alanine has been researched along with Depression in 9 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Mice treated with PGW5 (25 and 50mg/kg/d) for 28 days did not show toxic effects in terms of weight gain and blood-chemistry analysis." | 5.40 | A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. ( Bidder, M; Gil-Ad, I; Kramer, M; Portnoy, M; Taler, M; Tarasenko, I; Weizman, A, 2014) |
| "The purpose of this study is to explore depression metabolic markers in rat hippocampus and to investigate the anti-depressant effect of genipin and its mechanisms using nuclear magnetic resonance (NMR) metabonomics." | 3.80 | [1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus]. ( Gao, S; Peng, GJ; Qin, XM; Shi, BY; Tian, JS, 2014) |
| "Cognition was assessed with the Alzheimer's Disease Assessment Scale-Cognitive (first 11 items, ADAS11)." | 1.43 | Changes in Neuropsychiatric Inventory Associated with Semagacestat Treatment of Alzheimer's Disease. ( Herrmann, N; Lanctôt, KL; Mintzer, JE; Porsteinsson, AP; Raman, R; Rosenberg, PB; Sun, X, 2016) |
| " Mice treated with PGW5 (25 and 50mg/kg/d) for 28 days did not show toxic effects in terms of weight gain and blood-chemistry analysis." | 1.40 | A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. ( Bidder, M; Gil-Ad, I; Kramer, M; Portnoy, M; Taler, M; Tarasenko, I; Weizman, A, 2014) |
| "Depression was measured with brief 23-item Geriatrics Depression Scale Chinese-edition (GDS-CD)." | 1.35 | Pro12Ala polymorphism in PPARgamma2 associated with depression in Chinese nonagenarians/centenarians. ( Bi-Rong, D; Chang-Quan, H; Hong-Mei, W; Ji-Rong, Y; Mattis, TA; Yan-Ling, Z; Zhen-Chan, L, 2009) |
| "Depression is characterized by a lack of "motivation" rather than a lack of "physical space" to move around." | 1.32 | Open space swimming test to index antidepressant activity. ( Alkon, DL; Sun, MK, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, L | 1 |
| Zheng, X | 1 |
| Wang, S | 1 |
| Tang, C | 1 |
| Zhang, Y | 1 |
| Yao, G | 1 |
| Zeng, J | 1 |
| Ge, S | 1 |
| Wen, H | 1 |
| Xu, M | 1 |
| Guyatt, G | 1 |
| Xu, N | 1 |
| Gil-Ad, I | 1 |
| Portnoy, M | 1 |
| Tarasenko, I | 1 |
| Bidder, M | 1 |
| Kramer, M | 1 |
| Taler, M | 1 |
| Weizman, A | 1 |
| Peng, GJ | 1 |
| Shi, BY | 1 |
| Tian, JS | 1 |
| Gao, S | 1 |
| Qin, XM | 1 |
| Rosenberg, PB | 1 |
| Lanctôt, KL | 1 |
| Herrmann, N | 1 |
| Mintzer, JE | 1 |
| Porsteinsson, AP | 1 |
| Sun, X | 1 |
| Raman, R | 1 |
| Costa, B | 1 |
| Pini, S | 1 |
| Martini, C | 1 |
| Abelli, M | 1 |
| Gabelloni, P | 1 |
| Landi, S | 1 |
| Muti, M | 1 |
| Gesi, C | 1 |
| Lari, L | 1 |
| Cardini, A | 1 |
| Galderisi, S | 1 |
| Mucci, A | 1 |
| Lucacchini, A | 1 |
| Cassano, GB | 1 |
| Ji-Rong, Y | 1 |
| Bi-Rong, D | 1 |
| Chang-Quan, H | 1 |
| Zhen-Chan, L | 1 |
| Hong-Mei, W | 1 |
| Yan-Ling, Z | 1 |
| Mattis, TA | 1 |
| Gałecki, P | 1 |
| Smigielski, J | 1 |
| Florkowski, A | 1 |
| Bobińska, K | 1 |
| Pietras, T | 1 |
| Szemraj, J | 1 |
| Sun, MK | 1 |
| Alkon, DL | 1 |
| Papassotiropoulos, A | 1 |
| Bagli, M | 1 |
| Feder, O | 1 |
| Jessen, F | 1 |
| Maier, W | 1 |
| Rao, ML | 1 |
| Ludwig, M | 1 |
| Schwab, SG | 1 |
| Heun, R | 1 |
1 review available for alanine and Depression
| Article | Year |
|---|---|
Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis.
Topics: Acitretin; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Antibodies, Monoclonal, Humanized; Anx | 2020 |
8 other studies available for alanine and Depression
| Article | Year |
|---|---|
A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia.
Topics: Alanine; Amphetamine; Animals; Antipsychotic Agents; Anxiety; Benzodiazepines; Brain; Central Nervou | 2014 |
[1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus].
Topics: Alanine; Animals; Antidepressive Agents; Aspartic Acid; Behavior, Animal; Chronic Disease; Depressio | 2014 |
Changes in Neuropsychiatric Inventory Associated with Semagacestat Treatment of Alzheimer's Disease.
Topics: Aged; Alanine; Alzheimer Disease; Amyloid Precursor Protein Secretases; Apathy; Appetite; Azepines; | 2016 |
Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression.
Topics: Adult; Alanine; Amino Acid Substitution; Anxiety, Separation; Depression; Female; Genetic Predisposi | 2009 |
Pro12Ala polymorphism in PPARgamma2 associated with depression in Chinese nonagenarians/centenarians.
Topics: Aged, 80 and over; Alanine; China; Depression; Female; Gene Frequency; Humans; Logistic Models; Male | 2009 |
Analysis of two polymorphisms of the manganese superoxide dismutase gene (Ile-58Thr and Ala-9Val) in patients with recurrent depressive disorder.
Topics: Alanine; Amino Acids; Case-Control Studies; Depression; Female; Gene Frequency; Genetic Predispositi | 2010 |
Open space swimming test to index antidepressant activity.
Topics: Alanine; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Drug | 2003 |
Genetic polymorphism of cathepsin D is strongly associated with the risk for developing sporadic Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alanine; Alzheimer Disease; Amino Acid Substitution; Apolipoprotein E4; Apo | 1999 |