mifepristone has been researched along with Depression in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 20 (64.52) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Aoki, Y; Aritomo, K; Eda, M; Ikeda, Y; Kaneko, S; Koyama, N; Kuroda, T; Ohbora, T; Okumura, C; Sakaue, M; Yamashita, M | 1 |
| da Silva Junior, ED; Gavioli, EC; Holanda, VAD; Oliveira, MC | 1 |
| Nayana, J; Shankaranarayana Rao, BS; Srikumar, BN | 1 |
| Coleman, R; Coulton, S; Donoghue, K; Drummond, C; Little, H; Milward, J; Philips, T; Rose, A | 1 |
| Belanoff, J; Block, TS; Kalin, N; Kushner, H; Nelson, C; Schatzberg, A | 1 |
| Golier, JA; Yehuda, R | 1 |
| Chen, NH; Li, J; Lou, YX; Wang, ZZ; Xia, CY | 1 |
| Jiang, H; Liu, D; Liu, Y; Pan, F; Wang, R; Wang, W; Xu, J | 1 |
| Horchar, MJ; Wohleb, ES | 1 |
| Benton, TD; Blume, J; Douglas, SD; Dubé, B; Evans, DL; Gettes, DR; Lynch, KG; Metzger, DS; Tustin, NB | 1 |
| Anacker, C; Calabrese, F; Cattaneo, A; Gennarelli, M; Horowitz, M; Luoni, A; Molteni, R; Musaelyan, K; Pariante, CM; Price, J; Riva, MA; Tansey, K; Thuret, S; Uher, R; Zunszain, PA | 1 |
| Chen, NH; Li, J; Liu, Y; Sun, JD; Yuan, YH | 1 |
| Hu, P; Liu, J; Lucassen, PJ; Qi, CC; Qi, XR; Zhao, J; Zhou, JN | 1 |
| Howland, RH | 1 |
| Chijiwa, T; Lkhagvasuren, B; Oka, T; Sudo, N; Yoshihara, K | 1 |
| Schatzberg, AF | 1 |
| Caramanica, K; Golier, JA; Harvey, PD; Makotkine, I; Michaelides, AC; Schmeidler, J; Yehuda, R | 1 |
| Ficek, J; Golda, S; Korostynski, M; Piechota, M; Przewlocki, R; Szklarczyk, K | 1 |
| Bhuiyan, MS; Fukunaga, K; Han, F; Hasegawa, H; Kanai, H; Shinoda, Y; Tagashira, H; Zhang, C | 1 |
| Belanoff, JK; Blasey, CM; Block, T; Debattista, C; Roe, R | 1 |
| Herman, JP; Solomon, MB; Wulsin, AC | 1 |
| Beckley, EH; Finn, DA; Scibelli, AC | 1 |
| Kuang, X; Lin, W; Pan, Y; Qi, X; Sun, H; Wang, D | 1 |
| Gao, Y; Li, Z; Liu, H; Wu, Y; Xu, Z; Zhang, C; Zhang, S | 1 |
| Spitz, IM | 1 |
| Hu, F; Miller, AH; Pace, TW; Wang, X; Wu, H | 1 |
| Creinin, MD; Hanusa, BH; Rothschild, AJ; Sit, D; Wisner, KL | 1 |
| Aisa, B; Del Río, J; Lasheras, B; Ramírez, MJ; Tordera, R | 1 |
| Han, H; Hou, HL; Tong, H; Wang, QN; Wu, LM; Yan, XB; Zhou, JN | 1 |
| Templeton, AA; Urquhart, DR | 1 |
3 review(s) available for mifepristone and Depression
| Article | Year |
|---|---|
Mifepristone's effects on depression- and anxiety-like behavior in rodents.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Depression; Glucocorticoids; Mifepristone; Progesterone; Receptors, Glucocorticoid; Rodentia | 2022 |
Development of New Psychopharmacological Agents for Depression and Anxiety.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Botulinum Toxins; Depression; Excitatory Amino Acid Antagonists; Hormone Antagonists; Humans; Ketamine; Mifepristone; Molecular Targeted Therapy; Synaptic Transmission | 2015 |
Progesterone antagonists and progesterone receptor modulators: an overview.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Depression; Dimerization; Female; Glucocorticoids; Hormone Antagonists; Humans; Logistic Models; Mifepristone; Models, Biological; Myoma; Pregnancy; Progesterone; Receptors, Progesterone | 2003 |
5 trial(s) available for mifepristone and Depression
| Article | Year |
|---|---|
Double-blind, placebo-controlled trial of mifepristone on cognition and depression in alcohol dependence.
Topics: Alcoholism; Cognition; Depression; Double-Blind Method; Humans; Male; Mifepristone; Treatment Outcome | 2020 |
Combined Analysis of Mifepristone for Psychotic Depression: Plasma Levels Associated With Clinical Response.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Mifepristone; Time Factors; Treatment Outcome; Young Adult | 2018 |
Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis.
