dehydroepiandrosterone has been researched along with Depression in 88 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The associations between endogenous dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS), and depression in older women are uncertain." | 9.41 | Endogenous dehydroepiandrosterone and depression in postmenopausal women: a systematic review of observational studies. ( Bell, RJ; Davis, SR; Hemachandra, C; Islam, RM; Sultana, F, 2023) |
| "Dehydroepiandrosterone (DHEA) has been reported to improve fatigue and reduced well-being." | 9.14 | Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial. ( Bijl, M; Bijlsma, JW; Derksen, RH; Geenen, R; Godaert, GL; Hartkamp, A, 2010) |
| "Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) age-related withdrawal is very likely to be involved in the aging process and the onset of age-related diseases, giving rise to the question of whether preventing or compensating the decline of these steroids may have endocrine and clinical benefits." | 9.11 | Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency. ( Bernardi, F; Genazzani, AD; Genazzani, AR; Inglese, S; Lombardi, I; Luisi, M; Pieri, M; Rovati, L, 2004) |
| "Dehydroepiandrosterone improves well-being and sexuality in women with adrenal insufficiency." | 9.09 | Dehydroepiandrosterone replacement in women with adrenal insufficiency. ( Allolio, B; Arlt, W; Bidlingmaier, M; Callies, F; Ernst, M; Huebler, D; Koehler, I; Oettel, M; Reincke, M; Schulte, HM; van Vlijmen, JC, 1999) |
| "An electronic search was carried out using the keywords Dehydroepiandrosterone (Mesh) AND Depression (Mesh) in the following databases: Medical Literature databases Analysis and Retrieval System Online (Medline), Excerpta Medical Database (EMBASE), Latin American and Caribbean Health Sciences (LILACS) and the Cochrane Library through their website for relevant publications until June 2018." | 8.98 | Dehydroepiandrosterone (DHEA) for Depression: A Systematic Review and Meta-Analysis. ( Cardoso, A; Grande, AJ; Mallmann, MB; Nardi, AE; Peixoto, C; Veras, AB, 2018) |
| " We measured severity of depression with Beck's Depression Inventory (BDI) and Hamilton's Depression Rating Scale (HDRS), plasma concentrations of cortisol, DHEA and DHEA-S, and CSF concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA), the norepinephrine metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG) and the dopamine metabolite homovanillic acid (HVA) in 21 abstinent alcoholics after 4 weeks of abstinence and in 11 age-matched healthy control subjects." | 7.70 | Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations. ( George, D; Heinz, A; Hommer, D; Linnoila, M; Weingartner, H; Wolkowitz, OM, 1999) |
| "These findings suggest that DHEA treatment induced depression-like behavior in PCOS mice, possibly through down-regulation of brain monoamines and/or their metabolites, which implies the contribution of hyperandrogenism to the psychological symptoms of women with PCOS." | 5.43 | Depression-Like Behavior in a Dehydroepiandrosterone-Induced Mouse Model of Polycystic Ovary Syndrome. ( Hao, S; Kang, J; Shen, Q; Song, X; Wang, H; Yu, Q, 2016) |
| "The associations between endogenous dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS), and depression in older women are uncertain." | 5.41 | Endogenous dehydroepiandrosterone and depression in postmenopausal women: a systematic review of observational studies. ( Bell, RJ; Davis, SR; Hemachandra, C; Islam, RM; Sultana, F, 2023) |
| "Depression was assessed using Beck Depression Inventory (BDI) and defined as BDI > or =16 points." | 5.36 | Deficiencies in circulating testosterone and dehydroepiandrosterone sulphate, and depression in men with systolic chronic heart failure. ( Banasiak, W; Borodulin-Nadzieja, L; Drohomirecka, A; Jankowska, EA; Lopuszanska, M; Ponikowska, B; Ponikowski, P; Poole-Wilson, PA; Szklarska, A; Witkowska, A, 2010) |
| "The 3α,5α- and 3α,5β-reduced metabolites of progesterone, deoxycorticosterone, and dehydroepiandrosterone (DHEA) have potent effects on neurotransmission mediated by GABA(A) receptors, and dysregulation of these receptors has been implicated in depression." | 5.16 | A history of depression in women is associated with an altered GABAergic neuroactive steroid profile. ( Girdler, SS; Johnson, JL; Lindgren, M; Morrow, AL; Porcu, P; Rubinow, DR, 2012) |
| "Dehydroepiandrosterone (DHEA) has been reported to improve fatigue and reduced well-being." | 5.14 | Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial. ( Bijl, M; Bijlsma, JW; Derksen, RH; Geenen, R; Godaert, GL; Hartkamp, A, 2010) |
| "Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) age-related withdrawal is very likely to be involved in the aging process and the onset of age-related diseases, giving rise to the question of whether preventing or compensating the decline of these steroids may have endocrine and clinical benefits." | 5.11 | Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency. ( Bernardi, F; Genazzani, AD; Genazzani, AR; Inglese, S; Lombardi, I; Luisi, M; Pieri, M; Rovati, L, 2004) |
| "Dehydroepiandrosterone improves well-being and sexuality in women with adrenal insufficiency." | 5.09 | Dehydroepiandrosterone replacement in women with adrenal insufficiency. ( Allolio, B; Arlt, W; Bidlingmaier, M; Callies, F; Ernst, M; Huebler, D; Koehler, I; Oettel, M; Reincke, M; Schulte, HM; van Vlijmen, JC, 1999) |
| " This paper reviews the scientific literature published between 1990 and 2000 investigating the effects of oestrogen, testosterone and dehydroepiandrosterone (DHEA) on depression and dementia." | 4.81 | Sex hormones and their impact on dementia and depression: a clinical perspective. ( Almeida, OP; Barclay, L, 2001) |
