aspartic acid has been researched along with Depression in 45 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, there were no associations between NAA/Cr, Glu/Cr, or Gln/Cr and either depression severity or lamotrigine treatment." | 7.91 | Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. ( Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M, 2019) |
| " The levels of total choline (tCho) and the tCho/N-acetyl aspartate (NAA) ratio were consistently higher in the brains of patients with depression, and that the levels of NAA, glutamate and glutamine (Glx), and gamma-aminobutyric acid (GABA) were lower." | 4.31 | Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies. ( Hu, L; Liu, Y; Lv, F; Ma, L; Pu, J; Shen, Y; Shi, Y; Xie, X; Yang, W; Zhang, H, 2023) |
| " MDD patients had significantly higher serum levels of glutamic acid, aspartic acid and glycine but lower levels of 3-Hydroxykynurenine; glutamic acid and phenylalanine levels also correlated with depression severity." | 4.31 | The Utility of Amino Acid Metabolites in the Diagnosis of Major Depressive Disorder and Correlations with Depression Severity. ( Ching, J; Ho, CSH; Tay, GWN; Wee, HN, 2023) |
| " In the same brain region, glutamate+glutamine is lower in methamphetamine users than in controls and is negatively correlated with depression." | 3.91 | N-Acetyl and Glutamatergic Neurometabolites in Perisylvian Brain Regions of Methamphetamine Users. ( Alger, JR; Johnson, MC; London, ED; O'Neill, J; Shen, Z; Tang, J, 2019) |
| " However, there were no associations between NAA/Cr, Glu/Cr, or Gln/Cr and either depression severity or lamotrigine treatment." | 3.91 | Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. ( Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M, 2019) |
| " Concentrations of glutamate + glutamin (Glx), cholin (Cho), myoinositol (mIns), N-acetyl aspartate (NAA) expressed as ratio with creatine (Cr) and NAA were correlated with markers of disease activity (RIO score), Multiple Sclerosis Severity Scale (MSSS), Depressive-Severity Status Scale and Simple Numerical Fatigue Scale." | 3.85 | Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue. ( Baranovičová, E; Bittšanský, M; Čierny, D; Hnilicová, P; Kantorová, E; Kurča, E; Nosáľ, V; Poláček, H; Sivák, Š; Zeleňák, K, 2017) |
| "One of the most striking discoveries in the treatment of major depression was the finding that infusion of a single sub-anesthetic dose of ketamine induces rapid and sustained antidepressant effects in treatment-resistant depressed patients." | 3.83 | Repeated ketamine treatment induces sex-specific behavioral and neurochemical effects in mice. ( Mauch, J; Pandit, R; Pitychoutis, PM; Sens, J; Thelen, C, 2016) |