Topics: Active Transport, Cell Nucleus; Adult; Animals; Benzoates; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Cell Nucleus; Depression; Female; Glucocorticoids; Hedgehog Proteins; Hippocampus; Humans; Hydrocortisone; Immediate-Early Proteins; Male; Middle Aged; Mifepristone; Nerve Tissue Proteins; Neurogenesis; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Messenger; Signal Transduction; Stress, Physiological | 2013 |
A randomized, double-blind, placebo-controlled, crossover trial of mifepristone in Gulf War veterans with chronic multisymptom illness.
Topics: Adult; Chronic Disease; Cognition; Cross-Over Studies; Depression; Dexamethasone; Double-Blind Method; Fatigue; Female; Gulf War; Health Status; Humans; Hydrocortisone; Male; Middle Aged; Mifepristone; Pituitary-Adrenal Function Tests; Receptors, Glucocorticoid; Stress Disorders, Post-Traumatic; Veterans | 2016 |
A multisite trial of mifepristone for the treatment of psychotic depression: a site-by-treatment interaction.
Topics: Adult; Antidepressive Agents; Brief Psychiatric Rating Scale; Comorbidity; Depression; Drug Administration Routes; Humans; Mifepristone; Psychotic Disorders; Receptors, Glucocorticoid | 2009 |
23 other study(ies) available for mifepristone and Depression
| Article | Year |
|---|---|
Synthesis and Biological Evaluation of Cyclopentaquinoline Derivatives as Nonsteroidal Glucocorticoid Receptor Antagonists.
Topics: Animals; Antidepressive Agents; Cell Line; Depression; Humans; Male; Molecular Docking Simulation; Quinolines; Rats; Rats, Wistar; Receptors, Glucocorticoid; Structure-Activity Relationship | 2015 |
Tamsulosin facilitates depressive-like behaviors in mice: Involvement of endogenous glucocorticoids.
Topics: Adaptation, Psychological; Adrenergic alpha-1 Receptor Antagonists; Aminoglutethimide; Animals; Aromatase Inhibitors; Behavior, Animal; Depression; Disease Models, Animal; Hormone Antagonists; Hypothalamo-Hypophyseal System; Mice; Mifepristone; Receptors, Glucocorticoid; Tamsulosin | 2022 |
Mifepristone as a Psychopharmacologic Agent: Consideration of Efficacy, Plasma Levels, and Mechanism of Action.
Topics: Bipolar Disorder; Depression; Depressive Disorder, Major; Humans; Mifepristone; Psychotic Disorders | 2018 |
Glucocorticoid receptor activation induces decrease of hippocampal astrocyte number in rats.
Topics: Animals; Astrocytes; Cell Count; Corticosterone; Depression; Glucocorticoids; Hippocampus; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Psychological | 2018 |
Short- and long-term alterations of FKBP5-GR and specific microRNAs in the prefrontal cortex and hippocampus of male rats induced by adolescent stress contribute to depression susceptibility.
Topics: Age Factors; Animals; Brain; Depression; Depressive Disorder; Disease Susceptibility; Glucocorticoids; Hippocampus; Hypothalamo-Hypophyseal System; Male; MicroRNAs; Mifepristone; Pituitary-Adrenal System; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress, Psychological; Tacrolimus Binding Proteins | 2019 |
Glucocorticoid receptor antagonism prevents microglia-mediated neuronal remodeling and behavioral despair following chronic unpredictable stress.
Topics: Animals; Behavior, Animal; Brain; Corticosterone; Depression; Hippocampus; Macrophage Colony-Stimulating Factor; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Mifepristone; Neuronal Plasticity; Neurons; Prefrontal Cortex; Pyramidal Cells; Receptors, Glucocorticoid; Stress, Psychological | 2019 |
The glucocorticoid antagonist RU-486 suppresses HIV infectivity and replication.
Topics: Adolescent; Adult; Cell Line; Depression; Female; HIV Infections; Hormone Antagonists; Humans; Middle Aged; Mifepristone; Psychiatric Status Rating Scales; Retrospective Studies; T-Lymphocytes; Viral Load; Virus Replication; Young Adult | 2013 |
[Mifepristone repairs alteration of learning and memory abilities in rat model of depression].
Topics: Animals; Behavior, Animal; Corticosterone; Depression; Hippocampus; Learning; Male; Memory; Mifepristone; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Psychological | 2013 |
All-trans retinoic acid-induced hypothalamus-pituitary-adrenal hyperactivity involves glucocorticoid receptor dysregulation.
Topics: Animals; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Depression; Dexamethasone; Feedback, Physiological; Glucocorticoids; Hormone Antagonists; Hydrocortisone; Hypothalamo-Hypophyseal System; Mifepristone; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Rats; Receptors, Glucocorticoid; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Signal Transduction; Tretinoin | 2013 |
Odds and ends in psychopharmacology from the past 10 years.
Topics: Acetamides; Anti-Obesity Agents; Antidepressive Agents; Central Nervous System Stimulants; Depression; Electroencephalography; History, 21st Century; Humans; Mifepristone; Obesity; Psychopharmacology; Stereoisomerism | 2015 |
Prior chronic stress induces persistent polyI:C-induced allodynia and depressive-like behavior in rats: Possible involvement of glucocorticoids and microglia.