| "The purpose of this prospective study was to investigate the effect of nonsurgical periodontal treatment (PT) on anxiety/depression scale scores and on gingival crevicular fluid (GCF) cortisol (COR) and dehydroepiandrosterone (DHEA) levels." | 3.91 | The effect of nonsurgical periodontal treatment on gingival crevicular fluid stress hormone levels: A prospective study. ( Alkan, BA; Cakmak, O; Saatci, E; Tasdemir, Z, 2019) |
| "The following variables were analyzed: passive and stimulated saliva flow, stress levels and phase, depression, anxiety, serum cortisol and dehydroepiandrosterone (DHEA) levels, and the presence of polymorphisms in the interleukin 6 (IL-6) gene." | 3.83 | Comparative Analysis of Psychological, Hormonal, and Genetic Factors Between Burning Mouth Syndrome and Secondary Oral Burning. ( AraújoMouraLemos, TM; Barbosa, NG; da Silveira, EJ; das Neves de Araújo Lima, E; de Medeiros, AM; de Souza, CM; Dos Santos, AC; Trevilatto, PC, 2016) |
| "Major depression have been associated with cortisol and dehydroepiandrosterone (DHEA) changes in old depressed patients." | 3.83 | Cortisol, DHEA, and depression in the elderly: the influence of physical capacity. ( Corrêa, H; Deslandes, A; Laks, J; Maciel-Pinheiro, Pde T; Moraes, H, 2016) |
| "The aim of this study was to determine the salivary levels of dehydroepiandrosterone (DHEA) and cortisol and scores of depression, anxiety and stress in patients with oral lichen planus (OLP)." | 3.77 | Salivary cortisol and dehydroepiandrosterone (DHEA) levels, psychological factors in patients with oral lichen planus. ( Cherubini, K; de Figueiredo, MA; Girardi, C; Luz, C; Nunes, ML; Salum, FG, 2011) |
| " The purpose of this study was to investigate the motor function, anxiety levels, depression-related emotional responses, attentional function and plasma levels of testosterone and dehydroepiandrosterone (DHEA) in SAMP10." | 3.76 | Depression-like behavior and reduced plasma testosterone levels in the senescence-accelerated mouse. ( Egashira, N; Fujiwara, M; Iwasaki, K; Koushi, E; Mishima, K; Oishi, R; Okuno, R; Shirakawa, A, 2010) |
| " The secondary objectives were as follows: to describe demographic and clinical characteristics of male patients with FM; to evaluate basal levels of dehydroepiandrosterone sulfate (DHEAS) and total testosterone in both groups; and to investigate the relationship among pain, tender points, anxiety, and depression in these patients." | 3.76 | A comparison of quality of life, demographic and clinical characteristics of Brazilian men with fibromyalgia syndrome with male patients with depression. ( Helfenstein, M; Heymann, RE; Pollak, DF; Yoshikawa, GT, 2010) |
| "This study was conducted to evaluate salivary dehydroepiandrosterone (DHEA) levels, salivary flow rate (SFR), depression, and hopelessness in patients with the complaint of burning mouth (BM)." | 3.75 | Salivary dehydroepiandrosterone (DHEA) levels in patients with the complaint of burning mouth: a case-control study. ( Bandeira, D; Cherubini, K; Dias Fernandes, CS; Luz, C; Pawlowski, J; Salum, FG, 2009) |
| " Fifteen non-CNS-SLE patients, 15 RA patients and 15 HC participants similar in age, education, and gender (female) were compared on tests of cognition, depression, and plasma levels of interleukin-6 (IL-6), dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S) and cortisol." | 3.71 | Inflammatory and hormonal measures predict neuropsychological functioning in systemic lupus erythematosus and rheumatoid arthritis patients. ( Kozora, E; Laudenslager, M; Lemieux, A; West, SG, 2001) |
| " We measured severity of depression with Beck's Depression Inventory (BDI) and Hamilton's Depression Rating Scale (HDRS), plasma concentrations of cortisol, DHEA and DHEA-S, and CSF concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA), the norepinephrine metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG) and the dopamine metabolite homovanillic acid (HVA) in 21 abstinent alcoholics after 4 weeks of abstinence and in 11 age-matched healthy control subjects." | 3.70 | Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations. ( George, D; Heinz, A; Hommer, D; Linnoila, M; Weingartner, H; Wolkowitz, OM, 1999) |
| "iv) The description of chronic fatigue syndrome as regards the endocrinological, epidemiological and psychiatric characteristics are in good agreement with our experience on patients having interstitial pneumonia, evidence in support of our proposal that there is no convincing reasoning to separate chronic fatigue syndrome from interstitial pneumonia." | 2.71 | The clinical course of interstitial pneumonia alias chronic fatigue syndrome under the control of megadose vitamin C infusion system with dehydroepiandrosterone-cortisol annex. ( Kodama, M; Kodama, T, 2005) |
| "Depression is a mental disorder that affects millions of people around the world." | 2.66 | Dehydroepiandrosterone for depressive symptoms: A systematic review and meta-analysis of randomized controlled trials. ( Barciela Veras, A; Cardoso, A; Gomes Carrilho, C; José Grande, A; Nardi, AE; Peixoto, C, 2020) |
| "Dehydroepiandrosterone (DHEA) has been studied as an agent to improve HRQOL in these patients." | 2.45 | A systematic review and meta-analysis of randomized placebo-controlled trials of DHEA treatment effects on quality of life in women with adrenal insufficiency. ( Alkatib, AA; Cosma, M; Elamin, MB; Erickson, D; Erwin, PJ; Montori, VM; Swiglo, BA, 2009) |
| "Depression was assessed using the Mood and Feelings Questionnaire (MFQ) and clinical interview." | 1.48 | The association between pubertal status and depressive symptoms and diagnoses in adolescent females: A population-based cohort study. ( Goodyer, I; Ioannidis, K; Jones, PB; Lewis, G; Neufeld, S; Stochl, J; van Harmelen, AL, 2018) |
