskaya, TN; Oncken, C; West, H, 2016) |
| "Guidelines suggest treatment of depression in dialysis patients with pharmacological therapy, preferably a selective serotonin reuptake inhibitor." | ( Craig, JC; Natale, P; Palmer, SC; Rabindranath, KS; Ruospo, M; Saglimbene, VM; Strippoli, GF, 2016) |
| "Successful treatment of depression and anxiety with escitalopram had significant beneficial effects on suicidal ideation in these patients." | ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, H; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Yoon, JS, 2016) |
| "These findings suggest that DHEA treatment induced depression-like behavior in PCOS mice, possibly through down-regulation of brain monoamines and/or their metabolites, which implies the contribution of hyperandrogenism to the psychological symptoms of women with PCOS." | ( Hao, S; Kang, J; Shen, Q; Song, X; Wang, H; Yu, Q, 2016) |
| "Fluoxetine is widely used to treat depression, including depression in pregnant and postpartum women." | ( Lin, S; Liu, L; Pei, S; Shang, J; Wang, H; Zhong, Z, 2016) |
| "Twelve subjects with mild or moderate treatment-resistant depression were randomized into a double-blind crossover trial to receive an infusion of 4 g of magnesium sulfate in 5% dextrose or placebo infusion of 5% dextrose with a 5-day washout in between the 8-day intervention period." | ( Abbas, MH; Arosemena, L; Atlas, SE; Caccamo, S; Campbell, CS; Corredor, R; Farooqi, A; Gao, J; Goldberg, S; Konefal, J; Lages, LC; Lantigua, L; Lewis, JE; Lopez, J; Mehdi, SM; Musselman, D; Padilla, V; Qadir, S; Rasul, A; Ray, AM; Simões, HG; Tiozzo, E; Woolger, JM, 2017) |
| "To develop drug therapies for the treatment of depression, it is necessary to use animal models of depression to screen drug candidates that exhibit anti-depressive effects." | ( Goto, T; Kohari, D; Okayama, T; Otabi, H; Toyoda, A, 2017) |
| "As most current treatments for depression require an extended period of administration, our current results suggest that melatonin may prove to be a particularly effect agent to promote a rapid onset and prolonged behavioral benefits in the treatment of depression." | ( Li, Q; Lian, B; Sun, H; Sun, L; Sun, X; Wang, G; Wang, M; Wang, Y, 2017) |
| "The pharmacological treatment of major depression is mainly based on drugs elevating serotonergic (5-HT) activity." | ( Borroto-Escuela, DO; Díaz-Cabiale, Z; Flores-Burgess, A; Fuxe, K; Gago, B; Mengod, G; Millón, C; Narváez, JA; Narváez, M; Santín, L, 2017) |
| "Thirty users of SSRIs for treatment of depression or anxiety were enrolled in the study." | ( Aksoy, S; Atıcı, M; Erdogan, MS; Ertaş, ET; Isa Kara, M; Kelebek, S; Ozen, E, 2017) |
| "Current treatments for depression are characterized by a low success rate and associated with a wide variety of side effects." | ( Huang, M; Lu, X; Wang, Y; Wei, R; Xu, J, 2017) |
| "Fluoxetine (Flx) is a first-line treatment for depression; however, its downstream mechanisms of action beyond serotonergic signaling remain ill-defined." | ( Filipović, D; Gass, P; Perić, I; Stanisavljević, A, 2017) |
| "This often makes the decision to treat prenatal depression with pharmacotherapy (i." | ( Oberlander, TF; Rotem-Kohavi, N, 2017) |
| "Childhood maltreatment and depression have both been associated with dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis-a key regulator of the body's stress response." | ( Aiello, AE; Bustamante, AC; Galea, S; Guffanti, G; Uddin, M; Wildman, DE, 2018) |
| "It is licensed to treat depression, but it is also commonly used off-label to treat insomnia." | ( Settimo, L; Taylor, D, 2018) |
| "Efforts to diagnose and treat depression appropriately, especially if depressive symptoms change in patients undergoing ADT to treat prostate cancer who are using an LHRH agonist (leuprolide), have low testosteronelevel, or are older at the age when initiating ADT." | ( Chung, KJ; Jung, H; Kim, CH; Kim, KH; Kim, KT; Kim, TB; Oh, JK; Yoon, SJ, 2018) |