| "The purpose of this study is to explore depression metabolic markers in rat hippocampus and to investigate the anti-depressant effect of genipin and its mechanisms using nuclear magnetic resonance (NMR) metabonomics." | 3.80 | [1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus]. ( Gao, S; Peng, GJ; Qin, XM; Shi, BY; Tian, JS, 2014) |
| "To identify possible alterations in orbitofrontal cortex levels of cytosolic choline in adolescents with and without depression, 22 depressed and 43 control adolescents were recruited." | 3.70 | Increased orbitofrontal cortex levels of choline in depressed adolescents as detected by in vivo proton magnetic resonance spectroscopy. ( Beardslee, WR; Hennen, J; Katic, A; Moore, CM; Moore, JC; Renshaw, PF; Steingard, RJ; Vakili, K; Young, AD; Yurgelun-Todd, DA, 2000) |
| "(1) Methadone was associated with normalisation of dorsal ACC biochemistry (increased N-acetylaspartate and glutamate/glutamine levels, and decreased myo-inositol levels) in a dose-dependent manner; (2) buprenorphine-treated individuals had higher myo-inositol and glutamate/glutamine levels than methadone-treated patients in the right dorsal ACC; and (3) myo-inositol levels were positively correlated with depressive symptoms in participants stabilised on buprenorphine." | 2.78 | Cingulate biochemistry in heroin users on substitution pharmacotherapy. ( Bora, E; Lubman, DI; MacKenzie, T; Roffel, K; Verdejo-García, A; Vilar-López, R; Yücel, M, 2013) |
| "Twenty patients had depression recurrence, and 23 patients reached AD discontinuation." | 1.62 | Choline elevation in amygdala region at recovery indicates longer survival without depressive episode: a magnetic resonance spectroscopy study. ( Bajs Janović, M; Erdeljić Turk, V; Foro, T; Henigsberg, N; Hrabač, P; Kalember, P; Ozretić, D; Radoš, M; Šarac, H; Savić, A; Šečić, A, 2021) |
| "Ketamine is an anesthetic with antidepressant properties." | 1.42 | The positive effect on ketamine as a priming adjuvant in antidepressant treatment. ( Dalla, C; Ferreira, C; Kokras, N; Melo, A; Pêgo, JM; Sousa, N; Ventura-Silva, AP, 2015) |
| "Agitation and depression are among the commonest behavioural and psychological symptoms exhibited by Alzheimer's disease patients." | 1.39 | Differences in brain metabolism associated with agitation and depression in Alzheimer's disease. ( Fuh, JL; Hung, CW; Lirng, JF; Tsai, CF; Wang, SJ, 2013) |
| "Moreover, depression was significantly correlated with titers of autoantibodies against DNA, NMDA receptors and cardiolipin." | 1.35 | Depression is an early disease manifestation in lupus-prone MRL/lpr mice. ( Campbell, SR; Cui, MH; Gao, HX; Gulinello, M; Hee-Hwang, J; Putterman, C; Zong, P, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (22.22) | 29.6817 |
| 2010's | 26 (57.78) | 24.3611 |
| 2020's | 7 (15.56) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, T | 1 |
| Li, R | 1 |
| Long, X | 1 |
| Chen, J | 1 |