| "These findings suggest that DHEA treatment induced depression-like behavior in PCOS mice, possibly through down-regulation of brain monoamines and/or their metabolites, which implies the contribution of hyperandrogenism to the psychological symptoms of women with PCOS." | 1.43 | Depression-Like Behavior in a Dehydroepiandrosterone-Induced Mouse Model of Polycystic Ovary Syndrome. ( Hao, S; Kang, J; Shen, Q; Song, X; Wang, H; Yu, Q, 2016) |
| "Patients with temporomandibular disorders (TMD) commonly experience myofascial and joint pain, pain-related disability, and other pain conditions including depression." | 1.43 | Association of pain intensity, pain-related disability, and depression with hypothalamus-pituitary-adrenal axis function in female patients with chronic temporomandibular disorders. ( Ahn, RS; Jo, KB; Lee, IG; Lee, SC; Lee, YJ; Park, JY, 2016) |
| "Posttraumatic stress disorder (PTSD) is associated with increased morbidity and mortality through somatic conditions, particularly cardiovascular disease." | 1.42 | Altered one-carbon metabolism in posttraumatic stress disorder. ( Assies, J; de Vries, GJ; Lok, A; Mocking, R; Olff, M; Schene, A, 2015) |
| "Patients with chronic periodontitis (CP) and those with healthy periodontal tissues/mild gingivitis were included." | 1.40 | Association of gingival crevicular fluid cortisol/dehydroepiandrosterone levels with periodontal status. ( Abdulrezzak, U; Alkan, BA; Cakmak, O; Ozsoy, S; Sen, A, 2014) |
| "Both the event of rape and PTSD diagnosis, and not factors such as sleep duration, smoking, education or oral contraceptives, accounted for the neuroendocrine differences between rape victims and controls." | 1.39 | Salivary cortisol and dehydroepiandrosterone sulfate in adolescent rape victims with post traumatic stress disorder. ( Bicanic, IA; De Roos, C; Olff, M; Postma, RM; Sinnema, G; Van de Putte, EM; Van Wesel, F, 2013) |
| "Depression was assessed using Beck Depression Inventory (BDI) and defined as BDI > or =16 points." | 1.36 | Deficiencies in circulating testosterone and dehydroepiandrosterone sulphate, and depression in men with systolic chronic heart failure. ( Banasiak, W; Borodulin-Nadzieja, L; Drohomirecka, A; Jankowska, EA; Lopuszanska, M; Ponikowska, B; Ponikowski, P; Poole-Wilson, PA; Szklarska, A; Witkowska, A, 2010) |
| "Previous research suggests that in borderline personality disorder (BPD) normal stress regulation, with a main role for cortisol, is disturbed." | 1.34 | Basal cortisol and DHEA levels in women with borderline personality disorder. ( de Knijff, DW; Jogems-Kosterman, BJ; Kusters, R; van Hoof, JJ, 2007) |
| "Depressive symptoms, smoking withdrawal symptoms, and plasma steroid levels were measured before and after 8 days of verified smoking abstinence." | 1.33 | A decrease in the plasma DHEA to cortisol ratio during smoking abstinence may predict relapse: a preliminary study. ( Anderson, GM; Krishnan-Sarin, S; Paliwal, P; Rasmusson, AM; Wu, R, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (3.41) | 18.7374 |
| 1990's | 11 (12.50) | 18.2507 |
| 2000's | 30 (34.09) | 29.6817 |
| 2010's | 36 (40.91) | 24.3611 |
| 2020's | 8 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Hatipoglu, E | 1 |
| Hacioglu, Y | 1 |
| Polat, Y | 1 |
| Arslan, HF | 1 |
| Oner, S | 1 |
| Ekmekci, OB | 1 |
| Niyazoglu, M | 1 |
| Hemachandra, C | 1 |
| Davis, SR | 1 |
| Bell, RJ | 1 |
| Sultana, F | 1 |
| Islam, RM | 1 |
| Agorastos, A | 1 |
| Heinig, A | 1 |
| Sommer, A | 1 |
| Wiedemann, K | 1 |
| Demiralay, C | 1 |
| Pang, RD | 1 |
| Tucker, CJ | 1 |
| Guillot, CR | 1 |
| Belcher, B | 1 |
| Kirkpatrick, MG | 1 |
| Micol, VJ | 1 |
| Roberts, AG | 1 |
| Taylor-Cavelier, SJ | 1 |
| Geiss, EG | 1 |
| Lopez-Duran, N | 1 |
| Froger, N | 1 |
| Mukerji, SS | 1 |
| Misra, V | 1 |
| Lorenz, DR | 1 |
| Chettimada, S | 1 |
| Keller, K | 1 |
| Letendre, S | 1 |
| Ellis, RJ | 1 |
| Morgello, S | 1 |
| Parker, RA | 1 |
| Gabuzda, D | 1 |
| Alghadir, AH | 1 |
| Gabr, SA | 1 |
| Peixoto, C | 3 |
| José Grande, A | 1 |
| Gomes Carrilho, C | 1 |
| Nardi, AE | 3 |
| Cardoso, A | 3 |
| Barciela Veras, A | 1 |
| Chronister, BN | 1 |
| Gonzalez, E | 1 |
| Lopez-Paredes, D | 1 |
| Suarez-Torres, J | 1 |
| Gahagan, S | 1 |
| Martinez, D | 1 |
| Barros, J | 1 |
| Jacobs, DR | 1 |
| Checkoway, H | 1 |
| Suarez-Lopez, JR | 1 |
| Kent, M | 1 |
| Bardi, M | 2 |
| Hazelgrove, A | 1 |
| Sewell, K | 1 |
| Kirk, E | 1 |
| Thompson, B | 1 |
| Trexler, K | 1 |
| Terhune-Cotter, B | 1 |
| Lambert, K | 1 |
| Samardzic, J | 1 |
| Hencic, B | 1 |
| Jancic, J | 1 |
| Jadzic, D | 1 |
| Djuric, M | 1 |
| Obradovic, DI | 1 |
| Svob Strac, D | 1 |
| Hassan, K | 1 |
| Elimeleh, Y | 1 |
| Shehadeh, M | 1 |
| Hassan, F | 1 |
| Rubinchik, I | 1 |
| Lewis, G | 2 |
| Ioannidis, K | 1 |
| van Harmelen, AL | 1 |
| Neufeld, S | 1 |
| Stochl, J | 1 |
| Jones, PB | 1 |
| Goodyer, I | 1 |
| Ng, KST | 1 |
| Sia, A | 1 |
| Ng, MKW | 1 |
| Tan, CTY | 1 |
| Chan, HY | 1 |
| Tan, CH | 1 |
| Rawtaer, I | 1 |
| Feng, L | 1 |
| Mahendran, R | 1 |
| Larbi, A | 1 |
| Kua, EH | 1 |
| Ho, RCM | 1 |
| Grande, AJ | 1 |
| Mallmann, MB | 1 |
| Veras, AB | 2 |
| Cakmak, O | 2 |
| Alkan, BA | 2 |
| Saatci, E | 1 |
| Tasdemir, Z | 1 |
| Ellis, R | 1 |
| Fernandes, A | 1 |
| Simmons, JG | 2 |
| Mundy, L | 1 |
| Patton, G | 1 |
| Allen, NB | 2 |
| Whittle, S | 2 |
| Walther, A | 2 |
| Tsao, C | 1 |
| Pande, R | 1 |
| Kirschbaum, C | 1 |
| Field, E | 1 |
| Berkman, L | 1 |
| Moriguchi, S | 1 |
| Shinoda, Y | 1 |
| Yamamoto, Y | 1 |
| Sasaki, Y | 1 |
| Miyajima, K | 1 |
| Tagashira, H | 1 |
| Fukunaga, K | 1 |
| Duggal, NA | 1 |
| Beswetherick, A | 1 |