| "When considering treating perinatal depression with a drug indicated for the treatment of depression, the major concerns are whether the drug increases the risks of teratogenicity, pregnancy complications, poor neonatal adaptation, or neurodevelopmental disorders." | ( Albertini, ES; Ernst, C; Fersh, ME; Habib, S; Khan, SJ; Lusskin, SI, 2018) |
| "On 14th day of the treatment, depression-like behaviour was induced by LPS (0." | ( Barua, CC; Haloi, P; Pathak, DC; Ren, X; Rizavi, H; Saikia, B; Sulakhiya, K; Tamuli, S, 2018) |
| "There is a strong correlation between treatment resistant depression and increase in inflammatory cytokines in plasma and cerebrospinal fluid." | ( Abagyan, R; Cohen, IV; Lee, KC; Makunts, T, 2018) |
| "To screen the target for the treatment of depression of Acori Tatarinowii Rhizoma and Curcumae Radix using the pharmacological method of network pharmacology, in order to define the mechanism of antidepressant effect." | ( Fan, WT; Wang, Q, 2018) |
| "In patients without pretreatment depression, TRT leads to a reduction of scores for depressive symptoms; however, clinical value of this is difficult to measure." | ( Kimura, S; Shariat, SF; Vartolomei, L; Vartolomei, MD, 2020) |
| "Therefore, beyond optimizing the treatment of depression in patients, the issue of stigma among caregivers also needs to be addressed as a potential target of intervention." | ( Chai, YC; Chan, LF; Mahadevan, R; Md Dai, F; Ng, CG, 2018) |
| "Fluoxetine successfully treated depression-like behavior but had no effects on the white matter or its component myelinated fibers in the CUS rat model of depression." | ( Chao, FL; Chen, LM; Du, L; Gao, Y; Huang, CX; Liang, X; Luo, YM; Ma, J; Qi, YQ; Tang, J; Tang, Y; Wang, SR; Xiao, Q; Yao, Y; Zhang, L; Zhang, Y, 2019) |
| "Although in treatment-resistant depression (TRD) subgenual anterior cingulate cortex (sgACC) functional connectivity (FC) is frequently used to examine deregulated brain networks, neurobiological data from other sources may be required to interpret these FC findings." | ( Baeken, C; De Raedt, R; Van Schuerbeek, P; Wu, GR, 2020) |
| "These results indicate that SERT might treat depression by inhibiting the activation of microglia via the NF-κB signaling pathway." | ( Cheng, JH; Jiang, T; Jin, L; Jin, XJ; Lu, Y; Ma, J; Piao, HN; Piao, LX; Xu, X; Zhao, XD, 2019) |
| "However, the role of statins in the treatment of depression has not been well examined." | ( An, YQ; Dai, Y; Hu, LF; Lin, GY; Tang, CR; Xu, HQ; Xu, RA; Yu, XB; Zhang, CH; Zhang, HN; Zhou, ZY, 2019) |
| "After 12 weeks of treatment, depression scores were modestly better with sertraline treatment than with CBT." | ( Cohen, SD; Cukor, D; Dember, LM; Diaz-Linhart, Y; Dubovsky, A; Greene, T; Grote, N; Heagerty, P; Hedayati, SS; Kimmel, PL; Kutner, N; Mehrotra, R; Quinn, DK; Rue, T; Trivedi, MH; Unruh, M; Ver Halen, N; Weisbord, SD; Young, BA, 2019) |
| "We compared two treatments for depression and/ or anxiety in chronic moderate to severe traumatic brain injury (TBI) (Clinicaltrials." | ( Chervoneva, I; Collier, G; Fann, JR; Hart, T; Vaccaro, M, 2020) |
| "However, therapeutic treatments for depression or research on depression is scarce." | ( Kim, HJ; Lee, DK; Son, H; Yang, JH, 2019) |
| "For medication-treated depression, the HRs (CIs) were 1." | ( Adam, E; Hatch, EE; Hoover, RN; Huo, D; Hyer, M; Palmer, JR; Ricker, W; Strohsnitter, WC; Titus, L; Troisi, R, 2019) |
| "Recognition and treatment of depression in taxi drivers are important." | ( Burgel, BJ; Elshatarat, RA, 2019) |
| "Medication is commonly used to treat youth depression, but whether medication should be added to cognitive behavioural therapy (CBT) as first-line treatment is unclear." | ( Amminger, GP; Berk, M; Catania, L; Chanen, AM; Cotton, SM; Davey, CG; Dean, OM; Harrison, BJ; Hetrick, SE; Kazantzis, N; Kerr, M; Koutsogiannis, J; McGorry, PD; Mullen, E; Parker, AG; Phelan, M; Quinn, AL; Ratheesh, A; Rice, S; Weller, A, 2019) |