| Ye, L | 1 |
| Wang, J | 2 |
| Jiang, G | 1 |
| Lv, J | 1 |
| Xie, X | 2 |
| Shi, Y | 2 |
| Ma, L | 2 |
| Yang, W | 2 |
| Pu, J | 2 |
| Shen, Y | 2 |
| Liu, Y | 2 |
| Zhang, H | 2 |
| Lv, F | 2 |
| Hu, L | 2 |
| Ho, CSH | 1 |
| Tay, GWN | 1 |
| Wee, HN | 1 |
| Ching, J | 1 |
| Pavlova, I | 1 |
| Ruda-Kucerova, J | 1 |
| Henigsberg, N | 1 |
| Savić, A | 1 |
| Radoš, M | 2 |
| Šarac, H | 1 |
| Šečić, A | 1 |
| Bajs Janović, M | 1 |
| Foro, T | 1 |
| Ozretić, D | 1 |
| Erdeljić Turk, V | 1 |
| Hrabač, P | 1 |
| Kalember, P | 1 |
| Zhou, T | 1 |
| Liu, J | 1 |
| Shangguan, J | 1 |
| Liu, X | 1 |
| Li, Z | 1 |
| Zhou, X | 1 |
| Ren, Y | 1 |
| Wang, C | 1 |
| Smith, GS | 1 |
| Oeltzschner, G | 1 |
| Gould, NF | 1 |
| Leoutsakos, JS | 1 |
| Nassery, N | 1 |
| Joo, JH | 1 |
| Kraut, MA | 1 |
| Edden, RAE | 1 |
| Barker, PB | 1 |
| Wijtenburg, SA | 1 |
| Rowland, LM | 1 |
| Workman, CI | 1 |
| Urrila, AS | 1 |
| Hakkarainen, A | 1 |
| Castaneda, A | 1 |
| Paunio, T | 1 |
| Marttunen, M | 1 |
| Lundbom, N | 1 |
| McGirr, A | 1 |
| LeDue, J | 1 |
| Chan, AW | 1 |
| Xie, Y | 1 |
| Murphy, TH | 1 |
| Miyamoto, Y | 1 |
| Iegaki, N | 1 |
| Fu, K | 1 |
| Ishikawa, Y | 1 |
| Sumi, K | 1 |
| Azuma, S | 1 |
| Uno, K | 1 |
| Muramatsu, SI | 1 |
| Nitta, A | 1 |
| Freed, RD | 1 |
| Hollenhorst, CN | 1 |
| Weiduschat, N | 1 |
| Mao, X | 1 |
| Kang, G | 1 |
| Shungu, DC | 1 |
| Gabbay, V | 2 |
| Tang, J | 1 |
| O'Neill, J | 1 |
| Alger, JR | 1 |
| Shen, Z | 1 |
| Johnson, MC | 1 |
| London, ED | 1 |
| Moriguchi, S | 1 |
| Takamiya, A | 1 |
| Noda, Y | 1 |
| Horita, N | 1 |
| Wada, M | 1 |
| Tsugawa, S | 1 |
| Plitman, E | 1 |
| Sano, Y | 1 |
| Tarumi, R | 1 |
| ElSalhy, M | 1 |
| Katayama, N | 1 |
| Ogyu, K | 1 |
| Miyazaki, T | 1 |
| Kishimoto, T | 1 |
| Graff-Guerrero, A | 1 |
| Meyer, JH | 1 |
| Blumberger, DM | 1 |
| Daskalakis, ZJ | 1 |
| Mimura, M | 1 |
| Nakajima, S | 1 |
| Mellen, EJ | 1 |
| Harper, DG | 1 |
| Ravichandran, C | 1 |
| Jensen, E | 1 |
| Silveri, M | 1 |
| Forester, BP | 1 |
| Miroshnichenko, II | 1 |
| Yakovleva, OB | 1 |
| Safarova, TP | 1 |
| Shipilova, ES | 1 |
| Baymeeva, NV | 1 |
| Muelly, ER | 1 |
| Moore, GJ | 1 |
| Bunce, SC | 1 |
| Mack, J | 1 |
| Bigler, DC | 1 |
| Morton, DH | 1 |
| Strauss, KA | 1 |
| Ezzati, A | 1 |
| Zimmerman, ME | 1 |
| Katz, MJ | 1 |
| Lipton, RB | 1 |
| Chamard, E | 1 |
| Henry, L | 1 |
| Boulanger, Y | 1 |
| Lassonde, M | 1 |
| Théoret, H | 1 |
| Tsai, CF | 1 |
| Hung, CW | 1 |
| Lirng, JF | 1 |
| Wang, SJ | 1 |
| Fuh, JL | 1 |
| Peng, GJ | 1 |
| Shi, BY | 1 |
| Tian, JS | 1 |
| Gao, S | 1 |
| Qin, XM | 1 |
| Jayaweera, HK | 1 |
| Lagopoulos, J | 1 |
| Duffy, SL | 1 |
| Lewis, SJ | 1 |
| Hermens, DF | 1 |
| Norrie, L | 1 |
| Hickie, IB | 1 |
| Naismith, SL | 1 |
| Melo, A | 1 |
| Kokras, N | 1 |
| Dalla, C | 1 |
| Ferreira, C | 1 |
| Ventura-Silva, AP | 1 |
