Page last updated: 2024-08-21

alpha-aminopyridine and Depression

alpha-aminopyridine has been researched along with Depression in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Cai, Z; Chen, Z; Huang, C; Lu, J; Lu, X; Tong, L; Wang, D; Ye, T; Yuan, X1
Chen, W; Fu, HR; Gao, YF; Wang, H; Wang, L; Wang, XD; Xu, XY; Xu, Y; Zhang, FF; Zhang, HT; Zhang, JG1
Goralski, JL; McKinzie, CJ; Noah, TL; Prieur, MB; Retsch-Bogart, GZ1
Bilello, JA; Dickerson, BC; English, BA; Ereshefsky, L; Fava, M; Flynn, M; Freeman, MP; Gertsik, LG; Hoeppner, BB; Johe, K; Johnstone, J; Kinrys, G; Makris, N; Mischoulon, D; Thurmond, LM1
Costes, N; Didelot, A; Gilliam, F; Hammers, A; Lothe, A; Ryvlin, P; Saoud, M1
Assié, MB; Auclair, AL; Bardin, L; Carilla-Durand, E; Colpaert, F; Depoortère, R; Kleven, MS; Koek, W; Newman-Tancredi, A; Vacher, B1
Long, BC; Miller, BH; Pletcher, MT; Schultz, LE1
Ballanger, B; Broussolle, E; Eche, J; Klinger, H; Le Bars, D; Lerond, J; Sgambato-Faure, V; Thobois, S; Tremblay, L; Vallet, AE1
Harrison, AA; Liem, YT; Markou, A1

Trials

1 trial(s) available for alpha-aminopyridine and Depression

ArticleYear
A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients.
    Molecular psychiatry, 2016, Volume: 21, Issue:10

    Topics: Adult; Aminopyridines; Biomarkers, Pharmacological; Depression; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2016

Other Studies

8 other study(ies) available for alpha-aminopyridine and Depression

ArticleYear
Antidepressive properties of macrophage-colony stimulating factor in a mouse model of depression induced by chronic unpredictable stress.
    Neuropharmacology, 2020, 08-01, Volume: 172

    Topics: Aminopyridines; Animals; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Hippocampus; Macrophage Activation; Macrophage Colony-Stimulating Factor; Male; Mice; Mice, Inbred C57BL; Microglia; Minocycline; Pyrroles; Stress, Psychological

2020
The Phosphodiesterase-4 Inhibitor Roflumilast, a Potential Treatment for the Comorbidity of Memory Loss and Depression in Alzheimer's Disease: A Preclinical Study in APP/PS1 Transgenic Mice.
    The international journal of neuropsychopharmacology, 2020, 12-10, Volume: 23, Issue:10

    Topics: Alzheimer Disease; Aminopyridines; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Benzamides; Cerebral Cortex; Cyclopropanes; Depression; Disease Models, Animal; Hippocampus; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphodiesterase 4 Inhibitors; Presenilin-1; Recognition, Psychology

2020
Worsening anxiety and depression after initiation of lumacaftor/ivacaftor combination therapy in adolescent females with cystic fibrosis.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2017, Volume: 16, Issue:4

    Topics: Adolescent; Aminophenols; Aminopyridines; Antidepressive Agents; Anxiety; Benzodioxoles; Child; Cognitive Behavioral Therapy; Cystic Fibrosis; Depression; Drug Combinations; Female; Humans; Membrane Transport Modulators; Quinolones; Suicidal Ideation; Suicide, Attempted; Withholding Treatment

2017
Comorbidity between temporal lobe epilepsy and depression: a [18F]MPPF PET study.
    Brain : a journal of neurology, 2008, Volume: 131, Issue:Pt 10

    Topics: Adult; Aminopyridines; Brain; Cerebral Cortex; Depression; Epilepsy, Temporal Lobe; Female; Fluorodeoxyglucose F18; Hippocampus; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Piperazines; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Antagonists

2008
F15599, a highly selective post-synaptic 5-HT(1A) receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity.
    The international journal of neuropsychopharmacology, 2010, Volume: 13, Issue:10

    Topics: Aminopyridines; Animals; Antidepressive Agents; Corticosterone; Depression; Hypothermia; Male; Models, Animal; Molecular Targeted Therapy; Motor Activity; Piperidines; Prefrontal Cortex; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serotonin; Serotonin 5-HT1 Receptor Agonists; Stress, Physiological; Swimming

2010
Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice.
    Mammalian genome : official journal of the International Mammalian Genome Society, 2010, Volume: 21, Issue:5-6

    Topics: Aminopyridines; Animals; Behavior, Animal; Crosses, Genetic; Depression; Genotype; Hindlimb Suspension; Mice; Mice, Inbred C57BL; Mice, Inbred NZB; Quantitative Trait Loci; Receptors, GABA-A; Thiophenes

2010
Role of serotonergic 1A receptor dysfunction in depression associated with Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2012, Volume: 27, Issue:1

    Topics: Adult; Aged; Aminopyridines; Brain; Depression; Female; Fluorine Radioisotopes; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Piperazines; Positron-Emission Tomography; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists

2012
Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:1

    Topics: Aminopyridines; Amphetamine; Amphetamine-Related Disorders; Animals; Body Weight; Brain; Depression; Disease Models, Animal; Drug Combinations; Electric Stimulation; Fluoxetine; Male; Mecamylamine; Neurons; Nicotine; Nicotinic Antagonists; Piperazines; Rats; Rats, Wistar; Reaction Time; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Substance Withdrawal Syndrome; Synaptic Transmission; Tobacco Use Disorder

2001