| "Escitalopram, a drug of choice in the treatment of depression, was recently shown to possess an anti-inflammatory activity." | ( Abdelsalam, RM; Abdo, SA; Khattab, MM; Wadie, W, 2019) |
| "Additionally, the use in the treatment of depression substance with neuroprotective, antioxidant and antidepressant-like effects in the CNS and existing endogenously might be also beneficial in controlling the adverse CNS inflammatory processes accompanying depression." | ( Antkiewicz-Michaluk, L; Babińska, I; Możdżeń, E; Wójcikowski, J, 2019) |
| "However, the effects of repeated NAC treatment on depression-induced anxiety, cognitive deficits, and associated neurochemical and structural alterations are relatively unknown." | ( Chakraborty, S; Raju, TR; Shankaranarayana Rao, BS; Srikumar, BN; Tripathi, SJ, 2020) |
| "Concerns about ketamine for treating depression include abuse potential and the occurrence of psychotomimetic effects." | ( Acevedo-Diaz, EE; Cavanaugh, GW; Greenstein, D; Kadriu, B; Kraus, C; Park, LT; Zarate, CA, 2020) |
| "The pathophysiology and treatment of depression have been the focus of intense research and while there is much that remains unknown, modern neurobiological approaches are making progress." | ( Deyama, S; Duman, RS; Fogaça, MV, 2021) |
| "Slow response to the standard treatment for depression increases suffering and risk of suicide." | ( Chandra, J; Klein, ME; Malinow, R; Sheriff, S, 2020) |
| "To quantify the risk of incident treated anxiety, depression and mixed anxiety + depression in users of apremilast compared with users of other treatments for psoriasis and PsA." | ( Hagberg, KW; Jick, S; Persson, R; Vasilakis-Scaramozza, C, 2020) |
| "We conclude that screening for and treating depression among PLHIV in SSA with fluoxetine would be effective in improving HIV treatment outcomes and would be highly cost-effective." | ( Arjmand, IK; Bendavid, E; Brandeau, ML; Zhong, H, 2021) |
| "When treating depression, we should consider the risks and benefits of combination therapy in individual patients and take measures to minimize the side effects of medicines." | ( Červeňová, J, 2019) |
| "for intranasal ESK in 2013 for treatment-resistant depression (TRD) and in 2016 for the treatment of MDD with an imminent risk of suicide." | ( De Berardis, D; Di Giannantonio, M; Fornaro, M; Fraticelli, S; Kim, YK; Martinotti, G; Orsolini, L; Perna, G; Pompili, M; Serafini, G; Tomasetti, C; Valchera, A; Vellante, F; Volpe, U, 2020) |
| "Traditional monoaminergic treatments of depression frequently exhibit suboptimal tolerability and effectiveness." | ( Hannan, AJ; Li, S; Renoir, T; Wilson, C, 2020) |
| "Corticosterone treatment induced depression-like behaviors, it increased immobility time in the TST, OFT, and FST, decreased the number of movements in OFT, and decreased sucrose consumption." | ( Al-Rasheed, N; Attia, HA; Badr, AM, 2020) |
| "The adjustment of SUA as a method for treating depression needs to be carefully assessed." | ( Deng, W; Huang, X; Li, J; Li, T; Meng, X, 2020) |
| "Prevention and treatment of depression is especially important for young females." | ( Crosby, AE; Halpin, J; Holland, KM; Ivey-Stephenson, A; Sumner, SA; Wang, J, 2020) |
| "Moreover, the treatment of depression and anxiety can be associated with a reduced mortality." | ( Aguglia, E; Migliore, M; Signorelli, MS; Surace, T, 2020) |
| "Response rates to first-line treatments for depression and anxiety remain unsatisfactory." | ( Craske, MG; Meuret, AE; Ritz, T; Roque, AD; Rosenfield, D; Treanor, M, 2020) |
| "There is a large "treatment gap" for depression worldwide." | ( Patel, V; Rathod, SD; Roberts, T; Shidhaye, R, 2020) |