| Sousa, N | 1 |
| Pêgo, JM | 1 |
| Thelen, C | 1 |
| Sens, J | 1 |
| Mauch, J | 1 |
| Pandit, R | 1 |
| Pitychoutis, PM | 1 |
| Kantorová, E | 1 |
| Poláček, H | 1 |
| Bittšanský, M | 2 |
| Baranovičová, E | 1 |
| Hnilicová, P | 1 |
| Čierny, D | 1 |
| Sivák, Š | 1 |
| Nosáľ, V | 1 |
| Zeleňák, K | 1 |
| Kurča, E | 1 |
| Gao, HX | 1 |
| Campbell, SR | 1 |
| Cui, MH | 1 |
| Zong, P | 1 |
| Hee-Hwang, J | 1 |
| Gulinello, M | 1 |
| Putterman, C | 1 |
| Liebes, L | 1 |
| Katz, Y | 1 |
| Liu, S | 2 |
| Mendoza, S | 1 |
| Babb, JS | 1 |
| Klein, RG | 1 |
| Gonen, O | 1 |
| Huang, Y | 1 |
| Chen, W | 1 |
| Li, Y | 2 |
| Wu, X | 1 |
| Shi, X | 1 |
| Geng, D | 1 |
| Lin, K | 1 |
| Taylor, MJ | 1 |
| Heaton, R | 1 |
| Franklin, D | 1 |
| Jernigan, T | 1 |
| Fennema-Notestine, C | 1 |
| McCutchan, A | 1 |
| Atkinson, JH | 1 |
| Ellis, RJ | 1 |
| McArthur, J | 1 |
| Morgello, S | 1 |
| Simpson, D | 1 |
| Collier, AC | 1 |
| Marra, C | 1 |
| Gelman, B | 1 |
| Clifford, D | 1 |
| Grant, I | 1 |
| Bédard, MJ | 1 |
| Chantal, S | 1 |
| Wang, X | 1 |
| Li, YH | 1 |
| Li, MH | 1 |
| Lu, J | 1 |
| Zhao, JG | 1 |
| Sun, XJ | 1 |
| Zhang, B | 1 |
| Ye, JL | 1 |
| Xi, G | 1 |
| Hui, J | 1 |
| Zhang, Z | 1 |
| Zhang, X | 1 |
| Teng, G | 1 |
| Chan, KC | 1 |
| Wu, EX | 1 |
| Nie, B | 1 |
| Shan, B | 1 |
| Li, L | 1 |
| Reynolds, GP | 1 |
| Husarova, V | 1 |
| Ondrejka, I | 1 |
| Kerna, V | 1 |
| Dobrota, D | 1 |
| Verdejo-García, A | 1 |
| Lubman, DI | 1 |
| Roffel, K | 1 |
| Vilar-López, R | 1 |
| Bora, E | 1 |
| MacKenzie, T | 1 |
| Yücel, M | 1 |
| Salehi, B | 1 |
| Preuss, N | 1 |
| van der Veen, JW | 1 |
| Shen, J | 1 |
| Neumeister, A | 1 |
| Drevets, WC | 1 |
| Hodgkinson, C | 1 |
| Goldman, D | 1 |
| Wendland, JR | 1 |
| Singleton, A | 1 |
| Gibbs, JR | 1 |
| Cookson, MR | 1 |
| Hasler, G | 1 |
| Grachev, ID | 1 |
| Ramachandran, TS | 1 |
| Thomas, PS | 1 |
| Szeverenyi, NM | 1 |
| Fredrickson, BE | 1 |
| Gruber, S | 1 |
| Frey, R | 1 |
| Mlynárik, V | 1 |
| Stadlbauer, A | 1 |
| Heiden, A | 1 |
| Kasper, S | 1 |
| Kemp, GJ | 1 |
| Moser, E | 1 |
| SIEGLER, PE | 1 |
| Johnson, PA | 1 |
| Hurley, RA | 1 |
| Benkelfat, C | 1 |
| Herpertz, SC | 1 |
| Taber, KH | 1 |
| Glodzik-Sobanska, L | 1 |
| Slowik, A | 1 |
| Kieltyka, A | 1 |
| Kozub, J | 1 |
| Sobiecka, B | 1 |
| Urbanik, A | 1 |
| Szczudlik, A | 1 |
| Gonul, AS | 1 |
| Kitis, O | 1 |
| Ozan, E | 1 |
| Akdeniz, F | 1 |
| Eker, C | 1 |
| Eker, OD | 1 |
| Vahip, S | 1 |
| Gilliam, FG | 1 |
| Maton, BM | 1 |
| Martin, RC | 1 |
| Sawrie, SM | 1 |
| Faught, RE | 1 |
| Hugg, JW | 1 |
| Viikinsalo, M | 1 |
| Kuzniecky, RI | 1 |
| Hong, ST | 1 |
| Choi, CB | 1 |
| Park, C | 1 |
| Hong, KS | 1 |
| Cheong, C | 1 |
| Jeon, YW | 1 |
| Choe, BY | 1 |
| Mu, J | 1 |
| Xie, P | 1 |
| Yang, ZS | 1 |
| Yang, DL | 1 |
| Lv, FJ | 1 |
| Luo, TY | 1 |
