Page last updated: 2024-11-13

bacopaside i

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

bacopaside I: isolated from Bacopa monniera Wettst; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
BacopagenusA plant genus of the family Plantaginaceae. Members contain bacopaside, bacopasaponins and other dammarane type jujubogenins.[MeSH]PlantaginaceaeA plant family of order Lamiales. The Plantago genus is best known. Lesser known members include Hippuris, Littorella and Callitriche.[MeSH]

Cross-References

ID SourceID
PubMed CID21599442
MeSH IDM0408600

Synonyms (14)

Synonym
bacopaside i
3-o-alpha-l-arabinofuranosyl-(1-2)-(6-o-sulphonyl-beta-d-glucopyranosyl-(1-3))-alpha-l-arabinopyranosyl pseudo-jujubogenin
382148-47-2
unii-36b8wua361
36B8WUA361 ,
bacopaside i, (-)-
bacopaside i (constituent of bacopa) [dsc]
[(2r,3s,4s,5r,6s)-6-[(2s,3r,4s,5s)-3-[(2s,3r,4r,5s)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-5-hydroxy-2-[[(1s,2r,5r,7s,10r,11r,14r,15s,16s,17r,20r)-16-hydroxy-2,6,6,10,16-pentamethyl-17-(2-methylprop-1-enyl)-19,21-dioxahexacyclo[18.2.1.01,14.02,11.
bacopaside i(sh)
HY-N4246
CS-0032525
Q27256548
AS-82791
AKOS040760286

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" This method was successfully applied to the preclinical pharmacokinetic study of bacopaside I following intravenous or oral administration to rats."( A simple LC-ESI-MS/MS method for quantification of bacopaside I in rat plasma and its application to a pharmacokinetic study.
Song, ZM; Wen, SM; Xiong, K; Xu, F; Yin, RF, 2016
)
0.91

Bioavailability

ExcerptReferenceRelevance
" Bioavailability as well as binding of neuroprotective agents (such as bacosides) to these receptors is controlled by the Blood Brain Barrier (BBB)."( Insights Into the Molecular Aspects of Neuroprotective Bacoside A and Bacopaside I.
Baby, S; Sekhar, VC; Viswanathan, G, 2019
)
0.75
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (21)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (19.05)29.6817
2010's15 (71.43)24.3611
2020's2 (9.52)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.21

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.21 (24.57)
Research Supply Index3.18 (2.92)
Research Growth Index5.09 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (21.21)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews3 (13.04%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other20 (86.96%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]