| Upton, J | 1 |
| Hampson, P | 1 |
| Phillips, AC | 1 |
| Lord, JM | 1 |
| Ozsoy, S | 1 |
| Sen, A | 1 |
| Abdulrezzak, U | 1 |
| Pluchino, N | 1 |
| Drakopoulos, P | 1 |
| Bianchi-Demicheli, F | 1 |
| Wenger, JM | 1 |
| Petignat, P | 1 |
| Genazzani, AR | 2 |
| Devicari Cheda, JN | 1 |
| de Vries, GJ | 1 |
| Lok, A | 1 |
| Mocking, R | 1 |
| Assies, J | 1 |
| Schene, A | 1 |
| Olff, M | 2 |
| Rabijewski, M | 1 |
| Papierska, L | 1 |
| Kuczerowski, R | 1 |
| Piątkiewicz, P | 1 |
| Delany, FM | 1 |
| Byrne, ML | 1 |
| Olsson, C | 1 |
| Mundy, LK | 1 |
| Patton, GC | 1 |
| das Neves de Araújo Lima, E | 1 |
| Barbosa, NG | 1 |
| Dos Santos, AC | 1 |
| AraújoMouraLemos, TM | 1 |
| de Souza, CM | 1 |
| Trevilatto, PC | 1 |
| da Silveira, EJ | 1 |
| de Medeiros, AM | 1 |
| Jo, KB | 1 |
| Lee, YJ | 1 |
| Lee, IG | 1 |
| Lee, SC | 1 |
| Park, JY | 1 |
| Ahn, RS | 1 |
| Kobayashi, M | 1 |
| Sugiyama, N | 1 |
| Sasayama, D | 1 |
| Sasamoto, H | 1 |
| Miyashiro, Y | 1 |
| Arima, K | 1 |
| Washizuka, S | 1 |
| Moraes, H | 1 |
| Deslandes, A | 1 |
| Maciel-Pinheiro, Pde T | 1 |
| Corrêa, H | 1 |
| Laks, J | 1 |
| Yu, Q | 1 |
| Hao, S | 1 |
| Wang, H | 1 |
| Song, X | 1 |
| Shen, Q | 1 |
| Kang, J | 1 |
| Philipp, M | 1 |
| Lozza, N | 1 |
| Ehlert, U | 1 |
| Šrámková, M | 1 |
| Dušková, M | 1 |
| Hill, M | 1 |
| Bičíková, M | 1 |
| Řípová, D | 1 |
| Mohr, P | 1 |
| Stárka, L | 1 |
| Maninger, N | 1 |
| Wolkowitz, OM | 3 |
| Reus, VI | 2 |
| Epel, ES | 1 |
| Mellon, SH | 1 |
| Yoshikawa, GT | 1 |
| Heymann, RE | 1 |
| Helfenstein, M | 1 |
| Pollak, DF | 1 |
| Alkatib, AA | 1 |
| Cosma, M | 1 |
| Elamin, MB | 1 |
| Erickson, D | 1 |
| Swiglo, BA | 1 |
| Erwin, PJ | 1 |
| Montori, VM | 1 |
| Dias Fernandes, CS | 1 |
| Salum, FG | 2 |
| Bandeira, D | 1 |
| Pawlowski, J | 1 |
| Luz, C | 2 |
| Cherubini, K | 2 |
| Hartkamp, A | 1 |
| Geenen, R | 1 |
| Godaert, GL | 1 |
| Bijl, M | 1 |
| Bijlsma, JW | 1 |
| Derksen, RH | 1 |
| Egashira, N | 1 |
| Koushi, E | 1 |
| Okuno, R | 1 |
| Shirakawa, A | 1 |
| Mishima, K | 1 |
| Iwasaki, K | 1 |
| Oishi, R | 1 |
| Fujiwara, M | 1 |
| Jankowska, EA | 1 |
| Drohomirecka, A | 1 |
| Ponikowska, B | 1 |
| Witkowska, A | 1 |
| Lopuszanska, M | 1 |
| Szklarska, A | 1 |
| Borodulin-Nadzieja, L | 1 |
| Banasiak, W | 1 |
| Poole-Wilson, PA | 1 |
| Ponikowski, P | 1 |
| Girardi, C | 1 |
| de Figueiredo, MA | 1 |
| Nunes, ML | 1 |
| Girdler, SS | 1 |
| Lindgren, M | 1 |
| Porcu, P | 1 |
| Rubinow, DR | 1 |
| Johnson, JL | 1 |
| Morrow, AL | 1 |
| Traish, AM | 1 |
| Kang, HP | 1 |
| Saad, F | 1 |
| Guay, AT | 1 |
| Rhone, AP | 1 |
| Franssen, CL | 1 |
| Hampton, JE | 1 |
| Shea, EA | 1 |
| Hyer, MM | 1 |
| Huber, J | 1 |
| Lambert, KG | 1 |
| Colangelo, LA | 1 |
| Craft, LL | 1 |
| Ouyang, P | 1 |
| Liu, K | 1 |
| Schreiner, PJ | 1 |
| Michos, ED | 1 |
| Gapstur, SM | 1 |
| Bicanic, IA | 1 |
| Postma, RM | 1 |
| Sinnema, G | 1 |
| De Roos, C | 1 |
| Van Wesel, F | 1 |
| Van de Putte, EM | 1 |
| Schmidt, PJ | 1 |
| Murphy, JH | 1 |
| Haq, N | 1 |
| Danaceau, MA | 1 |
| St Clair, L | 1 |
| Hyyppä, MT | 1 |
| Kronholm, E | 1 |
| Virtanen, A | 1 |
| Leino, A | 1 |
| Jula, A | 1 |
| Angold, A | 1 |
| Nadjafi-Triebsch, C | 1 |
| Huell, M | 1 |
| Burki, D | 1 |
| Rohr, UD | 1 |
| Patel, BN | 1 |
| Pang, D | 1 |
| Stern, Y | 1 |
| Silverman, W | 1 |
| Kline, JK | 1 |
| Mayeux, R | 1 |
| Schupf, N | 1 |
| Pico-Alfonso, MA | 1 |
| Garcia-Linares, MI | 1 |
| Celda-Navarro, N | 1 |
| Herbert, J | 1 |
| Martinez, M | 1 |
| Kodama, M | 1 |
| Kodama, T | 1 |
| Inglese, S | 1 |
| Lombardi, I | 1 |
| Pieri, M | 1 |
| Bernardi, F | 1 |
| Genazzani, AD | 1 |
| Rovati, L | 1 |
| Luisi, M | 1 |
| Maayan, R | 3 |
| Morad, O | 1 |
| Dorfman, P | 1 |
| Overstreet, DH | 1 |
| Weizman, A | 3 |
| Yadid, G | 2 |
| Eser, D | 1 |
| Schüle, C | 1 |
| Romeo, E | 1 |
| Baghai, TC | 1 |
| di Michele, F | 1 |
| Pasini, A | 1 |
| Zwanzger, P | 1 |
| Padberg, F | 1 |
| Rupprecht, R | 1 |
| Ryff, CD | 1 |
| Dienberg Love, G | 1 |
| Urry, HL | 1 |
| Muller, D | 1 |
| Rosenkranz, MA | 1 |
| Friedman, EM | 1 |
| Davidson, RJ | 1 |
| Singer, B | 1 |
| Rasmusson, AM | 1 |
| Wu, R | 1 |
| Paliwal, P | 1 |
| Anderson, GM | 1 |
| Krishnan-Sarin, S | 1 |
| Shamlian, NT | 1 |
| Cole, MG | 1 |
| Jogems-Kosterman, BJ | 1 |
| de Knijff, DW | 1 |
| Kusters, R | 1 |
| van Hoof, JJ | 1 |
| Touati-Werner, D | 1 |
| Ram, E | 1 |
| Strous, R | 1 |
| Keren, O | 1 |
| Goldman, N | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| In Vivo Targeting of Neuroactive Steroid and Immune Networks for Depression in People Living With HIV[NCT05570812] | Phase 2 | 120 participants (Anticipated) | Interventional | 2023-03-03 | Recruiting | ||
| The Effect Of Horticultural Therapy On The Level Of Happiness And Loneliness Of Elderly Living In Nursing Home[NCT04291183] | 50 participants (Anticipated) | Interventional | 2020-03-11 | Not yet recruiting | |||
| Pilot Evaluation of Technology-enhanced Horticultural Activities Among the People With Dementia and Their Family Caregivers[NCT05577975] | 60 participants (Anticipated) | Interventional | 2022-09-01 | Recruiting | |||
| Relationship Between Central Sensitization and Alteration of Circulating Neurosteroid Following Bilateral Total Knee Arthroplasty[NCT03298711] | 69 participants (Actual) | Observational | 2017-11-20 | Completed | |||
| The Interplay Between Addiction to Tobacco Smoking and Sleep Quality Among Healthy Adults[NCT04265339] | 150 participants (Anticipated) | Interventional | 2018-10-15 | Recruiting | |||
| Fatigue and General Well-Being in Patients With Systemic Lupus Erythematosus or Primary Sjögren's Syndrome: Effects of Dehydroepiandrosterone Administration[NCT00391924] | Phase 2 | 120 participants | Interventional | 2000-05-31 | Completed | ||