| Steingard, RJ | 1 |
| Yurgelun-Todd, DA | 1 |
| Hennen, J | 1 |
| Moore, JC | 1 |
| Moore, CM | 1 |
| Vakili, K | 1 |
| Young, AD | 1 |
| Katic, A | 1 |
| Beardslee, WR | 1 |
| Renshaw, PF | 1 |
| Consbruch, U | 1 |
| Orth, M | 1 |
| Degkwitz, R | 1 |
4 reviews available for aspartic acid and Depression
| Article | Year |
|---|---|
Brain metabolic derangements examined using
Topics: Animals; Aspartic Acid; Brain; Depression; Depressive Disorder, Major; Glutamic Acid; Glutamine; Pro | 2023 |
Glutamatergic neurometabolite levels in major depressive disorder: a systematic review and meta-analysis of proton magnetic resonance spectroscopy studies.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Depression; Depressive Disorder, Major; Female; Glutamic Aci | 2019 |
CURRENT STATUS OF DRUG TREATMENT IN THE DEPRESSIVE STATE.
Topics: Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Aspartic Acid; Benactyzine; Classif | 1964 |
Understanding emotion regulation in borderline personality disorder: contributions of neuroimaging.
Topics: Aspartic Acid; Borderline Personality Disorder; Brain; Brain Mapping; Choline; Compulsive Personalit | 2003 |
2 trials available for aspartic acid and Depression
| Article | Year |
|---|---|
Cingulate biochemistry in heroin users on substitution pharmacotherapy.
Topics: Adult; Aspartic Acid; Buprenorphine; Depression; Dose-Response Relationship, Drug; Female; Functiona | 2013 |
The effect of antidepressant treatment on N-acetyl aspartate levels of medial frontal cortex in drug-free depressed patients.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Aspartic Acid; Brain Mapping; Choline; Creatine; | 2006 |
39 other studies available for aspartic acid and Depression
| Article | Year |
|---|---|
Magnetic resonance imaging features of hippocampus and mechanism of neurocognitive dysfunction for antiepileptic drugs in treatment of depression rats.
Topics: Animals; Anticonvulsants; Aspartic Acid; Creatine; Depression; Hippocampus; Magnetic Resonance Imagi | 2022 |
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2023 |
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2023 |
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2023 |
Altered neurometabolite levels in the brains of patients with depression: A systematic analysis of magnetic resonance spectroscopy studies.
Topics: Aspartic Acid; Brain; Choline; Depression; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2023 |
The Utility of Amino Acid Metabolites in the Diagnosis of Major Depressive Disorder and Correlations with Depression Severity.
Topics: Amino Acids; Aspartic Acid; Biomarkers; Depression; Depressive Disorder, Major; Glutamic Acid; Glyci | 2023 |
Choline elevation in amygdala region at recovery indicates longer survival without depressive episode: a magnetic resonance spectroscopy study.