| "Evaluate pimavanserin treatment for depression in patients with PD." | ( Abler, V; Aldred, JL; Alva, G; Cantillon, M; Coate, B; DeKarske, D; Jacobi, L; Norton, JC; Nunez, R, 2020) |
| "Bright light therapy (BLT) is known to treat depression and sleep disorders in clinical practice, but its efficacy on poststroke depression (PSD) has not been studied." | ( Chen, S; Feng, L; He, J; Luan, X; Wang, Q; Xiao, M, 2021) |
| "KOK might be useful for the treatment of depression caused by environmental and lifestyle-related stress." | ( Chin, YW; Jeon, S; Kim, YM; Koo, BS; Liu, QF; Pak, SC; Park, SW; Song, SJ, 2021) |
| "Despite the available therapies for treatment-resistant depression (TRD), there are a limited number that are evidence-based and effective in this hard-to-treat population." | ( Cubała, WJ; Fagiolini, A; Kasper, S; Ramos-Quiroga, JA; Souery, D; Young, AH, 2021) |
| "Participants believed MC can treat depression and/or anxiety." | ( Mansfield, K; Webb, M, 2021) |
| "One-third of patients with treatment-resistant depression demonstrate resistance to ketamine, which is a novel antidepressant effective for this disorder." | ( Abe, T; Hiraki, T; Horikawa, N; Ishibashi, M; Nakamura, T; Tomita, M; Uchimura, N; Uematsu, K, 2021) |
| "Fifteen patients with treatment-resistant depression received multiple intravenous subanesthetic (0." | ( Abe, T; Hiraki, T; Horikawa, N; Ishibashi, M; Nakamura, T; Tomita, M; Uchimura, N; Uematsu, K, 2021) |
| "Effective treatment of depression is a key target for suicide prevention strategies." | ( Berk, M; Chanen, A; Cotton, S; Davey, CG; Dean, O; Hetrick, S; Madsen, T; McGorry, PD; Witt, K, 2021) |
| "Searching for more effective treatments for depression is a long-standing primary objective in neuroscience." | ( Amin, N; Chen, F; Chen, S; Fang, M; Jin, W; Liu, J, 2021) |
| "Seven patients with treatment-resistant depression enrolled in an open-label, feasibility trial of a single IV 40-min ketamine infusion during a functional MR spectroscopy (fMRS) scan utilizing a novel frequency adjusting MEGA-PRESS sequence." | ( Coombes, BJ; Frye, MA; Geske, JR; Lanza, IR; Morgan, RJ; Port, JD; Singh, B; Voort, JLV, 2021) |
| "Adults with treatment-resistant depression (TRD) receiving intravenous (IV) ketamine had depressive symptoms measured with the 16-Item Quick Inventory Depressive Symptoms Self-Report (QIDS-SR-16) and MARRRS at baseline and as a repeated measure across an acute course of four infusions." | ( Cha, DS; Gill, H; Ho, R; Kratiuk, K; Lee, Y; Lipsitz, O; Lui, LMW; Mansur, RB; McIntyre, RS; Rodrigues, NB; Rosenblat, JD; Subramaniapillai, M, 2021) |
| "Lamotrigine is used to treat bipolar depression despite inconsistent evidence." | ( Balbuena, L; Li, H; Lodhi, RJ; Peters, EM; Zhang, Y, 2021) |
| "Among 108 patients with treatment resistant depression (50 females), we evaluated cross-sectional relationships between IL-8 and depression severity, as measured by the Hamilton Depression Rating Scale [HAM-D] Score, and examined sex-specific relationships, as well as relationships with depressive symptom profiles." | ( Breen, EC; Brooks, JO; Congdon, E; Espinoza, R; Hellemann, G; Irwin, MR; Kruse, JL; Narr, KL; Olmstead, R; Tye, SJ; Wade, B, 2021) |
| "One third among them will suffer from treatment resistant depression (TRD) which does not respond to two accepted treatment protocols." | ( Marom, A; Rosca, P, 2021) |
| "Fluoxetine is often prescribed to treat depression during pregnancy." | ( Ampuero, E; de Vries, EF; Díaz-Galarce, R; Donoso-Ramos, JP; Doorduin, J; Linsambarth, S; Moraga-Amaro, R; Pacheco, R; Peña, F; Stehberg, J; Ugalde, V; Wyneken, U, 2021) |
| "Effective strategy for the treatment of depression is limited." | ( Cao, C; Chen, LH; Fan, Y; Hu, H; Jiang, C; Li, Y; Liu, J; Liu, T; Luo, W; Tang, Z; Wu, W; Xu, Y; Zhang, Q, 2021) |