| The Effect of a Higher Dose of Dehydroepiandrosterone (DHEA) Supplementation on the Number of Oocytes Obtained During IVF in Poor Ovarian Responders[NCT02357472] | Phase 4 | 50 participants (Anticipated) | Interventional | 2014-12-31 | Active, not recruiting | ||
| Effectiveness of Prazosin in Bulimic Patients Experiencing Nightmares Due to PTSD[NCT02382848] | 9 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Longitudinal Measurement of Cortisol in Association With Mental Health and Experience of Domestic Violence and Abuse[NCT01632553] | 214 participants (Actual) | Observational | 2012-08-31 | Completed | |||
| Effects of Omega-3 Fatty Acids on Bone and Frailty[NCT00634686] | Phase 4 | 150 participants (Anticipated) | Interventional | 2007-01-31 | Active, not recruiting | ||
| Dehydroepiandrosterone(DHEA) Substitution in Adolescent and Young Women With Central Adrenal Insufficiency. A Multicenter, Randomised Double Blind Trial[NCT00575341] | Phase 3 | 23 participants (Actual) | Interventional | 2003-10-31 | Completed | ||
| Early Mental Response to Hormonal Treatment in Transgender Men - The EMRE Study[NCT05649605] | 70 participants (Anticipated) | Interventional | 2023-03-07 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
EDI-3 (Eating Disorder Inventory 3 Scale) is a pencil and paper test consisting of 91 items and 12 sub-scales. The main scales are the drive for thinness and the bulimia scales, the remaining sub-scales are: low self-esteem, body dissatisfaction, maturity fears, personal alienation, interpersonal alienation, interpersonal insecurity, perfectionism, interoceptive deficits, emotional dysregulation, and asceticism. The response options are based on a 6-point Likert-type scale are: Always, Usually, Often, Sometimes, Rarely, and Never. There are six composite scores, 12 primary scores, and three response style validity indicators. Software is used to calculate the raw scores, composite scores, validity scale scores and the T-scores. The t-score for the Bulimia scale will be used for this analysis with a range of 22-66. Higher scores indicate the likelihood of an eating disorder. A higher t-score on the bulimia scale indicates a worse outcome. (NCT02382848)
Timeframe: 3 weeks
| Intervention | T-Score (Mean) |
|---|---|
| Prazosin | 43.1 |
| Placebo | 38.6 |
Rating scales and subject interview will be used to determine if there is a decrease in depressed mood among participants undergoing drug intervention. The HDRS (Hamilton Depression Rating Scale) consists of 17 items, some scored on a 5-point scale (0-4) and others scored on a 3-point scale (0-2). Items from the scale can be summed to give a total score ranging from 0 to 50, with higher scores indicating a worse outcome. This analysis is based on a single item from the scale (Depressed Mood, measured on a 5-point scale) where a higher score again indicates a worse outcome. (NCT02382848)
Timeframe: 3 weeks
| Intervention | score on a scale (Mean) |
|---|---|
| Prazosin | 1.4 |
| Placebo | 1.3 |
"The individual question about frightening dreams from the Nightmares Subscale of a self-administered questionnaire (Sleep-50 Questionnaire), will be used to determine if there is a decrease in frequency of nightmares in patients undergoing drug intervention. For each question, respondents are provided with a scale ranging from 1 (not at all) to 4 (very much) and are asked to indicate the extent to which the statement has matched their experience over the study time frame. The scale values range from 1-4, where a lower value indicates lower frequency of nightmares. A higher score is a worse outcome." (NCT02382848)
Timeframe: 3 weeks
| Intervention | score on a scale (Mean) |
|---|---|
| Prazosin | 2.25 |
| Placebo | 2.75 |
Rating scales and subject interview will be used to determine if there is a decrease in self harm among participants undergoing drug intervention. The HDRS (Hamilton Depression Rating Scale) consists of 17 items, some scored on a 5-point scale (0-4) and others scored on a 3-point scale (0-2). Items from the scale can be summed to give a total score ranging from 0 to 50, with higher scores indicating a worse outcome. This analysis is based on a single item from the scale (Self Harm, measured on a 5-point scale) where a higher score again indicates a worse outcome. (NCT02382848)
Timeframe: 3 weeks
| Intervention | score on a scale (Mean) |
|---|---|
| Prazosin | 0.5 |
| Placebo | .1 |
The CAPS (Clinician administered PTSD) rating scale consists of 30 questions rated on a 0-4 point scoring system and patient interview will be used to determine if there is a decrease in PTSD Symptoms among participants undergoing drug intervention. 17 of these questions are used to calculate the total severity score used in this analysis. This is done by summing the frequency and intensity ratings (each ranging from 0-4) for each of the 17 questions. The total severity score can have a range of 0-136. A higher score on this scale indicates a worse outcome. (NCT02382848)
Timeframe: 3 weeks
| Intervention | score on a scale (Mean) |
|---|---|
| Prazosin | 65.5 |
| Placebo | 79.8 |
12 reviews available for dehydroepiandrosterone and Depression
| Article | Year |
|---|---|
Endogenous dehydroepiandrosterone and depression in postmenopausal women: a systematic review of observational studies.
Topics: Affect; Aged; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; Female; Humans; Ob | 2023 |
[New therapeutic avenues for neurosteroids in psychiatric diseases].
Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; Drugs, Investigational; | 2019 |
Dehydroepiandrosterone for depressive symptoms: A systematic review and meta-analysis of randomized controlled trials.