Topics: Adult; Amygdala; Antidepressive Agents; Aspartic Acid; Brain; Choline; Depression; Humans; Magnetic | 2021 |
Application of
Topics: Adult; Aspartic Acid; Choline; Creatine; Depression; Female; Frontal Lobe; Humans; Kidney Failure, C | 2020 |
Neurotransmitters and Neurometabolites in Late-Life Depression: A Preliminary Magnetic Resonance Spectroscopy Study at 7T.
Topics: Aspartic Acid; Creatine; Depression; Depressive Disorder, Major; Glutamic Acid; Gyrus Cinguli; Human | 2021 |
Frontal Cortex Myo-Inositol Is Associated with Sleep and Depression in Adolescents: A Proton Magnetic Resonance Spectroscopy Study.
Topics: Adolescent; Aspartic Acid; Creatine; Depression; Female; Frontal Lobe; Humans; Image Processing, Com | 2017 |
Cortical functional hyperconnectivity in a mouse model of depression and selective network effects of ketamine.
Topics: Animals; Antidepressive Agents; Aspartic Acid; Behavior, Animal; Cerebral Cortex; Depression; Diseas | 2017 |
Striatal N-Acetylaspartate Synthetase Shati/Nat8l Regulates Depression-Like Behaviors via mGluR3-Mediated Serotonergic Suppression in Mice.
Topics: Acetyltransferases; Animals; Aspartic Acid; Corpus Striatum; Depression; Dipeptides; Disease Models, | 2017 |
A pilot study of cortical glutathione in youth with depression.
Topics: Adolescent; Anhedonia; Aspartic Acid; Case-Control Studies; Child; Choline; Creatine; Depression; De | 2017 |
N-Acetyl and Glutamatergic Neurometabolites in Perisylvian Brain Regions of Methamphetamine Users.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Anxiety; Aspartic Acid; Central Nervous System Sti | 2019 |
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression.
Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Cre | 2019 |
[The content of N-acetylaspartate in depressed elderly patients during therapy with antidepressants and actovegin].
Topics: Aged; Antidepressive Agents; Aspartic Acid; Depression; Female; Heme; Humans; Male | 2019 |
Biochemical correlates of neuropsychiatric illness in maple syrup urine disease.
Topics: Adolescent; Adult; Affect; Anxiety; Aspartic Acid; Attention; Brain; Case-Control Studies; Child; Ch | 2013 |
Hippocampal correlates of depression in healthy elderly adults.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Creatine; Depression; Female; Geriatrics; Hippocampus; Human | 2013 |
A follow-up study of neurometabolic alterations in female concussed athletes.
Topics: Aspartic Acid; Athletes; Athletic Injuries; Brain Chemistry; Brain Concussion; Creatine; Depression; | 2014 |
Differences in brain metabolism associated with agitation and depression in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Creatine; Depression; Female; Gyrus Cinguli; Humans | 2013 |
[1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus].
Topics: Alanine; Animals; Antidepressive Agents; Aspartic Acid; Behavior, Animal; Chronic Disease; Depressio | 2014 |
Spectroscopic markers of memory impairment, symptom severity and age of onset in older people with lifetime depression: Discrete roles of N-acetyl aspartate and glutamate.
Topics: Aged; Aspartic Acid; Case-Control Studies; Cross-Sectional Studies; Depression; Female; Glutamic Aci | 2015 |
The positive effect on ketamine as a priming adjuvant in antidepressant treatment.
Topics: Animals; Antidepressive Agents; Anxiety; Aspartic Acid; Behavior, Animal; Brain; Depression; Depress | 2015 |
Repeated ketamine treatment induces sex-specific behavioral and neurochemical effects in mice.
Topics: Animals; Antidepressive Agents; Anxiety; Aspartic Acid; Depression; Female; Glutamic Acid; Hippocamp | 2016 |
Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue.
Topics: Adult; Aging; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectional Studies; Depre | 2017 |
Depression is an early disease manifestation in lupus-prone MRL/lpr mice.