| "Receiving treatment for depression is increasingly common among young adults." | ( Lähteenvuo, M; Lampela, P; Taipale, H; Tanskanen, A; Tiihonen, J, 2021) |
| "Among the patients who treat depression, about 50% do not show significant improvement due to the limited efficacy of the treatment." | ( Costa, BLDSAD; Duarte-Silva, EP; Melo, MG; Mendonça, IP; Oliveira, WH; Paiva, IHR; Peixoto, CA; Silva, RSD, 2022) |
| "Various approaches already exist for treating depression but, none of them are completely successful in treating depression." | ( Patel, MR; Patel, RB; Rao, HR; Thakkar, DV, 2022) |
| "A breakthrough in the treatment of depression was the discovery that the anesthetic (R,S)-ketamine (ketamine), when administered at sub-anesthetic doses, elicits rapid (sometimes within hours) antidepressant effects in humans that are otherwise resistant to monoaminergic-acting therapies." | ( Gould, TD; Hess, EM; Michaelides, M; Riggs, LM, 2022) |
| "After treatment, depression score (SMD = -2." | ( Li, G; Liu, W; Wang, C; Wang, X; Yang, L, 2021) |
| "Ketamine is efficacious in treating treatment-resistant depression in medical settings and the drug was approved for such use by the US Federal Drug Administration in 2019." | ( Han, BH; Kumar, S; Palamar, JJ; Yang, KH, 2022) |
| "In addition, the benefits of metformin treatment of depression have been documented in a range of rodent studies and human trials, but few studies have probed into the effect of metformin on and the related mechanism in depressed elderly mice, especially in those APOE4 carriers." | ( Chen, X; Dai, X; Lin, Y; Zhang, J, 2022) |
| "Additionally, its important role in treating depression, depressed mood disorders and anti-inflammation has been proven in previous studies." | ( Chang, B; Hu, J; Jia, A; Liu, Y; Qiu, Z; Song, Z; Tang, Z; Zhang, Y, 2022) |
| "Esketamine was licensed for use in treatment resistant depression by the European Medicines Agency in December 2019." | ( Curran, HV; Freeman, TP; Grabski, M; van Laar, M; Waldron, J, 2022) |
| "Examine SSRIs' efficacy in treating depression, anxiety, PTSD, and substance use in individuals with addiction." | ( Fluyau, D; Jain, A; Kailasam, VK; Mitra, P; Pierre, CG, 2022) |
| "The approval of ketamine for treatment-resistant depression has created a model for a novel class of rapid-acting glutamatergic antidepressants." | ( Kadriu, B; Kojic, M; Kraus, C; Saelens, J; Zarate, CA, 2022) |
| "Self-reported diagnosed and treated depression within the last 12 months and the moderation effect of substance use on the association between sexual dysfunction and depression." | ( Becher, H; Belau, MH; Briken, P; von Rüden, U; Wiessner, C, 2022) |
| "Meanwhile, existing treatment of depression is dominated by antidepressants, which produce troublesome side effects and usually require months to achieve effect." | ( Che, F; Ding, Q; Li, P; Liu, Z; Tang, B; Wang, R; Wang, X; Wu, W; Zhang, W, 2022) |
| "Esketamine is a novel treatment for treatment resistant depression (TRD) and was approved by the FDA in early 2019." | ( Cook, J; Halaris, A, 2022) |
| "Venlafaxine + melatonin treatment improves depression-like behaviour, pentobarbital sodium experimental sleep latency, and sleep duration in CUMS +SD rats." | ( Han, YS; Jiang, HX; Li, CY; Li, ZR; Liu, DG; Wang, YH; Xie, S; Zou, MS, 2022) |
| "50 (33%) were currently being treated for depression." | ( Clifton, J; Littenberg, B; Mason, H; MIller, A; Natkin, L; Tarleton, E, 2022) |
| "Due to the resistance to treat depression, better understanding of neurophysiology was considered; one of the implications is the glutamatergic system." | ( Shamabadi, A, 2022) |
| "Thirty-eight patients with treatment-resistant depression were administered cognitive assessments before and after undergoing 7 i." | ( Batten, LA; Blier, P; Burhunduli, P; Norris, S; Ortiz, A; Owoeye, O; Phillips, JL; Talbot, J; Van Geel, A; Vasudev, D, 2022) |