Topics: Adjuvants, Immunologic; Dehydroepiandrosterone; Depression; Female; Humans; Male; Randomized Control | 2020 |
Dehydroepiandrosterone (DHEA) for Depression: A Systematic Review and Meta-Analysis.
Topics: Antidepressive Agents; Databases, Factual; Dehydroepiandrosterone; Depression; Humans | 2018 |
Neurobiology of DHEA and effects on sexuality, mood and cognition.
Topics: Affect; Animals; Anxiety; Brain; Cognition; Cognition Disorders; Dehydroepiandrosterone; Dehydroepia | 2015 |
The effects of dehydroepiandrosterone (DHEA) in the treatment of depression and depressive symptoms in other psychiatric and medical illnesses: a systematic review.
Topics: Adrenal Insufficiency; Anorexia Nervosa; Antidepressive Agents; Databases, Bibliographic; Dehydroepi | 2014 |
Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS).
Topics: Adult; Aged; Aging; Animals; Antioxidants; Brain; Dehydroepiandrosterone; Dehydroepiandrosterone Sul | 2009 |
A systematic review and meta-analysis of randomized placebo-controlled trials of DHEA treatment effects on quality of life in women with adrenal insufficiency.
Topics: Adrenal Insufficiency; Anxiety; Dehydroepiandrosterone; Depression; Health Status; Humans; Quality o | 2009 |
Dehydroepiandrosterone (DHEA)--a precursor steroid or an active hormone in human physiology.
Topics: Aging; Animals; Body Composition; Bone and Bones; Cardiovascular Diseases; Dehydroepiandrosterone; D | 2011 |
Androgen treatment of depressive symptoms in older men: a systematic review of feasibility and effectiveness.
Topics: Dehydroepiandrosterone; Depression; Feasibility Studies; Humans; Randomized Controlled Trials as Top | 2006 |
Drugs with estrogen-like potency and brain activity: potential therapeutic application for the CNS.
Topics: Alzheimer Disease; Animals; Brain; Dehydroepiandrosterone; Depression; Estrogens; Female; Humans; Ma | 2000 |
Sex hormones and their impact on dementia and depression: a clinical perspective.
Topics: Alzheimer Disease; Dehydroepiandrosterone; Depression; Estrogens; Gonadal Steroid Hormones; Humans; | 2001 |
8 trials available for dehydroepiandrosterone and Depression
| Article | Year |
|---|---|
Effects of Horticultural Therapy on Asian Older Adults: A Randomized Controlled Trial.
Topics: Aged; Anxiety; Asian People; Brain; Brain-Derived Neurotrophic Factor; Chemokine CXCL12; Cognition; | 2018 |
Effects of Horticultural Therapy on Asian Older Adults: A Randomized Controlled Trial.
Topics: Aged; Anxiety; Asian People; Brain; Brain-Derived Neurotrophic Factor; Chemokine CXCL12; Cognition; | 2018 |
Effects of Horticultural Therapy on Asian Older Adults: A Randomized Controlled Trial.
Topics: Aged; Anxiety; Asian People; Brain; Brain-Derived Neurotrophic Factor; Chemokine CXCL12; Cognition; | 2018 |
Effects of Horticultural Therapy on Asian Older Adults: A Randomized Controlled Trial.
Topics: Aged; Anxiety; Asian People; Brain; Brain-Derived Neurotrophic Factor; Chemokine CXCL12; Cognition; | 2018 |
Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial.
Topics: Adult; Aged; Dehydroepiandrosterone; Depression; Double-Blind Method; Fatigue; Female; Follow-Up Stu | 2010 |
Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial.
Topics: Adult; Aged; Dehydroepiandrosterone; Depression; Double-Blind Method; Fatigue; Female; Follow-Up Stu | 2010 |
Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial.
Topics: Adult; Aged; Dehydroepiandrosterone; Depression; Double-Blind Method; Fatigue; Female; Follow-Up Stu | 2010 |
Effects of dehydroepiandrosterone on fatigue and well-being in women with quiescent systemic lupus erythematosus: a randomised controlled trial.
Topics: Adult; Aged; Dehydroepiandrosterone; Depression; Double-Blind Method; Fatigue; Female; Follow-Up Stu | 2010 |
A history of depression in women is associated with an altered GABAergic neuroactive steroid profile.
Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Depression; Double-Blind Method; Female; Humans | 2012 |
Does simvastatin affect mood and steroid hormone levels in hypercholesterolemic men? A randomized double-blind trial.
Topics: Adult; Affect; Anticholesteremic Agents; Cross-Over Studies; Dehydroepiandrosterone; Depression; Die | 2003 |
The clinical course of interstitial pneumonia alias chronic fatigue syndrome under the control of megadose vitamin C infusion system with dehydroepiandrosterone-cortisol annex.
Topics: Adult; Aged; Ascorbic Acid; Dehydroepiandrosterone; Depression; Fatigue Syndrome, Chronic; Female; F | 2005 |
Long-term low-dose dehydroepiandrosterone replacement therapy in aging males with partial androgen deficiency.
Topics: Aged; Aging; Androgens; Andropause; Arthralgia; beta-Endorphin; Dehydroepiandrosterone; Dehydroepian | 2004 |
Dehydroepiandrosterone replacement in women with adrenal insufficiency.
Topics: Adrenal Insufficiency; Adult; Affect; Androgens; Anxiety; Cross-Over Studies; Dehydroepiandrosterone | 1999 |
Dehydroepiandrosterone replacement in women with adrenal insufficiency.
Topics: Adrenal Insufficiency; Adult; Affect; Androgens; Anxiety; Cross-Over Studies; Dehydroepiandrosterone | 1999 |
Dehydroepiandrosterone replacement in women with adrenal insufficiency.
Topics: Adrenal Insufficiency; Adult; Affect; Androgens; Anxiety; Cross-Over Studies; Dehydroepiandrosterone | 1999 |
Dehydroepiandrosterone replacement in women with adrenal insufficiency.
Topics: Adrenal Insufficiency; Adult; Affect; Androgens; Anxiety; Cross-Over Studies; Dehydroepiandrosterone | 1999 |
DHEA for depression?
Topics: Affect; Body Composition; Dehydroepiandrosterone; Depression; Female; HIV Infections; Humans; Male; | 2001 |
68 other studies available for dehydroepiandrosterone and Depression
| Article | Year |
|---|---|
Do neurosteroids have impact on depression and cognitive functions in cases with acromegaly?
Topics: Acromegaly; Animals; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; | 2022 |
Morning salivary dehydroepiandrosterone (DHEA) qualifies as the only neuroendocrine biomarker separating depressed patients with and without prior history of depression: An HPA axis challenge study.
Topics: Adrenocorticotropic Hormone; Biomarkers; Dehydroepiandrosterone; Depression; Depressive Disorder, Ma | 2023 |
Associations of DHEA(S) with negative and positive affect in people who smoke daily with elevated and low depression symptoms: A pilot laboratory study.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; Humans; Smoking; Smoking Cessati | 2023 |
Early trauma moderates the link between familial risk for depression and post-stress DHEA/cortisol ratios in adolescents.