Topics: Animals; Body Weight; Depression; Disease Models, Animal; Drug Administration Routes; Eating; Fever; Hormone Antagonists; Hyperalgesia; Interferon Inducers; Male; Mifepristone; Minocycline; Pain Management; Poly I-C; Rats; Rats, Long-Evans; Rats, Wistar; Stress, Psychological; Swimming; Time Factors | 2015 |
Endogenous opioids regulate glucocorticoid-dependent stress-coping strategies in mice.
Topics: Adaptation, Psychological; Amygdala; Animals; Anxiety; Conditioning, Psychological; Depression; Dexamethasone; Fear; Freezing Reaction, Cataleptic; Glucocorticoids; Male; Mice, Inbred Strains; Mifepristone; Motor Activity; Naltrexone; Neurotransmitter Agents; Opioid Peptides; Receptors, Glucocorticoid; Receptors, Opioid; Species Specificity; Stress, Psychological | 2016 |
Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression.
Topics: Adenosine Triphosphate; Administration, Oral; Animals; Aorta; Behavior, Animal; Cardiomegaly; Corticosterone; Dentate Gyrus; Depression; Disease Models, Animal; Down-Regulation; Echocardiography; Heart Failure; Hippocampus; Male; Mice; Mice, Inbred ICR; Mifepristone; Piperazines; Receptors, sigma | 2016 |
Mifepristone decreases depression-like behavior and modulates neuroendocrine and central hypothalamic-pituitary-adrenocortical axis responsiveness to stress.
Topics: Adrenocorticotropic Hormone; Amygdala; Animals; Corticosterone; Depression; Hippocampus; Hypothalamo-Hypophyseal System; Hypothalamus; Limbic System; Male; Mifepristone; Pituitary-Adrenal System; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Receptors, Glucocorticoid; Stress, Psychological; Swimming | 2010 |
Progesterone receptor antagonist CDB-4124 increases depression-like behavior in mice without affecting locomotor ability.
Topics: Animals; Depression; Depression, Postpartum; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Finasteride; Locomotion; Mice; Mice, Inbred DBA; Mifepristone; Norpregnadienes; Premenstrual Syndrome; Progesterone; Receptors, Progesterone; Single-Blind Method; Swimming | 2011 |
Chronic blockade of glucocorticoid receptors by RU486 enhances lipopolysaccharide-induced depressive-like behaviour and cytokine production in rats.
Topics: Analysis of Variance; Animals; Cytokines; Depression; Hormone Antagonists; Illness Behavior; Interferon-gamma; Interleukin-1beta; Lipopolysaccharides; Male; Mifepristone; Motor Activity; Rats; Rats, Wistar; Receptors, Glucocorticoid; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
Bidirectional crosstalk between stress-induced gastric ulcer and depression under chronic stress.
Topics: Animals; Anti-Ulcer Agents; Corticosterone; Depression; Fluoxetine; Male; Mifepristone; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Stress, Psychological | 2012 |
New treatments for depression with psychosis. Two experimental treatments for depression have shown promise in preliminary studies; one a relatively new drug, the other a familiar hormone.
Topics: Antipsychotic Agents; Depression; Humans; Male; Mifepristone; Psychotic Disorders; Testosterone | 2003 |
Inhibition of COX-2 by celecoxib enhances glucocorticoid receptor function.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Depression; Dose-Response Relationship, Drug; Drug Interactions; Hormone Antagonists; Mifepristone; Neurons; PC12 Cells; Pyrazoles; Rats; Receptors, Glucocorticoid; Sulfonamides | 2005 |
Psychiatric outcomes following medical and surgical abortion.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Adolescent; Adult; Antidepressive Agents; Depression; Female; Humans; Hydrocortisone; Mifepristone; Mood Disorders; Pregnancy; Saliva; Vacuum Curettage | 2007 |
Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats.
Topics: Adaptation, Psychological; Analysis of Variance; Animals; Cognition Disorders; Corticosterone; Corticotropin-Releasing Hormone; Critical Period, Psychological; Depression; Exploratory Behavior; Female; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Maternal Deprivation; Mifepristone; Motor Activity; Norepinephrine; Paraventricular Hypothalamic Nucleus; Random Allocation; Rats; Rats, Wistar; Receptors, Glucocorticoid; Recognition, Psychology; RNA, Messenger; Sex Factors; Statistics, Nonparametric | 2007 |
Mifepristone repairs region-dependent alteration of synapsin I in hippocampus in rat model of depression.
Topics: Analysis of Variance; Animals; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Food Preferences; Hippocampus; Hormone Antagonists; Male; Mifepristone; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Statistics as Topic; Synapsins | 2007 |
Psychiatric morbidity and acceptability following medical and surgical methods of induced abortion.
Topics: Abortion, Therapeutic; Anxiety; Depression; Female; Humans; Mifepristone; Patient Acceptance of Health Care; Pregnancy; Prostaglandins; Psychological Tests; Time Factors; Vacuum Curettage | 1991 |