| "We investigated the effects of T3 treatment on the depression-like behavior in male transgenic 3xTg-AD mice." | ( Britto, LRG; da Conceição, RR; da Silva, REC; de Souza, JS; de Souza, TJL; do Nascimento, BPP; Giannocco, G; Laureano-Melo, R; Maciel, RMB; Maglione, AV; Penatti, CAA; Ribeiro, MO; Sato, MA, 2022) |
| "Also, in patients with treatment resistant depression or depression with atypical features combined with intermittent hypercortisolism psychiatrists have to consider a cyclic Cushing syndrome." | ( Lapauw, B; Lemmens, G; Snauwaert, P; Van de Velde, N; Zaman, E, 2022) |
| "In order to prevent and treat adolescent depression, this study examines the mechanisms of educational reinforcement and punishment as well as psychological interventions." | ( Chen, H; Wu, W, 2022) |
| "Major depressive disorder (MDD) and treatment-resistant depression (TRD) represent a global source of societal and health burden." | ( Gu, J; Sukhram, SD; Yilmaz, G, 2022) |
| "Patients with treatment-resistant depression (TRD) and healthy volunteer participants aged 34 to 68 years were included." | ( Bottemanne, H; Claret, A; Fossati, P; Morlaas, O; Schmidt, L; Sharot, T, 2022) |
| "Predicting relapse during maintenance treatment for depression is challenging." | ( Kubo, K; Mimura, M; Sakurai, H; Tani, H; Uchida, H; Watanabe, K, 2023) |
| "With the ZZCD treatment, the depression was improved, but the exposures of anti-depressive compounds from ZZCD gradually decreased." | ( Chen, XF; Cui, LX; Fang, YC; Gao, CC; Gao, FY; Huang, TH; Liu, JL; Wen, J; Zhai, YJ; Zhou, TT, 2023) |
| "With the ZZCD treatment, the depression was improved, but the exposures of anti-depressive compounds from ZZCD gradually decreased." | ( Chen, XF; Cui, LX; Fang, YC; Gao, CC; Gao, FY; Huang, TH; Liu, JL; Wen, J; Zhai, YJ; Zhou, TT, 2023) |
| "With the ZZCD treatment, the depression was improved, but the exposures of anti-depressive compounds from ZZCD gradually decreased." | ( Chen, XF; Cui, LX; Fang, YC; Gao, CC; Gao, FY; Huang, TH; Liu, JL; Wen, J; Zhai, YJ; Zhou, TT, 2023) |
| "Nineteen patients with treatment-resistant depression received a low oral dose (10 mg) of psilocybin, and a high dose (25 mg) 1 week later." | ( Carhart-Harris, R; Kaelen, M; Nutt, D; Roseman, L; Shukuroglou, M; Wall, M, 2023) |
| "Nineteen patients with treatment-resistant depression received a low oral dose (10 mg) of psilocybin, and a high dose (25 mg) 1 week later." | ( Carhart-Harris, R; Kaelen, M; Nutt, D; Roseman, L; Shukuroglou, M; Wall, M, 2023) |
| "Nineteen patients with treatment-resistant depression received a low oral dose (10 mg) of psilocybin, and a high dose (25 mg) 1 week later." | ( Carhart-Harris, R; Kaelen, M; Nutt, D; Roseman, L; Shukuroglou, M; Wall, M, 2023) |
| "Most research describing ketamine as a treatment for depression has relied on intravenous dosing." | ( Cheveldae, I; Halpape, K; Peters, EM; Wanson, A, 2023) |
| "Most research describing ketamine as a treatment for depression has relied on intravenous dosing." | ( Cheveldae, I; Halpape, K; Peters, EM; Wanson, A, 2023) |
| "Adults with treatment-resistant depression received three IV ketamine infusions in a two-week period and were characterized as remitters or non-remitters via symptom reduction 24 h after the third infusion." | ( Achtyes, E; Ahearn, E; Frye, M; Goes, FS; Greden, J; Lapidos, A; Lopez-Vives, D; Parikh, SV; Senic, I; Sera, CE; Vande Voort, JL; Vest, E, 2023) |
| "Adults with treatment-resistant depression received three IV ketamine infusions in a two-week period and were characterized as remitters or non-remitters via symptom reduction 24 h after the third infusion." | ( Achtyes, E; Ahearn, E; Frye, M; Goes, FS; Greden, J; Lapidos, A; Lopez-Vives, D; Parikh, SV; Senic, I; Sera, CE; Vande Voort, JL; Vest, E, 2023) |