Topics: Adolescent; Child; Dehydroepiandrosterone; Depression; Family; Female; Humans; Hydrocortisone; Hypot | 2019 |
Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy.
Topics: Adult; Dehydroepiandrosterone; Depression; HIV Infections; Humans; Hydrocortisone; Hypothalamo-Hypop | 2021 |
Hormonal Function Responses to Moderate Aerobic Exercise in Older Adults with Depression.
Topics: Aged; Aged, 80 and over; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; Exercis | 2020 |
Testosterone, estradiol, DHEA and cortisol in relation to anxiety and depression scores in adolescents.
Topics: Adolescent; Anxiety; Cross-Sectional Studies; Dehydroepiandrosterone; Depression; Estradiol; Female; | 2021 |
Profiling coping strategies in male and female rats: Potential neurobehavioral markers of increased resilience to depressive symptoms.
Topics: Adaptation, Psychological; Animals; Behavior, Animal; Biomarkers; Brain; Corticosterone; Dehydroepia | 2017 |
Neurosteroid dehydroepiandrosterone improves active avoidance retrieval and induces antidepressant-like behavior in rats.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Dehydroepiandrosterone; Depres | 2017 |
Associations of Peritoneal Glucose Load With Male Sexual Dysfunction and Depression in Peritoneal Dialysis Patients.
Topics: Aged; Cross-Sectional Studies; Dehydroepiandrosterone; Depression; Erectile Dysfunction; Estradiol; | 2018 |
The association between pubertal status and depressive symptoms and diagnoses in adolescent females: A population-based cohort study.
Topics: Adolescent; Breast; Child; Dehydroepiandrosterone; Depression; Female; Humans; Interview, Psychologi | 2018 |
The effect of nonsurgical periodontal treatment on gingival crevicular fluid stress hormone levels: A prospective study.
Topics: Adult; Anxiety; Case-Control Studies; Chronic Periodontitis; Dehydroepiandrosterone; Dental Plaque I | 2019 |
Relationships between adrenarcheal hormones, hippocampal volumes and depressive symptoms in children.
Topics: Adrenal Glands; Adrenarche; Androgens; Brain; Child; Cross-Sectional Studies; Dehydroepiandrosterone | 2019 |
Do dehydroepiandrosterone, progesterone, and testosterone influence women's depression and anxiety levels? Evidence from hair-based hormonal measures of 2105 rural Indian women.
Topics: Adult; Aged; Aged, 80 and over; Androgens; Anxiety; Anxiety Disorders; Cohort Studies; Dehydroepiand | 2019 |
Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice.
Topics: Animals; Behavior, Animal; beta Catenin; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dehydro | 2013 |
Depressive symptoms in hip fracture patients are associated with reduced monocyte superoxide production.
Topics: Aged; Aged, 80 and over; Analysis of Variance; B7-1 Antigen; B7-2 Antigen; Case-Control Studies; Cyt | 2014 |
Association of gingival crevicular fluid cortisol/dehydroepiandrosterone levels with periodontal status.
Topics: Adult; Anxiety; Chronic Periodontitis; Cross-Sectional Studies; Dehydroepiandrosterone; Dental Plaqu | 2014 |
Altered one-carbon metabolism in posttraumatic stress disorder.
Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Depression; Female; Folic Acid; Homocysteine; H | 2015 |
Hormonal determinants of the severity of andropausal and depressive symptoms in middle-aged and elderly men with prediabetes.
Topics: Aged; Aged, 80 and over; Aging; Andropause; Dehydroepiandrosterone; Depression; Humans; Insulin-Like | 2015 |
Depression, immune function, and early adrenarche in children.
Topics: Adrenarche; C-Reactive Protein; Child; Child Behavior; Cohort Studies; Dehydroepiandrosterone; Depre | 2016 |
Comparative Analysis of Psychological, Hormonal, and Genetic Factors Between Burning Mouth Syndrome and Secondary Oral Burning.
Topics: Adult; Aged; Burning Mouth Syndrome; Cross-Sectional Studies; Dehydroepiandrosterone; Depression; Fe | 2016 |
Association of pain intensity, pain-related disability, and depression with hypothalamus-pituitary-adrenal axis function in female patients with chronic temporomandibular disorders.
Topics: Adult; Chronic Pain; Circadian Rhythm; Comorbidity; Dehydroepiandrosterone; Depression; Depressive D | 2016 |
Sex differences in the serum level of endogenous ligands for estrogen receptor β in the elderly population.
Topics: Aged; Chromatography, Liquid; Dehydroepiandrosterone; Depression; Estradiol; Estrogen Receptor beta; | 2016 |
Cortisol, DHEA, and depression in the elderly: the influence of physical capacity.
Topics: Aged; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Dehydroepiandrosterone; Depression; | 2016 |
Depression-Like Behavior in a Dehydroepiandrosterone-Induced Mouse Model of Polycystic Ovary Syndrome.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Brain; Dehydroepiandrosterone; Depression; Diet, Hig | 2016 |
The rate of change in declining steroid hormones: a new parameter of healthy aging in men?
Topics: Adult; Aged; Aging; Biomarkers; Dehydroepiandrosterone; Depression; Estradiol; Gonadal Steroid Hormo | 2016 |
The role of steroids in the prediction of affective disorders in adult men.
Topics: Adult; Anxiety; Dehydroepiandrosterone; Depression; Female; Gas Chromatography-Mass Spectrometry; Hu | 2017 |
A comparison of quality of life, demographic and clinical characteristics of Brazilian men with fibromyalgia syndrome with male patients with depression.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Anxiety; Brazil; Dehydroepiandrosterone; Demogr | 2010 |
Salivary dehydroepiandrosterone (DHEA) levels in patients with the complaint of burning mouth: a case-control study.
Topics: Adult; Aged; Aged, 80 and over; Burning Mouth Syndrome; Case-Control Studies; Circadian Rhythm; Dehy | 2009 |
Depression-like behavior and reduced plasma testosterone levels in the senescence-accelerated mouse.
Topics: Acoustic Stimulation; Aging; Analysis of Variance; Animals; Behavior, Animal; Dehydroepiandrosterone | 2010 |
Deficiencies in circulating testosterone and dehydroepiandrosterone sulphate, and depression in men with systolic chronic heart failure.
Topics: Adult; Biomarkers; Dehydroepiandrosterone; Depression; Disease Progression; Follow-Up Studies; Heart | 2010 |
Salivary cortisol and dehydroepiandrosterone (DHEA) levels, psychological factors in patients with oral lichen planus.
Topics: Adult; Anxiety; Case-Control Studies; Dehydroepiandrosterone; Depression; Female; Humans; Hydrocorti | 2011 |
Behavioral training and predisposed coping strategies interact to influence resilience in male Long-Evans rats: implications for depression.