Topics: Animals; Aspartic Acid; Autoantibodies; Brain; Cardiolipins; Choline; Chromatin; Creatine; Depressio | 2009 |
The kynurenine pathway in adolescent depression: preliminary findings from a proton MR spectroscopy study.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Aspartic Acid; Brain; Brain Mapping; Choline; Depression; Fem | 2010 |
Effects of antidepressant treatment on N-acetyl aspartate and choline levels in the hippocampus and thalami of post-stroke depression patients: a study using (1)H magnetic resonance spectroscopy.
Topics: Aged; Analysis of Variance; Antidepressive Agents; Aspartic Acid; Brain Mapping; Case-Control Studie | 2010 |
Effects of traumatic brain injury on cognitive functioning and cerebral metabolites in HIV-infected individuals.
Topics: Adult; Aspartic Acid; Brain Injuries; Cognition Disorders; Depression; Executive Function; Female; H | 2011 |
Brain magnetic resonance spectroscopy in obsessive-compulsive disorder: the importance of considering subclinical symptoms of anxiety and depression.
Topics: Adult; Anxiety; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Depression; Female; Function | 2011 |
Glutamate level detection by magnetic resonance spectroscopy in patients with post-stroke depression.
Topics: Aged; Aspartic Acid; Brain; Brain Mapping; Creatine; Depression; Female; Glutamic Acid; Humans; Inos | 2012 |
Learning and memory alterations are associated with hippocampal N-acetylaspartate in a rat model of depression as measured by 1H-MRS.
Topics: Animals; Aspartic Acid; Behavior, Animal; Citalopram; Creatine; Depression; Disease Models, Animal; | 2011 |
Hippocampal neurometabolite changes in depression treatment: a (1)H magnetic resonance spectroscopy study.
Topics: Adult; Antidepressive Agents; Aspartic Acid; Choline; Creatine; Depression; Female; Functional Later | 2012 |
Age-modulated association between prefrontal NAA and the BDNF gene.
Topics: Adolescent; Adult; Aging; Aspartic Acid; Brain-Derived Neurotrophic Factor; Depression; Depressive D | 2013 |
Association between dorsolateral prefrontal N-acetyl aspartate and depression in chronic back pain: an in vivo proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Back Pain; Chronic Disease; Depression; Female; Humans; Magnetic Resonance Spe | 2003 |
Quantification of metabolic differences in the frontal brain of depressive patients and controls obtained by 1H-MRS at 3 Tesla.
Topics: Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Depression; Fe | 2003 |
Reduced prefrontal N-acetylaspartate in stroke patients with apathy.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Depression; Female; Functional Laterality; Humans; Magnetic | 2005 |
Hippocampal 1H-MRSI correlates with severity of depression symptoms in temporal lobe epilepsy.
Topics: Adult; Aspartic Acid; Biomarkers; Creatine; Depression; Epilepsy, Temporal Lobe; Female; Hippocampus | 2007 |
Variation of the choline signal intensity in the dorsolateral prefrontal cortex of rats exposed to the forced swimming test as detected by in vivo 1H MR spectroscopy.
Topics: Animals; Aspartic Acid; Choline; Creatine; Depression; Magnetic Resonance Spectroscopy; Male; Prefro | 2007 |
1H magnetic resonance spectroscopy study of thalamus in treatment resistant depressive patients.
Topics: Adult; Aspartic Acid; Choline; Creatine; Depression; Female; Humans; Magnetic Resonance Spectroscopy | 2007 |
Increased orbitofrontal cortex levels of choline in depressed adolescents as detected by in vivo proton magnetic resonance spectroscopy.
Topics: Adolescent; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cytosol; Depression; Female; Fro | 2000 |
[Clinical administration of lithiumaspartate].
Topics: Acetates; Administration, Oral; Adolescent; Adult; Aspartic Acid; Biopharmaceutics; Bipolar Disorder | 1974 |