| "To evaluate the effects of ketamine treatment on depression and suicidal ideation in treatment resistant depression (TRD) and to determine whether they are influenced by other psychiatric and personality comorbidities." | ( Ahmed, GK; Ali, MA; Elfadl, GMA; Elserogy, YM; Ghada Abdelsalam, K, 2023) |
| "Ketamine treat depression by modulating the left rostral hippocampus resting-state FC with the DMN and dAN." | ( Hu, Z; Lan, X; Li, W; Liu, H; Ning, Y; Wang, C; Ye, Y; You, Z; Zhang, F; Zhou, Y, 2023) |
| "High-quality CPGs for the treatment of depression diverge regarding the definition and use of the term TRD." | ( Correia, DT; Dos Santos, IB; Dourado, A; Florez, ID; Fontes-Mota, GCH; Fráguas, R; Gabriel, FC; Melo, DO; Ribeiro, E; Rodrigues, CDS; Rodrigues, MC; Stein, AT, 2023) |
| "In total, 65 patients with treatment-resistant depression (n = 21 for ketamine 0." | ( Bai, YM; Chen, MH; Hong, CJ; Kao, CF; Li, CT; Lin, WC; Su, TP; Tsai, SJ; Tu, PC, 2023) |
| "Food and Drug Administration for treatment of depression (aripiprazole, brexpiprazole, cariprazine, extended-release quetiapine, and olanzapine-fluoxetine combination)." | ( Jha, MK; Mathew, SJ, 2023) |
| "In older adults with treatment-resistant depression, augmentation of existing antidepressants with aripiprazole improved well-being significantly more over 10 weeks than a switch to bupropion and was associated with a numerically higher incidence of remission." | ( Blumberger, DM; Brown, PJ; Cristancho, P; Flint, AJ; Gebara, MA; Gettinger, TR; Karp, JF; Lavretsky, H; Lenard, E; Lenze, EJ; Miller, JP; Mulsant, BH; Nicol, GE; Oughli, HA; Pham, VT; Reynolds, CF; Rollman, BL; Roose, SP; Yang, L, 2023) |
| "Suicide attempt is highly prevalent in treatment-resistant depression (TRD); however, the neurobiological profile of suicidal ideation versus suicide attempt is unclear." | ( Blier, P; Bouix, S; Burhunduli, P; Cho, KIK; Fang, Z; Owsia, K; Pasternak, O; Phillips, JL; Van Geel, A; Vandeloo, KL, 2023) |
| "Acupuncture is a good treatment for depression in Parkinson's disease (DPD), so the possible mechanism of acupuncture in the treatment of DPD was explored in this study." | ( Deng, Q; Deng, Y; Fu, W; Gao, J; Huang, X; Mei, J; Ning, B; Wang, Z; Wu, B; Wu, Q; Yang, Q, 2023) |
| "Rapid onset and the ability to impact treatment-resistant depression, raises the question of the best first-line medicines for patients." | ( Golani, LK; Smith, JL; Witkin, JM, 2023) |
| "For individuals with treatment-resistant depression (TRD), transcranial magnetic stimulation (TMS) has become a well-established approach." | ( Desbeaumes Jodoin, V; Elkrief, L; Garel, N; Lespérance, P; Longpré-Poirier, C; Miron, JP; Payette, O; Richard, M, 2023) |
| "SNRIs might be used as an appropriate treatment for depression-related DED." | ( Gong, L; Lin, T; Wang, W; Yin, Y; Zhao, H, 2023) |
| "Nineteen patients with treatment-resistant depression underwent two treatment sessions involving administration of psilocybin, with MRI data acquired one week prior and the day after completion of psilocybin dosing sessions." | ( Carhart-Harris, RL; Ertl, N; Kaelen, M; Lam, C; Nutt, DJ; Roseman, L; Wall, MB, 2023) |
| "Patients with treatment-resistant depression (TRD) report significant deficits in physical and mental health, as well as severely impaired health-related quality of life (HRQoL) and functioning." | ( Cooper, K; Daly, E; Drevets, WC; Jamieson, C; Popova, V; Rozjabek, HM; Singh, J, 2023) |
| "Patients with treatment-resistant depression (TRD) have higher rates of relapse and pronounced decreases in daily functioning and health-related quality of life compared to patients with major depressive disorder who are not treatment-resistant, underscoring the need for treatment choices with sustained efficacy and long-term tolerability." | ( Chen, LN; Doherty, T; Drevets, WC; Fu, DJ; Lane, R; Morrison, RL; Popova, V; Sanacora, G; Wilkinson, ST; Zaki, N, 2023) |