Topics: Adaptation, Psychological; Animals; Anxiety; Behavior, Animal; Brain; Brain Chemistry; Corticosteron | 2012 |
Association of sex hormones and sex hormone-binding globulin with depressive symptoms in postmenopausal women: the Multiethnic Study of Atherosclerosis.
Topics: Aged; Aged, 80 and over; Asian; Atherosclerosis; Black People; Dehydroepiandrosterone; Depression; E | 2012 |
Salivary cortisol and dehydroepiandrosterone sulfate in adolescent rape victims with post traumatic stress disorder.
Topics: Adolescent; Adolescent Behavior; Case-Control Studies; Crime Victims; Dehydroepiandrosterone; Depres | 2013 |
Basal plasma hormone levels in depressed perimenopausal women.
Topics: Adult; Climacteric; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; Estradiol; E | 2002 |
Adolescent depression, cortisol and DHEA.
Topics: Adolescent; Adolescent Psychiatry; Circadian Rhythm; Dehydroepiandrosterone; Depression; Humans; Hyd | 2003 |
Progesterone increase under DHEA-substitution in males.
Topics: Aged; Dehydroepiandrosterone; Depression; Fatigue; Humans; Male; Middle Aged; Progesterone; Testoste | 2003 |
Obesity enhances verbal memory in postmenopausal women with Down syndrome.
Topics: Adult; Body Mass Index; Case-Control Studies; Dehydroepiandrosterone; Depression; Down Syndrome; Est | 2004 |
Changes in cortisol and dehydroepiandrosterone in women victims of physical and psychological intimate partner violence.
Topics: Adult; Analysis of Variance; Anxiety; Battered Women; Crime Victims; Dehydroepiandrosterone; Depress | 2004 |
The involvement of dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS) in blocking the therapeutic effect of electroconvulsive shocks in an animal model of depression.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Brain Chemistry; Cytosol; Dehydroepiandrosterone; Dehyd | 2005 |
DHEA: over-the-counter antidote for depression. Non-prescription hormonal supplement can help relieve minor and major depression in middle age.
Topics: Antidepressive Agents; Dehydroepiandrosterone; Depression; Humans | 2005 |
Neuropsychopharmacological properties of neuroactive steroids in depression and anxiety disorders.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Dehydroepiandrosterone; Dehydroepiandrosterone | 2006 |
DHEA for depression.
Topics: Aged; Antidepressive Agents; Dehydroepiandrosterone; Depression; Humans; Middle Aged | 2005 |
Psychological well-being and ill-being: do they have distinct or mirrored biological correlates?
Topics: Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Dehydroepiandrosterone; Depression; Fe | 2006 |
A decrease in the plasma DHEA to cortisol ratio during smoking abstinence may predict relapse: a preliminary study.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; Female; Humans; Hydrocort | 2006 |
Basal cortisol and DHEA levels in women with borderline personality disorder.
Topics: Adaptation, Psychological; Adult; Borderline Personality Disorder; Child; Child Abuse; Dehydroepiand | 2007 |
The protective effect of frontal cortex dehydroepiandrosterone in anxiety and depressive models in mice.
Topics: Animals; Anxiety; Castration; Dehydroepiandrosterone; Depression; Disease Models, Animal; Estradiol; | 2006 |
DHEA and health: more questions than answers.
Topics: Aging; Cognition; Coronary Artery Disease; Dehydroepiandrosterone; Depression; Dietary Supplements; | 2007 |
Sex differences in the relationship between DHEAS and health.
Topics: Aged; Aging; Asian People; Biomarkers; Cognition Disorders; Dehydroepiandrosterone; Dehydroepiandros | 2007 |
DHEA lessens depressive-like behavior via GABA-ergic modulation of the mesolimbic system.
Topics: Animals; Antidepressive Agents; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; | 2009 |
Serum androgens and psychopathology in hirsute women.
Topics: Acne Vulgaris; Adolescent; Adult; Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; | 1993 |
Antidepressant and cognition-enhancing effects of DHEA in major depression.
Topics: Affect; Aged; Aging; Cognition; Dehydroepiandrosterone; Depression; Female; Humans; Male; Middle Age | 1995 |
Steroid hormones, the menopause, sexuality and well-being of women.
Topics: Adult; Affect; Analysis of Variance; Chi-Square Distribution; Climacteric; Dehydroepiandrosterone; D | 1996 |
Androgens in the elderly: will androgen replacement therapy improve mood, cognition, and quality of life in aging men and women.
Topics: Affect; Aged; Alzheimer Disease; Androgens; Cognition; Dehydroepiandrosterone; Depression; Female; G | 1997 |
Determinants of functional status in healthy Italian nonagenarians and centenarians: a comprehensive functional assessment by the instruments of geriatric practice.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Anthropometry; Dehydroepiandrosterone; Depressi | 1997 |
Dehydroepiandrosterone decreases behavioral despair in high- but not low-anxiety rats.
Topics: Animals; Anxiety; Arousal; Corticosterone; Dehydroepiandrosterone; Depression; Fear; Helplessness, L | 1997 |
Increased diurnal plasma concentrations of dehydroepiandrosterone in depressed patients.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Body Mass Index; Circadian Rhythm; Dehydroepiandros | 1998 |
Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations.
Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Depression; Ethanol; Female; Homovanillic Acid; | 1999 |
DHEA for depression.
Topics: Clinical Trials as Topic; Dehydroepiandrosterone; Depression; Female; HIV Infections; Humans; Male; | 1997 |
DHEA. Is it useful for treating depression?
Topics: Clinical Trials as Topic; Dehydroepiandrosterone; Depression; Female; HIV Infections; Humans; Male | 2001 |
DHEA--cautions and concerns.
Topics: Contraindications; Dehydroepiandrosterone; Depression; HIV Infections; Humans; Neoplasms, Hormone-De | 2001 |
Inflammatory and hormonal measures predict neuropsychological functioning in systemic lupus erythematosus and rheumatoid arthritis patients.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Attention; Case-Control Studies; Cognition; | 2001 |
Cortisol/DHEA ratios in depression.
Topics: Dehydroepiandrosterone; Depression; Female; Humans; Hydrocortisone | 2002 |
Effect of prolactin on plasma DHEA (s) levels.
Topics: Adult; Aged; Antidepressive Agents; Dehydroepiandrosterone; Dementia; Depression; Estrogens; Female; | 1977 |
Serum androgens and depression in women with facial hirsutism.
Topics: Adolescent; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Depression; Face; Female; Hir | 1992 |
Urinary 17-ketosteroid fractionation in depression: a preliminary report.
Topics: 17-Ketosteroids; Adult; Androgens; Dehydroepiandrosterone; Depression; Humans; Hydrocortisone; Male; | 1969 |
Urinary steroids in depressive illness.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androsterone; Antidepressive Agents; Chroma | 1971 |