| "Ketamine is an emerging treatment for treatment-resistant depression (TRD) associated with rapid and robust improvements in depressive symptoms and suicidality." | ( Arekapudi, A; Chau, E; Chisamore, N; Danayan, K; Di Vincenzo, JD; Doyle, Z; Fancy, F; Kratiuk, K; Mansur, R; McIntyre, RS; Meshkat, S; Phan, L; Rodrigues, NB; Rosenblat, JD; Tabassum, A, 2023) |
| "Despite this, there are few effective treatments for BD depression, with only a handful of atypical anti-psychotics and inconsistent evidence for traditional mood stabilizing agents." | ( Chakrabarty, T; DuBois, A; Keramatian, K; Saraf, G; Yatham, LN, 2023) |
| "ZZCT has been used for the treatment of depression for centuries." | ( Chen, G; Cheng, X; Hu, Y; Qi, M; Tao, W; Xu, C; Yao, G; Yu, Y; Yue, Q; Zhao, M; Zhao, T, 2023) |
| "It has been used for the treatment of depression for more than two thousand years." | ( Deng, X; Du, Z; Fu, Q; Gao, S; Li, S; Liu, T; Ma, S; Ma, Y; Tang, R; Wang, W; Wang, X; Yu, J, 2023) |
| "Existing treatments for depression are inadequate for a significant minority of patients and new approaches are urgently needed." | ( Cowen, PJ; Harmer, CJ; Murphy, SE; Smith, ALW, 2023) |
| "MI patients with untreated depression had higher mortality than those without depression." | ( Liu, M; Lu, N; Zhang, L, 2023) |
| "The drugs currently used to treat depression have not achieved good results." | ( Gao, F; Guan, H; Li, J; Liang, J; Lu, Z; Teng, F; Tian, X; Wang, J; Wang, X, 2023) |
| "Forty-eight patients with treatment-resistant depression and strong suicidal ideation (TRD-SI) were randomly assigned to a single infusion of 0." | ( Bai, YM; Chen, MH; Li, CT; Lin, WC; Su, TP; Tsai, SJ; Tu, PC; Wu, HJ, 2023) |
| "However, the treatment of depression remains challenging largely due to blood brain barrier (BBB), which restricts drugs from entering the brain, resulting in a poor distribution of antidepressants in the brain." | ( Guan, Q; Liu, T; Lv, L; Wang, X; Yu, S, 2023) |
| "Antidepressants are used to treat acute depression in patients with bipolar I disorder, but their effect as maintenance treatment after the remission of depression has not been well studied." | ( Ahn, YM; Arumugham, SS; Ashok, MV; Beaulieu, S; Bhandary, RP; Bond, DJ; Daigneault, A; Frey, BN; Ha, K; Kesavan, M; Kondapuram, N; Lam, RW; Milev, R; Murthy, NS; Ouyang, Y; Ramachandran, K; Ravindran, A; Ravindran, N; Reddy, MS; Reddy, YCJ; Saraf, G; Schaffer, A; Wong, H; Yatham, LN, 2023) |
| "However, the mechanisms and treatments for depression in AR remain underexplored." | ( Chen, S; Cong, J; Gao, Z; Guan, M; Liu, P; Lv, H; Wang, Y; Xie, Y; Xu, Y, 2023) |
| "Prolonged treatment of depression with ketamine did not rescue depressive-like behaviour." | ( Akinluyi, ET; Edem, EE; Fafure, AA; Ikuelogbon, DA; Isaac, GT; Kunlere, OE; Nebo, KE; Oguntala, OA, 2023) |
| "The efficacy of esketamine in treatment-resistant depression (TRD) has been confirmed." | ( Advenier-Iakovlev, E; Danon, M; De Maricourt, P; Estrade, I; Gaillard, R; Gorwood, P; Leroy, S; Mancusi, RL; Mekaoui, L; Perrain, R; Petit, AC; Poupon, D; Sylvestre, V; Vinckier, F, 2023) |
| "In patients with treatment-resistant depression, esketamine nasal spray plus an SSRI or SNRI was superior to extended-release quetiapine plus an SSRI or SNRI with respect to remission at week 8." | ( Bitter, I; Buyze, J; Cebulla, K; Frey, R; Fu, DJ; Godinov, Y; Ito, T; Kambarov, Y; Llorca, PM; Messer, T; Mulhern-Haughey, S; Oliveira-Maia, AJ; Reif, A; Rive, B; von Holt, C; Young, AH, 2023) |
| "Ketamine has been recently approved to treat resistant depression; however preclinical studies showed sex differences in its efficacy." | ( García-Fuster, MJ; Jornet-Plaza, J; Ledesma-Corvi, S, 2023) |
| "Naturally occurring flavonoids treat depression via poorly understood mechanisms." | ( Ganesan, K; Gong, G; Liu, Y; Wang, J; Wang, Y; Yang, F; Zhang, Z; Zheng, Y, 2024) |